Click here to switch to the map view.

The map label for this gene is yhdH [H]

Identifier: 62391376

GI number: 62391376

Start: 2655298

End: 2656320

Strand: Reverse

Name: yhdH [H]

Synonym: cg2795

Alternate gene names: 62391376

Gene position: 2656320-2655298 (Counterclockwise)

Preceding gene: 62391379

Following gene: 62391375

Centisome position: 80.92

GC content: 54.55

Gene sequence:

>1023_bases
ATGACTCCAGCTCACATATTTTCTGAAGGTCCAATCAATAGTGTTGTTCTCAGCCAGGATGAGGATGGAAATTTCACCAC
CTCCTACCAGGACACGTTCTCTGATCCATCATTTTTGGGGGAAGGTGACGTTCTAATTGAGGTTGGTTGGTCCAGCTTGA
ATTACAAGGACGCAATGGCTCTGAAGGGTGATAAGGGAGTGGTGCGTACTGTGCCACTGATTCCAGGTATCGATGTGGTG
GGCACTGTGATCGAGAGCGCTGATCCTCGCTTTGGTCGTGGTGATGAAGTGGTGCTGAATGGCGCTGGTTTGGGGGAGAA
CCGGCATGGAGGTTTCACGCAGCGGCTGAAAGTGCCGTCTGAACCGTTGCTGCATATTCCATTTAACTTCTCCGCGCAGC
AGGTGGGTGCGTTGGGTACTGCAGGTTTCACGGCTGCGCTATCGGTGAATGCTCTGGTCGATCAAGGTATCAAACCGGAG
GATGGGGAGATTCTGGTAACTGGTTCGACTGGTGGTGTGGGTTCGATTGCACTTCACCTGCTGAATAAGTTGGGATATAC
GACGGTCGCGGTGACGGGGCGTCGAGAAGCGCATGCCGAATACCTGACCAGCCTGGGCGCAAGCGACATCATTGATCGCG
CGGAGCTTTCTGAAAAGGGCCGGCCGCTGCAGAAGGGGCGTTGGGCGGGTGTAGTGGATTCAGTGGGATCCCACACACTT
GTCAATGCGATTGCTCAGACAAAATGGGGCGGAATTGTCACGGCGTGTGGCATGGCTCAGGGGCCGGATCTGCCGGGAAC
GGTGTTGCCGTTTATTCTTCGTGGCGTGCATTTGGTTGGCATTAACTCTGTCGATGCACCCCGTGAGCTGCGTCGACGTG
CGTGGGCGTTGCTGTCCGAGCATCTTGATACCGCGGTGCTAGATGATATGACCACTGTGATTGATGTCAAGGATGTTGCT
CAAGCTGGCGAAGATTTGATGGCTGGCAAGCTTCACGGACGTACCGCGGTGCGTGTTCATTAG

Upstream 100 bases:

>100_bases
TCCTCCCATTAAGCACCTTGTCTTCCGGAAGCTTCCACCCCAAATTCCAAACCCCAAATTCCATGCCCCGGATGGACATT
TTTCATTACACTCGGGGGCT

Downstream 100 bases:

>100_bases
CAGGTCAAGCGCGTAATTGAGGGCTAGACTGGTTAGTACCGGATATTCTTTTTTTCTTTAGTTTGTGGGAGTGGAGATAA
CTATGGACAATCCAGTCAAC

Product: NADPH quinone reductase or related Zn-dependent oxidoreductase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTPAHIFSEGPINSVVLSQDEDGNFTTSYQDTFSDPSFLGEGDVLIEVGWSSLNYKDAMALKGDKGVVRTVPLIPGIDVV
GTVIESADPRFGRGDEVVLNGAGLGENRHGGFTQRLKVPSEPLLHIPFNFSAQQVGALGTAGFTAALSVNALVDQGIKPE
DGEILVTGSTGGVGSIALHLLNKLGYTTVAVTGRREAHAEYLTSLGASDIIDRAELSEKGRPLQKGRWAGVVDSVGSHTL
VNAIAQTKWGGIVTACGMAQGPDLPGTVLPFILRGVHLVGINSVDAPRELRRRAWALLSEHLDTAVLDDMTTVIDVKDVA
QAGEDLMAGKLHGRTAVRVH

Sequences:

>Translated_340_residues
MTPAHIFSEGPINSVVLSQDEDGNFTTSYQDTFSDPSFLGEGDVLIEVGWSSLNYKDAMALKGDKGVVRTVPLIPGIDVV
GTVIESADPRFGRGDEVVLNGAGLGENRHGGFTQRLKVPSEPLLHIPFNFSAQQVGALGTAGFTAALSVNALVDQGIKPE
DGEILVTGSTGGVGSIALHLLNKLGYTTVAVTGRREAHAEYLTSLGASDIIDRAELSEKGRPLQKGRWAGVVDSVGSHTL
VNAIAQTKWGGIVTACGMAQGPDLPGTVLPFILRGVHLVGINSVDAPRELRRRAWALLSEHLDTAVLDDMTTVIDVKDVA
QAGEDLMAGKLHGRTAVRVH
>Mature_339_residues
TPAHIFSEGPINSVVLSQDEDGNFTTSYQDTFSDPSFLGEGDVLIEVGWSSLNYKDAMALKGDKGVVRTVPLIPGIDVVG
TVIESADPRFGRGDEVVLNGAGLGENRHGGFTQRLKVPSEPLLHIPFNFSAQQVGALGTAGFTAALSVNALVDQGIKPED
GEILVTGSTGGVGSIALHLLNKLGYTTVAVTGRREAHAEYLTSLGASDIIDRAELSEKGRPLQKGRWAGVVDSVGSHTLV
NAIAQTKWGGIVTACGMAQGPDLPGTVLPFILRGVHLVGINSVDAPRELRRRAWALLSEHLDTAVLDDMTTVIDVKDVAQ
AGEDLMAGKLHGRTAVRVH

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789651, Length=325, Percent_Identity=47.0769230769231, Blast_Score=285, Evalue=4e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 35841; Mature: 35710

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAHIFSEGPINSVVLSQDEDGNFTTSYQDTFSDPSFLGEGDVLIEVGWSSLNYKDAMA
CCCCCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHEE
LKGDKGVVRTVPLIPGIDVVGTVIESADPRFGRGDEVVLNGAGLGENRHGGFTQRLKVPS
ECCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCCC
EPLLHIPFNFSAQQVGALGTAGFTAALSVNALVDQGIKPEDGEILVTGSTGGVGSIALHL
CCEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHH
LNKLGYTTVAVTGRREAHAEYLTSLGASDIIDRAELSEKGRPLQKGRWAGVVDSVGSHTL
HHHCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHH
VNAIAQTKWGGIVTACGMAQGPDLPGTVLPFILRGVHLVGINSVDAPRELRRRAWALLSE
HHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHH
HLDTAVLDDMTTVIDVKDVAQAGEDLMAGKLHGRTAVRVH
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEC
>Mature Secondary Structure 
TPAHIFSEGPINSVVLSQDEDGNFTTSYQDTFSDPSFLGEGDVLIEVGWSSLNYKDAMA
CCCCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHEE
LKGDKGVVRTVPLIPGIDVVGTVIESADPRFGRGDEVVLNGAGLGENRHGGFTQRLKVPS
ECCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCCC
EPLLHIPFNFSAQQVGALGTAGFTAALSVNALVDQGIKPEDGEILVTGSTGGVGSIALHL
CCEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHH
LNKLGYTTVAVTGRREAHAEYLTSLGASDIIDRAELSEKGRPLQKGRWAGVVDSVGSHTL
HHHCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHH
VNAIAQTKWGGIVTACGMAQGPDLPGTVLPFILRGVHLVGINSVDAPRELRRRAWALLSE
HHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHH
HLDTAVLDDMTTVIDVKDVAQAGEDLMAGKLHGRTAVRVH
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370469; 9278503 [H]