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The map label for this gene is cysS [H]

Identifier: 62391480

GI number: 62391480

Start: 2781705

End: 2783087

Strand: Reverse

Name: cysS [H]

Synonym: cg2924

Alternate gene names: 62391480

Gene position: 2783087-2781705 (Counterclockwise)

Preceding gene: 62391481

Following gene: 62391479

Centisome position: 84.78

GC content: 52.42

Gene sequence:

>1383_bases
GTGACTCTACGCATCTTTGACACCGGTACCCGTACGCTTCGAGATTTTAAACCTGTTCAACCAGGTCATGCCTCGGTGTA
CCTGTGTGGTGCCACCCCGCAATCTTCACCCCACATTGGACATGTTCGTTCAGCAGTAGCGTTTGATATTTTGCGCCGCT
GGCTCATGGCTAAGGGACTTGATGTGGCATTTGTTCGCAATGTCACTGATATCGATGACAAGATTCTCACCAAGGCATCT
GAAAATGGTCGCCCTTGGTGGGAATGGGTGTCCACCTATGAACGTGAATTCACCTGGACGTACAACACGTTGGGTGTGCT
TCCTCCATCAACGGAGCCTCGTGCAACAGGCCACGTCACTCAGATGATTAAGTACATGCAGCGCTTGATTGATAACGGCT
TTGCTTACGCCGTTGATGGCTCTGTGTACTTTGATGTCGCAGCGTGGTCCAAGGCTGAAGGATCTGACTATGGTTCTTTG
TCCGGAAACCGTGTTGAAGATATGGAGCAGGGCGAGCCCGATAACTTTGGTAAGCGGGGGCCACAGGACTTTGCTCTGTG
GAAGGCTGCCAAACCGGGTGAGCCGTCATGGCCAACCCCTTGGGGAGACGGCCGGCCGGGTTGGCATTTGGAATGCTCTG
CCATGGCCACCTACTATTTGGGTGAGCAATTTGATATTCACTGTGGTGGTTTGGATCTGCAATTTCCACACCATGAAAAT
GAAATTGCCCAGGCACATGCGGCTGGCGATAAATTTGCCAACTACTGGATGCACAATCACTGGGTAACAATGGCCGGCGA
GAAAATGTCCAAGTCTTTGGGCAATGTTTTGGCTGTGCCGGAAATGCTAAAGCAGGTTCGTCCTGTCGAGCTTCGTTATT
ACCTTGGGTCTGCCCATTACCGTTCCGTCCTTGAGTATTCCGAGAGCGCTTTGAGTGAAGCTGCGGTGGGTTACCGTCGC
ATTGAGTCTTTCCTTGAGCGTGTGGGGGATGTTGAGGTAGGCGAGTGGACGCCAGGTTTTGAAGTTGCGATGGATGAGGA
TATTGCAGTTCCTAAGGCTTTGGCTGAAATCCATAACGCTGTCCGCGAGGGCAATGCTGCCTTGGATAAGGGTGATCGTG
AGGCAGCGGAGAAGCTTGCTTCCTCGGTTCGTGCGATGACTGGCGTTTTGGGCTTCGACCCCGTTGAATGGGGTTCAGAT
GCAGGCGCTGATGGCAAGGCAGATAAGGCGCTTGATGTGCTGATTTCTTCGGAGCTTGAGCGTCGTGCAACTGCTCGTGC
TGAGAAGAATTGGGCGGTTGCTGATGAGGTTCGAGATCGTCTTGCCGATGCTGGTATTGAGGTTGTGGATACCGCAGATG
GCGCTACATGGAAATTGCAGTAA

Upstream 100 bases:

>100_bases
AGCGGGAGCCAACCTGCTCAACGTCGCAAAGAAAGAAGCGGTGCCAGCAACACCATAAGTTGAAACCTTGAGTGTTCGCA
CACAGGTTAGACTAGGGGAC

Downstream 100 bases:

>100_bases
TTACAGACACTTTTAAGGAGATAATTTAAACATGGCAGGAAATGACAGTCGTCGAGGCGGCTTACGCAAGACCAATAAAA
AAGGTGCAACCAAGGGCAGT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MTLRIFDTGTRTLRDFKPVQPGHASVYLCGATPQSSPHIGHVRSAVAFDILRRWLMAKGLDVAFVRNVTDIDDKILTKAS
ENGRPWWEWVSTYEREFTWTYNTLGVLPPSTEPRATGHVTQMIKYMQRLIDNGFAYAVDGSVYFDVAAWSKAEGSDYGSL
SGNRVEDMEQGEPDNFGKRGPQDFALWKAAKPGEPSWPTPWGDGRPGWHLECSAMATYYLGEQFDIHCGGLDLQFPHHEN
EIAQAHAAGDKFANYWMHNHWVTMAGEKMSKSLGNVLAVPEMLKQVRPVELRYYLGSAHYRSVLEYSESALSEAAVGYRR
IESFLERVGDVEVGEWTPGFEVAMDEDIAVPKALAEIHNAVREGNAALDKGDREAAEKLASSVRAMTGVLGFDPVEWGSD
AGADGKADKALDVLISSELERRATARAEKNWAVADEVRDRLADAGIEVVDTADGATWKLQ

Sequences:

>Translated_460_residues
MTLRIFDTGTRTLRDFKPVQPGHASVYLCGATPQSSPHIGHVRSAVAFDILRRWLMAKGLDVAFVRNVTDIDDKILTKAS
ENGRPWWEWVSTYEREFTWTYNTLGVLPPSTEPRATGHVTQMIKYMQRLIDNGFAYAVDGSVYFDVAAWSKAEGSDYGSL
SGNRVEDMEQGEPDNFGKRGPQDFALWKAAKPGEPSWPTPWGDGRPGWHLECSAMATYYLGEQFDIHCGGLDLQFPHHEN
EIAQAHAAGDKFANYWMHNHWVTMAGEKMSKSLGNVLAVPEMLKQVRPVELRYYLGSAHYRSVLEYSESALSEAAVGYRR
IESFLERVGDVEVGEWTPGFEVAMDEDIAVPKALAEIHNAVREGNAALDKGDREAAEKLASSVRAMTGVLGFDPVEWGSD
AGADGKADKALDVLISSELERRATARAEKNWAVADEVRDRLADAGIEVVDTADGATWKLQ
>Mature_459_residues
TLRIFDTGTRTLRDFKPVQPGHASVYLCGATPQSSPHIGHVRSAVAFDILRRWLMAKGLDVAFVRNVTDIDDKILTKASE
NGRPWWEWVSTYEREFTWTYNTLGVLPPSTEPRATGHVTQMIKYMQRLIDNGFAYAVDGSVYFDVAAWSKAEGSDYGSLS
GNRVEDMEQGEPDNFGKRGPQDFALWKAAKPGEPSWPTPWGDGRPGWHLECSAMATYYLGEQFDIHCGGLDLQFPHHENE
IAQAHAAGDKFANYWMHNHWVTMAGEKMSKSLGNVLAVPEMLKQVRPVELRYYLGSAHYRSVLEYSESALSEAAVGYRRI
ESFLERVGDVEVGEWTPGFEVAMDEDIAVPKALAEIHNAVREGNAALDKGDREAAEKLASSVRAMTGVLGFDPVEWGSDA
GADGKADKALDVLISSELERRATARAEKNWAVADEVRDRLADAGIEVVDTADGATWKLQ

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=374, Percent_Identity=38.5026737967914, Blast_Score=241, Evalue=7e-64,
Organism=Homo sapiens, GI21269877, Length=299, Percent_Identity=39.7993311036789, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI10835051, Length=299, Percent_Identity=39.7993311036789, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI303304987, Length=299, Percent_Identity=39.7993311036789, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI62240992, Length=299, Percent_Identity=39.7993311036789, Blast_Score=211, Evalue=1e-54,
Organism=Escherichia coli, GI1786737, Length=464, Percent_Identity=42.2413793103448, Blast_Score=333, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI17509797, Length=312, Percent_Identity=37.1794871794872, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17509795, Length=312, Percent_Identity=37.1794871794872, Blast_Score=195, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6324082, Length=390, Percent_Identity=33.0769230769231, Blast_Score=211, Evalue=1e-55,
Organism=Drosophila melanogaster, GI19922218, Length=502, Percent_Identity=31.8725099601594, Blast_Score=235, Evalue=6e-62,
Organism=Drosophila melanogaster, GI19922364, Length=269, Percent_Identity=40.5204460966543, Blast_Score=203, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51047; Mature: 50916

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRIFDTGTRTLRDFKPVQPGHASVYLCGATPQSSPHIGHVRSAVAFDILRRWLMAKGL
CEEEEEECCCHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
DVAFVRNVTDIDDKILTKASENGRPWWEWVSTYEREFTWTYNTLGVLPPSTEPRATGHVT
CEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEECEEECCCCCCCCCCCHHHH
QMIKYMQRLIDNGFAYAVDGSVYFDVAAWSKAEGSDYGSLSGNRVEDMEQGEPDNFGKRG
HHHHHHHHHHCCCCEEEECCEEEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
PQDFALWKAAKPGEPSWPTPWGDGRPGWHLECSAMATYYLGEQFDIHCGGLDLQFPHHEN
CCHHHHEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEEECCEEEECCCCCH
EIAQAHAAGDKFANYWMHNHWVTMAGEKMSKSLGNVLAVPEMLKQVRPVELRYYLGSAHY
HHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
RSVLEYSESALSEAAVGYRRIESFLERVGDVEVGEWTPGFEVAMDEDIAVPKALAEIHNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
VREGNAALDKGDREAAEKLASSVRAMTGVLGFDPVEWGSDAGADGKADKALDVLISSELE
HHCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RRATARAEKNWAVADEVRDRLADAGIEVVDTADGATWKLQ
HHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCEEEEC
>Mature Secondary Structure 
TLRIFDTGTRTLRDFKPVQPGHASVYLCGATPQSSPHIGHVRSAVAFDILRRWLMAKGL
EEEEEECCCHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
DVAFVRNVTDIDDKILTKASENGRPWWEWVSTYEREFTWTYNTLGVLPPSTEPRATGHVT
CEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEECEEECCCCCCCCCCCHHHH
QMIKYMQRLIDNGFAYAVDGSVYFDVAAWSKAEGSDYGSLSGNRVEDMEQGEPDNFGKRG
HHHHHHHHHHCCCCEEEECCEEEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
PQDFALWKAAKPGEPSWPTPWGDGRPGWHLECSAMATYYLGEQFDIHCGGLDLQFPHHEN
CCHHHHEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEEECCEEEECCCCCH
EIAQAHAAGDKFANYWMHNHWVTMAGEKMSKSLGNVLAVPEMLKQVRPVELRYYLGSAHY
HHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
RSVLEYSESALSEAAVGYRRIESFLERVGDVEVGEWTPGFEVAMDEDIAVPKALAEIHNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
VREGNAALDKGDREAAEKLASSVRAMTGVLGFDPVEWGSDAGADGKADKALDVLISSELE
HHCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RRATARAEKNWAVADEVRDRLADAGIEVVDTADGATWKLQ
HHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA