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The map label for this gene is yfdZ [H]

Identifier: 66043735

GI number: 66043735

Start: 506590

End: 507798

Strand: Reverse

Name: yfdZ [H]

Synonym: Psyr_0468

Alternate gene names: 66043735

Gene position: 507798-506590 (Counterclockwise)

Preceding gene: 66043737

Following gene: 66043734

Centisome position: 8.33

GC content: 61.21

Gene sequence:

>1209_bases
ATGGCAGACCAAGGTTCGCCGCGCCGCTTTGCGCGCATCGATCGACTCCCCCCTTACGTGTTCAACATCACCGCCGAGCT
GAAAATGGCTGCTCGTCGTCGCGGTGAGGACATTATCGACCTGAGCATGGGCAACCCCGACGGGGCCACACCGCCGCACA
TCGTCGACAAGCTGATCACCGTCGCCCAGCGCGAAGACACCCACGGCTACTCCACCTCGCGCGGCATTCCACGCCTGCGC
CGGGCGATTTCCAACTGGTACAAGAAACGCTACGAGGTCGACATCGACCCTGAAAGCGAAGCAATCGTGACCATTGGTTC
CAAGGAAGGCCTGGCCCACCTGATGCTCGCCACACTGGACCAGGGCGACACGGTGCTGGTGCCCAACCCCAGTTACCCGA
TCCACATCTACGGTGCCGTGATTGCCGGCGCCCAGGTGCGATCGGTGCCGCTGGTGCCTGGCGTGGACTTCTTCGACGAG
CTGGAAAAAGCCATTCGCGGCTCGATTCCCAAGCCGAAGATGATGATTCTGGGCTTTCCGTCCAACCCGACTGCGCAATG
TGTGGAGCTGGACTTCTTCGAGCGCGTGGTGGCCCTGGCCAAACAGTACGACGTGCTGGTGGTGCATGACCTGGCGTACG
CCGACATCGTCTACGATGGCTGGAAAGCCCCGTCGATCATGCAGGTGCCGGGTGCCAAGGACATTGCCGTGGAGTTCTTC
ACCCTGTCCAAGAGCTACAACATGGCCGGCTGGCGGATTGGTTTCATGGTCGGCAACCCCGAACTGGTGAATGCACTGGC
GCGGATCAAGAGTTACCACGACTACGGTACCTTCACGCCACTGCAGGTGGCTGCGATTGCCGCTCTGGAAGGCGATCAGC
AATGCGTGCTCGACATTGCCGAGCAGTATCGCCAACGCCGCAACGTACTGGTCAAGGGCTTGCACGAACTGGGCTGGATG
GTCGAGAACCCCAAGGCCTCGATGTACGTCTGGGCGAAGATTCCACAGGCCTATGCGCACCTGGGTTCGCTGGAGTTCGC
CAAGAAGCTGTTGGCCGAAGCCAAGGTGTGTGTCTCGCCGGGCATCGGTTTCGGTGAGTACGGCGACGATCATGTGCGCT
TCGCCCTGATCGAGAACCAGGACCGCATCCGCCAGGCCGTTCGTGGCATCCGCAGCATGTTCAGGGCCGACGACAAGCTC
AAGTCCTGA

Upstream 100 bases:

>100_bases
ATGGACAAAAGGCTATCAGCCCATCTATCTTCCTCGGCAGGCCGCCTCATGTGGCCACGTCGCTCGGACGGTTCCGGGCG
CTTACGTACGCGAGATACTC

Downstream 100 bases:

>100_bases
GCCCCCACTGAGACACCGCGCCTGCTGACCGACTGCGCTCGGCAGGCGCGGACGCTGCAGCCGACTGCCTCCCCACACCT
GACCGACAGTCGCTTCGGCA

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MADQGSPRRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGATPPHIVDKLITVAQREDTHGYSTSRGIPRLR
RAISNWYKKRYEVDIDPESEAIVTIGSKEGLAHLMLATLDQGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVPGVDFFDE
LEKAIRGSIPKPKMMILGFPSNPTAQCVELDFFERVVALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFF
TLSKSYNMAGWRIGFMVGNPELVNALARIKSYHDYGTFTPLQVAAIAALEGDQQCVLDIAEQYRQRRNVLVKGLHELGWM
VENPKASMYVWAKIPQAYAHLGSLEFAKKLLAEAKVCVSPGIGFGEYGDDHVRFALIENQDRIRQAVRGIRSMFRADDKL
KS

Sequences:

>Translated_402_residues
MADQGSPRRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGATPPHIVDKLITVAQREDTHGYSTSRGIPRLR
RAISNWYKKRYEVDIDPESEAIVTIGSKEGLAHLMLATLDQGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVPGVDFFDE
LEKAIRGSIPKPKMMILGFPSNPTAQCVELDFFERVVALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFF
TLSKSYNMAGWRIGFMVGNPELVNALARIKSYHDYGTFTPLQVAAIAALEGDQQCVLDIAEQYRQRRNVLVKGLHELGWM
VENPKASMYVWAKIPQAYAHLGSLEFAKKLLAEAKVCVSPGIGFGEYGDDHVRFALIENQDRIRQAVRGIRSMFRADDKL
KS
>Mature_401_residues
ADQGSPRRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGATPPHIVDKLITVAQREDTHGYSTSRGIPRLRR
AISNWYKKRYEVDIDPESEAIVTIGSKEGLAHLMLATLDQGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVPGVDFFDEL
EKAIRGSIPKPKMMILGFPSNPTAQCVELDFFERVVALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFFT
LSKSYNMAGWRIGFMVGNPELVNALARIKSYHDYGTFTPLQVAAIAALEGDQQCVLDIAEQYRQRRNVLVKGLHELGWMV
ENPKASMYVWAKIPQAYAHLGSLEFAKKLLAEAKVCVSPGIGFGEYGDDHVRFALIENQDRIRQAVRGIRSMFRADDKLK
S

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=417, Percent_Identity=24.220623501199, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI56713256, Length=417, Percent_Identity=24.220623501199, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI95147551, Length=424, Percent_Identity=21.4622641509434, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI169881279, Length=424, Percent_Identity=21.4622641509434, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI169881281, Length=243, Percent_Identity=19.3415637860082, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1788722, Length=400, Percent_Identity=88.25, Blast_Score=733, Evalue=0.0,
Organism=Escherichia coli, GI1786816, Length=369, Percent_Identity=24.9322493224932, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788627, Length=377, Percent_Identity=27.0557029177719, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788332, Length=227, Percent_Identity=28.6343612334802, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=400, Percent_Identity=23.75, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=372, Percent_Identity=24.7311827956989, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=372, Percent_Identity=24.7311827956989, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320317, Length=350, Percent_Identity=24.8571428571429, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=391, Percent_Identity=20.7161125319693, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573069, Length=408, Percent_Identity=25, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646114, Length=408, Percent_Identity=25, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573067, Length=408, Percent_Identity=25, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573065, Length=408, Percent_Identity=25, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI18859735, Length=395, Percent_Identity=21.5189873417722, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44819; Mature: 44688

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQGSPRRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGATPPHIVDKLIT
CCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
VAQREDTHGYSTSRGIPRLRRAISNWYKKRYEVDIDPESEAIVTIGSKEGLAHLMLATLD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCHHHHHHHHCC
QGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVPGVDFFDELEKAIRGSIPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECC
SNPTAQCVELDFFERVVALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFF
CCCCCHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCCEEEEEE
TLSKSYNMAGWRIGFMVGNPELVNALARIKSYHDYGTFTPLQVAAIAALEGDQQCVLDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHH
EQYRQRRNVLVKGLHELGWMVENPKASMYVWAKIPQAYAHLGSLEFAKKLLAEAKVCVSP
HHHHHHHHHHHHHHHHHCCEEECCCCCEEEEEECCHHHHHHCCHHHHHHHHHHHHHHCCC
GIGFGEYGDDHVRFALIENQDRIRQAVRGIRSMFRADDKLKS
CCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure 
ADQGSPRRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGATPPHIVDKLIT
CCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
VAQREDTHGYSTSRGIPRLRRAISNWYKKRYEVDIDPESEAIVTIGSKEGLAHLMLATLD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCHHHHHHHHCC
QGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVPGVDFFDELEKAIRGSIPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECC
SNPTAQCVELDFFERVVALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFF
CCCCCHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCCEEEEEE
TLSKSYNMAGWRIGFMVGNPELVNALARIKSYHDYGTFTPLQVAAIAALEGDQQCVLDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHH
EQYRQRRNVLVKGLHELGWMVENPKASMYVWAKIPQAYAHLGSLEFAKKLLAEAKVCVSP
HHHHHHHHHHHHHHHHHCCEEECCCCCEEEEEECCHHHHHHCCHHHHHHHHHHHHHHCCC
GIGFGEYGDDHVRFALIENQDRIRQAVRGIRSMFRADDKLKS
CCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]