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The map label for this gene is obgE [H]

Identifier: 62391200

GI number: 62391200

Start: 2469683

End: 2471188

Strand: Reverse

Name: obgE [H]

Synonym: cg2589

Alternate gene names: 62391200

Gene position: 2471188-2469683 (Counterclockwise)

Preceding gene: 62391202

Following gene: 62391199

Centisome position: 75.28

GC content: 56.24

Gene sequence:

>1506_bases
ATGAACCGATTTATTGACCGCGTTGTGCTACACCTCGCCGCAGGTGACGGCGGCAATGGTTGTGTCTCGGTGCACCGCGA
AAAATTCAAGCCACTTGGTGGACCAGACGGCGGCAACGGCGGCCACGGTGGAGACATCATCTTGGAAGTCACCGCACAGG
TCCACACCCTGCTTGACTTCCACTTCCACCCACACGTGAAGGCCGAGCGCGGCGCTAACGGCGCTGGCGATCATCGCAAC
GGTGCCCGAGGCAAGGACCTTGTCTTGGAAGTTCCACCAGGAACTGTCGTGCTTAATGAAAAGGGCGAGACTCTGGCAGA
CCTGACCAGCGTGGGCATGAAGTTCATCGCTGCTGCTGGCGGTAACGGCGGTTTGGGTAACGCAGCGCTTGCCTCCAAGG
CTCGTAAGGCCCCAGGCTTCGCCCTGATCGGTGAGCCAGGCGAGGCCCACGACTTGATTCTTGAACTCAAATCCATGGCA
GATGTGGGATTGGTGGGCTTCCCATCAGCCGGCAAATCATCACTGATTTCTGTGATGTCTGCAGCAAAGCCAAAGATCGG
TGATTACCCATTCACCACCCTGCAGCCAAACCTCGGCGTAGTTAACGTTGGTCATGAGACTTTCACCATGGCAGACGTGC
CTGGTTTGATCCCTGGTGCTTCTGAGGGCAAGGGCTTGGGTCTGGATTTCTTGCGCCACATTGAGCGCACCTCCGTGCTG
GTTCACGTTGTCGATACCGCAACGATGGATCCAGGCCGCGATCCGATCTCTGATATTGAGGCTTTGGAAGCAGAACTTGC
CGCCTACCAGTCGGCTTTGGATGAAGACACCGGACTTGGTGACTTGAGCCAGCGCCCTCGCCTTGTTGTGTTGAACAAGG
CTGATGTCCCTGAGGCTGAAGAGCTTGCTGAGTTCCTCAAAGAAGATATTGAGAAGCAATTCGGATGGCCCGTGTTCATT
ATCTCCGCAGTGGCACGCAAGGGCTTGGATCCTTTGAAGTACAAGCTGCTGGAAATCGTCCAGGATGCCCGAAAGAAGCG
TCCAAAGGAGAAGGCTGAGTCTGTCATCATTAAGCCTAAGGCTGTTGATCACCGCACTAAGGGGCAGTTCCAGATCAAGC
CTGACCCAGAGGTTCAGGGCGGATTCATCATCACCGGCGAAAAGCCAGAGCGCTGGATTTTGCAGACCGACTTTGAAAAC
GACGAAGCAGTTGGCTACCTGGCTGACCGTCTGGCCAAGTTGGGCATTGAGGACGGGCTTCGTAAGGCAGGAGCACATGT
GGGTGCAAACGTCACCATCGGAGGCATTTCCTTCGAGTGGGAGCCAATGACCACCGCTGGCGACGATCCAGTCCTTACCG
GACGTGGCACCGATGTGCGCCTTGAACAGACCTCTCGTATCTCTGCTGCAGAGCGTAAACGCGCATCTCAGGTACGTCGT
GGCCTCATCGATGAGTTGGATTATGGCGAGGACCAAGAGGCTTCCCGCGAACGCTGGGAAGGATAA

Upstream 100 bases:

>100_bases
ACTGGTAGGATCGAAGAACCTTGGCGCCCACACATCCCCCTTTATTTTTCTACTTATACGTCGGCGCCCGTTTTATCCCG
ATCAGGAGTGACACCGTTTT

Downstream 100 bases:

>100_bases
AACCGAGCACTTTTCAGGTCTACGTGTATACGATGGTAACGCTATGAATGATACGCAGAACACACCTGAAAGCGTTCGAT
TACGGGATAATCTCCCAACG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MNRFIDRVVLHLAAGDGGNGCVSVHREKFKPLGGPDGGNGGHGGDIILEVTAQVHTLLDFHFHPHVKAERGANGAGDHRN
GARGKDLVLEVPPGTVVLNEKGETLADLTSVGMKFIAAAGGNGGLGNAALASKARKAPGFALIGEPGEAHDLILELKSMA
DVGLVGFPSAGKSSLISVMSAAKPKIGDYPFTTLQPNLGVVNVGHETFTMADVPGLIPGASEGKGLGLDFLRHIERTSVL
VHVVDTATMDPGRDPISDIEALEAELAAYQSALDEDTGLGDLSQRPRLVVLNKADVPEAEELAEFLKEDIEKQFGWPVFI
ISAVARKGLDPLKYKLLEIVQDARKKRPKEKAESVIIKPKAVDHRTKGQFQIKPDPEVQGGFIITGEKPERWILQTDFEN
DEAVGYLADRLAKLGIEDGLRKAGAHVGANVTIGGISFEWEPMTTAGDDPVLTGRGTDVRLEQTSRISAAERKRASQVRR
GLIDELDYGEDQEASRERWEG

Sequences:

>Translated_501_residues
MNRFIDRVVLHLAAGDGGNGCVSVHREKFKPLGGPDGGNGGHGGDIILEVTAQVHTLLDFHFHPHVKAERGANGAGDHRN
GARGKDLVLEVPPGTVVLNEKGETLADLTSVGMKFIAAAGGNGGLGNAALASKARKAPGFALIGEPGEAHDLILELKSMA
DVGLVGFPSAGKSSLISVMSAAKPKIGDYPFTTLQPNLGVVNVGHETFTMADVPGLIPGASEGKGLGLDFLRHIERTSVL
VHVVDTATMDPGRDPISDIEALEAELAAYQSALDEDTGLGDLSQRPRLVVLNKADVPEAEELAEFLKEDIEKQFGWPVFI
ISAVARKGLDPLKYKLLEIVQDARKKRPKEKAESVIIKPKAVDHRTKGQFQIKPDPEVQGGFIITGEKPERWILQTDFEN
DEAVGYLADRLAKLGIEDGLRKAGAHVGANVTIGGISFEWEPMTTAGDDPVLTGRGTDVRLEQTSRISAAERKRASQVRR
GLIDELDYGEDQEASRERWEG
>Mature_501_residues
MNRFIDRVVLHLAAGDGGNGCVSVHREKFKPLGGPDGGNGGHGGDIILEVTAQVHTLLDFHFHPHVKAERGANGAGDHRN
GARGKDLVLEVPPGTVVLNEKGETLADLTSVGMKFIAAAGGNGGLGNAALASKARKAPGFALIGEPGEAHDLILELKSMA
DVGLVGFPSAGKSSLISVMSAAKPKIGDYPFTTLQPNLGVVNVGHETFTMADVPGLIPGASEGKGLGLDFLRHIERTSVL
VHVVDTATMDPGRDPISDIEALEAELAAYQSALDEDTGLGDLSQRPRLVVLNKADVPEAEELAEFLKEDIEKQFGWPVFI
ISAVARKGLDPLKYKLLEIVQDARKKRPKEKAESVIIKPKAVDHRTKGQFQIKPDPEVQGGFIITGEKPERWILQTDFEN
DEAVGYLADRLAKLGIEDGLRKAGAHVGANVTIGGISFEWEPMTTAGDDPVLTGRGTDVRLEQTSRISAAERKRASQVRR
GLIDELDYGEDQEASRERWEG

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=341, Percent_Identity=39.2961876832845, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI111955139, Length=239, Percent_Identity=38.0753138075314, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI111955063, Length=141, Percent_Identity=41.8439716312057, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI58761500, Length=128, Percent_Identity=31.25, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789574, Length=364, Percent_Identity=43.6813186813187, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1787454, Length=129, Percent_Identity=34.1085271317829, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=339, Percent_Identity=41.0029498525074, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=318, Percent_Identity=28.9308176100629, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17509631, Length=140, Percent_Identity=30.7142857142857, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=206, Percent_Identity=37.8640776699029, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6321649, Length=141, Percent_Identity=34.0425531914894, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319281, Length=108, Percent_Identity=35.1851851851852, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI20129375, Length=321, Percent_Identity=39.2523364485981, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24585318, Length=243, Percent_Identity=38.6831275720165, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24640873, Length=173, Percent_Identity=28.9017341040462, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640877, Length=173, Percent_Identity=28.9017341040462, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640875, Length=173, Percent_Identity=28.9017341040462, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356473, Length=124, Percent_Identity=37.9032258064516, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 53621; Mature: 53621

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFIDRVVLHLAAGDGGNGCVSVHREKFKPLGGPDGGNGGHGGDIILEVTAQVHTLLDF
CCHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHH
HFHPHVKAERGANGAGDHRNGARGKDLVLEVPPGTVVLNEKGETLADLTSVGMKFIAAAG
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHEEECC
GNGGLGNAALASKARKAPGFALIGEPGEAHDLILELKSMADVGLVGFPSAGKSSLISVMS
CCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
AAKPKIGDYPFTTLQPNLGVVNVGHETFTMADVPGLIPGASEGKGLGLDFLRHIERTSVL
HCCCCCCCCCCCEECCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHEE
VHVVDTATMDPGRDPISDIEALEAELAAYQSALDEDTGLGDLSQRPRLVVLNKADVPEAE
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHH
ELAEFLKEDIEKQFGWPVFIISAVARKGLDPLKYKLLEIVQDARKKRPKEKAESVIIKPK
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCEEECCC
AVDHRTKGQFQIKPDPEVQGGFIITGEKPERWILQTDFENDEAVGYLADRLAKLGIEDGL
CCCCCCCCEEEECCCCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHH
RKAGAHVGANVTIGGISFEWEPMTTAGDDPVLTGRGTDVRLEQTSRISAAERKRASQVRR
HHHCCCCCCEEEEECEEEEECCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHH
GLIDELDYGEDQEASRERWEG
HHHHHCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MNRFIDRVVLHLAAGDGGNGCVSVHREKFKPLGGPDGGNGGHGGDIILEVTAQVHTLLDF
CCHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHH
HFHPHVKAERGANGAGDHRNGARGKDLVLEVPPGTVVLNEKGETLADLTSVGMKFIAAAG
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHEEECC
GNGGLGNAALASKARKAPGFALIGEPGEAHDLILELKSMADVGLVGFPSAGKSSLISVMS
CCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
AAKPKIGDYPFTTLQPNLGVVNVGHETFTMADVPGLIPGASEGKGLGLDFLRHIERTSVL
HCCCCCCCCCCCEECCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHEE
VHVVDTATMDPGRDPISDIEALEAELAAYQSALDEDTGLGDLSQRPRLVVLNKADVPEAE
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHH
ELAEFLKEDIEKQFGWPVFIISAVARKGLDPLKYKLLEIVQDARKKRPKEKAESVIIKPK
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCEEECCC
AVDHRTKGQFQIKPDPEVQGGFIITGEKPERWILQTDFENDEAVGYLADRLAKLGIEDGL
CCCCCCCCEEEECCCCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHH
RKAGAHVGANVTIGGISFEWEPMTTAGDDPVLTGRGTDVRLEQTSRISAAERKRASQVRR
HHHCCCCCCEEEEECEEEEECCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHH
GLIDELDYGEDQEASRERWEG
HHHHHCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA