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The map label for this gene is fabF [H]

Identifier: 66043692

GI number: 66043692

Start: 463950

End: 465146

Strand: Reverse

Name: fabF [H]

Synonym: Psyr_0425

Alternate gene names: 66043692

Gene position: 465146-463950 (Counterclockwise)

Preceding gene: 66043693

Following gene: 66043691

Centisome position: 7.63

GC content: 65.25

Gene sequence:

>1197_bases
ATGACTGCCTATCTCAACGCGCTGGGCGTGATCTGCTCGCTGGGCGACAGCCGTGAAGAGGTGTCGCGCAGGCTGTTCGC
AGGCGACAGCTCGGGCATGGTGTTCGAAAGCGGCTGGGTGCCGGAACGTGCGTTGCCGGTCGGCGCGGTCAAATCCGCAC
TGCCGCCCATTCCGCCTGCCGTGCATTTGCATCACAGCCGCAATAACCAGCTGCTGCTGGCCGCCGCCCTGCAGATCGAG
GAGGACATCAGCCAGGCCATCACCCGCTTCGGCGCCGGGCGGATTGGCGTGATCATCGGCACCAGCACCTCGGGCATTGA
TGAAGCGAGCGAGAGCATGGCCGTCTGGCTGCGTGAGCGGACCTTCCCCGACGATTACGATTATCGGCAACAGGAACTGG
GCGCACCGGCGAATTTTCTCGCCGCCTGGCTGCAATTGAGCGGCCCGGCCTACGTCATCTCGACAGCCTGCACCTCCAGC
TCGCGGGCGTTGCTCAGTGCACGGCGGGCGCTGGACATGGGCCTGTGCGATGCCGTGCTGTGCGGCGGCGTCGACAGCCT
GTGCAGGCTGACCCTGCAGGGGTTCTCGGCACTCGAGGCCATGTCGCCGCAGCTCTGCAACCCGTTCTCCAGCAACCGCA
ACGGGATCAATATCGGCGAGGCGGCCGCGCTGTTCCTGATGACTCGTGAAGCCGACAGCAGGCACTCGATTGCCCTGCTG
GGCGCAGGTGCCAGCTGCGACGCTCACCACATCTCGGCCCCCGAACCCACCGGGCGTGGTGCGCGCGATGCCATGCTGCA
AGCGTTGCGCAATGCCCGACTCGAGGCGGAACAGATCGGTTATCTGAACCTGCATGGCACCGCCACGCCGCACAACGACG
CGATGGAGAGCCTGGCCGTGCAGGGGGTATTTCCGAACGGCGTGCCCTGCTCGTCGACCAAACCGCTCAGCGGCCACACC
CTGGGCGCGGCAGGCGCGCTGGAAGCGGCGTTTTGCTGGCTGAGCCTGGCACCGCAGAATACCGAACAGGCCCTGCCCCC
GCACTTGTGGGACGGCGAGGCCGATCCGCTCTTGCCAGCGCTGCACTGGACACATGCAGGCTCGCGCCTGACACCTGAAA
ACGCTCGTTACATGATGAGCAATTCGTTTGCCTTCGGTGGCAACAACATCAGCCTGATTATCGGAGATGCCCCATGA

Upstream 100 bases:

>100_bases
ACCGCTGGCTGGTCGAATATCAATCGGCCAACGCGTTCACTGTCCGCCTCAAGGACCGGCTGAGCTACAAGGTTACACCG
CTGAACAACGAGAGCCTGCC

Downstream 100 bases:

>100_bases
CCGAGTGGCCGCTCGCCGAACTCATCCCCCATGCCGGCGACATGATTCTCATCGATCAGGTGCTGAGCTTTGACGAAGAG
CAGATTCGAACCCGCCTGAC

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTAYLNALGVICSLGDSREEVSRRLFAGDSSGMVFESGWVPERALPVGAVKSALPPIPPAVHLHHSRNNQLLLAAALQIE
EDISQAITRFGAGRIGVIIGTSTSGIDEASESMAVWLRERTFPDDYDYRQQELGAPANFLAAWLQLSGPAYVISTACTSS
SRALLSARRALDMGLCDAVLCGGVDSLCRLTLQGFSALEAMSPQLCNPFSSNRNGINIGEAAALFLMTREADSRHSIALL
GAGASCDAHHISAPEPTGRGARDAMLQALRNARLEAEQIGYLNLHGTATPHNDAMESLAVQGVFPNGVPCSSTKPLSGHT
LGAAGALEAAFCWLSLAPQNTEQALPPHLWDGEADPLLPALHWTHAGSRLTPENARYMMSNSFAFGGNNISLIIGDAP

Sequences:

>Translated_398_residues
MTAYLNALGVICSLGDSREEVSRRLFAGDSSGMVFESGWVPERALPVGAVKSALPPIPPAVHLHHSRNNQLLLAAALQIE
EDISQAITRFGAGRIGVIIGTSTSGIDEASESMAVWLRERTFPDDYDYRQQELGAPANFLAAWLQLSGPAYVISTACTSS
SRALLSARRALDMGLCDAVLCGGVDSLCRLTLQGFSALEAMSPQLCNPFSSNRNGINIGEAAALFLMTREADSRHSIALL
GAGASCDAHHISAPEPTGRGARDAMLQALRNARLEAEQIGYLNLHGTATPHNDAMESLAVQGVFPNGVPCSSTKPLSGHT
LGAAGALEAAFCWLSLAPQNTEQALPPHLWDGEADPLLPALHWTHAGSRLTPENARYMMSNSFAFGGNNISLIIGDAP
>Mature_397_residues
TAYLNALGVICSLGDSREEVSRRLFAGDSSGMVFESGWVPERALPVGAVKSALPPIPPAVHLHHSRNNQLLLAAALQIEE
DISQAITRFGAGRIGVIIGTSTSGIDEASESMAVWLRERTFPDDYDYRQQELGAPANFLAAWLQLSGPAYVISTACTSSS
RALLSARRALDMGLCDAVLCGGVDSLCRLTLQGFSALEAMSPQLCNPFSSNRNGINIGEAAALFLMTREADSRHSIALLG
AGASCDAHHISAPEPTGRGARDAMLQALRNARLEAEQIGYLNLHGTATPHNDAMESLAVQGVFPNGVPCSSTKPLSGHTL
GAAGALEAAFCWLSLAPQNTEQALPPHLWDGEADPLLPALHWTHAGSRLTPENARYMMSNSFAFGGNNISLIIGDAP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=265, Percent_Identity=37.7358490566038, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI223972627, Length=152, Percent_Identity=40.1315789473684, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI41872631, Length=343, Percent_Identity=27.4052478134111, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1787337, Length=273, Percent_Identity=35.8974358974359, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788663, Length=271, Percent_Identity=29.8892988929889, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71983541, Length=272, Percent_Identity=33.0882352941176, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71983535, Length=262, Percent_Identity=32.824427480916, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI212642053, Length=344, Percent_Identity=24.7093023255814, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17550940, Length=194, Percent_Identity=27.319587628866, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320904, Length=337, Percent_Identity=28.7833827893175, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644341, Length=420, Percent_Identity=29.5238095238095, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI19920632, Length=315, Percent_Identity=25.0793650793651, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221330659, Length=315, Percent_Identity=25.0793650793651, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581345, Length=271, Percent_Identity=25.830258302583, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42093; Mature: 41962

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAYLNALGVICSLGDSREEVSRRLFAGDSSGMVFESGWVPERALPVGAVKSALPPIPPA
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCC
VHLHHSRNNQLLLAAALQIEEDISQAITRFGAGRIGVIIGTSTSGIDEASESMAVWLRER
EEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHC
TFPDDYDYRQQELGAPANFLAAWLQLSGPAYVISTACTSSSRALLSARRALDMGLCDAVL
CCCCCCCHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
CGGVDSLCRLTLQGFSALEAMSPQLCNPFSSNRNGINIGEAAALFLMTREADSRHSIALL
HCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHEEEEEEECCCCCCCCEEEE
GAGASCDAHHISAPEPTGRGARDAMLQALRNARLEAEQIGYLNLHGTATPHNDAMESLAV
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCEEEECCCCCCCHHHHHHHEE
QGVFPNGVPCSSTKPLSGHTLGAAGALEAAFCWLSLAPQNTEQALPPHLWDGEADPLLPA
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCHH
LHWTHAGSRLTPENARYMMSNSFAFGGNNISLIIGDAP
HHHHCCCCCCCCCCCCEEEECCEEECCCEEEEEECCCC
>Mature Secondary Structure 
TAYLNALGVICSLGDSREEVSRRLFAGDSSGMVFESGWVPERALPVGAVKSALPPIPPA
CHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCC
VHLHHSRNNQLLLAAALQIEEDISQAITRFGAGRIGVIIGTSTSGIDEASESMAVWLRER
EEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHC
TFPDDYDYRQQELGAPANFLAAWLQLSGPAYVISTACTSSSRALLSARRALDMGLCDAVL
CCCCCCCHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
CGGVDSLCRLTLQGFSALEAMSPQLCNPFSSNRNGINIGEAAALFLMTREADSRHSIALL
HCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHEEEEEEECCCCCCCCEEEE
GAGASCDAHHISAPEPTGRGARDAMLQALRNARLEAEQIGYLNLHGTATPHNDAMESLAV
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCEEEECCCCCCCHHHHHHHEE
QGVFPNGVPCSSTKPLSGHTLGAAGALEAAFCWLSLAPQNTEQALPPHLWDGEADPLLPA
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCHH
LHWTHAGSRLTPENARYMMSNSFAFGGNNISLIIGDAP
HHHHCCCCCCCCCCCCEEEECCEEECCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]