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The map label for this gene is pheA

Identifier: 62391736

GI number: 62391736

Start: 3071882

End: 3072829

Strand: Reverse

Name: pheA

Synonym: cg3207

Alternate gene names: 62391736

Gene position: 3072829-3071882 (Counterclockwise)

Preceding gene: 62391743

Following gene: 62391735

Centisome position: 93.61

GC content: 61.6

Gene sequence:

>948_bases
ATGAGCGACGCACCAACTGTTGTGGCCTATTTGGGGCCTGCCGGAACCTTCACCGAAGAAGCCCTCTACAAATTTGCCGA
CGCCGGCGTATTCGGCGACGGTGAGATCGAGCAGCTACCAGCCAAATCGCCACAAGAAGCTGTCGACGCCGTCCGCCACG
GCACCGCCCAGTTCGCGGTGGTCGCCATCGAAAACTTCGTCGACGGCCCCGTCACCCCCACCTTCGACGCCCTTGACCAG
GGCTCCAACGTGCAAATCATCGCCGAAGAAGAACTCGACATCGCCTTTTCCATCATGGTCCGGCCAGGGACTTCGCTTGC
CGACGTCAAAACCCTCGCCACCCACCCGGTTGGGTACCAACAAGTGAAAAACTGGATGGCAACCACCATTCCGGACGCCA
TGTATCTTTCAGCAAGCTCCAACGGCGCCGGCGCACAAATGGTTGCCGAAGGAACCGCCGACGCAGCCGCAGCGCCCTCC
CGCGCAGCCGAACTCTTCGGACTGGAACGCCTTGTTGATGATGTCGCCGACGTCCGTGGCGCCCGCACCCGCTTCGTTGC
TGTCCAAGCCCAAGCAGCCGTTTCCGAACCGACCGGCCACGACCGCACCTCCGTCATTTTCTCCCTACCGAATGTGCCAG
GCAGCCTCGTGCGCGCCCTCAACGAATTCGCCATCCGCGGCGTTGACCTCACCCGCATCGAATCCCGCCCCACCCGCAAA
GTCTTCGGAACCTACCGCTTCCACCTGGACATATCCGGACATATCCGCGATATCCCCGTCGCCGAAGCCCTCCGCGCACT
CCACCTCCAAGCCGAAGAACTCGTCTTCGTCGGCTCCTGGCCCTCCAACCGTGCGGAAGACAGCACGCCCCAAACCGACC
AACTAGCTAAGCTACACAAGGCGGACGAATGGGTTCGCGCAGCAAGCGAAGGAAGGAAACTTAACTAG

Upstream 100 bases:

>100_bases
CAAAACCATGCTCGGCGGGGGAGAGTTGGGCCAAGCGGTTCGCTAATTGAGCAACAGACATGGACACCCACCTTAGTTCG
GCGGGTTAAGCTGTGTAACC

Downstream 100 bases:

>100_bases
CCATGGCCGGCCGGATTATTTTGCTACGACACGGGCAGACTCACAACAACGTCAAACACCTCCTGGACACCCGCCCACCA
GGAGCTGAACTCACCGACCT

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSDAPTVVAYLGPAGTFTEEALYKFADAGVFGDGEIEQLPAKSPQEAVDAVRHGTAQFAVVAIENFVDGPVTPTFDALDQ
GSNVQIIAEEELDIAFSIMVRPGTSLADVKTLATHPVGYQQVKNWMATTIPDAMYLSASSNGAGAQMVAEGTADAAAAPS
RAAELFGLERLVDDVADVRGARTRFVAVQAQAAVSEPTGHDRTSVIFSLPNVPGSLVRALNEFAIRGVDLTRIESRPTRK
VFGTYRFHLDISGHIRDIPVAEALRALHLQAEELVFVGSWPSNRAEDSTPQTDQLAKLHKADEWVRAASEGRKLN

Sequences:

>Translated_315_residues
MSDAPTVVAYLGPAGTFTEEALYKFADAGVFGDGEIEQLPAKSPQEAVDAVRHGTAQFAVVAIENFVDGPVTPTFDALDQ
GSNVQIIAEEELDIAFSIMVRPGTSLADVKTLATHPVGYQQVKNWMATTIPDAMYLSASSNGAGAQMVAEGTADAAAAPS
RAAELFGLERLVDDVADVRGARTRFVAVQAQAAVSEPTGHDRTSVIFSLPNVPGSLVRALNEFAIRGVDLTRIESRPTRK
VFGTYRFHLDISGHIRDIPVAEALRALHLQAEELVFVGSWPSNRAEDSTPQTDQLAKLHKADEWVRAASEGRKLN
>Mature_314_residues
SDAPTVVAYLGPAGTFTEEALYKFADAGVFGDGEIEQLPAKSPQEAVDAVRHGTAQFAVVAIENFVDGPVTPTFDALDQG
SNVQIIAEEELDIAFSIMVRPGTSLADVKTLATHPVGYQQVKNWMATTIPDAMYLSASSNGAGAQMVAEGTADAAAAPSR
AAELFGLERLVDDVADVRGARTRFVAVQAQAAVSEPTGHDRTSVIFSLPNVPGSLVRALNEFAIRGVDLTRIESRPTRKV
FGTYRFHLDISGHIRDIPVAEALRALHLQAEELVFVGSWPSNRAEDSTPQTDQLAKLHKADEWVRAASEGRKLN

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain

Homologues:

Organism=Escherichia coli, GI1788951, Length=277, Percent_Identity=28.5198555956679, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHEA_CORGL (P10341)

Other databases:

- EMBL:   M13774
- EMBL:   BA000036
- EMBL:   BX927156
- PIR:   A26044
- RefSeq:   NP_602088.1
- RefSeq:   YP_227138.1
- ProteinModelPortal:   P10341
- SMR:   P10341
- GeneID:   1020842
- GeneID:   3343256
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg3207
- KEGG:   cgl:NCgl2799
- HOGENOM:   HBG693866
- OMA:   CRKWLDA
- ProtClustDB:   PRK11898
- BioCyc:   CGLU196627:CG3207-MONOMER
- BRENDA:   4.2.1.51
- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528

Pfam domain/function: PF01842 ACT; PF00800 PDT

EC number: =4.2.1.51

Molecular weight: Translated: 33740; Mature: 33609

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00857 PREPHENATE_DEHYDR_1; PS00858 PREPHENATE_DEHYDR_2; PS51171 PREPHENATE_DEHYDR_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAPTVVAYLGPAGTFTEEALYKFADAGVFGDGEIEQLPAKSPQEAVDAVRHGTAQFAV
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHCCCHHEEE
VAIENFVDGPVTPTFDALDQGSNVQIIAEEELDIAFSIMVRPGTSLADVKTLATHPVGYQ
EEEHHHCCCCCCCCHHHHCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHCCCCCHH
QVKNWMATTIPDAMYLSASSNGAGAQMVAEGTADAAAAPSRAAELFGLERLVDDVADVRG
HHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHCC
ARTRFVAVQAQAAVSEPTGHDRTSVIFSLPNVPGSLVRALNEFAIRGVDLTRIESRPTRK
CCEEEEEEEEHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEECCCCCCCE
VFGTYRFHLDISGHIRDIPVAEALRALHLQAEELVFVGSWPSNRAEDSTPQTDQLAKLHK
EEEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCCHHHHHHHHH
ADEWVRAASEGRKLN
HHHHHHHHHCCCCCC
>Mature Secondary Structure 
SDAPTVVAYLGPAGTFTEEALYKFADAGVFGDGEIEQLPAKSPQEAVDAVRHGTAQFAV
CCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHCCCHHEEE
VAIENFVDGPVTPTFDALDQGSNVQIIAEEELDIAFSIMVRPGTSLADVKTLATHPVGYQ
EEEHHHCCCCCCCCHHHHCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHCCCCCHH
QVKNWMATTIPDAMYLSASSNGAGAQMVAEGTADAAAAPSRAAELFGLERLVDDVADVRG
HHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHCC
ARTRFVAVQAQAAVSEPTGHDRTSVIFSLPNVPGSLVRALNEFAIRGVDLTRIESRPTRK
CCEEEEEEEEHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEECCCCCCCE
VFGTYRFHLDISGHIRDIPVAEALRALHLQAEELVFVGSWPSNRAEDSTPQTDQLAKLHK
EEEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCCHHHHHHHHH
ADEWVRAASEGRKLN
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3525519; 12948626