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The map label for this gene is xanP [H]

Identifier: 66043943

GI number: 66043943

Start: 765956

End: 767353

Strand: Reverse

Name: xanP [H]

Synonym: Psyr_0676

Alternate gene names: 66043943

Gene position: 767353-765956 (Counterclockwise)

Preceding gene: 66043944

Following gene: 66043942

Centisome position: 12.59

GC content: 62.8

Gene sequence:

>1398_bases
ATGCAGCCTGAAACACTCGACAACGATGACCTGATCTACGGCCTGAACGATCGCCCCAAACCCTGGACGGCCATTTTGGC
AGCGTTCCAGCACGTTCTCGCCAGCTTCGTCGGGATCATCACCCCGCCCCTGATCATCGGCTCGACCCTCGGCCTGACCC
CATACATGCCGTACCTGATCAGCATGGCCTTGATGGTCTCGGGCACCGGTACGTTCATCCAGGCGCGCCGCCCGTTCGGC
ATCGGCGCGGGCATGATCTGTCTGCAAGGCACCAGCTTCGCGTTCCTGGGCGCCGTGTTGTCCGCAGGCTTTCTGGTCAA
ACAGCGCGGCGGCAGCCCGGAGGACATCATGGCGATGATCTTCGGCGTGTGCTTTTTCGGTGCGCTGGTGCAGATCGCGC
TGAGTCGCTGCATTAGCCAGCTGCGAAGGGTCATCACGCCGCTGGTGACCGGTATTGTCATCACGTTGATTGGTGTGAGC
CTGATCAAGGTGGGCGTGACAGACCTGGGCGGCGGTTTCAATGCGCCGGACTTCGGCGCCCCGGTGAACCTGGCGCTGGG
CGCGTTCGTTCTGGCCGTGATCATTGTGCTCAATCGCTCGAATACGCCCTGGGTACGTTTGTCAGCCATCATCATCGGCC
TGGCGGTCGGCAGTCTGGCCGCCTGGTTCAGCGGCAAGCTGGTGCCGCAAGCCCTTCACGACCTGCCGTTGATCAGCGTA
CCGGTGCCCTTCCGCTTCGGCTTCAATTTCGACTGGAGCGCTTTCCTGCCAGTCGCGCTGATTTATCTGATCAGCAGCAT
CGAAACAGTCGGCGACCTGACCGCCAATTGCATGCTCGCGCGCCAGCCCATCAGCGGCCCGAGCTACCTGGCACGCCTCA
AGGGCGGCGTGCTCGGCGATGGCGTGAGCTGCATGATCGCCGCGACCTTCAGCGCATTTCCCAATACCACCTTTGCGCAA
AACAACGGCGTGATCCAGTTGACCGGCGTTGCCAGTCGCTACGTCGGGCTGTACATCGGCGCGGTGCTGTTCGTACTCGG
GCTGTTTCCGCACATCGGCGCCATCGTCCAGCAGATCCCCAAGCCGGTGCTCGGCGGCGCAACGCTGGTCATGTTCGGCA
GCGTCGCCGCCGCCGGGGTGCGCATTCTGGCCCAGTCGCCGCTGGACCGACGCAGCATGCTGATCATTGCGACGTCCTTG
GGTGTCGGTCTGGGCATTGCGGCGCAGCCTGCGCTGCTGCACCAATTGCCGAAACTGGTGCAGAACCTGTTCGATTCGGC
GATCACCAGCGGCGGCATCACGGCCATTGTCATGTGCCTGCTGATTCCGGAAGGCAAAGTCACCGCCGCTACGACCGACG
CCGTAACGGAACCCGAACCTGTGGAGCAACCACGATAA

Upstream 100 bases:

>100_bases
GGACTCAAATAAAAATAACCTGAGCAACTGGACAGTTTTTTGCAGTAGTCCCGGACAACGACACGCCAGCACATGGCATT
TCCCCGTCCGAGAACTTGCC

Downstream 100 bases:

>100_bases
CTTTGCATGCCGCGCCCGCACCGACGCTTGCGAGATTCTCGCCGGTGCGCTATCTGTTCATCCGTCGCGCCCTACGACCT
GTCCGGAATTGCCCATGACC

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MQPETLDNDDLIYGLNDRPKPWTAILAAFQHVLASFVGIITPPLIIGSTLGLTPYMPYLISMALMVSGTGTFIQARRPFG
IGAGMICLQGTSFAFLGAVLSAGFLVKQRGGSPEDIMAMIFGVCFFGALVQIALSRCISQLRRVITPLVTGIVITLIGVS
LIKVGVTDLGGGFNAPDFGAPVNLALGAFVLAVIIVLNRSNTPWVRLSAIIIGLAVGSLAAWFSGKLVPQALHDLPLISV
PVPFRFGFNFDWSAFLPVALIYLISSIETVGDLTANCMLARQPISGPSYLARLKGGVLGDGVSCMIAATFSAFPNTTFAQ
NNGVIQLTGVASRYVGLYIGAVLFVLGLFPHIGAIVQQIPKPVLGGATLVMFGSVAAAGVRILAQSPLDRRSMLIIATSL
GVGLGIAAQPALLHQLPKLVQNLFDSAITSGGITAIVMCLLIPEGKVTAATTDAVTEPEPVEQPR

Sequences:

>Translated_465_residues
MQPETLDNDDLIYGLNDRPKPWTAILAAFQHVLASFVGIITPPLIIGSTLGLTPYMPYLISMALMVSGTGTFIQARRPFG
IGAGMICLQGTSFAFLGAVLSAGFLVKQRGGSPEDIMAMIFGVCFFGALVQIALSRCISQLRRVITPLVTGIVITLIGVS
LIKVGVTDLGGGFNAPDFGAPVNLALGAFVLAVIIVLNRSNTPWVRLSAIIIGLAVGSLAAWFSGKLVPQALHDLPLISV
PVPFRFGFNFDWSAFLPVALIYLISSIETVGDLTANCMLARQPISGPSYLARLKGGVLGDGVSCMIAATFSAFPNTTFAQ
NNGVIQLTGVASRYVGLYIGAVLFVLGLFPHIGAIVQQIPKPVLGGATLVMFGSVAAAGVRILAQSPLDRRSMLIIATSL
GVGLGIAAQPALLHQLPKLVQNLFDSAITSGGITAIVMCLLIPEGKVTAATTDAVTEPEPVEQPR
>Mature_465_residues
MQPETLDNDDLIYGLNDRPKPWTAILAAFQHVLASFVGIITPPLIIGSTLGLTPYMPYLISMALMVSGTGTFIQARRPFG
IGAGMICLQGTSFAFLGAVLSAGFLVKQRGGSPEDIMAMIFGVCFFGALVQIALSRCISQLRRVITPLVTGIVITLIGVS
LIKVGVTDLGGGFNAPDFGAPVNLALGAFVLAVIIVLNRSNTPWVRLSAIIIGLAVGSLAAWFSGKLVPQALHDLPLISV
PVPFRFGFNFDWSAFLPVALIYLISSIETVGDLTANCMLARQPISGPSYLARLKGGVLGDGVSCMIAATFSAFPNTTFAQ
NNGVIQLTGVASRYVGLYIGAVLFVLGLFPHIGAIVQQIPKPVLGGATLVMFGSVAAAGVRILAQSPLDRRSMLIIATSL
GVGLGIAAQPALLHQLPKLVQNLFDSAITSGGITAIVMCLLIPEGKVTAATTDAVTEPEPVEQPR

Specific function: Specific, proton motive force-dependent high-affinity transporter for xanthine [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790087, Length=446, Percent_Identity=47.7578475336323, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI87082178, Length=458, Percent_Identity=44.5414847161572, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI87082181, Length=439, Percent_Identity=32.3462414578588, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI87081818, Length=437, Percent_Identity=25.4004576659039, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788843, Length=162, Percent_Identity=31.4814814814815, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17541904, Length=508, Percent_Identity=23.0314960629921, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17558856, Length=434, Percent_Identity=25.3456221198157, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48652; Mature: 48652

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPETLDNDDLIYGLNDRPKPWTAILAAFQHVLASFVGIITPPLIIGSTLGLTPYMPYLI
CCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHH
SMALMVSGTGTFIQARRPFGIGAGMICLQGTSFAFLGAVLSAGFLVKQRGGSPEDIMAMI
HHHHHHCCCCCEEEECCCCCCCCCCCEECCCHHHHHHHHHHCCHHEECCCCCHHHHHHHH
FGVCFFGALVQIALSRCISQLRRVITPLVTGIVITLIGVSLIKVGVTDLGGGFNAPDFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PVNLALGAFVLAVIIVLNRSNTPWVRLSAIIIGLAVGSLAAWFSGKLVPQALHDLPLISV
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEE
PVPFRFGFNFDWSAFLPVALIYLISSIETVGDLTANCMLARQPISGPSYLARLKGGVLGD
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCCCCCC
GVSCMIAATFSAFPNTTFAQNNGVIQLTGVASRYVGLYIGAVLFVLGLFPHIGAIVQQIP
CHHHHHHHHHHHCCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPVLGGATLVMFGSVAAAGVRILAQSPLDRRSMLIIATSLGVGLGIAAQPALLHQLPKLV
CCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
QNLFDSAITSGGITAIVMCLLIPEGKVTAATTDAVTEPEPVEQPR
HHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MQPETLDNDDLIYGLNDRPKPWTAILAAFQHVLASFVGIITPPLIIGSTLGLTPYMPYLI
CCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHH
SMALMVSGTGTFIQARRPFGIGAGMICLQGTSFAFLGAVLSAGFLVKQRGGSPEDIMAMI
HHHHHHCCCCCEEEECCCCCCCCCCCEECCCHHHHHHHHHHCCHHEECCCCCHHHHHHHH
FGVCFFGALVQIALSRCISQLRRVITPLVTGIVITLIGVSLIKVGVTDLGGGFNAPDFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PVNLALGAFVLAVIIVLNRSNTPWVRLSAIIIGLAVGSLAAWFSGKLVPQALHDLPLISV
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEE
PVPFRFGFNFDWSAFLPVALIYLISSIETVGDLTANCMLARQPISGPSYLARLKGGVLGD
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCCCCCC
GVSCMIAATFSAFPNTTFAQNNGVIQLTGVASRYVGLYIGAVLFVLGLFPHIGAIVQQIP
CHHHHHHHHHHHCCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPVLGGATLVMFGSVAAAGVRILAQSPLDRRSMLIIATSLGVGLGIAAQPALLHQLPKLV
CCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
QNLFDSAITSGGITAIVMCLLIPEGKVTAATTDAVTEPEPVEQPR
HHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]