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The map label for this gene is iolG3 [H]

Identifier: 62391475

GI number: 62391475

Start: 2777982

End: 2778419

Strand: Reverse

Name: iolG3 [H]

Synonym: cg2919

Alternate gene names: 62391475

Gene position: 2778419-2777982 (Counterclockwise)

Preceding gene: 62391476

Following gene: 62391474

Centisome position: 84.64

GC content: 57.31

Gene sequence:

>438_bases
ATGTCTGACAAGATCTGGAAAGTCGGCATCATCGGTTGCGGTGCAATCAGCCGAAACCATATCGAAGCAGTTCAGGCAAT
CCCCGGCGCAGAAGTCAGCGCAGTCTGTGATGTGGATGGTGCGAAAGCATCGGAAACCGCAGCGAAATATGGAATTTCTC
CCAGTTTCACGTCTGTCGATGAGATCCTCGCCTCCGGGGTGGACATTGTCGCAGTCTGCACCCCACATCCAACCCACGAA
ACAGTGGTCCTCGCCGCTGCTGCCGCCGGAGTGCACGTGCTTTGTGAGAAGCCAATCGCCATCGAACTCGATTCCGCACA
GCGCATGATCGATGCCTGCGAGTCCGCAGGGGTCCAACTTGGCGTGCTCTTCCAGCGCCGCTTCTGGCCCGCGGCTCAAA
AAATGAAAAAGGAGCCGTCATGGGCCAATGCACGGTAG

Upstream 100 bases:

>100_bases
TTGCGGGATTCATCATCGGCGCAATCGCACTGTCTGCCGCAGTTATTTTGACCACCAAGGAAACCGCCTTCACCAAGCTT
GAAGATCTAGGGAAGAAATA

Downstream 100 bases:

>100_bases
CGCTTTACCGAGAGCATTCCTATTACACAGCAACCCCATGGCGAGGAACCTGGGCAGCCGATGGCGGTGGAGTGCTCATG
ACTCAAGCCATCCACTACAT

Product: oxidoreductase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase 3; MI 2-dehydrogenase 3 [H]

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MSDKIWKVGIIGCGAISRNHIEAVQAIPGAEVSAVCDVDGAKASETAAKYGISPSFTSVDEILASGVDIVAVCTPHPTHE
TVVLAAAAAGVHVLCEKPIAIELDSAQRMIDACESAGVQLGVLFQRRFWPAAQKMKKEPSWANAR

Sequences:

>Translated_145_residues
MSDKIWKVGIIGCGAISRNHIEAVQAIPGAEVSAVCDVDGAKASETAAKYGISPSFTSVDEILASGVDIVAVCTPHPTHE
TVVLAAAAAGVHVLCEKPIAIELDSAQRMIDACESAGVQLGVLFQRRFWPAAQKMKKEPSWANAR
>Mature_144_residues
SDKIWKVGIIGCGAISRNHIEAVQAIPGAEVSAVCDVDGAKASETAAKYGISPSFTSVDEILASGVDIVAVCTPHPTHET
VVLAAAAAGVHVLCEKPIAIELDSAQRMIDACESAGVQLGVLFQRRFWPAAQKMKKEPSWANAR

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=131, Percent_Identity=31.2977099236641, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1787574, Length=140, Percent_Identity=32.1428571428571, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581117, Length=137, Percent_Identity=31.3868613138686, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 15226; Mature: 15094

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKIWKVGIIGCGAISRNHIEAVQAIPGAEVSAVCDVDGAKASETAAKYGISPSFTSVD
CCCCEEEEEEEECCCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCHHHH
EILASGVDIVAVCTPHPTHETVVLAAAAAGVHVLCEKPIAIELDSAQRMIDACESAGVQL
HHHHCCCCEEEEECCCCCCCEEEEEEHHCCEEEEECCCEEEEECHHHHHHHHHHHCCCEE
GVLFQRRFWPAAQKMKKEPSWANAR
EEHHHHHCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDKIWKVGIIGCGAISRNHIEAVQAIPGAEVSAVCDVDGAKASETAAKYGISPSFTSVD
CCCEEEEEEEECCCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCHHHH
EILASGVDIVAVCTPHPTHETVVLAAAAAGVHVLCEKPIAIELDSAQRMIDACESAGVQL
HHHHCCCCEEEEECCCCCCCEEEEEEHHCCEEEEECCCEEEEECHHHHHHHHHHHCCCEE
GVLFQRRFWPAAQKMKKEPSWANAR
EEHHHHHCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA