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The map label for this gene is phoP [H]

Identifier: 66044043

GI number: 66044043

Start: 895052

End: 895420

Strand: Reverse

Name: phoP [H]

Synonym: Psyr_0788

Alternate gene names: 66044043

Gene position: 895420-895052 (Counterclockwise)

Preceding gene: 66044044

Following gene: 66044042

Centisome position: 14.69

GC content: 56.64

Gene sequence:

>369_bases
ATGGCTAAGAGTGTATTGGTGGTCGACGATTCAAGCAGCGTCCGGCAAGTCGTCGGTATCGCGCTGAAGAGTGCCGGATA
CGACGTTATCGAAGCCTGTGACGGGAAGGATGCACTGGGCAAGCTCACCGGGCAGAAAGTGCACCTGATCATCAGCGACG
TGAACATGCCGAACATGGACGGCATCACTTTCGTCAAGGAAGTGAAGAAGCTGGCCAGCTACAAGTTCACGCCCATCATC
ATGCTGACCACCGAATCCCAGGAATCGAAAAAGGCCGAAGGTCAGGCCGCAGGCGCCAAGGCGTGGGTCGTCAAACCGTT
TCAGCCGGCACAAATGCTCGCAGCGGTTTCCAAGCTCATCCTGCCCTGA

Upstream 100 bases:

>100_bases
GGAGTCTACCTACGCGACCGACGAGCAACGTCGCACTCACCGAGGTGAATCGGCAGCACAGCAGGATTCGCAGGAAATCA
CGTTTTTCTAGGAGTAAATC

Downstream 100 bases:

>100_bases
GACCCAGGCCCCTGGAGGCCAGCATGCCCACGCCAGACGAGAGCGCCAACGACACTGCACGCGTGCAGATAGACGGCGAG
TTGACGATCTACACCGTGAC

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MAKSVLVVDDSSSVRQVVGIALKSAGYDVIEACDGKDALGKLTGQKVHLIISDVNMPNMDGITFVKEVKKLASYKFTPII
MLTTESQESKKAEGQAAGAKAWVVKPFQPAQMLAAVSKLILP

Sequences:

>Translated_122_residues
MAKSVLVVDDSSSVRQVVGIALKSAGYDVIEACDGKDALGKLTGQKVHLIISDVNMPNMDGITFVKEVKKLASYKFTPII
MLTTESQESKKAEGQAAGAKAWVVKPFQPAQMLAAVSKLILP
>Mature_121_residues
AKSVLVVDDSSSVRQVVGIALKSAGYDVIEACDGKDALGKLTGQKVHLIISDVNMPNMDGITFVKEVKKLASYKFTPIIM
LTTESQESKKAEGQAAGAKAWVVKPFQPAQMLAAVSKLILP

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788191, Length=116, Percent_Identity=39.6551724137931, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1786599, Length=125, Percent_Identity=32.8, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=35.3448275862069, Blast_Score=70, Evalue=4e-14,
Organism=Escherichia coli, GI1790863, Length=117, Percent_Identity=28.2051282051282, Blast_Score=68, Evalue=1e-13,
Organism=Escherichia coli, GI1786911, Length=104, Percent_Identity=33.6538461538462, Blast_Score=66, Evalue=5e-13,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=31.8965517241379, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=116, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI87082012, Length=112, Percent_Identity=31.25, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=34.3137254901961, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1788550, Length=103, Percent_Identity=31.0679611650485, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=31.8965517241379, Blast_Score=59, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13005; Mature: 12874

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSVLVVDDSSSVRQVVGIALKSAGYDVIEACDGKDALGKLTGQKVHLIISDVNMPNMD
CCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHCCCCEEEEEEEECCCCCCC
GITFVKEVKKLASYKFTPIIMLTTESQESKKAEGQAAGAKAWVVKPFQPAQMLAAVSKLI
CHHHHHHHHHHHCCCCCEEEEEEECCCHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHH
LP
CC
>Mature Secondary Structure 
AKSVLVVDDSSSVRQVVGIALKSAGYDVIEACDGKDALGKLTGQKVHLIISDVNMPNMD
CCCEEEEECCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHCCCCEEEEEEEECCCCCCC
GITFVKEVKKLASYKFTPIIMLTTESQESKKAEGQAAGAKAWVVKPFQPAQMLAAVSKLI
CHHHHHHHHHHHCCCCCEEEEEEECCCHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHH
LP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]