Click here to switch to the map view.

The map label for this gene is xcpR [H]

Identifier: 66043519

GI number: 66043519

Start: 261709

End: 263493

Strand: Reverse

Name: xcpR [H]

Synonym: Psyr_0249

Alternate gene names: 66043519

Gene position: 263493-261709 (Counterclockwise)

Preceding gene: 66043520

Following gene: 66043518

Centisome position: 4.32

GC content: 61.29

Gene sequence:

>1785_bases
ATGGCAGCCCTGGCCCCCTCTTCACAGGATCGCTGGCTCGATCTGAATGATGTGTTGCGTGATCTGGTTGCCGAAGGCTA
TCTCGGCCAGGACGACGCGGAAACGGCACTCACCCAACGTCGCAGTGCGGTGAACATTCAGCTGCACCCCCTCGAGTTTC
TCGCTTCGCTGCAGTTTGACGATTTCAAGCGGCCGGGCAAGAAGCTGGACGTGGAAACCCTGACCGCCTGGCTGGCCAAA
GCCTGTGGCCAGCCTTACATGCGTATCGACCCGCTGAAGATCAACGTCGCGGCGGTCACGCCACTGATGTCCTACGCCTT
TGCCCAGCGCCACAAGATTCTGGCCGTGGCGGTCGATCGCGAATCGGTGACCATCGCCAGCGCGCAGCCGTATGTGCGCT
CATGGGAAGCCGACCTGGCGCATGTGCTCAAACTGCAGATCAAACGTGTGGTCGCCAACCCGGCAGACATCCAGCGCATG
GCGATGGAGTTTTTCAGGCTGGCCAAGTCGGTCAGCGGCGCCAGCGCCTCCGAGCAAAAAATGAGCAACATGGGCAACTT
CGAACAGTTGCTCAAGCTCGGTGCCAGCGATCAGGAGCCTGACGCCAACGACGCGCACATCGTCAATATCGTCGACTGGC
TGTTCCAGTACGCCTTCCAGCAACGCGCCAGTGATATTCACATCGAGCCGCGCCGCGAACAGGGCACCGTGCGCTTTCGC
ATCGACGGGGTGCTGCACAACGTTTACCAGTTTCCGGCGCAGGTGATCATGGCGATTGTCAGCCGACTGAAAAGCCTGGG
CCGGATGAACGTCGCCGAAAAACGCAAACCACAGGACGGGCGGGTCAAGACCACCACGCCTGAGAATCGCGAAGTGGAGT
TGCGCCTGTCGACCCTGCCGACCGCGTTCGGCGAAAAAATGGTCATGCGGATCTTCGACCCCGAGGTATTGCTCAAGGAC
TTCGACCAACTGGGCTTTTCCAGTGACGACCTGCGGCGCTGGCAGGAAATGACCCGCCAGCCCAACGGCATTATTCTGGT
TACCGGTCCGACCGGTTCAGGCAAGACCACCACGCTGTACACCACCCTCAAGAAGCTGGCGACCTCCGAGGTCAACCTGT
GCACCATCGAAGATCCCATCGAGATGGTCGAACCGGCCTTCAACCAGATGCAGGTTCAACACAACATCGACCTGAGCTTT
GCCGCCGGCGTGCGCGCACTGATGCGACAGGACCCGGATATCATCATGATCGGCGAGATTCGCGACCTGGAGACCGCTGA
AATGGCGATTCAGGCGGCACTCACCGGCCACCTGGTGCTGTCGACGCTGCACACCAACGATGCGCCCAGCGCAATCAGCC
GCATGCTCGAACTGGGTGTACCGCATTACCTGCTCAAGGCCACCATCCTCGGCGTCATGGCCCAGCGTCTGGTGCGCACC
CTGTGCCCACACTGCAAGGCGCCCATCAACCTCAACGAGACCGACTGGCAAACCCTGACGCGCCCCTGGCAGGCACCGGT
GCCGCCTGGCGCGCATCAGGCGGTCGGCTGCGTGGAGTGTCGCGATACCGGCTACCGTGGCCGGGCGGGTGTTTACGAGA
TCATGGTCATGTCCGACAACATCAAGGCATTGATCTCGGCGGACCTGGACCTGACTGCCATGCGTCGTCAGGCCTTCAAG
GAAGGAACGCGCAGCCTGCGTCTGTCCGGCGCGCAGAAAGTCTCGGCAGGCCTGACTACACTCGAGGAAGTGCTGCGAGT
GACACCGCAGAGCGAACAACGCTGA

Upstream 100 bases:

>100_bases
CTGCTCCGGCAATTCCCGGTCGCATAGAACCCATAACGCTGTCACGCTTGGCGTCTACTCTTGTTCATCGTCCAATGACG
AATTGCCTCAAGGAGCGCAC

Downstream 100 bases:

>100_bases
TCAGGGTTGAAAGCGTCGTTCCAGAAGGCCTGGCGGCATGCCGAGCCAGCTAAAGTGAACTGCGCGGTACACCTTGATTG
AACTAGTTCATGCCTTTAGC

Product: type II secretion system protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MAALAPSSQDRWLDLNDVLRDLVAEGYLGQDDAETALTQRRSAVNIQLHPLEFLASLQFDDFKRPGKKLDVETLTAWLAK
ACGQPYMRIDPLKINVAAVTPLMSYAFAQRHKILAVAVDRESVTIASAQPYVRSWEADLAHVLKLQIKRVVANPADIQRM
AMEFFRLAKSVSGASASEQKMSNMGNFEQLLKLGASDQEPDANDAHIVNIVDWLFQYAFQQRASDIHIEPRREQGTVRFR
IDGVLHNVYQFPAQVIMAIVSRLKSLGRMNVAEKRKPQDGRVKTTTPENREVELRLSTLPTAFGEKMVMRIFDPEVLLKD
FDQLGFSSDDLRRWQEMTRQPNGIILVTGPTGSGKTTTLYTTLKKLATSEVNLCTIEDPIEMVEPAFNQMQVQHNIDLSF
AAGVRALMRQDPDIIMIGEIRDLETAEMAIQAALTGHLVLSTLHTNDAPSAISRMLELGVPHYLLKATILGVMAQRLVRT
LCPHCKAPINLNETDWQTLTRPWQAPVPPGAHQAVGCVECRDTGYRGRAGVYEIMVMSDNIKALISADLDLTAMRRQAFK
EGTRSLRLSGAQKVSAGLTTLEEVLRVTPQSEQR

Sequences:

>Translated_594_residues
MAALAPSSQDRWLDLNDVLRDLVAEGYLGQDDAETALTQRRSAVNIQLHPLEFLASLQFDDFKRPGKKLDVETLTAWLAK
ACGQPYMRIDPLKINVAAVTPLMSYAFAQRHKILAVAVDRESVTIASAQPYVRSWEADLAHVLKLQIKRVVANPADIQRM
AMEFFRLAKSVSGASASEQKMSNMGNFEQLLKLGASDQEPDANDAHIVNIVDWLFQYAFQQRASDIHIEPRREQGTVRFR
IDGVLHNVYQFPAQVIMAIVSRLKSLGRMNVAEKRKPQDGRVKTTTPENREVELRLSTLPTAFGEKMVMRIFDPEVLLKD
FDQLGFSSDDLRRWQEMTRQPNGIILVTGPTGSGKTTTLYTTLKKLATSEVNLCTIEDPIEMVEPAFNQMQVQHNIDLSF
AAGVRALMRQDPDIIMIGEIRDLETAEMAIQAALTGHLVLSTLHTNDAPSAISRMLELGVPHYLLKATILGVMAQRLVRT
LCPHCKAPINLNETDWQTLTRPWQAPVPPGAHQAVGCVECRDTGYRGRAGVYEIMVMSDNIKALISADLDLTAMRRQAFK
EGTRSLRLSGAQKVSAGLTTLEEVLRVTPQSEQR
>Mature_593_residues
AALAPSSQDRWLDLNDVLRDLVAEGYLGQDDAETALTQRRSAVNIQLHPLEFLASLQFDDFKRPGKKLDVETLTAWLAKA
CGQPYMRIDPLKINVAAVTPLMSYAFAQRHKILAVAVDRESVTIASAQPYVRSWEADLAHVLKLQIKRVVANPADIQRMA
MEFFRLAKSVSGASASEQKMSNMGNFEQLLKLGASDQEPDANDAHIVNIVDWLFQYAFQQRASDIHIEPRREQGTVRFRI
DGVLHNVYQFPAQVIMAIVSRLKSLGRMNVAEKRKPQDGRVKTTTPENREVELRLSTLPTAFGEKMVMRIFDPEVLLKDF
DQLGFSSDDLRRWQEMTRQPNGIILVTGPTGSGKTTTLYTTLKKLATSEVNLCTIEDPIEMVEPAFNQMQVQHNIDLSFA
AGVRALMRQDPDIIMIGEIRDLETAEMAIQAALTGHLVLSTLHTNDAPSAISRMLELGVPHYLLKATILGVMAQRLVRTL
CPHCKAPINLNETDWQTLTRPWQAPVPPGAHQAVGCVECRDTGYRGRAGVYEIMVMSDNIKALISADLDLTAMRRQAFKE
GTRSLRLSGAQKVSAGLTTLEEVLRVTPQSEQR

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=383, Percent_Identity=42.0365535248042, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI1786296, Length=377, Percent_Identity=44.2970822281167, Blast_Score=319, Evalue=4e-88,
Organism=Escherichia coli, GI87082188, Length=126, Percent_Identity=45.2380952380952, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 66321; Mature: 66190

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALAPSSQDRWLDLNDVLRDLVAEGYLGQDDAETALTQRRSAVNIQLHPLEFLASLQFD
CCCCCCCCCCCEECHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEEEEEHHHHHHHCCCH
DFKRPGKKLDVETLTAWLAKACGQPYMRIDPLKINVAAVTPLMSYAFAQRHKILAVAVDR
HHCCCCCCCCHHHHHHHHHHHCCCCCEEECCEEEEHHHHHHHHHHHHHHCCEEEEEEECC
ESVTIASAQPYVRSWEADLAHVLKLQIKRVVANPADIQRMAMEFFRLAKSVSGASASEQK
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
MSNMGNFEQLLKLGASDQEPDANDAHIVNIVDWLFQYAFQQRASDIHIEPRREQGTVRFR
HHCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEE
IDGVLHNVYQFPAQVIMAIVSRLKSLGRMNVAEKRKPQDGRVKTTTPENREVELRLSTLP
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEECCCCCCCEEEEEEECCC
TAFGEKMVMRIFDPEVLLKDFDQLGFSSDDLRRWQEMTRQPNGIILVTGPTGSGKTTTLY
CHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHH
TTLKKLATSEVNLCTIEDPIEMVEPAFNQMQVQHNIDLSFAAGVRALMRQDPDIIMIGEI
HHHHHHHCCCCCEEEECCCHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHCCCCEEEECCC
RDLETAEMAIQAALTGHLVLSTLHTNDAPSAISRMLELGVPHYLLKATILGVMAQRLVRT
CCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LCPHCKAPINLNETDWQTLTRPWQAPVPPGAHQAVGCVECRDTGYRGRAGVYEIMVMSDN
HCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCC
IKALISADLDLTAMRRQAFKEGTRSLRLSGAQKVSAGLTTLEEVLRVTPQSEQR
CCEEHCCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AALAPSSQDRWLDLNDVLRDLVAEGYLGQDDAETALTQRRSAVNIQLHPLEFLASLQFD
CCCCCCCCCCEECHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEEEEEHHHHHHHCCCH
DFKRPGKKLDVETLTAWLAKACGQPYMRIDPLKINVAAVTPLMSYAFAQRHKILAVAVDR
HHCCCCCCCCHHHHHHHHHHHCCCCCEEECCEEEEHHHHHHHHHHHHHHCCEEEEEEECC
ESVTIASAQPYVRSWEADLAHVLKLQIKRVVANPADIQRMAMEFFRLAKSVSGASASEQK
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
MSNMGNFEQLLKLGASDQEPDANDAHIVNIVDWLFQYAFQQRASDIHIEPRREQGTVRFR
HHCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEE
IDGVLHNVYQFPAQVIMAIVSRLKSLGRMNVAEKRKPQDGRVKTTTPENREVELRLSTLP
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEECCCCCCCEEEEEEECCC
TAFGEKMVMRIFDPEVLLKDFDQLGFSSDDLRRWQEMTRQPNGIILVTGPTGSGKTTTLY
CHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHH
TTLKKLATSEVNLCTIEDPIEMVEPAFNQMQVQHNIDLSFAAGVRALMRQDPDIIMIGEI
HHHHHHHCCCCCEEEECCCHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHCCCCEEEECCC
RDLETAEMAIQAALTGHLVLSTLHTNDAPSAISRMLELGVPHYLLKATILGVMAQRLVRT
CCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LCPHCKAPINLNETDWQTLTRPWQAPVPPGAHQAVGCVECRDTGYRGRAGVYEIMVMSDN
HCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCC
IKALISADLDLTAMRRQAFKEGTRSLRLSGAQKVSAGLTTLEEVLRVTPQSEQR
CCEEHCCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1588814; 10984043 [H]