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The map label for this gene is aroE [H]

Identifier: 66043296

GI number: 66043296

Start: 28635

End: 29459

Strand: Direct

Name: aroE [H]

Synonym: Psyr_0025

Alternate gene names: 66043296

Gene position: 28635-29459 (Clockwise)

Preceding gene: 66043295

Following gene: 66043301

Centisome position: 0.47

GC content: 64.73

Gene sequence:

>825_bases
ATGGACCGGTACGTCGTCTTCGGTAATCCCATCGGCCACAGCAAGTCGCCGTTGATTCATCGCCTGTTTGCCGAGCAAAC
CGGGCAAACGCTGGATTACCAAACCTCACTGGCACCGCTGGACGATTTCACCGCGTTTGCCCAGGCGTTTTTCCAGGCCG
GGCGTGGCGCCAACGTCACCGTGCCGTTCAAGGAACAAGCCTGGCGCCTGGCCGACAGCCTGACCCAACGTGCGCAGCGC
GCCGGGGCGGTCAACACCCTGAGCAAGCTCGACGACGGAACTCTGCTGGGCGATAACACTGACGGTGCGGGGCTGGTACG
CGATCTGACGGTCAATTGCGGGCGCAGCCTGCGTGGTCAGCGCATTCTGTTGCTGGGCGCAGGCGGTGCGGTGCGTGGCG
CGCTGGAGCCGTTGCTTGGGCAACAGCCCGCTGCGTTGGTGATCGCCAATCGTACGGTCGAGAAAGCCGAGCGGCTGGCG
CAGGAGTTCGCCGACCTCGGGCCTGTATTCGCCAGCAGCTTCGACTGGCTTGAAGAGTCGGTGGACGTGATCATCAACGC
CACCTCCGCCAGCCTGGCCGGAGAGCTGCCACCGATTGCGCCCAGCCTGATCCAGCCGGGAGTGACCTTCTGCTACGACA
TGATGTACAGCAACGAGCCCACTGCTTTTTGCCGTTGGGCCACCGAGCACGGCGCGGCGCAGGCGGTGGACGGTCTGGGC
ATGCTGGTCGAGCAGGCCGCAGAAGCCTTTCTGCTGTGGCGCGGCGTGCGCCCGGATTCAGCGCCTGTATTGGCGGAGTT
GCGCAGATTGCTGGCTGCGGGTTGA

Upstream 100 bases:

>100_bases
AAGTGCGCTGGGGTTATGACTGGAAGGCCGCGCCGGGCAGCGAAGAAGCGCGTCTGACCGAATACTTCCTGACCGACCGC
GACTGGCTGGCGGAAAACTG

Downstream 100 bases:

>100_bases
TCGGCTATCTGCGGACTATCGTGCCAATGCTCCGAGTTATACATAAGTCCGCTTTTGATTCTGGCCGAAGGCCGTGGAAG
CGAACCGGGCGACGCTTCGC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MDRYVVFGNPIGHSKSPLIHRLFAEQTGQTLDYQTSLAPLDDFTAFAQAFFQAGRGANVTVPFKEQAWRLADSLTQRAQR
AGAVNTLSKLDDGTLLGDNTDGAGLVRDLTVNCGRSLRGQRILLLGAGGAVRGALEPLLGQQPAALVIANRTVEKAERLA
QEFADLGPVFASSFDWLEESVDVIINATSASLAGELPPIAPSLIQPGVTFCYDMMYSNEPTAFCRWATEHGAAQAVDGLG
MLVEQAAEAFLLWRGVRPDSAPVLAELRRLLAAG

Sequences:

>Translated_274_residues
MDRYVVFGNPIGHSKSPLIHRLFAEQTGQTLDYQTSLAPLDDFTAFAQAFFQAGRGANVTVPFKEQAWRLADSLTQRAQR
AGAVNTLSKLDDGTLLGDNTDGAGLVRDLTVNCGRSLRGQRILLLGAGGAVRGALEPLLGQQPAALVIANRTVEKAERLA
QEFADLGPVFASSFDWLEESVDVIINATSASLAGELPPIAPSLIQPGVTFCYDMMYSNEPTAFCRWATEHGAAQAVDGLG
MLVEQAAEAFLLWRGVRPDSAPVLAELRRLLAAG
>Mature_274_residues
MDRYVVFGNPIGHSKSPLIHRLFAEQTGQTLDYQTSLAPLDDFTAFAQAFFQAGRGANVTVPFKEQAWRLADSLTQRAQR
AGAVNTLSKLDDGTLLGDNTDGAGLVRDLTVNCGRSLRGQRILLLGAGGAVRGALEPLLGQQPAALVIANRTVEKAERLA
QEFADLGPVFASSFDWLEESVDVIINATSASLAGELPPIAPSLIQPGVTFCYDMMYSNEPTAFCRWATEHGAAQAVDGLG
MLVEQAAEAFLLWRGVRPDSAPVLAELRRLLAAG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=275, Percent_Identity=54.5454545454545, Blast_Score=272, Evalue=1e-74,
Organism=Escherichia coli, GI1787983, Length=268, Percent_Identity=32.089552238806, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320332, Length=270, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29327; Mature: 29327

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRYVVFGNPIGHSKSPLIHRLFAEQTGQTLDYQTSLAPLDDFTAFAQAFFQAGRGANVT
CCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
VPFKEQAWRLADSLTQRAQRAGAVNTLSKLDDGTLLGDNTDGAGLVRDLTVNCGRSLRGQ
ECHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCEECCCCCCCCHHHHHHHHCCCCCCCC
RILLLGAGGAVRGALEPLLGQQPAALVIANRTVEKAERLAQEFADLGPVFASSFDWLEES
EEEEEECCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VDVIINATSASLAGELPPIAPSLIQPGVTFCYDMMYSNEPTAFCRWATEHGAAQAVDGLG
HHHEEECCHHHHCCCCCCCCHHHHCCHHHHHHHHHHCCCCCCEEEECHHCCHHHHHHHHH
MLVEQAAEAFLLWRGVRPDSAPVLAELRRLLAAG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDRYVVFGNPIGHSKSPLIHRLFAEQTGQTLDYQTSLAPLDDFTAFAQAFFQAGRGANVT
CCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
VPFKEQAWRLADSLTQRAQRAGAVNTLSKLDDGTLLGDNTDGAGLVRDLTVNCGRSLRGQ
ECHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCEECCCCCCCCHHHHHHHHCCCCCCCC
RILLLGAGGAVRGALEPLLGQQPAALVIANRTVEKAERLAQEFADLGPVFASSFDWLEES
EEEEEECCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VDVIINATSASLAGELPPIAPSLIQPGVTFCYDMMYSNEPTAFCRWATEHGAAQAVDGLG
HHHEEECCHHHHCCCCCCCCHHHHCCHHHHHHHHHHCCCCCCEEEECHHCCHHHHHHHHH
MLVEQAAEAFLLWRGVRPDSAPVLAELRRLLAAG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA