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The map label for this gene is cgtS3 [H]

Identifier: 62391445

GI number: 62391445

Start: 2745950

End: 2747407

Strand: Reverse

Name: cgtS3 [H]

Synonym: cg2887

Alternate gene names: 62391445

Gene position: 2747407-2745950 (Counterclockwise)

Preceding gene: 62391446

Following gene: 62391442

Centisome position: 83.69

GC content: 55.21

Gene sequence:

>1458_bases
ATGGAAAATCCTTATGTTGCTGCGCTCGATGACGAAAACCAAGAAGTCGGCGTAAAAAAAGAAGCAGAAAAAGAACCTGA
AATAGGTCCCATCAGAGCTGCCGGACGAGCCATACCGCTGCGCACCCGCATCATTTTGATCGTGGTGGGTATCGCCGGGC
TTGGTTTGCTGGTCAACGCGATTGCTGTCTCCAGCCTCATGCGTGAAGTTTCCTATACCCGCATGGATCAAGAGCTAGAG
ACCTCGATGGGGACGTGGGCGCATAACGTTGAGCTGTTTAATTTCGATGGCGTCCGCCAAGGGCCACCCAGCGATTATTA
TGTGGCCAAGGTTTTTCCTGATGGATCCAGCATCATCTTCAACGATGCACAATCGGCACCCGATCTAGCTGAAACCACCA
TCGGTACTGGTCCACACACTGTGGATGCTGCTAGCGGTTCTGCCTCCAACACTCCGTGGCGTGTGATGGCGGAAAAGAAC
GGTGACATTATCACCGTGGTGGGTAAAAGCATGGGGCGTGAAACAAACCTGCTGTACCGATTGGTGATGGTGCAGATGAT
CATCGGCGCGCTGATTCTGGTTGCTATTTTGATTACTTCACTCTTCCTAGTCAGACGCTCGTTGCGGCCGTTGAGAGAAG
TTGAAGAGACCGCCACCAGGATTGCGGGCGGTGATTTGGATCGACGTGTCCCGCAGTGGCCAATGACCACAGAAGTCGGA
CAGCTGTCGAATGCCCTCAATATCATGTTGGAGCAGCTCCAAGCCTCAATTCTGACCGCCCAGCAAAAAGAAGCTCAGAT
GCGCCGATTCGTTGGCGATGCCTCCCACGAGCTCCGCACACCACTGACCTCTGTGAAGGGCTTCACCGAGCTGTATTCAT
CAGGTGCAACAGATGATGCCAACTGGGTCATGTCCAAGATCGGTGGCGAAGCCCAACGCATGAGTGTGCTTGTGGAAGAC
CTCCTGTCACTGACGCGTGCCGAAGGCCAGCAAATGGAGAAGCACCGCGTTGACGTGCTGGAACTCGCCTTGGCAGTACG
CGGATCCATGCGAGCAGCCTGGCCAGATCGCACAGTCAATGTATCCAACAAAGCTGAGTCCATTCCGGTTGTCAAAGGCG
ACCCAACTCGCCTCCACCAAGTGCTTACCAACCTGGTTGCCAACGGACTAAACCACGGCGGACCGGACGCGGAAGTCAGC
ATTGAGATCAACACCGATGGACAAAACGTGAGGATTCTCGTGGCAGACAACGGTGTCGGAATGTCTGAAGAAGATGCTCA
GCATATCTTCGAGCGTTTCTACCGCGCCGATTCCTCCCGCTCACGCGCATCCGGCGGATCGGGCCTCGGCCTTGCGATCA
CGAAATCCCTGGTCGAAGGCCACGGCGGCACAGTCACCGTCGACAGCGTGCAAGGCGAAGGCACGGTGTTCACGATCACC
TTGCCGGCGGTTTCTTAA

Upstream 100 bases:

>100_bases
CCTACCTGCGCCGCAAGGTGGACACCCAGGATCCGCAGCTAATTCAGACTGTTCGTGGCGTTGGATATGTTCTGCGCACC
CCACGTAGCTAAATTCTCCT

Downstream 100 bases:

>100_bases
AGGCATCAAGGGCCGGAAAAGATTGCTTTTCGACGAACCCCTCCACCCGTGACAACCCTTCCGGCAAAGCTCCCCAAAAG
GGCACGCCGGTGACTCTCTC

Product: two component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MENPYVAALDDENQEVGVKKEAEKEPEIGPIRAAGRAIPLRTRIILIVVGIAGLGLLVNAIAVSSLMREVSYTRMDQELE
TSMGTWAHNVELFNFDGVRQGPPSDYYVAKVFPDGSSIIFNDAQSAPDLAETTIGTGPHTVDAASGSASNTPWRVMAEKN
GDIITVVGKSMGRETNLLYRLVMVQMIIGALILVAILITSLFLVRRSLRPLREVEETATRIAGGDLDRRVPQWPMTTEVG
QLSNALNIMLEQLQASILTAQQKEAQMRRFVGDASHELRTPLTSVKGFTELYSSGATDDANWVMSKIGGEAQRMSVLVED
LLSLTRAEGQQMEKHRVDVLELALAVRGSMRAAWPDRTVNVSNKAESIPVVKGDPTRLHQVLTNLVANGLNHGGPDAEVS
IEINTDGQNVRILVADNGVGMSEEDAQHIFERFYRADSSRSRASGGSGLGLAITKSLVEGHGGTVTVDSVQGEGTVFTIT
LPAVS

Sequences:

>Translated_485_residues
MENPYVAALDDENQEVGVKKEAEKEPEIGPIRAAGRAIPLRTRIILIVVGIAGLGLLVNAIAVSSLMREVSYTRMDQELE
TSMGTWAHNVELFNFDGVRQGPPSDYYVAKVFPDGSSIIFNDAQSAPDLAETTIGTGPHTVDAASGSASNTPWRVMAEKN
GDIITVVGKSMGRETNLLYRLVMVQMIIGALILVAILITSLFLVRRSLRPLREVEETATRIAGGDLDRRVPQWPMTTEVG
QLSNALNIMLEQLQASILTAQQKEAQMRRFVGDASHELRTPLTSVKGFTELYSSGATDDANWVMSKIGGEAQRMSVLVED
LLSLTRAEGQQMEKHRVDVLELALAVRGSMRAAWPDRTVNVSNKAESIPVVKGDPTRLHQVLTNLVANGLNHGGPDAEVS
IEINTDGQNVRILVADNGVGMSEEDAQHIFERFYRADSSRSRASGGSGLGLAITKSLVEGHGGTVTVDSVQGEGTVFTIT
LPAVS
>Mature_485_residues
MENPYVAALDDENQEVGVKKEAEKEPEIGPIRAAGRAIPLRTRIILIVVGIAGLGLLVNAIAVSSLMREVSYTRMDQELE
TSMGTWAHNVELFNFDGVRQGPPSDYYVAKVFPDGSSIIFNDAQSAPDLAETTIGTGPHTVDAASGSASNTPWRVMAEKN
GDIITVVGKSMGRETNLLYRLVMVQMIIGALILVAILITSLFLVRRSLRPLREVEETATRIAGGDLDRRVPQWPMTTEVG
QLSNALNIMLEQLQASILTAQQKEAQMRRFVGDASHELRTPLTSVKGFTELYSSGATDDANWVMSKIGGEAQRMSVLVED
LLSLTRAEGQQMEKHRVDVLELALAVRGSMRAAWPDRTVNVSNKAESIPVVKGDPTRLHQVLTNLVANGLNHGGPDAEVS
IEINTDGQNVRILVADNGVGMSEEDAQHIFERFYRADSSRSRASGGSGLGLAITKSLVEGHGGTVTVDSVQGEGTVFTIT
LPAVS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=315, Percent_Identity=32.6984126984127, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788393, Length=279, Percent_Identity=32.9749103942652, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=32.034632034632, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1787894, Length=312, Percent_Identity=29.4871794871795, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790346, Length=280, Percent_Identity=31.4285714285714, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789149, Length=339, Percent_Identity=29.7935103244838, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788713, Length=279, Percent_Identity=29.0322580645161, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=28.2700421940928, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=27.2, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=31.5789473684211, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788279, Length=322, Percent_Identity=26.7080745341615, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=29.0178571428571, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081816, Length=335, Percent_Identity=25.9701492537313, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789403, Length=457, Percent_Identity=24.72647702407, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=28.3842794759825, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=255, Percent_Identity=28.2352941176471, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789808, Length=295, Percent_Identity=26.4406779661017, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790300, Length=269, Percent_Identity=29.368029739777, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=25.2136752136752, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790551, Length=296, Percent_Identity=27.7027027027027, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52366; Mature: 52366

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENPYVAALDDENQEVGVKKEAEKEPEIGPIRAAGRAIPLRTRIILIVVGIAGLGLLVNA
CCCCEEEEECCCCCCCCCCHHHCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
IAVSSLMREVSYTRMDQELETSMGTWAHNVELFNFDGVRQGPPSDYYVAKVFPDGSSIIF
HHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEEECCCCCCCCCCCEEEEEEECCCCEEEE
NDAQSAPDLAETTIGTGPHTVDAASGSASNTPWRVMAEKNGDIITVVGKSMGRETNLLYR
ECCCCCCCHHHHHCCCCCCEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHH
LVMVQMIIGALILVAILITSLFLVRRSLRPLREVEETATRIAGGDLDRRVPQWPMTTEVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHH
QLSNALNIMLEQLQASILTAQQKEAQMRRFVGDASHELRTPLTSVKGFTELYSSGATDDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHCCCCCHH
NWVMSKIGGEAQRMSVLVEDLLSLTRAEGQQMEKHRVDVLELALAVRGSMRAAWPDRTVN
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
VSNKAESIPVVKGDPTRLHQVLTNLVANGLNHGGPDAEVSIEINTDGQNVRILVADNGVG
CCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEECCCCC
MSEEDAQHIFERFYRADSSRSRASGGSGLGLAITKSLVEGHGGTVTVDSVQGEGTVFTIT
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEE
LPAVS
ECCCC
>Mature Secondary Structure
MENPYVAALDDENQEVGVKKEAEKEPEIGPIRAAGRAIPLRTRIILIVVGIAGLGLLVNA
CCCCEEEEECCCCCCCCCCHHHCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
IAVSSLMREVSYTRMDQELETSMGTWAHNVELFNFDGVRQGPPSDYYVAKVFPDGSSIIF
HHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEEECCCCCCCCCCCEEEEEEECCCCEEEE
NDAQSAPDLAETTIGTGPHTVDAASGSASNTPWRVMAEKNGDIITVVGKSMGRETNLLYR
ECCCCCCCHHHHHCCCCCCEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHH
LVMVQMIIGALILVAILITSLFLVRRSLRPLREVEETATRIAGGDLDRRVPQWPMTTEVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHH
QLSNALNIMLEQLQASILTAQQKEAQMRRFVGDASHELRTPLTSVKGFTELYSSGATDDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHCCCCCHH
NWVMSKIGGEAQRMSVLVEDLLSLTRAEGQQMEKHRVDVLELALAVRGSMRAAWPDRTVN
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
VSNKAESIPVVKGDPTRLHQVLTNLVANGLNHGGPDAEVSIEINTDGQNVRILVADNGVG
CCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEECCCCC
MSEEDAQHIFERFYRADSSRSRASGGSGLGLAITKSLVEGHGGTVTVDSVQGEGTVFTIT
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEE
LPAVS
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]