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The map label for this gene is yfcX [C]

Identifier: 66044001

GI number: 66044001

Start: 845696

End: 846529

Strand: Reverse

Name: yfcX [C]

Synonym: Psyr_0742

Alternate gene names: 66044001

Gene position: 846529-845696 (Counterclockwise)

Preceding gene: 66044002

Following gene: 66044000

Centisome position: 13.89

GC content: 57.07

Gene sequence:

>834_bases
ATGAGATCTCTACTGACCCAGTTCACGATCACCGATGTAGCGCCGGGATACTGGCGAGTGACTTTCAACAATCCGCCCCT
CAACTTTTGCGATCCGGACACCCTCATCGAGTTGCAGCAGATCGCCACTCTTATCGAATCCGATGACGCGTTGCGGGTGG
TCGTATTCGATAGCGATGACCAGGATTTTTTTGTCAATCACTATGATGTATCCCGGGTCGCCGATTTTCCCCTGCAGCCT
GGACCTACTGGACTGCCAACGTTCATCGATGCCACCACACGGTTGACCACCTCACCTGTTGTGACCATCGCCTCAATTCG
GGGTCGCACGCGTGGCGGGGGTTCTGAGATTGCTCTGGCATGTGATATGCGATTTGCAAGCCTTGAGCGTGCGATCTTTG
CCCAGATCGAGGTCGGAGCAGGCGTGTTCCCAGGCGGTGGCGCAACGGAGCGACTACCACTCCTCGTCGGGCGGGCAAGG
GCACTCGAAATCGTCCTAGGCAGTGATGATTTCGACGCAGCCACTGCAGCGCTTTACGGGTGGGTGAACCGCGCCCTCCC
CGATAATGAACTCGACGCATTTGTCGACAATCTCGCTCGACGCATCGCGTCGTTCGACAAGCCTGCGCTGGCCGAGGCCA
AAGGGCTGATTAACCGCAGAACCCTGCCATCCGCTGAGGATCTTATGCAAACACAGGAAGTTTTCCTTAATGCGTTCTCT
TGGCCGACGGTTCATGAGCGGGGAGCCCGCATAGCGCAAAAGCGCGACGAAGTGGGGGCTGACTTCGAGGCCCGGATGGG
CTATCACCTCGGCAATCTCAGAACCAATACCTAA

Upstream 100 bases:

>100_bases
CTGACATCCTGATTACGGTCGTCATCCTGATGCTATACAGCGAGAGATGCCTGCATTCTCGATACGTCCAATACTCAGCA
TCCTATAAGGAATATCCTGA

Downstream 100 bases:

>100_bases
CAGCACGAATAGCAATCGTCTTTGGTGCGTCCGAAGCCTTGGCGTACTTCGAATGAACTGGGTCGCACTCACACTCTTTG
GGATAAACTGGTATCCCATT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MRSLLTQFTITDVAPGYWRVTFNNPPLNFCDPDTLIELQQIATLIESDDALRVVVFDSDDQDFFVNHYDVSRVADFPLQP
GPTGLPTFIDATTRLTTSPVVTIASIRGRTRGGGSEIALACDMRFASLERAIFAQIEVGAGVFPGGGATERLPLLVGRAR
ALEIVLGSDDFDAATAALYGWVNRALPDNELDAFVDNLARRIASFDKPALAEAKGLINRRTLPSAEDLMQTQEVFLNAFS
WPTVHERGARIAQKRDEVGADFEARMGYHLGNLRTNT

Sequences:

>Translated_277_residues
MRSLLTQFTITDVAPGYWRVTFNNPPLNFCDPDTLIELQQIATLIESDDALRVVVFDSDDQDFFVNHYDVSRVADFPLQP
GPTGLPTFIDATTRLTTSPVVTIASIRGRTRGGGSEIALACDMRFASLERAIFAQIEVGAGVFPGGGATERLPLLVGRAR
ALEIVLGSDDFDAATAALYGWVNRALPDNELDAFVDNLARRIASFDKPALAEAKGLINRRTLPSAEDLMQTQEVFLNAFS
WPTVHERGARIAQKRDEVGADFEARMGYHLGNLRTNT
>Mature_277_residues
MRSLLTQFTITDVAPGYWRVTFNNPPLNFCDPDTLIELQQIATLIESDDALRVVVFDSDDQDFFVNHYDVSRVADFPLQP
GPTGLPTFIDATTRLTTSPVVTIASIRGRTRGGGSEIALACDMRFASLERAIFAQIEVGAGVFPGGGATERLPLLVGRAR
ALEIVLGSDDFDAATAALYGWVNRALPDNELDAFVDNLARRIASFDKPALAEAKGLINRRTLPSAEDLMQTQEVFLNAFS
WPTVHERGARIAQKRDEVGADFEARMGYHLGNLRTNT

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=201, Percent_Identity=32.8358208955224, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI20127408, Length=241, Percent_Identity=26.5560165975104, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788682, Length=174, Percent_Identity=28.735632183908, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787659, Length=220, Percent_Identity=28.1818181818182, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788597, Length=206, Percent_Identity=25.7281553398058, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI221142681, Length=247, Percent_Identity=27.1255060728745, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=29.9180327868852, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=182, Percent_Identity=29.6703296703297, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17554946, Length=239, Percent_Identity=24.6861924686192, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129971, Length=200, Percent_Identity=25, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653477, Length=200, Percent_Identity=25, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 30391; Mature: 30391

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLLTQFTITDVAPGYWRVTFNNPPLNFCDPDTLIELQQIATLIESDDALRVVVFDSDD
CCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
QDFFVNHYDVSRVADFPLQPGPTGLPTFIDATTRLTTSPVVTIASIRGRTRGGGSEIALA
CCEEEEECCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEE
CDMRFASLERAIFAQIEVGAGVFPGGGATERLPLLVGRARALEIVLGSDDFDAATAALYG
ECCHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCCHHHHHHHHH
WVNRALPDNELDAFVDNLARRIASFDKPALAEAKGLINRRTLPSAEDLMQTQEVFLNAFS
HHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
WPTVHERGARIAQKRDEVGADFEARMGYHLGNLRTNT
CCCHHHHHHHHHHHHHHCCCCHHHHCCEEECCCCCCC
>Mature Secondary Structure
MRSLLTQFTITDVAPGYWRVTFNNPPLNFCDPDTLIELQQIATLIESDDALRVVVFDSDD
CCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
QDFFVNHYDVSRVADFPLQPGPTGLPTFIDATTRLTTSPVVTIASIRGRTRGGGSEIALA
CCEEEEECCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEE
CDMRFASLERAIFAQIEVGAGVFPGGGATERLPLLVGRARALEIVLGSDDFDAATAALYG
ECCHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCCHHHHHHHHH
WVNRALPDNELDAFVDNLARRIASFDKPALAEAKGLINRRTLPSAEDLMQTQEVFLNAFS
HHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
WPTVHERGARIAQKRDEVGADFEARMGYHLGNLRTNT
CCCHHHHHHHHHHHHHHCCCCHHHHCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA