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The map label for this gene is insF1 [C]

Identifier: 66043376

GI number: 66043376

Start: 116991

End: 117812

Strand: Reverse

Name: insF1 [C]

Synonym: Psyr_0105

Alternate gene names: 66043376

Gene position: 117812-116991 (Counterclockwise)

Preceding gene: 66043377

Following gene: 66043374

Centisome position: 1.93

GC content: 56.69

Gene sequence:

>822_bases
GTGCTGGGCGTCAGTGCGACCGGCTTTCATTGCCACCAAGCTCGCTGTGCAGTTAATTGCCCTCAACGAGGTTTAAGCGA
CGCAGCATTGCTCGTCCACATTCGCGCCGCTCATGCCCGCAGTCGTGGCAGCTACGGCTGGCCCAGGATCTGGCACGGTT
TGCTGGCTGACGGCGTTCGCGTCGGCAAAGAGCGTGTGCAAAAGCTGATGCAGCTTCATGGTATTTGCGGCAAGGGCAAA
CGACGTTTCAAAGTGACCACTGATAGCGCTCATGACTTACCCATTTCGGAGAACCTGCTGGATCGCCAGTTCGCCGTGAT
GGAGCCTGACAGAGCTTGGGTGGGCGACATCACCTACATCCCGACAGATGAGGGCTGGCTGTTTCTGGCGGTAGTGGTAG
ACCTGTTCAGTCGCCAGATCGTGGGCTGGTCGATGGACGAGCGCATGAAAAGCAGCCTGGTGATTGATGCGTTGCGCATG
GCCTGGTTCAAGCGTCATCCACATAAGGCCTCCGGACTGCTGTTTCATAGTGATCGCGGGAGCCAGTACGCCAGCTTTGA
TTTTCGTCATGTCCTTCAGGGCTACGGGATTGTCAGCTCGATGAGTCGACGGGGCAATTGCTGGGATAACGCGTGCAGCG
AGACCGTGTTCGGCTCGTTGAAGGTGGAACGTCTGCATGGCTTGAAATTCAAAACCCGACGCGCTGCCAAGGACGAGGTC
ATTAACTGGCTGCTGTGGTACAACCAGGAGCGCCTGCACTCGACGCTTCATTACGTAAGTCCGATGCAATACGAGCAGAA
CTGGCAAAGGCAACAACCTTAG

Upstream 100 bases:

>100_bases
TTCTGGAAAAGGCGACGGCGTACTTCGCAAAAGCATCCAGCTGAAGTACGCGTTCATCTTTACTCATCGCCGTCTCTGGC
CTATCGGTGTGCAGTGCCGG

Downstream 100 bases:

>100_bases
ATACTCAACCCCGACGCCGGGTTAAGGGATACGTTTCTCGGGGGCAAGGTCACGTTTTATATGATGATGCTCGGTTAGGC
ATACATGTGGGCATACACTG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MLGVSATGFHCHQARCAVNCPQRGLSDAALLVHIRAAHARSRGSYGWPRIWHGLLADGVRVGKERVQKLMQLHGICGKGK
RRFKVTTDSAHDLPISENLLDRQFAVMEPDRAWVGDITYIPTDEGWLFLAVVVDLFSRQIVGWSMDERMKSSLVIDALRM
AWFKRHPHKASGLLFHSDRGSQYASFDFRHVLQGYGIVSSMSRRGNCWDNACSETVFGSLKVERLHGLKFKTRRAAKDEV
INWLLWYNQERLHSTLHYVSPMQYEQNWQRQQP

Sequences:

>Translated_273_residues
MLGVSATGFHCHQARCAVNCPQRGLSDAALLVHIRAAHARSRGSYGWPRIWHGLLADGVRVGKERVQKLMQLHGICGKGK
RRFKVTTDSAHDLPISENLLDRQFAVMEPDRAWVGDITYIPTDEGWLFLAVVVDLFSRQIVGWSMDERMKSSLVIDALRM
AWFKRHPHKASGLLFHSDRGSQYASFDFRHVLQGYGIVSSMSRRGNCWDNACSETVFGSLKVERLHGLKFKTRRAAKDEV
INWLLWYNQERLHSTLHYVSPMQYEQNWQRQQP
>Mature_273_residues
MLGVSATGFHCHQARCAVNCPQRGLSDAALLVHIRAAHARSRGSYGWPRIWHGLLADGVRVGKERVQKLMQLHGICGKGK
RRFKVTTDSAHDLPISENLLDRQFAVMEPDRAWVGDITYIPTDEGWLFLAVVVDLFSRQIVGWSMDERMKSSLVIDALRM
AWFKRHPHKASGLLFHSDRGSQYASFDFRHVLQGYGIVSSMSRRGNCWDNACSETVFGSLKVERLHGLKFKTRRAAKDEV
INWLLWYNQERLHSTLHYVSPMQYEQNWQRQQP

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=219, Percent_Identity=36.5296803652968, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1788405, Length=236, Percent_Identity=42.7966101694915, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1787263, Length=236, Percent_Identity=42.7966101694915, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1786753, Length=236, Percent_Identity=42.7966101694915, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1786570, Length=236, Percent_Identity=42.7966101694915, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1786490, Length=236, Percent_Identity=42.7966101694915, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1789981, Length=233, Percent_Identity=32.618025751073, Blast_Score=131, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31373; Mature: 31373

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGVSATGFHCHQARCAVNCPQRGLSDAALLVHIRAAHARSRGSYGWPRIWHGLLADGVR
CCCCCCCCCCHHHCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VGKERVQKLMQLHGICGKGKRRFKVTTDSAHDLPISENLLDRQFAVMEPDRAWVGDITYI
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHEECCCCCEECCEEEE
PTDEGWLFLAVVVDLFSRQIVGWSMDERMKSSLVIDALRMAWFKRHPHKASGLLFHSDRG
ECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
SQYASFDFRHVLQGYGIVSSMSRRGNCWDNACSETVFGSLKVERLHGLKFKTRRAAKDEV
CCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCEEHHHHHCCCHHHHHHHHHHH
INWLLWYNQERLHSTLHYVSPMQYEQNWQRQQP
HHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCC
>Mature Secondary Structure
MLGVSATGFHCHQARCAVNCPQRGLSDAALLVHIRAAHARSRGSYGWPRIWHGLLADGVR
CCCCCCCCCCHHHCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VGKERVQKLMQLHGICGKGKRRFKVTTDSAHDLPISENLLDRQFAVMEPDRAWVGDITYI
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHEECCCCCEECCEEEE
PTDEGWLFLAVVVDLFSRQIVGWSMDERMKSSLVIDALRMAWFKRHPHKASGLLFHSDRG
ECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
SQYASFDFRHVLQGYGIVSSMSRRGNCWDNACSETVFGSLKVERLHGLKFKTRRAAKDEV
CCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCEEHHHHHCCCHHHHHHHHHHH
INWLLWYNQERLHSTLHYVSPMQYEQNWQRQQP
HHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]