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The map label for this gene is dapE [H]

Identifier: 66044026

GI number: 66044026

Start: 875599

End: 876741

Strand: Reverse

Name: dapE [H]

Synonym: Psyr_0771

Alternate gene names: 66044026

Gene position: 876741-875599 (Counterclockwise)

Preceding gene: 66044027

Following gene: 66044025

Centisome position: 14.39

GC content: 63.25

Gene sequence:

>1143_bases
ATGCTCGATGACCCTATAGCCCTGACCCGAGCCCTGCTGGCGTTCCAGACCCTCAACCCGCCGGGCGATGAAGAAGCGTG
TGCGGCTTTTCTTGCCGAGCAGCTGACCCGCCACGGATTTGTCTGCGAGCTGCAGCGTTTCGGTGAGCGCCGTTTCAATC
TGGTCGCCTGGCTTGAGGGCGACGGCCCCGGCAAACCGCTGGGGTTCACCGGCCACCTGGATACCGTGCCGCTCGGCAAT
GCCACCTGGAGTCACTCGCCGTTTGCCGGTGAGATCGTCGATGGCCGGCTGTACGGGCGAGGGTCCAGCGACATGAAAGC
GGGCATTGCCGCCTTCATCGTGGCCTGCCAGCGCAGCCGTGATTCCATTCGGCGCGGGCCCGGCGTTCGTCTGATACTCA
CCGGCGGAGAGGAAACCGGCTGTGACGGCGCCAAGGCCCTGTGCAGTGACGCGCCCCATTTGCTTGGCGAACTGGGCGCA
CTGCTGATCGGAGAGCCGACGGCCAACTACCCGATACTCGGACACAAAGGCGCGTTATGGCTGTGCTGCGCCAGCCATGG
CCTGACGGCCCACGGAGCGATGCCGGAAGAAGGCGTGAACGCTATCTATCTGGCCGCCGAACACATTGGCCGCGCACAGA
CCTTTGAAGTAGGCCCCGCGCATCCGCTCATGCGCAAGCCGACGCTGAACGTCGGCACTATCAGCGGCGGTCTGAACATC
AACTCGGTGCCGGACTACGCAGCGTTCACCCTGGACCTGCGCACTGCACCGAATCTGGACCACGACGAGATTCGCGGACG
ACTGGCGGCCCATCTGGGCAGCAGCGCGGAACTGAGCACCCTGATTGATCTGCCTGGTATCTGTGCCAGCCCCGACGAGC
CTTGGGTGCAACAGGTTTTTGCACGCTGTCAGGCCTTGCATGACGCCCCTCTGGAGGAAAAGGCGGTGCCCTACTTTACC
GATGCCGCGGTGCTGCTCCCCGCCATCGGCTATCCGCCCACCCTTATTCTCGGCCCGGGAGAGCCCGGCATGGCGCACAA
GGTCGATGAGTATTGTGAAGTCGACAAACTTCAGCAATGCGTCGAACTGTATGCCGGATTGATCGAAGACTGGACAGTCA
TGCACGCGCCGATGAACGACTGA

Upstream 100 bases:

>100_bases
ACACTGGCTGCCGGAAGCTTTTCTCGACTGGGAAGGCTATCGCCGCTTCTGGATCAACAGCCTCGACTGGCTGACCCGCC
GTACCTGACCGGAGGCTCCG

Downstream 100 bases:

>100_bases
CGCAAGATACTCTCACCAGCCCTTCATAGCCCTCCTCGTCGGCATTCGCTCGGCTCACATTCAAACCGGCTGCGCAAAGC
AGCCACTCACCTGGAACGTG

Product: peptidase M20:peptidase M20

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MLDDPIALTRALLAFQTLNPPGDEEACAAFLAEQLTRHGFVCELQRFGERRFNLVAWLEGDGPGKPLGFTGHLDTVPLGN
ATWSHSPFAGEIVDGRLYGRGSSDMKAGIAAFIVACQRSRDSIRRGPGVRLILTGGEETGCDGAKALCSDAPHLLGELGA
LLIGEPTANYPILGHKGALWLCCASHGLTAHGAMPEEGVNAIYLAAEHIGRAQTFEVGPAHPLMRKPTLNVGTISGGLNI
NSVPDYAAFTLDLRTAPNLDHDEIRGRLAAHLGSSAELSTLIDLPGICASPDEPWVQQVFARCQALHDAPLEEKAVPYFT
DAAVLLPAIGYPPTLILGPGEPGMAHKVDEYCEVDKLQQCVELYAGLIEDWTVMHAPMND

Sequences:

>Translated_380_residues
MLDDPIALTRALLAFQTLNPPGDEEACAAFLAEQLTRHGFVCELQRFGERRFNLVAWLEGDGPGKPLGFTGHLDTVPLGN
ATWSHSPFAGEIVDGRLYGRGSSDMKAGIAAFIVACQRSRDSIRRGPGVRLILTGGEETGCDGAKALCSDAPHLLGELGA
LLIGEPTANYPILGHKGALWLCCASHGLTAHGAMPEEGVNAIYLAAEHIGRAQTFEVGPAHPLMRKPTLNVGTISGGLNI
NSVPDYAAFTLDLRTAPNLDHDEIRGRLAAHLGSSAELSTLIDLPGICASPDEPWVQQVFARCQALHDAPLEEKAVPYFT
DAAVLLPAIGYPPTLILGPGEPGMAHKVDEYCEVDKLQQCVELYAGLIEDWTVMHAPMND
>Mature_380_residues
MLDDPIALTRALLAFQTLNPPGDEEACAAFLAEQLTRHGFVCELQRFGERRFNLVAWLEGDGPGKPLGFTGHLDTVPLGN
ATWSHSPFAGEIVDGRLYGRGSSDMKAGIAAFIVACQRSRDSIRRGPGVRLILTGGEETGCDGAKALCSDAPHLLGELGA
LLIGEPTANYPILGHKGALWLCCASHGLTAHGAMPEEGVNAIYLAAEHIGRAQTFEVGPAHPLMRKPTLNVGTISGGLNI
NSVPDYAAFTLDLRTAPNLDHDEIRGRLAAHLGSSAELSTLIDLPGICASPDEPWVQQVFARCQALHDAPLEEKAVPYFT
DAAVLLPAIGYPPTLILGPGEPGMAHKVDEYCEVDKLQQCVELYAGLIEDWTVMHAPMND

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=388, Percent_Identity=23.4536082474227, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1790395, Length=394, Percent_Identity=30.4568527918782, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1788816, Length=276, Percent_Identity=29.3478260869565, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789236, Length=379, Percent_Identity=25.5936675461741, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551016, Length=379, Percent_Identity=24.802110817942, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24649206, Length=390, Percent_Identity=22.3076923076923, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 40550; Mature: 40550

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDDPIALTRALLAFQTLNPPGDEEACAAFLAEQLTRHGFVCELQRFGERRFNLVAWLEG
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHCCCCEEEEEEEEC
DGPGKPLGFTGHLDTVPLGNATWSHSPFAGEIVDGRLYGRGSSDMKAGIAAFIVACQRSR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCEEECCCCCHHHHHHHHHHHHHHHHH
DSIRRGPGVRLILTGGEETGCDGAKALCSDAPHLLGELGALLIGEPTANYPILGHKGALW
HHHHCCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHCCEEECCCCCCCCEECCCCCEE
LCCASHGLTAHGAMPEEGVNAIYLAAEHIGRAQTFEVGPAHPLMRKPTLNVGTISGGLNI
EEEECCCCEECCCCCCCCCCEEEEEHHHCCCCEEEECCCCCCCCCCCCCCEEEEECCCCC
NSVPDYAAFTLDLRTAPNLDHDEIRGRLAAHLGSSAELSTLIDLPGICASPDEPWVQQVF
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHH
ARCQALHDAPLEEKAVPYFTDAAVLLPAIGYPPTLILGPGEPGMAHKVDEYCEVDKLQQC
HHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
VELYAGLIEDWTVMHAPMND
HHHHHHHHHCCEEEECCCCC
>Mature Secondary Structure
MLDDPIALTRALLAFQTLNPPGDEEACAAFLAEQLTRHGFVCELQRFGERRFNLVAWLEG
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHCCCCEEEEEEEEC
DGPGKPLGFTGHLDTVPLGNATWSHSPFAGEIVDGRLYGRGSSDMKAGIAAFIVACQRSR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCEEECCCCCHHHHHHHHHHHHHHHHH
DSIRRGPGVRLILTGGEETGCDGAKALCSDAPHLLGELGALLIGEPTANYPILGHKGALW
HHHHCCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHCCEEECCCCCCCCEECCCCCEE
LCCASHGLTAHGAMPEEGVNAIYLAAEHIGRAQTFEVGPAHPLMRKPTLNVGTISGGLNI
EEEECCCCEECCCCCCCCCCEEEEEHHHCCCCEEEECCCCCCCCCCCCCCEEEEECCCCC
NSVPDYAAFTLDLRTAPNLDHDEIRGRLAAHLGSSAELSTLIDLPGICASPDEPWVQQVF
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHH
ARCQALHDAPLEEKAVPYFTDAAVLLPAIGYPPTLILGPGEPGMAHKVDEYCEVDKLQQC
HHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
VELYAGLIEDWTVMHAPMND
HHHHHHHHHCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA