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The map label for this gene is hpaG [C]

Identifier: 62391870

GI number: 62391870

Start: 3198023

End: 3198862

Strand: Reverse

Name: hpaG [C]

Synonym: cg3350

Alternate gene names: 62391870

Gene position: 3198862-3198023 (Counterclockwise)

Preceding gene: 62391871

Following gene: 62391869

Centisome position: 97.45

GC content: 54.4

Gene sequence:

>840_bases
ATGCGTCTTGCAACAATCCGCACCAACGGCACCACCATTGCTGCTCGTGTTGAATCTGAAAACACCGCTACCACCATCGA
GGGCTTTGCCAACGTCGGTGAATTACTCCAGGAATCCAACTGGCGCGAGCTGGCAGAAAACGCTGCTGGTGAGGCTGTGA
CCTTTGAAAACAAGGAGCTAGATGCAGTAGTTCCAGCACCTAAGAAGATTGTGTGCGTCGGCCTTAACTACGCCAACCAC
ATTAAAGAAATGGGCCGCGACCTCCCTGATACCCCAACCCTTTTTGTTAAGTTCCCTGACGCGCTCATCGGACCTTTCGA
TGATGTTGTCGTTCCAGAGTGGGCTAACAAGGCTCTCGACTGGGAAGGCGAGATGGCAGTTATCATTGGCAAGCGCGCAC
GCCGTGTCAAGCAGGCCGATGCTGCTGAGTACATCGCTGGCTACGCAGTGATGAACGATTACACCACCCGCGATTTCCAG
TACGCAGCACCTGCAAAGACTCCACAGTGGCACCAGGGCAAGTCTTTGGAAAAGTCCGCTGGCTTCGGGCCTTGGATGAC
TACCCCAGATTCTTTTGAGTTCGGCGGCGAGCTGGCAACCTACCTCGAGGGCGAGAAGGTACAGTCCACCCCTACCAATG
ACCTGGTCTTTAGCCCAGAAAAGCTCATCGAATACATCACCCACATCTACCCATTGGATGCTGGCGACGTCATTGTCACC
GGTACCCCAGGCGGCGTTGGCCACGCACGTAACCCACAGCGCTACATCGGTGACGGCGAAACCGTAAAGGTTGAGATTGC
GGGCCTCGGCTTCATTGAAAACAAGACGGTGTTTGAATAA

Upstream 100 bases:

>100_bases
CTGGCTCTGACGGCGTCGACTTGTTCTGCTTCTCTGATACACCAATTTTCGAGGCCCTTAACCTCGCACGTACTTTTACT
CCGGAAGGAATCTAGAACTT

Downstream 100 bases:

>100_bases
ATGACAACTTTCCACGATCTTCCGCTGGAGGAGCGGCTGACACTGGCCAGGTTGGGCACATCCCACTACTCCCGTCAGCT
CTCCCTCGTGGACAACGCTG

Product: bifunctional enzyme 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRLATIRTNGTTIAARVESENTATTIEGFANVGELLQESNWRELAENAAGEAVTFENKELDAVVPAPKKIVCVGLNYANH
IKEMGRDLPDTPTLFVKFPDALIGPFDDVVVPEWANKALDWEGEMAVIIGKRARRVKQADAAEYIAGYAVMNDYTTRDFQ
YAAPAKTPQWHQGKSLEKSAGFGPWMTTPDSFEFGGELATYLEGEKVQSTPTNDLVFSPEKLIEYITHIYPLDAGDVIVT
GTPGGVGHARNPQRYIGDGETVKVEIAGLGFIENKTVFE

Sequences:

>Translated_279_residues
MRLATIRTNGTTIAARVESENTATTIEGFANVGELLQESNWRELAENAAGEAVTFENKELDAVVPAPKKIVCVGLNYANH
IKEMGRDLPDTPTLFVKFPDALIGPFDDVVVPEWANKALDWEGEMAVIIGKRARRVKQADAAEYIAGYAVMNDYTTRDFQ
YAAPAKTPQWHQGKSLEKSAGFGPWMTTPDSFEFGGELATYLEGEKVQSTPTNDLVFSPEKLIEYITHIYPLDAGDVIVT
GTPGGVGHARNPQRYIGDGETVKVEIAGLGFIENKTVFE
>Mature_279_residues
MRLATIRTNGTTIAARVESENTATTIEGFANVGELLQESNWRELAENAAGEAVTFENKELDAVVPAPKKIVCVGLNYANH
IKEMGRDLPDTPTLFVKFPDALIGPFDDVVVPEWANKALDWEGEMAVIIGKRARRVKQADAAEYIAGYAVMNDYTTRDFQ
YAAPAKTPQWHQGKSLEKSAGFGPWMTTPDSFEFGGELATYLEGEKVQSTPTNDLVFSPEKLIEYITHIYPLDAGDVIVT
GTPGGVGHARNPQRYIGDGETVKVEIAGLGFIENKTVFE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=218, Percent_Identity=40.3669724770642, Blast_Score=168, Evalue=5e-42,
Organism=Homo sapiens, GI40786394, Length=213, Percent_Identity=39.906103286385, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI66348062, Length=183, Percent_Identity=37.1584699453552, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI215422413, Length=183, Percent_Identity=37.1584699453552, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI13654274, Length=183, Percent_Identity=37.1584699453552, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1787428, Length=187, Percent_Identity=36.8983957219251, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17557057, Length=181, Percent_Identity=38.6740331491713, Blast_Score=124, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6324161, Length=220, Percent_Identity=26.3636363636364, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28572127, Length=247, Percent_Identity=36.0323886639676, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24663695, Length=218, Percent_Identity=29.3577981651376, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28571789, Length=181, Percent_Identity=32.0441988950276, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 30559; Mature: 30559

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLATIRTNGTTIAARVESENTATTIEGFANVGELLQESNWRELAENAAGEAVTFENKEL
CEEEEEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCC
DAVVPAPKKIVCVGLNYANHIKEMGRDLPDTPTLFVKFPDALIGPFDDVVVPEWANKALD
EEECCCCCEEEEEECCHHHHHHHHHCCCCCCCEEEEECCHHHHCCCCCCCCCHHHCCCCC
WEGEMAVIIGKRARRVKQADAAEYIAGYAVMNDYTTRDFQYAAPAKTPQWHQGKSLEKSA
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHC
GFGPWMTTPDSFEFGGELATYLEGEKVQSTPTNDLVFSPEKLIEYITHIYPLDAGDVIVT
CCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHCCCCCCCEEEE
GTPGGVGHARNPQRYIGDGETVKVEIAGLGFIENKTVFE
CCCCCCCCCCCCHHHCCCCCEEEEEEEEEEEECCCCCCC
>Mature Secondary Structure
MRLATIRTNGTTIAARVESENTATTIEGFANVGELLQESNWRELAENAAGEAVTFENKEL
CEEEEEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCC
DAVVPAPKKIVCVGLNYANHIKEMGRDLPDTPTLFVKFPDALIGPFDDVVVPEWANKALD
EEECCCCCEEEEEECCHHHHHHHHHCCCCCCCEEEEECCHHHHCCCCCCCCCHHHCCCCC
WEGEMAVIIGKRARRVKQADAAEYIAGYAVMNDYTTRDFQYAAPAKTPQWHQGKSLEKSA
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHC
GFGPWMTTPDSFEFGGELATYLEGEKVQSTPTNDLVFSPEKLIEYITHIYPLDAGDVIVT
CCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHCCCCCCCEEEE
GTPGGVGHARNPQRYIGDGETVKVEIAGLGFIENKTVFE
CCCCCCCCCCCCHHHCCCCCEEEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]