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The map label for this gene is exbB [H]

Identifier: 66043475

GI number: 66043475

Start: 219735

End: 220697

Strand: Reverse

Name: exbB [H]

Synonym: Psyr_0205

Alternate gene names: 66043475

Gene position: 220697-219735 (Counterclockwise)

Preceding gene: 66043477

Following gene: 66043474

Centisome position: 3.62

GC content: 63.45

Gene sequence:

>963_bases
ATGAAACGCATTCAATCAATCGCTTCGCCTACCCAGATGCCTCGCCTGCCGCGTGCATGGCGCAGTATCGCAGCCCTTGT
CTTGAGCCTGATGTTCGTCCCCATGGCGCTCGCGGACCAATCGGCTCCGACCGCTGCCCCTGCGACTTCCACAGCACCTG
CATCACCTGCGGCAACGGCACCTGCCGCACCTGACGCAGCAGCCCCGGTGCAGGCCATGGAGCCCGCCACCGAAGACAAC
AGCCTGGGCATGGCGCATGACCTGTCGCCGTGGGGCATGTATCAGAATGCCGACGTCGTGGTCAAAGCGGTGATGATCGG
TCTGGCCATCGCCTCGATCATGACGTGGACCATCTGGATCTCCAAGGGTTTCGAGCTGCTGGGTGCCAAGCGCCGGTTGC
GCGGCGAAATTGCCAATCTGAAAAAAGCCCGCTCCCTGACTGAAGCGAGCGCCACGGCCAGCACGGAAGGCACCCTTGCC
CACCTGCTGGTGCATGACGCCCTCGAAGAGATGCGCCTGTCGGCCAACAGCCGTGAGCGCGAAGGGATCAAGGAGCGTGT
CAGCTTCCGTCTCGAGCGTCTGGTCGCCGCCTGTGGCCGCAACATGAGCATGGGCACCGGCGTGCTGGCGACCATCGGTT
CGACTGCGCCGTTCGTGGGTCTGTTCGGTACGGTCTGGGGCATCATGAACAGCTTCATCGGCATCGCCAAGACCCAGACC
ACCAACCTCGCCGTAGTCGCACCCGGCATCGCCGAAGCCCTTTTGGCCACCGCGCTGGGCCTGGTCGCGGCGATCCCTGC
GGTAGTGATCTACAACGTCTTCGCCCGCTCCATCGCCGGTTACAAGGCTCAGGTCTCCGATGCCTCGGCACACGTCCTGC
TGCTGGTCAGCCGCGATCTGGATCATCTGCCAGAGCCGTCCGAGCGCAATCAACAACAACCGCACATGGTCAAGGTGGGC
TAA

Upstream 100 bases:

>100_bases
ACGATTTGCAATAATGGCGGCCCATTCGTTCCGCGTAGCGTCGACAGCACCGAGCGACGCACTGGAACCATCCCCTTTTT
TCCTCTCAGGTCCGGCCAGC

Downstream 100 bases:

>100_bases
AACGTGGGCCTGCATCTTAACGAAGGCGGCGACGATCTCGCCGAGAACCATGAAATCAACGTGACGCCGTTCATCGACGT
CATGCTGGTGCTGCTGATCA

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKRIQSIASPTQMPRLPRAWRSIAALVLSLMFVPMALADQSAPTAAPATSTAPASPAATAPAAPDAAAPVQAMEPATEDN
SLGMAHDLSPWGMYQNADVVVKAVMIGLAIASIMTWTIWISKGFELLGAKRRLRGEIANLKKARSLTEASATASTEGTLA
HLLVHDALEEMRLSANSREREGIKERVSFRLERLVAACGRNMSMGTGVLATIGSTAPFVGLFGTVWGIMNSFIGIAKTQT
TNLAVVAPGIAEALLATALGLVAAIPAVVIYNVFARSIAGYKAQVSDASAHVLLLVSRDLDHLPEPSERNQQQPHMVKVG

Sequences:

>Translated_320_residues
MKRIQSIASPTQMPRLPRAWRSIAALVLSLMFVPMALADQSAPTAAPATSTAPASPAATAPAAPDAAAPVQAMEPATEDN
SLGMAHDLSPWGMYQNADVVVKAVMIGLAIASIMTWTIWISKGFELLGAKRRLRGEIANLKKARSLTEASATASTEGTLA
HLLVHDALEEMRLSANSREREGIKERVSFRLERLVAACGRNMSMGTGVLATIGSTAPFVGLFGTVWGIMNSFIGIAKTQT
TNLAVVAPGIAEALLATALGLVAAIPAVVIYNVFARSIAGYKAQVSDASAHVLLLVSRDLDHLPEPSERNQQQPHMVKVG
>Mature_320_residues
MKRIQSIASPTQMPRLPRAWRSIAALVLSLMFVPMALADQSAPTAAPATSTAPASPAATAPAAPDAAAPVQAMEPATEDN
SLGMAHDLSPWGMYQNADVVVKAVMIGLAIASIMTWTIWISKGFELLGAKRRLRGEIANLKKARSLTEASATASTEGTLA
HLLVHDALEEMRLSANSREREGIKERVSFRLERLVAACGRNMSMGTGVLATIGSTAPFVGLFGTVWGIMNSFIGIAKTQT
TNLAVVAPGIAEALLATALGLVAAIPAVVIYNVFARSIAGYKAQVSDASAHVLLLVSRDLDHLPEPSERNQQQPHMVKVG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=220, Percent_Identity=65.9090909090909, Blast_Score=284, Evalue=5e-78,
Organism=Escherichia coli, GI1786958, Length=211, Percent_Identity=32.2274881516588, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 33738; Mature: 33738

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIQSIASPTQMPRLPRAWRSIAALVLSLMFVPMALADQSAPTAAPATSTAPASPAATA
CCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PAAPDAAAPVQAMEPATEDNSLGMAHDLSPWGMYQNADVVVKAVMIGLAIASIMTWTIWI
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKGFELLGAKRRLRGEIANLKKARSLTEASATASTEGTLAHLLVHDALEEMRLSANSRER
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
EGIKERVSFRLERLVAACGRNMSMGTGVLATIGSTAPFVGLFGTVWGIMNSFIGIAKTQT
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
TNLAVVAPGIAEALLATALGLVAAIPAVVIYNVFARSIAGYKAQVSDASAHVLLLVSRDL
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEEECCH
DHLPEPSERNQQQPHMVKVG
HCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure
MKRIQSIASPTQMPRLPRAWRSIAALVLSLMFVPMALADQSAPTAAPATSTAPASPAATA
CCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PAAPDAAAPVQAMEPATEDNSLGMAHDLSPWGMYQNADVVVKAVMIGLAIASIMTWTIWI
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKGFELLGAKRRLRGEIANLKKARSLTEASATASTEGTLAHLLVHDALEEMRLSANSRER
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
EGIKERVSFRLERLVAACGRNMSMGTGVLATIGSTAPFVGLFGTVWGIMNSFIGIAKTQT
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
TNLAVVAPGIAEALLATALGLVAAIPAVVIYNVFARSIAGYKAQVSDASAHVLLLVSRDL
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEEECCH
DHLPEPSERNQQQPHMVKVG
HCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]