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The map label for this gene is clpX [H]

Identifier: 62391230

GI number: 62391230

Start: 2501157

End: 2502437

Strand: Reverse

Name: clpX [H]

Synonym: cg2620

Alternate gene names: 62391230

Gene position: 2502437-2501157 (Counterclockwise)

Preceding gene: 62391232

Following gene: 62391229

Centisome position: 76.23

GC content: 52.77

Gene sequence:

>1281_bases
ATGGCACGTATGCAGGAAAGCGCCGATCTGCTCAAATGTTCCTTCTGCGGAAAGAGCCAAAAGCAGGTAAAAAAACTCAT
CGCGGGTGGCGCCGTATATATCTGTGATGAGTGCATTGAGCTGTGCAACGAGATTATTGAAGAAGAACTCGGTCAAGCTC
AACACGACGAGCAGGAGCGCAACGAGCTCCCCAAGCCGTCGGAGATTTCAGCCTTCCTTGATACTTATGTCATCGGGCAG
GACCCAGCAAAACGTATCCTGTCGGTTGCGGTGTACAACCATTACAAGCGTCTCCGCGCATCGGAAACCATCGGTCGTCG
CAGGAATGACGAGCCTGAAACCGAACTGGTTAAGTCCAATATTTTGATGCTCGGCCCCACTGGCTCCGGCAAGACTTTCC
TTGCCCAGACTTTGGCAAAGCTGCTGGATGTTCCTTTTGCTATCGCGGATGCCACCTCACTGACCGAGGCTGGTTATGTG
GGCGAGGATGTGGAAAACATCTTGCTCAAGCTGCTTCAGGCTGCTGATTTTGATGTGGAACGTGCACAGCGCGGCATCAT
TTACATCGATGAAGTGGACAAGATTTCCCGCAAGTCTGAAAACCCATCGATCACTCGCGATGTTTCCGGTGAAGGCGTGC
AGCAGGCACTGCTGAAAATTTTGGAAGGCACTGTCGCCGCAATCCCACCGCAGGGAGGACGCAAGCACCCCAACCAGGAT
TTCATCCAGCTGGATACCACCAACATTTTGTTCATCGTTGCTGGTGCGTTCTCTGGTCTGGAGAAGGTCATCGCGGACCG
CAATGGCAAGAAAGGCTTGGGCTTCGGTGTGGAGGTCTCTTCCAAGAAGGAAGAAGCCAACATTGTGGATATCTTCAAGG
ATGTCCTCCCTGAGGACCTGGTGAAGTTTGGTCTCATCCCAGAATTCATTGGGCGTCTGCCAGTCGTTGCCACCGTATCC
AACCTGGATCAGAAATCTCTGGTCAAGGTTCTCACGGAGCCTCGTAACTCATTGGTGAAGCAGTATCGACGTCTGTTTGA
AATGGATGACGCTGTGTTGACCTTTACTGATGATGCTTTGGAGGAGATCGCTAATCAGGCACTCGAGCGCAAAACTGGCG
CCCGTGGCCTGCGCGCGATCATGGAAGAGATCCTGGTTCCGATCATGTATGACCTCCCAGACCGTAAAGACGTTGGCGAA
GTCATCATCAACGGTGCCGTTGCCCGTGGCGAAGCCGAACCAGAGATGTTGGAAGCTGTCGCAGAAGAAAAGACCGCGTA
G

Upstream 100 bases:

>100_bases
ACAGGTAAAGCGCTAAGATGGAACAACCCATTGCCAATATTGTTGGTTAGAGTTGTACGCAGTAAATCTTTTCAATCGTG
GAAGCGGGTCTCACAGTCTA

Downstream 100 bases:

>100_bases
TTGGCAGGAGTTATCACCGGCTTTGCCATCATCCTGTCGGTTATCGGCGTTGGATTTCTTCTGGCAAAGCTGGGGGTCAT
CAATGATGACAAACAGCGCT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQERNELPKPSEISAFLDTYVIGQ
DPAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSNILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYV
GEDVENILLKLLQAADFDVERAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQD
FIQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEANIVDIFKDVLPEDLVKFGLIPEFIGRLPVVATVS
NLDQKSLVKVLTEPRNSLVKQYRRLFEMDDAVLTFTDDALEEIANQALERKTGARGLRAIMEEILVPIMYDLPDRKDVGE
VIINGAVARGEAEPEMLEAVAEEKTA

Sequences:

>Translated_426_residues
MARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQERNELPKPSEISAFLDTYVIGQ
DPAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSNILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYV
GEDVENILLKLLQAADFDVERAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQD
FIQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEANIVDIFKDVLPEDLVKFGLIPEFIGRLPVVATVS
NLDQKSLVKVLTEPRNSLVKQYRRLFEMDDAVLTFTDDALEEIANQALERKTGARGLRAIMEEILVPIMYDLPDRKDVGE
VIINGAVARGEAEPEMLEAVAEEKTA
>Mature_425_residues
ARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQERNELPKPSEISAFLDTYVIGQD
PAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSNILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYVG
EDVENILLKLLQAADFDVERAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQDF
IQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEANIVDIFKDVLPEDLVKFGLIPEFIGRLPVVATVSN
LDQKSLVKVLTEPRNSLVKQYRRLFEMDDAVLTFTDDALEEIANQALERKTGARGLRAIMEEILVPIMYDLPDRKDVGEV
IINGAVARGEAEPEMLEAVAEEKTA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=514, Percent_Identity=38.9105058365759, Blast_Score=320, Evalue=2e-87,
Organism=Escherichia coli, GI1786642, Length=426, Percent_Identity=60.3286384976526, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI1790366, Length=110, Percent_Identity=44.5454545454545, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982905, Length=317, Percent_Identity=47.0031545741325, Blast_Score=277, Evalue=8e-75,
Organism=Caenorhabditis elegans, GI71982908, Length=317, Percent_Identity=47.0031545741325, Blast_Score=277, Evalue=8e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=396, Percent_Identity=39.1414141414141, Blast_Score=250, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=257, Percent_Identity=40.4669260700389, Blast_Score=176, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=433, Percent_Identity=39.9538106235566, Blast_Score=266, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24648291, Length=332, Percent_Identity=49.0963855421687, Blast_Score=304, Evalue=8e-83,
Organism=Drosophila melanogaster, GI24648289, Length=332, Percent_Identity=49.0963855421687, Blast_Score=303, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46941; Mature: 46810

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQER
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
NELPKPSEISAFLDTYVIGQDPAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSN
HCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
ILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYVGEDVENILLKLLQAADFDVE
EEEECCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHH
RAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQD
HHHCCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCC
FIQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEANIVDIFKDVLPEDL
EEEEECCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
VKFGLIPEFIGRLPVVATVSNLDQKSLVKVLTEPRNSLVKQYRRLFEMDDAVLTFTDDAL
HHHCCHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
EEIANQALERKTGARGLRAIMEEILVPIMYDLPDRKDVGEVIINGAVARGEAEPEMLEAV
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHCCCCCHHHHHHH
AEEKTA
HHHCCC
>Mature Secondary Structure 
ARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQER
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
NELPKPSEISAFLDTYVIGQDPAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSN
HCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
ILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYVGEDVENILLKLLQAADFDVE
EEEECCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHH
RAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQD
HHHCCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCC
FIQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEANIVDIFKDVLPEDL
EEEEECCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
VKFGLIPEFIGRLPVVATVSNLDQKSLVKVLTEPRNSLVKQYRRLFEMDDAVLTFTDDAL
HHHCCHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
EEIANQALERKTGARGLRAIMEEILVPIMYDLPDRKDVGEVIINGAVARGEAEPEMLEAV
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHCCCCCHHHHHHH
AEEKTA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA