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The map label for this gene is atoC [H]

Identifier: 66044086

GI number: 66044086

Start: 941320

End: 942804

Strand: Reverse

Name: atoC [H]

Synonym: Psyr_0831

Alternate gene names: 66044086

Gene position: 942804-941320 (Counterclockwise)

Preceding gene: 66044087

Following gene: 66044085

Centisome position: 15.47

GC content: 60.74

Gene sequence:

>1485_bases
ATGTCGACGCGACGTCCACCGCGAACTGAGACCGTCGAGAGAACTGAATCAATGCCGCATATTTTGATCGTCGAAGACGA
AACGATTATCCGCTCAGCCCTGCGTCGCCTGCTTGAACGCAACCAGTATGAAGTCAGTGAAGCCGGCTCCGTTCAAGAGG
CTCAGGAACGCTTCAGCATCCCGTCGTTCGATCTGATCGTCAGCGACCTGCGCTTGCCCGGCGCACCCGGCACCGAGCTG
ATCAAGCTCGGCGAGGGCAAACCGGTGCTGATCATGACCAGTTACGCGAGCCTGCGCTCGGCAGTCGATTCGATGAAGAT
GGGCGCGGTGGACTACATCGCCAAACCCTTCGATCACGATGAAATGCTCCAGGCCGTCTCGCGGATCCTGCGTGATCGGC
AGACGGTCAAGCACCTTCAGGACGAACGCGGCGCCACCGCCCGGACCAGCAGCGCTGAAAAAGGCCCGGCACAGAACCAC
AATGGCGAGATCGGTATCATCGGCTCATGCCCGCCCATGCTGGATCTTTACAGCAAGATCCGCAAAGTTGCCCCGACTGA
TTCCAACGTCCTGATTCAAGGGGAATCGGGCACCGGTAAGGAACTGGTCGCCCGCGCCCTGCACAACCTCTCACGCCGCG
CCAAGGCGCCGATGATTTCCGTCAACTGTGCGGCCATTCCCGAATCGCTGATCGAGTCCGAACTGTTCGGTCATGAAAAA
GGCGCGTTCACCGGGGCCAGCGCAGGCCGCGCAGGTCTGGTCGAGGCTGCTGACGGTGGCACGCTGTTTCTCGATGAAAT
CGGCGAGCTGCCGCTGGAAGCCCAGGCTCGCCTGCTGCGCGTATTGCAGGAAGGCGAGATTCGCCGGGTCGGTTCGGTGC
AATCGCAAAAGGTCGACGTACGCCTGATTGCCGCGACCCACCGGGACCTGAAAACGCTGGCCAAAAATGGCGAGTTTCGT
GAAGACCTGTTCTATCGTCTGCACGTCATCGCCCTGAAGCTCCCGGCGCTGCGCGAACGTGGCAACGACATCCTGGAAAT
CGCCCATGCGTTCCTGGTTCGCCAGAGCGGCAAGGTCGGGCGCGACGACCTCAAATTTGCACACGACGCCGAACAAGCGA
TCCGCCATTACAGCTGGCCGGGTAACGTACGCGAGCTGGAAAACGCTGTGGAACGCTCGGTGATTCTGTGCGAGAACCCG
GAAATCACCGCTGACCTGCTGGGCATCGACATCGAGCTCGACGGTCTGGATGACGACGAGTACATGGGCATGGCGCCGTT
ACCGGGCTCTTCCGGCTCGTCGGGCAACGAGCCCGCCGAAGACCTGTCACTCGAAGACTATTTTCAGCACTTCGTTCTGG
AGCATCAGGATCACATGACTGAAACCGAGCTGGCGCGCAAGCTGGGCGTCAGTCGCAAATGTCTGTGGGAACGCCGTCAG
CGTCTGGGCATCCCGCGGCGCAAGGGCGTCGCCAGCGAGACATAA

Upstream 100 bases:

>100_bases
TATTCCATCGTTGAAGAGCATTATGGACAAATCACCATCGACAGCCCGGCCGATCCCGAGCAGCAGCGTGGAACCCGAAT
CAGGGTGACCTTGCCACGCC

Downstream 100 bases:

>100_bases
AACCGGCCCAGGGCTCTGGCACGCGGTGCGCAGGGCGGGGACAAACTGTTACCTCAAGCGTTTCACGTAACAAAAGCCGG
GTCTTACGGTAACGCAGGCC

Product: response regulator receiver:sigma-54 factor, interaction region

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSTRRPPRTETVERTESMPHILIVEDETIIRSALRRLLERNQYEVSEAGSVQEAQERFSIPSFDLIVSDLRLPGAPGTEL
IKLGEGKPVLIMTSYASLRSAVDSMKMGAVDYIAKPFDHDEMLQAVSRILRDRQTVKHLQDERGATARTSSAEKGPAQNH
NGEIGIIGSCPPMLDLYSKIRKVAPTDSNVLIQGESGTGKELVARALHNLSRRAKAPMISVNCAAIPESLIESELFGHEK
GAFTGASAGRAGLVEAADGGTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDVRLIAATHRDLKTLAKNGEFR
EDLFYRLHVIALKLPALRERGNDILEIAHAFLVRQSGKVGRDDLKFAHDAEQAIRHYSWPGNVRELENAVERSVILCENP
EITADLLGIDIELDGLDDDEYMGMAPLPGSSGSSGNEPAEDLSLEDYFQHFVLEHQDHMTETELARKLGVSRKCLWERRQ
RLGIPRRKGVASET

Sequences:

>Translated_494_residues
MSTRRPPRTETVERTESMPHILIVEDETIIRSALRRLLERNQYEVSEAGSVQEAQERFSIPSFDLIVSDLRLPGAPGTEL
IKLGEGKPVLIMTSYASLRSAVDSMKMGAVDYIAKPFDHDEMLQAVSRILRDRQTVKHLQDERGATARTSSAEKGPAQNH
NGEIGIIGSCPPMLDLYSKIRKVAPTDSNVLIQGESGTGKELVARALHNLSRRAKAPMISVNCAAIPESLIESELFGHEK
GAFTGASAGRAGLVEAADGGTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDVRLIAATHRDLKTLAKNGEFR
EDLFYRLHVIALKLPALRERGNDILEIAHAFLVRQSGKVGRDDLKFAHDAEQAIRHYSWPGNVRELENAVERSVILCENP
EITADLLGIDIELDGLDDDEYMGMAPLPGSSGSSGNEPAEDLSLEDYFQHFVLEHQDHMTETELARKLGVSRKCLWERRQ
RLGIPRRKGVASET
>Mature_493_residues
STRRPPRTETVERTESMPHILIVEDETIIRSALRRLLERNQYEVSEAGSVQEAQERFSIPSFDLIVSDLRLPGAPGTELI
KLGEGKPVLIMTSYASLRSAVDSMKMGAVDYIAKPFDHDEMLQAVSRILRDRQTVKHLQDERGATARTSSAEKGPAQNHN
GEIGIIGSCPPMLDLYSKIRKVAPTDSNVLIQGESGTGKELVARALHNLSRRAKAPMISVNCAAIPESLIESELFGHEKG
AFTGASAGRAGLVEAADGGTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDVRLIAATHRDLKTLAKNGEFRE
DLFYRLHVIALKLPALRERGNDILEIAHAFLVRQSGKVGRDDLKFAHDAEQAIRHYSWPGNVRELENAVERSVILCENPE
ITADLLGIDIELDGLDDDEYMGMAPLPGSSGSSGNEPAEDLSLEDYFQHFVLEHQDHMTETELARKLGVSRKCLWERRQR
LGIPRRKGVASET

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=471, Percent_Identity=42.4628450106157, Blast_Score=327, Evalue=9e-91,
Organism=Escherichia coli, GI1790437, Length=465, Percent_Identity=41.2903225806452, Blast_Score=317, Evalue=8e-88,
Organism=Escherichia coli, GI1790299, Length=386, Percent_Identity=43.7823834196891, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1788905, Length=393, Percent_Identity=41.2213740458015, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1789087, Length=240, Percent_Identity=52.5, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=54.5454545454545, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI87082117, Length=331, Percent_Identity=44.1087613293051, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789233, Length=238, Percent_Identity=50, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1786524, Length=332, Percent_Identity=43.0722891566265, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=47.1861471861472, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1787583, Length=338, Percent_Identity=35.7988165680473, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1789828, Length=301, Percent_Identity=34.5514950166113, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI87081858, Length=222, Percent_Identity=35.1351351351351, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790863, Length=128, Percent_Identity=32.8125, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 54683; Mature: 54552

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRRPPRTETVERTESMPHILIVEDETIIRSALRRLLERNQYEVSEAGSVQEAQERFSI
CCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHCC
PSFDLIVSDLRLPGAPGTELIKLGEGKPVLIMTSYASLRSAVDSMKMGAVDYIAKPFDHD
CCHHHHHHHHCCCCCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHCCHHHHHHCCCCHH
EMLQAVSRILRDRQTVKHLQDERGATARTSSAEKGPAQNHNGEIGIIGSCPPMLDLYSKI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHH
RKVAPTDSNVLIQGESGTGKELVARALHNLSRRAKAPMISVNCAAIPESLIESELFGHEK
HHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCC
GAFTGASAGRAGLVEAADGGTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDV
CCCCCCCCCCCCEEEECCCCEEEHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCEEE
RLIAATHRDLKTLAKNGEFREDLFYRLHVIALKLPALRERGNDILEIAHAFLVRQSGKVG
EEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
RDDLKFAHDAEQAIRHYSWPGNVRELENAVERSVILCENPEITADLLGIDIELDGLDDDE
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCEEEECCCCCEEEEEEEEEEECCCCCCC
YMGMAPLPGSSGSSGNEPAEDLSLEDYFQHFVLEHQDHMTETELARKLGVSRKCLWERRQ
CCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
RLGIPRRKGVASET
HCCCCHHCCCCCCC
>Mature Secondary Structure 
STRRPPRTETVERTESMPHILIVEDETIIRSALRRLLERNQYEVSEAGSVQEAQERFSI
CCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHCC
PSFDLIVSDLRLPGAPGTELIKLGEGKPVLIMTSYASLRSAVDSMKMGAVDYIAKPFDHD
CCHHHHHHHHCCCCCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHCCHHHHHHCCCCHH
EMLQAVSRILRDRQTVKHLQDERGATARTSSAEKGPAQNHNGEIGIIGSCPPMLDLYSKI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHH
RKVAPTDSNVLIQGESGTGKELVARALHNLSRRAKAPMISVNCAAIPESLIESELFGHEK
HHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCC
GAFTGASAGRAGLVEAADGGTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDV
CCCCCCCCCCCCEEEECCCCEEEHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCEEE
RLIAATHRDLKTLAKNGEFREDLFYRLHVIALKLPALRERGNDILEIAHAFLVRQSGKVG
EEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
RDDLKFAHDAEQAIRHYSWPGNVRELENAVERSVILCENPEITADLLGIDIELDGLDDDE
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCEEEECCCCCEEEEEEEEEEECCCCCCC
YMGMAPLPGSSGSSGNEPAEDLSLEDYFQHFVLEHQDHMTETELARKLGVSRKCLWERRQ
CCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
RLGIPRRKGVASET
HCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]