Click here to switch to the map view.

The map label for this gene is pcaB1 [H]

Identifier: 62391239

GI number: 62391239

Start: 2510289

End: 2511407

Strand: Reverse

Name: pcaB1 [H]

Synonym: cg2629

Alternate gene names: 62391239

Gene position: 2511407-2510289 (Counterclockwise)

Preceding gene: 62391240

Following gene: 62391238

Centisome position: 76.5

GC content: 60.14

Gene sequence:

>1119_bases
ATGAAACCCCATTTTTTGGACTCTAAATTGACCCGATCTTTATACTCCGACCTTGCTGGTAGTGGAGAACACCTCAGCAG
CCTTTCCGACGAGACTTTCCTAAAGAATCTTCTTGTCGTGGAGGCCGCTTTGGCGGTTGCAGCTGCCCCCGAGCACGCAG
CAATGGCGAAGGCCACCATTGATTCTTATCAGTTGGATGTGGAGGAGCTTTCCCGTCGCGCAGCCGAGGGCGGTAATCCG
CTCATTCCGCTGGTCACTGACCTCAAGGCCATCAATCCGGCAGGCATCCACATTGGCGCAACGAGCCAGGACATCATTGA
TTCTGCGTTAATGCTGTGCATGAAGGAAGGGGTGGGGGAGGTCGTCGACAAGCTTAAAAAGCTTGCGCGAGATTTGGCCG
AGCTCACCGCGGAGCATAAAGCAACCCCGATCATGGGGCGCACGTTGGGGCAGATCGCGACGCCGACGACGTTCGGCGCG
CTGACCGGCGGCTGGCTGGTTGCGGTGGACAATGCGGCACGCGCCCTGGAGGCGCTGGAGTTTCCGGTGTCGTATGGCGG
TGCCAGCGGAAATATGACGGCGGTGCACCCGCGTGGCTTCGAGATTCAGGCGAAGCTGGCCGAGGAGTTGGGCCTTTTTG
ATCCGCAGTGGGTGTGGCATTCCGATCGCACGCCGATCACTGCGATCGCGTCGGCGCTGGCAACGGCCGCTGGTGTGGTA
CGCAAAATTGCTGGTGACGTGGTGTTTTACTCACAAACCGAGGTCGGCGAGTTGCGGGAGAAATCCCCCGGCGGCAGCTC
CGCGATGCCCCACAAAGCCAATCCGGCCGCTGCGATTGCGTGCGACGGTTACGCGCGCCGGGCACCTGGCCTTCTTGCAA
CGCTTTTCGACGCCCTCGACTGCCGTTTGCAGCGCGGCACCGGCAGCTGGCACGCGGAGTGGGCAACGCTGCGCGAGTTG
GCTGCTGTCACTCACTCAGCAGTGAGCAGGGCTGCAACCAGCATCGATGGCATCACCGTCAACGTTGATGTGATGGCAAG
TCGCGTCAATGGACCAACCGGGCACGCCGAAGATTTGGCGGAGCGGGCACTAGAAATTTATGGAAAAGGACGCAGTTAA

Upstream 100 bases:

>100_bases
CCAGTTTTGGCTGTGGTCCCAGCTGATCGACGTGACCTCCTGGTGGCTCAAAAGACCGATGATGGATTCCGCTTCGACAT
CACTGTCCAGGCTGAAGACA

Downstream 100 bases:

>100_bases
TGGATCGCTATGAAACCGGAATGAAAAACCGCCGCGAGGTACTGGGAGATGCCCATGTGGATCGCGCCGTGGCGAACACC
ACCGAGGTGACTGAGAAGTT

Product: 3-carboxy-cis,cis-muconate cycloisomerase

Products: NA

Alternate protein names: 3-carboxymuconate lactonizing enzyme; CMLE [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKPHFLDSKLTRSLYSDLAGSGEHLSSLSDETFLKNLLVVEAALAVAAAPEHAAMAKATIDSYQLDVEELSRRAAEGGNP
LIPLVTDLKAINPAGIHIGATSQDIIDSALMLCMKEGVGEVVDKLKKLARDLAELTAEHKATPIMGRTLGQIATPTTFGA
LTGGWLVAVDNAARALEALEFPVSYGGASGNMTAVHPRGFEIQAKLAEELGLFDPQWVWHSDRTPITAIASALATAAGVV
RKIAGDVVFYSQTEVGELREKSPGGSSAMPHKANPAAAIACDGYARRAPGLLATLFDALDCRLQRGTGSWHAEWATLREL
AAVTHSAVSRAATSIDGITVNVDVMASRVNGPTGHAEDLAERALEIYGKGRS

Sequences:

>Translated_372_residues
MKPHFLDSKLTRSLYSDLAGSGEHLSSLSDETFLKNLLVVEAALAVAAAPEHAAMAKATIDSYQLDVEELSRRAAEGGNP
LIPLVTDLKAINPAGIHIGATSQDIIDSALMLCMKEGVGEVVDKLKKLARDLAELTAEHKATPIMGRTLGQIATPTTFGA
LTGGWLVAVDNAARALEALEFPVSYGGASGNMTAVHPRGFEIQAKLAEELGLFDPQWVWHSDRTPITAIASALATAAGVV
RKIAGDVVFYSQTEVGELREKSPGGSSAMPHKANPAAAIACDGYARRAPGLLATLFDALDCRLQRGTGSWHAEWATLREL
AAVTHSAVSRAATSIDGITVNVDVMASRVNGPTGHAEDLAERALEIYGKGRS
>Mature_372_residues
MKPHFLDSKLTRSLYSDLAGSGEHLSSLSDETFLKNLLVVEAALAVAAAPEHAAMAKATIDSYQLDVEELSRRAAEGGNP
LIPLVTDLKAINPAGIHIGATSQDIIDSALMLCMKEGVGEVVDKLKKLARDLAELTAEHKATPIMGRTLGQIATPTTFGA
LTGGWLVAVDNAARALEALEFPVSYGGASGNMTAVHPRGFEIQAKLAEELGLFDPQWVWHSDRTPITAIASALATAAGVV
RKIAGDVVFYSQTEVGELREKSPGGSSAMPHKANPAAAIACDGYARRAPGLLATLFDALDCRLQRGTGSWHAEWATLREL
AAVTHSAVSRAATSIDGITVNVDVMASRVNGPTGHAEDLAERALEIYGKGRS

Specific function: Catalyzes an anti cycloisomerization [H]

COG id: COG0015

COG function: function code F; Adenylosuccinate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II fumarase/aspartase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019468
- InterPro:   IPR003031
- InterPro:   IPR000362
- InterPro:   IPR020557
- InterPro:   IPR008948
- InterPro:   IPR022761
- InterPro:   IPR012789 [H]

Pfam domain/function: PF10397 ADSL_C; PF00206 Lyase_1 [H]

EC number: =5.5.1.2 [H]

Molecular weight: Translated: 39151; Mature: 39151

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00163 FUMARATE_LYASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPHFLDSKLTRSLYSDLAGSGEHLSSLSDETFLKNLLVVEAALAVAAAPEHAAMAKATI
CCCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
DSYQLDVEELSRRAAEGGNPLIPLVTDLKAINPAGIHIGATSQDIIDSALMLCMKEGVGE
HHHCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHH
VVDKLKKLARDLAELTAEHKATPIMGRTLGQIATPTTFGALTGGWLVAVDNAARALEALE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCEEEEECHHHHHHHHHH
FPVSYGGASGNMTAVHPRGFEIQAKLAEELGLFDPQWVWHSDRTPITAIASALATAAGVV
CCHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHH
RKIAGDVVFYSQTEVGELREKSPGGSSAMPHKANPAAAIACDGYARRAPGLLATLFDALD
HHHHCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHCCHHHHHHHHHHH
CRLQRGTGSWHAEWATLRELAAVTHSAVSRAATSIDGITVNVDVMASRVNGPTGHAEDLA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHEEEEECCCCCCCCHHHHH
ERALEIYGKGRS
HHHHHHHCCCCC
>Mature Secondary Structure
MKPHFLDSKLTRSLYSDLAGSGEHLSSLSDETFLKNLLVVEAALAVAAAPEHAAMAKATI
CCCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
DSYQLDVEELSRRAAEGGNPLIPLVTDLKAINPAGIHIGATSQDIIDSALMLCMKEGVGE
HHHCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHH
VVDKLKKLARDLAELTAEHKATPIMGRTLGQIATPTTFGALTGGWLVAVDNAARALEALE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCEEEEECHHHHHHHHHH
FPVSYGGASGNMTAVHPRGFEIQAKLAEELGLFDPQWVWHSDRTPITAIASALATAAGVV
CCHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHH
RKIAGDVVFYSQTEVGELREKSPGGSSAMPHKANPAAAIACDGYARRAPGLLATLFDALD
HHHHCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHCCHHHHHHHHHHH
CRLQRGTGSWHAEWATLRELAAVTHSAVSRAATSIDGITVNVDVMASRVNGPTGHAEDLA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHEEEEECCCCCCCCHHHHH
ERALEIYGKGRS
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1390752 [H]