Click here to switch to the map view.

The map label for this gene is fes [H]

Identifier: 62391313

GI number: 62391313

Start: 2591212

End: 2592456

Strand: Reverse

Name: fes [H]

Synonym: cg2719

Alternate gene names: 62391313

Gene position: 2592456-2591212 (Counterclockwise)

Preceding gene: 62391314

Following gene: 62391309

Centisome position: 78.97

GC content: 60.48

Gene sequence:

>1245_bases
ATGCCACCGTTGAGGCAGACAAAAACGTGGGTGGACCGCAATGGGTCCGCTCATGTGGAGTTGTCGCCAACCGTGCCACC
GCAAACCCCCAAACGTCACATGCGCATCCAAAGCCCCATGGAAATTTCCTGGAGTGAAGCGGTGCGCGAAGGCGGGGAGC
ATTCCGCTCGCCGCTGTGGTGACATGGCTGTGTCCGCGTTGGCTAAGCCGAATCCCATCATTGACGATGATCCGGAAGGC
AACCCCGATGTTTGCATGTATACCTGGATCGTTGAGTGTCCCGGCGCTACCGCAGTGCTGCTATGGATCAATGGGGTTTT
TGATCACGAGCGCATTGAAGAATCTGAAATGACCCGCCTCGAGGGCTCTGATCTGTGGATTCTCAGCTTGCGTATGCCTT
CCGATTGGCGAGCCAGCTACACCGTCAACGCCTGGTCTGGCGACGGGGTTGCGCCATGGCGTGAGGCGGGCGATCGGATG
CATATCCGCAAAGCCGCGATGTCGGGTGGGCGTCCGGATTCCCGCGCGATGGGTCATATCATGGATTCCTCGCTCGTTGA
AGGCCCTGATGCGTTGCCGGACTGCTGGGTTGCGGCGTCGACAAGCGTAAAAGTCGTGGAAGAAACCGTCGCCGGCGAGC
ATTTCTGGTTCTATGAGGCGCCGGTCAAGGCGCCGCTGCTGGTGCTGTTTGATGGCCAACACTGGAACAACAGCATGAAT
CTGCCTGCGCAGGTCGATGCGGCCATCGCCATCGGCTTGCTGCCGCCGGTCAGCCTGCTCATGATCGATTCCGTCAACAC
CGAACGCCGCTGGGATAGTGTCGGCGTGCCAGGTGGGCAGGTTGATGTGCTTATCGACGCCCTCCTCCCGCACGTCCGCG
AAACCTACAACGTTTCCGCGCGCGGCGAAGACACCATTGTCACCGGTGCAAGCTTCGGCGGCCTGGCGTCCCTGTGGGCT
CTTGCGCTTTCCGACGGCGAAGTCGGCCACGCAATCGCGCAATCGCCAAGCCTGTGGCGCTTCAACGTTGCCGACGCGCT
TTCTGCAGCAGAGCAGTGGAGCTCAATCCACCTGCAAGCTGGAAAATACGAAGGTGAAATGCTGCGCCTGTCGCATCAGC
TCGCCGAAGATCTCTCCGGCGACATCCGCGAGGTTCGTGTGCGCGGCGTGCATGGCGGCCACGATTGGGCCTGGTGGCGG
GTGCATATGCTCACCGAACTCACCAGGCTGCTTAAAACCCTCTAA

Upstream 100 bases:

>100_bases
ACCGGCGGTCGTCTTCGTGGCAAGAAAGCGCGGAGTATGCCTGCCGGTTGCGCACGTTTAAAGCGAAATACATGTAATGA
CCAGGCCAAGGGGAAACTAG

Downstream 100 bases:

>100_bases
TCAAAGTAGGGTGCAAAACGGTCCACCGCTGCCTGCGCATCATCTGCGCACTGCTCAGAGGTAGGACCAGGCTCTGCAAC
AAAAAATGAGCGACGGTAGT

Product: hypothetical protein

Products: Fe [C]

Alternate protein names: Ferric enterobactin esterase [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MPPLRQTKTWVDRNGSAHVELSPTVPPQTPKRHMRIQSPMEISWSEAVREGGEHSARRCGDMAVSALAKPNPIIDDDPEG
NPDVCMYTWIVECPGATAVLLWINGVFDHERIEESEMTRLEGSDLWILSLRMPSDWRASYTVNAWSGDGVAPWREAGDRM
HIRKAAMSGGRPDSRAMGHIMDSSLVEGPDALPDCWVAASTSVKVVEETVAGEHFWFYEAPVKAPLLVLFDGQHWNNSMN
LPAQVDAAIAIGLLPPVSLLMIDSVNTERRWDSVGVPGGQVDVLIDALLPHVRETYNVSARGEDTIVTGASFGGLASLWA
LALSDGEVGHAIAQSPSLWRFNVADALSAAEQWSSIHLQAGKYEGEMLRLSHQLAEDLSGDIREVRVRGVHGGHDWAWWR
VHMLTELTRLLKTL

Sequences:

>Translated_414_residues
MPPLRQTKTWVDRNGSAHVELSPTVPPQTPKRHMRIQSPMEISWSEAVREGGEHSARRCGDMAVSALAKPNPIIDDDPEG
NPDVCMYTWIVECPGATAVLLWINGVFDHERIEESEMTRLEGSDLWILSLRMPSDWRASYTVNAWSGDGVAPWREAGDRM
HIRKAAMSGGRPDSRAMGHIMDSSLVEGPDALPDCWVAASTSVKVVEETVAGEHFWFYEAPVKAPLLVLFDGQHWNNSMN
LPAQVDAAIAIGLLPPVSLLMIDSVNTERRWDSVGVPGGQVDVLIDALLPHVRETYNVSARGEDTIVTGASFGGLASLWA
LALSDGEVGHAIAQSPSLWRFNVADALSAAEQWSSIHLQAGKYEGEMLRLSHQLAEDLSGDIREVRVRGVHGGHDWAWWR
VHMLTELTRLLKTL
>Mature_413_residues
PPLRQTKTWVDRNGSAHVELSPTVPPQTPKRHMRIQSPMEISWSEAVREGGEHSARRCGDMAVSALAKPNPIIDDDPEGN
PDVCMYTWIVECPGATAVLLWINGVFDHERIEESEMTRLEGSDLWILSLRMPSDWRASYTVNAWSGDGVAPWREAGDRMH
IRKAAMSGGRPDSRAMGHIMDSSLVEGPDALPDCWVAASTSVKVVEETVAGEHFWFYEAPVKAPLLVLFDGQHWNNSMNL
PAQVDAAIAIGLLPPVSLLMIDSVNTERRWDSVGVPGGQVDVLIDALLPHVRETYNVSARGEDTIVTGASFGGLASLWAL
ALSDGEVGHAIAQSPSLWRFNVADALSAAEQWSSIHLQAGKYEGEMLRLSHQLAEDLSGDIREVRVRGVHGGHDWAWWRV
HMLTELTRLLKTL

Specific function: Upon internalization, ferric enterobactin is processed via an exquisitely specific pathway that is dependent on FES activity, making iron available for metabolic use [H]

COG id: COG2382

COG function: function code P; Enterochelin esterase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fes family [H]

Homologues:

Organism=Escherichia coli, GI1786799, Length=348, Percent_Identity=24.7126436781609, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021764
- InterPro:   IPR000801
- InterPro:   IPR014756 [H]

Pfam domain/function: PF11806 DUF3327; PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 45648; Mature: 45517

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPLRQTKTWVDRNGSAHVELSPTVPPQTPKRHMRIQSPMEISWSEAVREGGEHSARRCG
CCCCCCCHHHHCCCCCEEEEECCCCCCCCCHHHEEECCCCCCCHHHHHHCCCCHHHHHHH
DMAVSALAKPNPIIDDDPEGNPDVCMYTWIVECPGATAVLLWINGVFDHERIEESEMTRL
HHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEECCCCHHHHCHHHHHEE
EGSDLWILSLRMPSDWRASYTVNAWSGDGVAPWREAGDRMHIRKAAMSGGRPDSRAMGHI
CCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHHH
MDSSLVEGPDALPDCWVAASTSVKVVEETVAGEHFWFYEAPVKAPLLVLFDGQHWNNSMN
HHHHHCCCCCCCCCCEEECCCCHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCC
LPAQVDAAIAIGLLPPVSLLMIDSVNTERRWDSVGVPGGQVDVLIDALLPHVRETYNVSA
CCCHHHHEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
RGEDTIVTGASFGGLASLWALALSDGEVGHAIAQSPSLWRFNVADALSAAEQWSSIHLQA
CCCCEEEECCCCCHHHHHHHHHCCCCCCCHHHHCCCCCEEEEHHHHHHHHHHHCEEEEEC
GKYEGEMLRLSHQLAEDLSGDIREVRVRGVHGGHDWAWWRVHMLTELTRLLKTL
CCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPLRQTKTWVDRNGSAHVELSPTVPPQTPKRHMRIQSPMEISWSEAVREGGEHSARRCG
CCCCCCHHHHCCCCCEEEEECCCCCCCCCHHHEEECCCCCCCHHHHHHCCCCHHHHHHH
DMAVSALAKPNPIIDDDPEGNPDVCMYTWIVECPGATAVLLWINGVFDHERIEESEMTRL
HHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEECCCCHHHHCHHHHHEE
EGSDLWILSLRMPSDWRASYTVNAWSGDGVAPWREAGDRMHIRKAAMSGGRPDSRAMGHI
CCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHHH
MDSSLVEGPDALPDCWVAASTSVKVVEETVAGEHFWFYEAPVKAPLLVLFDGQHWNNSMN
HHHHHCCCCCCCCCCEEECCCCHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCC
LPAQVDAAIAIGLLPPVSLLMIDSVNTERRWDSVGVPGGQVDVLIDALLPHVRETYNVSA
CCCHHHHEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
RGEDTIVTGASFGGLASLWALALSDGEVGHAIAQSPSLWRFNVADALSAAEQWSSIHLQA
CCCCEEEECCCCCHHHHHHHHHCCCCCCCHHHHCCCCCEEEEHHHHHHHHHHHCEEEEEC
GKYEGEMLRLSHQLAEDLSGDIREVRVRGVHGGHDWAWWRVHMLTELTRLLKTL
CCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrienterobactin [C]

Specific reaction: ferrienterobactin = Fe [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA