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The map label for this gene is murA2 [H]

Identifier: 62391397

GI number: 62391397

Start: 2690104

End: 2691369

Strand: Reverse

Name: murA2 [H]

Synonym: cg2829

Alternate gene names: 62391397

Gene position: 2691369-2690104 (Counterclockwise)

Preceding gene: 62391399

Following gene: 62391396

Centisome position: 81.99

GC content: 53.95

Gene sequence:

>1266_bases
GTGGGGCACGTGAAAGACAAGTTTTTAGTCACTGGTGGAGCACAGCTGCAGGGCGCTGTAAAAGTTTACGGCGCAAAAAA
CAGCGTTTTGAAGCTCATGGCAGCAGCACTTCTCGCTGAAGGCACAACAACTCTAACCAATTGCCCCGAAATCCTCGACG
TCCCCCTGATGCGCGACGTCCTCGTTGGTCTTGGCTGCGATGTCACCATCGACGGCTCAACCGTAACCATTACTACCCCT
GCAGAACTCAGCTCCAATGCTGACTTCCCAGCAGTCACCCAATTCCGTGCATCCGTATGTGTGCTTGGTCCATTGACAGC
ACGTTGTGGTCGCGCAGTTGTATCCCTTCCCGGCGGTGACGCCATTGGATCCCGTCCACTCGACATGCATCAAAGCGGCC
TGGAAAAGCTTGGTGCCACCACCCGCATTTCCCACGGTGCAGTAGTTGCAGAAGCTGAAAAGCTCGTCGGTGCCAACATC
ACCCTGGATTTCCCGTCCGTCGGCGCCACCGAAAACATCCTCACTGCATCCGTCATGGCAGAAGGACGCACAGTATTAGA
TAACGCAGCGCGCGAACCAGAAATTGTTGATCTCTGCCGTATGCTTCGATCCATGGGCGCCAACATTGAAGGTGAAGGAA
GCCCAACCATCACCATCGAAGGCGTAGAGAAACTCACCCCAACTCAGCACGAAGTAATCGGCGACCGCATCGTTGCCGGA
ACGTGGGCATACGCCGCTGCGATGACTCGTGGCGATATTACAGTTGGCGGAATCGCACCAAGGTATCTGCACCTTCCATT
GGAAAAGCTCAAGATCGCCGGCGCCAAGGTGGAAACCTACGAAAACGGCTTCCGCGTCCAAATGGATAAGCAGCCTGAGG
CAACCGACTACCAAACCCTCCCGTTCCCAGGGTTCCCTACAGATCTGCAACCCATGGCAATTGGAATCAACGCAGTATCT
AATGGAACTTCAGTAATTACAGAGAATGTCTTTGAATCACGATTCCGCTTCGTCGATGAAATGCTTCGCCTGGGCGCTGA
CGCGAATGTCGATGGGCACCACGTAGTAATCCGAGGAATTGAACAGCTTTCCTCTACTTCCGTGTGGTCTTCAGATATCC
GTGCAGGAGCAGGACTGGTTCTTGCCGCCCTTTGCGCAGACGGAGTGACCGAAGTTCACGATGTTTTCCACATCGACCGC
GGATACCCCAACTTCGTGGAAAATCTGCAGAAACTCGGAGCGACCATCGAAAGGGTTTCTTCCTAA

Upstream 100 bases:

>100_bases
TTCCATCGTCCCCGGTTCGCGTATAGATCTTGGTTAAATGAACGGCCATAACTTGAGATTCTAGCTGTCGTTACGCACAG
GGGTGGGGAACACGGATAAG

Downstream 100 bases:

>100_bases
CGAAGCCTTCCCATCAAGCATCCCCCAGCGAAACCATCATTGAGCTGGGGGTTTGTGCTTGTCAGAGGGGCTGTGTAGAT
TAATTCGAGTCAGCGCAACG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MGHVKDKFLVTGGAQLQGAVKVYGAKNSVLKLMAAALLAEGTTTLTNCPEILDVPLMRDVLVGLGCDVTIDGSTVTITTP
AELSSNADFPAVTQFRASVCVLGPLTARCGRAVVSLPGGDAIGSRPLDMHQSGLEKLGATTRISHGAVVAEAEKLVGANI
TLDFPSVGATENILTASVMAEGRTVLDNAAREPEIVDLCRMLRSMGANIEGEGSPTITIEGVEKLTPTQHEVIGDRIVAG
TWAYAAAMTRGDITVGGIAPRYLHLPLEKLKIAGAKVETYENGFRVQMDKQPEATDYQTLPFPGFPTDLQPMAIGINAVS
NGTSVITENVFESRFRFVDEMLRLGADANVDGHHVVIRGIEQLSSTSVWSSDIRAGAGLVLAALCADGVTEVHDVFHIDR
GYPNFVENLQKLGATIERVSS

Sequences:

>Translated_421_residues
MGHVKDKFLVTGGAQLQGAVKVYGAKNSVLKLMAAALLAEGTTTLTNCPEILDVPLMRDVLVGLGCDVTIDGSTVTITTP
AELSSNADFPAVTQFRASVCVLGPLTARCGRAVVSLPGGDAIGSRPLDMHQSGLEKLGATTRISHGAVVAEAEKLVGANI
TLDFPSVGATENILTASVMAEGRTVLDNAAREPEIVDLCRMLRSMGANIEGEGSPTITIEGVEKLTPTQHEVIGDRIVAG
TWAYAAAMTRGDITVGGIAPRYLHLPLEKLKIAGAKVETYENGFRVQMDKQPEATDYQTLPFPGFPTDLQPMAIGINAVS
NGTSVITENVFESRFRFVDEMLRLGADANVDGHHVVIRGIEQLSSTSVWSSDIRAGAGLVLAALCADGVTEVHDVFHIDR
GYPNFVENLQKLGATIERVSS
>Mature_420_residues
GHVKDKFLVTGGAQLQGAVKVYGAKNSVLKLMAAALLAEGTTTLTNCPEILDVPLMRDVLVGLGCDVTIDGSTVTITTPA
ELSSNADFPAVTQFRASVCVLGPLTARCGRAVVSLPGGDAIGSRPLDMHQSGLEKLGATTRISHGAVVAEAEKLVGANIT
LDFPSVGATENILTASVMAEGRTVLDNAAREPEIVDLCRMLRSMGANIEGEGSPTITIEGVEKLTPTQHEVIGDRIVAGT
WAYAAAMTRGDITVGGIAPRYLHLPLEKLKIAGAKVETYENGFRVQMDKQPEATDYQTLPFPGFPTDLQPMAIGINAVSN
GTSVITENVFESRFRFVDEMLRLGADANVDGHHVVIRGIEQLSSTSVWSSDIRAGAGLVLAALCADGVTEVHDVFHIDRG
YPNFVENLQKLGATIERVSS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=45.5635491606715, Blast_Score=330, Evalue=1e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44491; Mature: 44360

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHVKDKFLVTGGAQLQGAVKVYGAKNSVLKLMAAALLAEGTTTLTNCPEILDVPLMRDV
CCCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHH
LVGLGCDVTIDGSTVTITTPAELSSNADFPAVTQFRASVCVLGPLTARCGRAVVSLPGGD
HHHCCCCEEECCCEEEEECCHHCCCCCCCCHHHHHHHCEEEECCHHHHHCCEEEECCCCC
AIGSRPLDMHQSGLEKLGATTRISHGAVVAEAEKLVGANITLDFPSVGATENILTASVMA
CCCCCCCHHHHHHHHHHCCCCEECCCCCEEEHHHHHCCEEEEECCCCCCCHHHHHHHHHH
EGRTVLDNAAREPEIVDLCRMLRSMGANIEGEGSPTITIEGVEKLTPTQHEVIGDRIVAG
CCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHCCCCHHHHHCCHHEEC
TWAYAAAMTRGDITVGGIAPRYLHLPLEKLKIAGAKVETYENGFRVQMDKQPEATDYQTL
HHHHHHHHHCCCEEECCCCCHHHHCCHHHHHCCCCEEEECCCCEEEEECCCCCCCCCEEC
PFPGFPTDLQPMAIGINAVSNGTSVITENVFESRFRFVDEMLRLGADANVDGHHVVIRGI
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEH
EQLSSTSVWSSDIRAGAGLVLAALCADGVTEVHDVFHIDRGYPNFVENLQKLGATIERVS
HHHHCCCCCHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
S
C
>Mature Secondary Structure 
GHVKDKFLVTGGAQLQGAVKVYGAKNSVLKLMAAALLAEGTTTLTNCPEILDVPLMRDV
CCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHH
LVGLGCDVTIDGSTVTITTPAELSSNADFPAVTQFRASVCVLGPLTARCGRAVVSLPGGD
HHHCCCCEEECCCEEEEECCHHCCCCCCCCHHHHHHHCEEEECCHHHHHCCEEEECCCCC
AIGSRPLDMHQSGLEKLGATTRISHGAVVAEAEKLVGANITLDFPSVGATENILTASVMA
CCCCCCCHHHHHHHHHHCCCCEECCCCCEEEHHHHHCCEEEEECCCCCCCHHHHHHHHHH
EGRTVLDNAAREPEIVDLCRMLRSMGANIEGEGSPTITIEGVEKLTPTQHEVIGDRIVAG
CCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHCCCCHHHHHCCHHEEC
TWAYAAAMTRGDITVGGIAPRYLHLPLEKLKIAGAKVETYENGFRVQMDKQPEATDYQTL
HHHHHHHHHCCCEEECCCCCHHHHCCHHHHHCCCCEEEECCCCEEEEECCCCCCCCCEEC
PFPGFPTDLQPMAIGINAVSNGTSVITENVFESRFRFVDEMLRLGADANVDGHHVVIRGI
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEH
EQLSSTSVWSSDIRAGAGLVLAALCADGVTEVHDVFHIDRGYPNFVENLQKLGATIERVS
HHHHCCCCCHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]