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The map label for this gene is glpT [H]

Identifier: 66043575

GI number: 66043575

Start: 325019

End: 326368

Strand: Reverse

Name: glpT [H]

Synonym: Psyr_0305

Alternate gene names: 66043575

Gene position: 326368-325019 (Counterclockwise)

Preceding gene: 66043577

Following gene: 66043568

Centisome position: 5.36

GC content: 61.19

Gene sequence:

>1350_bases
ATGTTTGGGTTTTTCCGTCCTGCCAGGCATCAGGCACCCCTTCCCGAAGAAAAGGTCGACAGCACCTATCGGCGTCTGCG
CTGGCAGATCTTCGCAGGCATCTTTATCGGCTATGCGGGTTACTACCTGCTGCGCAAGAATTTCTCGCTGGCGATGCCGT
ATCTGATCGACGAAGGCTATACGCGTGGCCAGCTGGGCGTGGCGATGTCTGCCATTGCCATTGCCTACGGCTTGTCGAAA
TTCCTCATGGGCATCGTTTCGGATCGCTCCAACCCGCGTTACTTCCTGCCGTTCGGCCTGCTGGTCTCTGCCGGGATCAT
GTTCATCTTCGGCTTCGCGCCGTGGGCGACGTCCAGTGTCACGATCATGTTCGTGCTGCTGTTCATCAATGGCTGGGCAC
AGGGCATGGGCTGGCCGCCGAGCGGGCGGACAATGGTTCACTGGTGGTCGCAGAAAGAGCGCGGCGGTGTGGTGTCGGTG
TGGAACGTGGCGCACAACGTCGGCGGCGGCCTGATCGGCCCGCTGTTCCTGCTCGGCATGGGCTGGACCAACGACTGGCA
TGCGGCGTTCTACGTGCCGGCGGCGGTTGCGTTGCTGGTCGCGGTGTTCGCCTTCGCGACCATGCGTGACACCCCGCAAT
CGGTCGGCCTGCCGCCTATCGAGCACTACAAGAACGATTACCCGGAAGGCTACGATGCCAGCCACGAGGAAGAATTCAGC
GCCCGGGAGATCTTCGTCAAGTACGTGCTGCGCAACAAGTTCCTGTGGTACATCGCCATGGCCAACGTGTTCGTTTATCT
GCTGCGCTATGGCGTACTGGACTGGGCACCGACCTATCTCAAGGAAGCCAAACACTTCACGGTCGACAAGACCTCCTGGG
CTTACTTTCTGTACGAGTGGGCGGGCATTCCGGGCACGCTGCTGTGCGGCTGGATGTCGGACAAGATCTTCAAGGGCAAT
CGCGGCCTGACCGGCATGGTGTTCATGTTTCTGGTGACCATCGCCACGCTGGTGTACTGGCTGAACCCTGAAGGCAATCC
GACCGTCGACATGATCGCGCTGGTGTCCATCGGTTTCCTGATCTACGGACCGGTGATGCTGATCGGCCTGCAGGCGCTGG
AACTGGCACCGAAGAAGGCAGCAGGCACGGCCGCCGGCTTTACCGGGCTGTTCGGCTATCTGGGCGGGTCGGTCGCGGCC
AGCGCAGCGATGGGCTACACGGTTGACCACTTCGGCTGGGATGGCGGCTTCGTGCTGTTGATCGGCGCGTGCATTCTGGC
GATGGTGTTCCTTGCGCCGACGCTGCGGCACAAACAGGTCGCCAGCACATCTCGCGACACCAAAGGCTGA

Upstream 100 bases:

>100_bases
TGCATTTCCTACAAAGAATCAGCCCGAAGGCACTGCTTTTTTCTGTAATGAAAATGTAATATTCGCATTCGCAAAAACAA
CAATAATCAGGAGCTTCTCC

Downstream 100 bases:

>100_bases
TCAGGCAGTCTCTGACTTGCAGCGCTTGAGCCGCGCCTCCAGATTCAGGTCTGGCATGGCGTGGCTACGCAGGGCCTTGG
CGGTCTGCTCGACGTACTCG

Product: sn-glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MFGFFRPARHQAPLPEEKVDSTYRRLRWQIFAGIFIGYAGYYLLRKNFSLAMPYLIDEGYTRGQLGVAMSAIAIAYGLSK
FLMGIVSDRSNPRYFLPFGLLVSAGIMFIFGFAPWATSSVTIMFVLLFINGWAQGMGWPPSGRTMVHWWSQKERGGVVSV
WNVAHNVGGGLIGPLFLLGMGWTNDWHAAFYVPAAVALLVAVFAFATMRDTPQSVGLPPIEHYKNDYPEGYDASHEEEFS
AREIFVKYVLRNKFLWYIAMANVFVYLLRYGVLDWAPTYLKEAKHFTVDKTSWAYFLYEWAGIPGTLLCGWMSDKIFKGN
RGLTGMVFMFLVTIATLVYWLNPEGNPTVDMIALVSIGFLIYGPVMLIGLQALELAPKKAAGTAAGFTGLFGYLGGSVAA
SAAMGYTVDHFGWDGGFVLLIGACILAMVFLAPTLRHKQVASTSRDTKG

Sequences:

>Translated_449_residues
MFGFFRPARHQAPLPEEKVDSTYRRLRWQIFAGIFIGYAGYYLLRKNFSLAMPYLIDEGYTRGQLGVAMSAIAIAYGLSK
FLMGIVSDRSNPRYFLPFGLLVSAGIMFIFGFAPWATSSVTIMFVLLFINGWAQGMGWPPSGRTMVHWWSQKERGGVVSV
WNVAHNVGGGLIGPLFLLGMGWTNDWHAAFYVPAAVALLVAVFAFATMRDTPQSVGLPPIEHYKNDYPEGYDASHEEEFS
AREIFVKYVLRNKFLWYIAMANVFVYLLRYGVLDWAPTYLKEAKHFTVDKTSWAYFLYEWAGIPGTLLCGWMSDKIFKGN
RGLTGMVFMFLVTIATLVYWLNPEGNPTVDMIALVSIGFLIYGPVMLIGLQALELAPKKAAGTAAGFTGLFGYLGGSVAA
SAAMGYTVDHFGWDGGFVLLIGACILAMVFLAPTLRHKQVASTSRDTKG
>Mature_449_residues
MFGFFRPARHQAPLPEEKVDSTYRRLRWQIFAGIFIGYAGYYLLRKNFSLAMPYLIDEGYTRGQLGVAMSAIAIAYGLSK
FLMGIVSDRSNPRYFLPFGLLVSAGIMFIFGFAPWATSSVTIMFVLLFINGWAQGMGWPPSGRTMVHWWSQKERGGVVSV
WNVAHNVGGGLIGPLFLLGMGWTNDWHAAFYVPAAVALLVAVFAFATMRDTPQSVGLPPIEHYKNDYPEGYDASHEEEFS
AREIFVKYVLRNKFLWYIAMANVFVYLLRYGVLDWAPTYLKEAKHFTVDKTSWAYFLYEWAGIPGTLLCGWMSDKIFKGN
RGLTGMVFMFLVTIATLVYWLNPEGNPTVDMIALVSIGFLIYGPVMLIGLQALELAPKKAAGTAAGFTGLFGYLGGSVAA
SAAMGYTVDHFGWDGGFVLLIGACILAMVFLAPTLRHKQVASTSRDTKG

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=437, Percent_Identity=28.604118993135, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI4503847, Length=437, Percent_Identity=28.604118993135, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI256219483, Length=437, Percent_Identity=28.604118993135, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI256219543, Length=451, Percent_Identity=28.3813747228381, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI256219564, Length=368, Percent_Identity=26.3586956521739, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI223717983, Length=413, Percent_Identity=24.9394673123487, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI38093649, Length=415, Percent_Identity=24.8192771084337, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI46361976, Length=405, Percent_Identity=24.9382716049383, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI49619231, Length=439, Percent_Identity=22.5512528473804, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI14150047, Length=251, Percent_Identity=27.0916334661355, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1788573, Length=445, Percent_Identity=72.1348314606741, Blast_Score=682, Evalue=0.0,
Organism=Escherichia coli, GI87082310, Length=445, Percent_Identity=35.9550561797753, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI2367259, Length=449, Percent_Identity=32.293986636971, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789515, Length=432, Percent_Identity=22.2222222222222, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082320, Length=412, Percent_Identity=24.5145631067961, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367379, Length=359, Percent_Identity=23.6768802228412, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789152, Length=438, Percent_Identity=21.0045662100457, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI133901854, Length=446, Percent_Identity=25.5605381165919, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI133901856, Length=446, Percent_Identity=25.5605381165919, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI133930953, Length=479, Percent_Identity=21.0855949895616, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564202, Length=439, Percent_Identity=25.5125284738041, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564204, Length=370, Percent_Identity=26.7567567567568, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17542316, Length=453, Percent_Identity=21.6335540838852, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17539138, Length=327, Percent_Identity=23.2415902140673, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24656861, Length=481, Percent_Identity=23.4927234927235, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24656866, Length=481, Percent_Identity=23.4927234927235, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI45550478, Length=481, Percent_Identity=23.4927234927235, Blast_Score=99, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49832; Mature: 49832

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3329281; 9205837; 9278503; 3141744; 12893936 [H]