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The map label for this gene is panC [H]

Identifier: 62391525

GI number: 62391525

Start: 2835437

End: 2836237

Strand: Reverse

Name: panC [H]

Synonym: cg2975

Alternate gene names: 62391525

Gene position: 2836237-2835437 (Counterclockwise)

Preceding gene: 62391526

Following gene: 62391524

Centisome position: 86.4

GC content: 57.18

Gene sequence:

>801_bases
TTGAGTTTCACGCATGGTCAGGGCAGAGTTTTTGATACCGTCGAGCAGATCCGCATGTTCGGCAGCGCCCTGCGCAAAAC
CGGCAAACCAGTGGTGCTCGTACCCTTGGGAAATGGCCTCCACGCAGGCCATATTGCGCTCATCCGCGCAGCAAAACGCA
TCCCCGGTGCGGTGGTCGTCGTCGCCTATGCCGGCCCGGAATCGGATCACGCACGTTTAAGGGAAGAGCTTATCGACGCG
ATCTTCCCGTTCAATCCCGAAACGCTATGGCCTCACGGCATCCGGGTGGAAGTTACAGGTGGCCCAACACTTACCCCACA
AGGTGCGGAAGTAACCAAGGTGCTGGGGCTGTTGGGAATCACCGGAGCAACTGATGTGGTGCTCGGTGAAAAGGACTATG
AGCTGGTGGTTCTAGTCCAGCGCGCCCTTAATGATCTGCATATTCCAGTAAAACTGCATTCTGTTCCAACCGTGCGCATG
CCAGATGGACTAGCCATTTCCCTGCGTAATATTTCAGTGCCCGAAGACTCCCGCGAAACGGCATTGAGCCTGGCAGCAGC
CCTCACCGCCGGTGCGCATTCGGCAGAACACGGCGAGGCAGTGGTTAAAGAAACAGTCACGCAAGTGCTCAAAGCCGCAG
GCGTGACCCCCGATTATGTAGAAATCCGTGGCCTGGATCTTGGACCAGCCCCCGAAATCGGAGACGCCCGACTCTTCGCA
GCCATCACGCTTGGCGATGTCCAACTCCACGACAACGTCGGCCTACCCCTTGGAATCGGCTTCAAAAACATCGAAGGCTG
A

Upstream 100 bases:

>100_bases
ACCCCGGCAGGCAACGCCTTTTCCGGGATTTGGCGCGCAGGCAGGCAGAGATTTCCCGCGCGCAAGATATTGAGCTGTGG
GCAATTCAGAAGGAGGACCG

Downstream 100 bases:

>100_bases
TCCCGGTTTACCCAGTTCGCATACCTTTCGACTACCCTAGGAAATCGTGACTAATTCCAATCCCACTTCCAAGAACAATT
CCGCCGATTTGCCTGAGCAG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MSFTHGQGRVFDTVEQIRMFGSALRKTGKPVVLVPLGNGLHAGHIALIRAAKRIPGAVVVVAYAGPESDHARLREELIDA
IFPFNPETLWPHGIRVEVTGGPTLTPQGAEVTKVLGLLGITGATDVVLGEKDYELVVLVQRALNDLHIPVKLHSVPTVRM
PDGLAISLRNISVPEDSRETALSLAAALTAGAHSAEHGEAVVKETVTQVLKAAGVTPDYVEIRGLDLGPAPEIGDARLFA
AITLGDVQLHDNVGLPLGIGFKNIEG

Sequences:

>Translated_266_residues
MSFTHGQGRVFDTVEQIRMFGSALRKTGKPVVLVPLGNGLHAGHIALIRAAKRIPGAVVVVAYAGPESDHARLREELIDA
IFPFNPETLWPHGIRVEVTGGPTLTPQGAEVTKVLGLLGITGATDVVLGEKDYELVVLVQRALNDLHIPVKLHSVPTVRM
PDGLAISLRNISVPEDSRETALSLAAALTAGAHSAEHGEAVVKETVTQVLKAAGVTPDYVEIRGLDLGPAPEIGDARLFA
AITLGDVQLHDNVGLPLGIGFKNIEG
>Mature_265_residues
SFTHGQGRVFDTVEQIRMFGSALRKTGKPVVLVPLGNGLHAGHIALIRAAKRIPGAVVVVAYAGPESDHARLREELIDAI
FPFNPETLWPHGIRVEVTGGPTLTPQGAEVTKVLGLLGITGATDVVLGEKDYELVVLVQRALNDLHIPVKLHSVPTVRMP
DGLAISLRNISVPEDSRETALSLAAALTAGAHSAEHGEAVVKETVTQVLKAAGVTPDYVEIRGLDLGPAPEIGDARLFAA
ITLGDVQLHDNVGLPLGIGFKNIEG

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=276, Percent_Identity=27.8985507246377, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 28065; Mature: 27934

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTHGQGRVFDTVEQIRMFGSALRKTGKPVVLVPLGNGLHAGHIALIRAAKRIPGAVVV
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEE
VAYAGPESDHARLREELIDAIFPFNPETLWPHGIRVEVTGGPTLTPQGAEVTKVLGLLGI
EEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCC
TGATDVVLGEKDYELVVLVQRALNDLHIPVKLHSVPTVRMPDGLAISLRNISVPEDSRET
CCCCEEEECCCCCEEEEEEHHHHHHCCCEEEEECCCEEECCCCCEEEEEECCCCCCHHHH
ALSLAAALTAGAHSAEHGEAVVKETVTQVLKAAGVTPDYVEIRGLDLGPAPEIGDARLFA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEE
AITLGDVQLHDNVGLPLGIGFKNIEG
EEEECCEEEECCCCCEEECCCCCCCC
>Mature Secondary Structure 
SFTHGQGRVFDTVEQIRMFGSALRKTGKPVVLVPLGNGLHAGHIALIRAAKRIPGAVVV
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEE
VAYAGPESDHARLREELIDAIFPFNPETLWPHGIRVEVTGGPTLTPQGAEVTKVLGLLGI
EEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCC
TGATDVVLGEKDYELVVLVQRALNDLHIPVKLHSVPTVRMPDGLAISLRNISVPEDSRET
CCCCEEEECCCCCEEEEEEHHHHHHCCCEEEEECCCEEECCCCCEEEEEECCCCCCHHHH
ALSLAAALTAGAHSAEHGEAVVKETVTQVLKAAGVTPDYVEIRGLDLGPAPEIGDARLFA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEE
AITLGDVQLHDNVGLPLGIGFKNIEG
EEEECCEEEECCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA