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The map label for this gene is thrB [H]

Identifier: 66043542

GI number: 66043542

Start: 290854

End: 291804

Strand: Direct

Name: thrB [H]

Synonym: Psyr_0272

Alternate gene names: 66043542

Gene position: 290854-291804 (Clockwise)

Preceding gene: 66043541

Following gene: 66043546

Centisome position: 4.77

GC content: 61.3

Gene sequence:

>951_bases
ATGTCCGTTTTTACCCCACTGGCTCGGCCCGAGCTGGAAACATTTCTCGCCCCTTACGGGCTCGGCCGTCTGCTTGACTA
TCAGGGCATCGCTGCCGGTAGTGAAAACACCAATTACTTCATCAGTCTGGAGCAGGGCGAGTTCGTGCTGACTTTGGTCG
AGCGCGGCCCGGTTCAGGAGATGCCGTTCTTCATCGAGCTGCTCGACGTGCTGCATGAAGCCGATCTGCCGGTGCCTTAT
GCGCTGCGCACCACCGACGGTCAGGCGCTGCGCGAGCTGGCAGACAAGCCGGCGCTTTTGCAGCCGCGTCTGCCGGGCAA
GCACATCAGTGAGCCGAACACCCAGCACTGCGTGCAGATTGGCGAGTTGCTGGCCAACCTGCATCTGGCGACCCGCGGGC
AGATCGTCGAGCGCAAGACTGATCGCGGTCTGGACTGGATGCTGAGCGAGGGGCGCAATTTTCTGTCGCACCTGGGCGAG
ACGCAGCGAGCGCTGCTTGAAAAGAGCCTTCAGGAGATCGAGGCGTGCAAACCGCAGATCATGGCGCTGCCGCGCGCCAA
TCTGCATGCCGATCTGTTCCGCGACAACGTACTGTTCGAAGGGACGCACCTGACCGGGTTGATCGATTTCTACAATGCCT
GCTCGGGTCCGATGTTGTACGACCTGGCGATTACCCTCAACGACTGGTGTTCCCGCGAAAACGGTCAGCTCGATGCTGTC
CGCGCGCGCGCCTTGCTGGGGGCCTATGCAGGCTTGCGACCGTTCACGGCTGCGGAGTCGAAGCTCTGGGCGACCATGTT
GCGTATCGCTTGTGTGCGTTTCTGGCTGTCACGTTTGATCGCCGCTGAAACCTTCGCCGGTCAGGATGTGCTGATTCATG
ATCCTGCGGAGTTCGAGCGCCGCCTGGCCGAGCGCCAGGAAGCGCATATTGCGTTGCCGTTTGCGCTCTGA

Upstream 100 bases:

>100_bases
CAATTTCATTCGTTCGGACCAACCGGACATGCTGATCCCGCAGTGGGAAATATTCAGCTGGTAGCACCCTACATTCACTT
CAATCGTTGGCAGTCCTGAT

Downstream 100 bases:

>100_bases
GACCAGACCTGTCTTCGCGAGTCTGAACTAGTCGGACGGTTGACTCTCGTTCCCATGCTCTGGTGTGACCCCCGAAGGTT
GGACAATTATCCACCTACGC

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSVFTPLARPELETFLAPYGLGRLLDYQGIAAGSENTNYFISLEQGEFVLTLVERGPVQEMPFFIELLDVLHEADLPVPY
ALRTTDGQALRELADKPALLQPRLPGKHISEPNTQHCVQIGELLANLHLATRGQIVERKTDRGLDWMLSEGRNFLSHLGE
TQRALLEKSLQEIEACKPQIMALPRANLHADLFRDNVLFEGTHLTGLIDFYNACSGPMLYDLAITLNDWCSRENGQLDAV
RARALLGAYAGLRPFTAAESKLWATMLRIACVRFWLSRLIAAETFAGQDVLIHDPAEFERRLAERQEAHIALPFAL

Sequences:

>Translated_316_residues
MSVFTPLARPELETFLAPYGLGRLLDYQGIAAGSENTNYFISLEQGEFVLTLVERGPVQEMPFFIELLDVLHEADLPVPY
ALRTTDGQALRELADKPALLQPRLPGKHISEPNTQHCVQIGELLANLHLATRGQIVERKTDRGLDWMLSEGRNFLSHLGE
TQRALLEKSLQEIEACKPQIMALPRANLHADLFRDNVLFEGTHLTGLIDFYNACSGPMLYDLAITLNDWCSRENGQLDAV
RARALLGAYAGLRPFTAAESKLWATMLRIACVRFWLSRLIAAETFAGQDVLIHDPAEFERRLAERQEAHIALPFAL
>Mature_315_residues
SVFTPLARPELETFLAPYGLGRLLDYQGIAAGSENTNYFISLEQGEFVLTLVERGPVQEMPFFIELLDVLHEADLPVPYA
LRTTDGQALRELADKPALLQPRLPGKHISEPNTQHCVQIGELLANLHLATRGQIVERKTDRGLDWMLSEGRNFLSHLGET
QRALLEKSLQEIEACKPQIMALPRANLHADLFRDNVLFEGTHLTGLIDFYNACSGPMLYDLAITLNDWCSRENGQLDAVR
ARALLGAYAGLRPFTAAESKLWATMLRIACVRFWLSRLIAAETFAGQDVLIHDPAEFERRLAERQEAHIALPFAL

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 35430; Mature: 35299

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFTPLARPELETFLAPYGLGRLLDYQGIAAGSENTNYFISLEQGEFVLTLVERGPVQE
CCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCHH
MPFFIELLDVLHEADLPVPYALRTTDGQALRELADKPALLQPRLPGKHISEPNTQHCVQI
CHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHH
GELLANLHLATRGQIVERKTDRGLDWMLSEGRNFLSHLGETQRALLEKSLQEIEACKPQI
HHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHH
MALPRANLHADLFRDNVLFEGTHLTGLIDFYNACSGPMLYDLAITLNDWCSRENGQLDAV
EECCCCCCHHHHHHCCEEEECCHHHHHHHHHHCCCCCEEEEEEEEHHHHCCCCCCCHHHH
RARALLGAYAGLRPFTAAESKLWATMLRIACVRFWLSRLIAAETFAGQDVLIHDPAEFER
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
RLAERQEAHIALPFAL
HHHHHHHCEEEECCCC
>Mature Secondary Structure 
SVFTPLARPELETFLAPYGLGRLLDYQGIAAGSENTNYFISLEQGEFVLTLVERGPVQE
CCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCHH
MPFFIELLDVLHEADLPVPYALRTTDGQALRELADKPALLQPRLPGKHISEPNTQHCVQI
CHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHH
GELLANLHLATRGQIVERKTDRGLDWMLSEGRNFLSHLGETQRALLEKSLQEIEACKPQI
HHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHH
MALPRANLHADLFRDNVLFEGTHLTGLIDFYNACSGPMLYDLAITLNDWCSRENGQLDAV
EECCCCCCHHHHHHCCEEEECCHHHHHHHHHHCCCCCEEEEEEEEHHHHCCCCCCCHHHH
RARALLGAYAGLRPFTAAESKLWATMLRIACVRFWLSRLIAAETFAGQDVLIHDPAEFER
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
RLAERQEAHIALPFAL
HHHHHHHCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA