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The map label for this gene is aroB [H]

Identifier: 66043676

GI number: 66043676

Start: 439198

End: 440301

Strand: Direct

Name: aroB [H]

Synonym: Psyr_0409

Alternate gene names: 66043676

Gene position: 439198-440301 (Clockwise)

Preceding gene: 66043675

Following gene: 66043677

Centisome position: 7.21

GC content: 61.5

Gene sequence:

>1104_bases
ATGCAGACACTTAAGGTCGAGCTTGGTGAGCGTAGCTACCCGATCCATATTGGCGAAGGCCTGCTGGATCAGCCAGAGCT
CCTGACCCCGCATATCGTCGGGCGTCAGGTGGCTATCGTTTCCAACACGACAGTGGCACCGCTGTACCTGGAACGCCTGA
CGCAAACCCTGGCCGGTTACAACGTTCTGCCGATTGTTCTGCCCGATGGCGAGGCGTTCAAGAACTGGGAGACCCTGCAG
ACCATTTTCGATGGCCTGCTGACCGCCCGTCATGATCGTCGTACCACGGTCATCGCCCTGGGTGGCGGGGTGATCGGCGA
CATGGCCGGGTTCGCTGCCGCCTGCTATCAGCGTGGCGTGAACTTCATCCAGATCCCGACCACGCTGCTGTCTCAGGTGG
ACTCGTCGGTCGGCGGCAAGACCGGCATCAACCACCCGCTGGGCAAGAACATGGTCGGTGCCTTCTATCAGCCGAGTGTG
GTGCTGATCGATACCGCCTCGCTCAATACTCTGCCCGAGCGCGAGCTGTCCGCCGGGCTGGCGGAAGTCATCAAGTACGG
CCTGATCTGCGACGAACCCTTTCTGACCTGGCTCGAAGAGCACGTCGATGCACTGCGCGGGCTGGACCAGGCGGCGCTGA
CCGTGGCCATCGAACGTTCCTGCGCCGCCAAGGCGCTGGTGGTCGGCGCCGATGAGCGCGAGTCCGGTGTTCGTGCGACA
TTGAACCTGGGTCACACATTCGGGCACGCCATCGAGACGCATATGGGCTATGGTGTCTGGCTGCATGGCGAGGCGGTTGC
TGCCGGTACGGTCATGGCGCTGGAAATGTCCTCGCGCCTGGGCTGGATCAGCACGCAGGAGCGGGATCGCGGCATTCGCC
TGTTTCAGCGTGCCGGGCTGCCGGTCGTGCCGCCGCAGGACATGACGCAAGACAATTTCCTCGAACACATGGCGATCGAC
AAGAAAGTCATCGACGGTCGCTTGCGTCTGGTGCTGTTGCGCCGGATGGGTGAAGCGGTTATCACGGACGAATATCCAAA
AGAAGTATTACAGGCCACTCTGGTTGCGGATTATCGCGCCCTGGTGGATCAGCTCAGAGGTTAA

Upstream 100 bases:

>100_bases
TGCGCTATTCTCGACGCCCGGAAAACAGCGACGGTGCATGGCCTTGCGTCATGACCTGCTGAAGCACACACCGTCCAATC
GGTAATCAATGTGGGGACAC

Downstream 100 bases:

>100_bases
CGGAAACCCCATGACTAGTTTGCATGCCGACGAGGCCTTCCTCGGCCATTATCAGTTGAGTCATGACCCCTTTGCGGCGC
GGGTACCTGGCTTCAAATTC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MQTLKVELGERSYPIHIGEGLLDQPELLTPHIVGRQVAIVSNTTVAPLYLERLTQTLAGYNVLPIVLPDGEAFKNWETLQ
TIFDGLLTARHDRRTTVIALGGGVIGDMAGFAAACYQRGVNFIQIPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPSV
VLIDTASLNTLPERELSAGLAEVIKYGLICDEPFLTWLEEHVDALRGLDQAALTVAIERSCAAKALVVGADERESGVRAT
LNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSSRLGWISTQERDRGIRLFQRAGLPVVPPQDMTQDNFLEHMAID
KKVIDGRLRLVLLRRMGEAVITDEYPKEVLQATLVADYRALVDQLRG

Sequences:

>Translated_367_residues
MQTLKVELGERSYPIHIGEGLLDQPELLTPHIVGRQVAIVSNTTVAPLYLERLTQTLAGYNVLPIVLPDGEAFKNWETLQ
TIFDGLLTARHDRRTTVIALGGGVIGDMAGFAAACYQRGVNFIQIPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPSV
VLIDTASLNTLPERELSAGLAEVIKYGLICDEPFLTWLEEHVDALRGLDQAALTVAIERSCAAKALVVGADERESGVRAT
LNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSSRLGWISTQERDRGIRLFQRAGLPVVPPQDMTQDNFLEHMAID
KKVIDGRLRLVLLRRMGEAVITDEYPKEVLQATLVADYRALVDQLRG
>Mature_367_residues
MQTLKVELGERSYPIHIGEGLLDQPELLTPHIVGRQVAIVSNTTVAPLYLERLTQTLAGYNVLPIVLPDGEAFKNWETLQ
TIFDGLLTARHDRRTTVIALGGGVIGDMAGFAAACYQRGVNFIQIPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPSV
VLIDTASLNTLPERELSAGLAEVIKYGLICDEPFLTWLEEHVDALRGLDQAALTVAIERSCAAKALVVGADERESGVRAT
LNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSSRLGWISTQERDRGIRLFQRAGLPVVPPQDMTQDNFLEHMAID
KKVIDGRLRLVLLRRMGEAVITDEYPKEVLQATLVADYRALVDQLRG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=341, Percent_Identity=58.9442815249267, Blast_Score=387, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6320332, Length=369, Percent_Identity=35.230352303523, Blast_Score=193, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40025; Mature: 40025

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLKVELGERSYPIHIGEGLLDQPELLTPHIVGRQVAIVSNTTVAPLYLERLTQTLAGY
CCEEEEECCCCCCCEEECCCCCCCCCCCCCHHCCCEEEEEECCCHHHHHHHHHHHHHCCC
NVLPIVLPDGEAFKNWETLQTIFDGLLTARHDRRTTVIALGGGVIGDMAGFAAACYQRGV
CEEEEEECCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCC
NFIQIPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPSVVLIDTASLNTLPERELSAGL
CEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEEECCCCCCCCHHHHHHHH
AEVIKYGLICDEPFLTWLEEHVDALRGLDQAALTVAIERSCAAKALVVGADERESGVRAT
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCEEE
LNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSSRLGWISTQERDRGIRLFQRAGL
EECCHHHHHHHHHHCCCEEEEECCHHHHHHEEEEEHHHCCCCCCCCCHHHHHHHHHHCCC
PVVPPQDMTQDNFLEHMAIDKKVIDGRLRLVLLRRMGEAVITDEYPKEVLQATLVADYRA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHH
LVDQLRG
HHHHHCC
>Mature Secondary Structure
MQTLKVELGERSYPIHIGEGLLDQPELLTPHIVGRQVAIVSNTTVAPLYLERLTQTLAGY
CCEEEEECCCCCCCEEECCCCCCCCCCCCCHHCCCEEEEEECCCHHHHHHHHHHHHHCCC
NVLPIVLPDGEAFKNWETLQTIFDGLLTARHDRRTTVIALGGGVIGDMAGFAAACYQRGV
CEEEEEECCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCC
NFIQIPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPSVVLIDTASLNTLPERELSAGL
CEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEEECCCCCCCCHHHHHHHH
AEVIKYGLICDEPFLTWLEEHVDALRGLDQAALTVAIERSCAAKALVVGADERESGVRAT
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCEEE
LNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSSRLGWISTQERDRGIRLFQRAGL
EECCHHHHHHHHHHCCCEEEEECCHHHHHHEEEEEHHHCCCCCCCCCHHHHHHHHHHCCC
PVVPPQDMTQDNFLEHMAIDKKVIDGRLRLVLLRRMGEAVITDEYPKEVLQATLVADYRA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHH
LVDQLRG
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA