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The map label for this gene is msrA [H]

Identifier: 62391763

GI number: 62391763

Start: 3098799

End: 3099452

Strand: Reverse

Name: msrA [H]

Synonym: cg3236

Alternate gene names: 62391763

Gene position: 3099452-3098799 (Counterclockwise)

Preceding gene: 62391765

Following gene: 62391761

Centisome position: 94.42

GC content: 55.35

Gene sequence:

>654_bases
ATGGCATGGTTTTTCGCACCCGAACCCGTGATGGTTACCGCTGATGAGGCGCTTAAAGGTGGCAGGCATCCTGTTTTAGA
AAATCCTGCGCCGCACACTGTGTTGGGAACTCCTGTGACTGGTCCGTGGAAAGAAGGCCAGCAGCGAATTTGGATTGGCC
TTGGTTGTTTCTGGGGTGTGGAGCAAATGTATTGGCAGATGGATGGCGTTGAGGGAACTTCGGTTGGTTACGCCGGCGGT
TTCACCCCTAATCCCACTTATCGCGAGGTGTGTTCTGGGCGCACCGGCCACACTGAAATCGTGGAGGTTGTTTACGATCC
TTCGAAGATTTCCCTCGAGCAGCTTGTTGCCCGCGGCCTGGAAGCACACGATCCGACTCAGGGTTTCCGCCAGGGTAACG
ATGTGGGAACGCAGTACCGCTCTGCTTATTACACCGAGAACGAAGAGGACGCTGCGCGCGTAAAAGCCGTGGTCGATGCC
TATGGTGAGACGCTGAAGCAGCACGGTTTTGGTGAAATCACCACGGAAATCGGTGTCATTAGCCCGTCTGACTACTTCCT
CGCCGAGGATTACCACCAGCAATACCTGGACAAGAATCCCGATGGCTACTGCCCTCATCACTCCACGGGCATCCCGTGCG
GGGTAGAAGCTTAA

Upstream 100 bases:

>100_bases
CTATTTATCGGGTAGCGGGTCACAAGCCCGGAATAATTGGCAGCTAAGTAGGGTTGAAGGGCATAAGGCTTCCTCAATTT
TCGAAAGGAACATTCCTGTT

Downstream 100 bases:

>100_bases
AAGATTTTTGCTTTTCGACGCATCCCTCCACCTCGGATTACGCCTGAGGCATGACTATCGTCGCGCTTCTTTCCGACCTG
GACAACACGCGTAGCTACCG

Product: methionine sulfoxide reductase A

Products: NA

Alternate protein names: Protein-methionine-S-oxide reductase; Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MAWFFAPEPVMVTADEALKGGRHPVLENPAPHTVLGTPVTGPWKEGQQRIWIGLGCFWGVEQMYWQMDGVEGTSVGYAGG
FTPNPTYREVCSGRTGHTEIVEVVYDPSKISLEQLVARGLEAHDPTQGFRQGNDVGTQYRSAYYTENEEDAARVKAVVDA
YGETLKQHGFGEITTEIGVISPSDYFLAEDYHQQYLDKNPDGYCPHHSTGIPCGVEA

Sequences:

>Translated_217_residues
MAWFFAPEPVMVTADEALKGGRHPVLENPAPHTVLGTPVTGPWKEGQQRIWIGLGCFWGVEQMYWQMDGVEGTSVGYAGG
FTPNPTYREVCSGRTGHTEIVEVVYDPSKISLEQLVARGLEAHDPTQGFRQGNDVGTQYRSAYYTENEEDAARVKAVVDA
YGETLKQHGFGEITTEIGVISPSDYFLAEDYHQQYLDKNPDGYCPHHSTGIPCGVEA
>Mature_216_residues
AWFFAPEPVMVTADEALKGGRHPVLENPAPHTVLGTPVTGPWKEGQQRIWIGLGCFWGVEQMYWQMDGVEGTSVGYAGGF
TPNPTYREVCSGRTGHTEIVEVVYDPSKISLEQLVARGLEAHDPTQGFRQGNDVGTQYRSAYYTENEEDAARVKAVVDAY
GETLKQHGFGEITTEIGVISPSDYFLAEDYHQQYLDKNPDGYCPHHSTGIPCGVEA

Specific function: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine [H]

COG id: COG0225

COG function: function code O; Peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrA Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI6912516, Length=205, Percent_Identity=48.780487804878, Blast_Score=193, Evalue=1e-49,
Organism=Homo sapiens, GI208609995, Length=184, Percent_Identity=50.5434782608696, Blast_Score=188, Evalue=3e-48,
Organism=Homo sapiens, GI208609993, Length=122, Percent_Identity=50, Blast_Score=120, Evalue=6e-28,
Organism=Escherichia coli, GI1790665, Length=191, Percent_Identity=48.6910994764398, Blast_Score=168, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17533973, Length=151, Percent_Identity=37.7483443708609, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6320881, Length=169, Percent_Identity=37.8698224852071, Blast_Score=102, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24664627, Length=146, Percent_Identity=34.9315068493151, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45553131, Length=144, Percent_Identity=34.7222222222222, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24664631, Length=146, Percent_Identity=33.5616438356164, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002569 [H]

Pfam domain/function: PF01625 PMSR [H]

EC number: =1.8.4.11 [H]

Molecular weight: Translated: 23931; Mature: 23800

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWFFAPEPVMVTADEALKGGRHPVLENPAPHTVLGTPVTGPWKEGQQRIWIGLGCFWGV
CCCEECCCCEEEECHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEECHHHHHH
EQMYWQMDGVEGTSVGYAGGFTPNPTYREVCSGRTGHTEIVEVVYDPSKISLEQLVARGL
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHCCC
EAHDPTQGFRQGNDVGTQYRSAYYTENEEDAARVKAVVDAYGETLKQHGFGEITTEIGVI
CCCCCHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHEEEEE
SPSDYFLAEDYHQQYLDKNPDGYCPHHSTGIPCGVEA
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AWFFAPEPVMVTADEALKGGRHPVLENPAPHTVLGTPVTGPWKEGQQRIWIGLGCFWGV
CCEECCCCEEEECHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEECHHHHHH
EQMYWQMDGVEGTSVGYAGGFTPNPTYREVCSGRTGHTEIVEVVYDPSKISLEQLVARGL
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHCCC
EAHDPTQGFRQGNDVGTQYRSAYYTENEEDAARVKAVVDAYGETLKQHGFGEITTEIGVI
CCCCCHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHEEEEE
SPSDYFLAEDYHQQYLDKNPDGYCPHHSTGIPCGVEA
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA