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The map label for this gene is ectP [H]

Identifier: 62391153

GI number: 62391153

Start: 2420000

End: 2421847

Strand: Reverse

Name: ectP [H]

Synonym: cg2539

Alternate gene names: 62391153

Gene position: 2421847-2420000 (Counterclockwise)

Preceding gene: 62391154

Following gene: 62391149

Centisome position: 73.78

GC content: 48.38

Gene sequence:

>1848_bases
ATGAGCTCAAATATAGCTATCACGACCGAGCCTGAAGGGAAAAATAAAAAGGGTCTCAAATCAGACCCGTTCATTTTTTC
CATTTCTGTCGGTTTTATCGTGGTGTTTGTCATCGCCACAATTGCGCTAGGCGAGAAAGCTCGAACAACCTTTTCCGCGA
TTGCCGGCTGGCTCTTAGAAAATTTAGGGTGGATGTATATCGGGGGTGTCTCCTTGGTTTTCATTTTCCTCATGGGTATC
TTTGCGTCCCGGTATGGCCGGGTAAAACTTGGTGATGACGATGATGACCCCGAGCACACCCTAATCGTGTGGTTCTGTAT
GCTTTTTGCTGGCGGTGTCGGTGCAGTCTTAATGTTTTGGGGTGTTGCCGAACCGATTAACCACGCGTTCAACGTGCCAA
TGGCTAATGAAGAATCCATGAGTGAAGCCGCAATTGTGCAGGCTTTTGCTTATACTTTCTATCACTTCGGTATTCACATG
TGGGTAATCATGGCACTCCCAGGATTATCATTGGGATACTTTATTTACAAACGTAAGCTACCTCCCCGTCTATCCTCTGT
GTTTTCTCCGATCTTGGGTAAGCACATTTATTCCACACCCGGCAAGCTCATCGATGTACTGGCCATCGTAGGCACCACGT
TTGGTATTGCTGTGTCAGTAGGTCTTGGTGTGCTGCAAATCAATGCAGGTATGAACAAACTATGGAGCACCCCGCAAGTA
TCGTGGGTTCAGCTTTTGATCATCTTGATCATCACCGCGGTTGCATGTATTTCCGTTGCTTCCGGTTTGGATAAGGGCAT
TAAGTTACTGTCCAACATTAATATTGCAATGGCCGTTGCGTTGATGTTCTTCATCTTGTTCACTGGTCCAACCCTCACAT
TGCTGCGCTTTCTCGTAGAATCCTTCGGAATCTATGCATCCTGGATGCCTAATCTGATGTTTTGGACTGACTCTTTCCAA
GATAACCCAGGCTGGCAGGGCAAATGGACGGTGTTCTATTGGGCATGGACTATTTGTTGGTCGCCATATGTCGGCATGTT
CGTGGCGCGTATTTCGCGTGGACGTACCGTCCGTGAATTTATCGGTGGGGTTCTAGCTCTGCCAGCGATCTTTGGCGTAG
TTTGGTTCTCTATCTTTGGTCGTGCAGGCATCGAAGTGGAACTGAGTAACCCAGGTTTCTTGACCCAGCCAACTGTTGTT
GAAGGTGACGTGCCAGCAGCGCTTTTTAATGTGCTGCAAGAGTATCCGCTGACTGGAATTGTCTCCGCGTTTGCACTTGT
AATTATTGTGATTTTCTTTATCACCTCCATCGATTCCGCAGCGCTAGTTAACGATATGTTCGCTACCGGTGCAGAAAATC
AAACACCGACTAGTTACCGCGTGATGTGGGCCTGCACCATTGGGGCGGTCGCAGGTTCCTTGCTGATCATTTCCCCATCC
TCTGGTATTGCCACGCTGCAAGAAGTGGTTATCATCGTGGCTTTCCCATTCTTCCTCGTGCAATTTGTCATGATGTTTTC
TTTGCTTAAAGGCATGAGTGAAGATGCTGCTGCGGTTCGTCGTGTGCAGACTCGTCAGTGGGAAAAGACTGATACACCAG
AAAAACTTGAAGAGCATTCGTCCCAACCAGCCCCGGGCTATGATGACGAGGGCAACCCCTTGCCAATGCCTGCCCTCGAA
CATGATGAGGACGGTAACATTGTTATCCCAGGCAACGTAGTCATTGAAGGTGATCTTGGGGTAGTTGGTGATGTGGTCGA
CGATCCTGAGGAAGCCCAAGAGATGGGGTCTCGTTTTAAGATCGTCGAGCAAACTCGGCCCCAGTCCAGGGACGAATACG
ATATTTAA

Upstream 100 bases:

>100_bases
TTTAGACAAGTTCTGGTTAAAATTCTTCATGAAGGTGAGAATCTGGGAATTTCTCGGTACTCTTTCAGATTCGTAGTTAT
CCACTGATTGGAAGAATGAG

Downstream 100 bases:

>100_bases
ACGATTGCTTTTCGACGCACCTCCCACCCTGTTTAAGTATCCCGCGTGGGGTGGGACGGCAGAGAATCGTTGGTAAAAAC
CCAGCCTTGTGGAAAACCTG

Product: ectoine/proline/glycine betaine carrier EctP

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MSSNIAITTEPEGKNKKGLKSDPFIFSISVGFIVVFVIATIALGEKARTTFSAIAGWLLENLGWMYIGGVSLVFIFLMGI
FASRYGRVKLGDDDDDPEHTLIVWFCMLFAGGVGAVLMFWGVAEPINHAFNVPMANEESMSEAAIVQAFAYTFYHFGIHM
WVIMALPGLSLGYFIYKRKLPPRLSSVFSPILGKHIYSTPGKLIDVLAIVGTTFGIAVSVGLGVLQINAGMNKLWSTPQV
SWVQLLIILIITAVACISVASGLDKGIKLLSNINIAMAVALMFFILFTGPTLTLLRFLVESFGIYASWMPNLMFWTDSFQ
DNPGWQGKWTVFYWAWTICWSPYVGMFVARISRGRTVREFIGGVLALPAIFGVVWFSIFGRAGIEVELSNPGFLTQPTVV
EGDVPAALFNVLQEYPLTGIVSAFALVIIVIFFITSIDSAALVNDMFATGAENQTPTSYRVMWACTIGAVAGSLLIISPS
SGIATLQEVVIIVAFPFFLVQFVMMFSLLKGMSEDAAAVRRVQTRQWEKTDTPEKLEEHSSQPAPGYDDEGNPLPMPALE
HDEDGNIVIPGNVVIEGDLGVVGDVVDDPEEAQEMGSRFKIVEQTRPQSRDEYDI

Sequences:

>Translated_615_residues
MSSNIAITTEPEGKNKKGLKSDPFIFSISVGFIVVFVIATIALGEKARTTFSAIAGWLLENLGWMYIGGVSLVFIFLMGI
FASRYGRVKLGDDDDDPEHTLIVWFCMLFAGGVGAVLMFWGVAEPINHAFNVPMANEESMSEAAIVQAFAYTFYHFGIHM
WVIMALPGLSLGYFIYKRKLPPRLSSVFSPILGKHIYSTPGKLIDVLAIVGTTFGIAVSVGLGVLQINAGMNKLWSTPQV
SWVQLLIILIITAVACISVASGLDKGIKLLSNINIAMAVALMFFILFTGPTLTLLRFLVESFGIYASWMPNLMFWTDSFQ
DNPGWQGKWTVFYWAWTICWSPYVGMFVARISRGRTVREFIGGVLALPAIFGVVWFSIFGRAGIEVELSNPGFLTQPTVV
EGDVPAALFNVLQEYPLTGIVSAFALVIIVIFFITSIDSAALVNDMFATGAENQTPTSYRVMWACTIGAVAGSLLIISPS
SGIATLQEVVIIVAFPFFLVQFVMMFSLLKGMSEDAAAVRRVQTRQWEKTDTPEKLEEHSSQPAPGYDDEGNPLPMPALE
HDEDGNIVIPGNVVIEGDLGVVGDVVDDPEEAQEMGSRFKIVEQTRPQSRDEYDI
>Mature_614_residues
SSNIAITTEPEGKNKKGLKSDPFIFSISVGFIVVFVIATIALGEKARTTFSAIAGWLLENLGWMYIGGVSLVFIFLMGIF
ASRYGRVKLGDDDDDPEHTLIVWFCMLFAGGVGAVLMFWGVAEPINHAFNVPMANEESMSEAAIVQAFAYTFYHFGIHMW
VIMALPGLSLGYFIYKRKLPPRLSSVFSPILGKHIYSTPGKLIDVLAIVGTTFGIAVSVGLGVLQINAGMNKLWSTPQVS
WVQLLIILIITAVACISVASGLDKGIKLLSNINIAMAVALMFFILFTGPTLTLLRFLVESFGIYASWMPNLMFWTDSFQD
NPGWQGKWTVFYWAWTICWSPYVGMFVARISRGRTVREFIGGVLALPAIFGVVWFSIFGRAGIEVELSNPGFLTQPTVVE
GDVPAALFNVLQEYPLTGIVSAFALVIIVIFFITSIDSAALVNDMFATGAENQTPTSYRVMWACTIGAVAGSLLIISPSS
GIATLQEVVIIVAFPFFLVQFVMMFSLLKGMSEDAAAVRRVQTRQWEKTDTPEKLEEHSSQPAPGYDDEGNPLPMPALEH
DEDGNIVIPGNVVIEGDLGVVGDVVDDPEEAQEMGSRFKIVEQTRPQSRDEYDI

Specific function: High-affinity uptake of glycine betaine [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=611, Percent_Identity=32.0785597381342, Blast_Score=323, Evalue=2e-89,
Organism=Escherichia coli, GI1788102, Length=471, Percent_Identity=26.7515923566879, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1786224, Length=510, Percent_Identity=24.5098039215686, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 67403; Mature: 67272

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNIAITTEPEGKNKKGLKSDPFIFSISVGFIVVFVIATIALGEKARTTFSAIAGWLLE
CCCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NLGWMYIGGVSLVFIFLMGIFASRYGRVKLGDDDDDPEHTLIVWFCMLFAGGVGAVLMFW
CCCEEEEHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
GVAEPINHAFNVPMANEESMSEAAIVQAFAYTFYHFGIHMWVIMALPGLSLGYFIYKRKL
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
PPRLSSVFSPILGKHIYSTPGKLIDVLAIVGTTFGIAVSVGLGVLQINAGMNKLWSTPQV
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCCH
SWVQLLIILIITAVACISVASGLDKGIKLLSNINIAMAVALMFFILFTGPTLTLLRFLVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
SFGIYASWMPNLMFWTDSFQDNPGWQGKWTVFYWAWTICWSPYVGMFVARISRGRTVREF
HHCHHHHHCCCCEEEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHH
IGGVLALPAIFGVVWFSIFGRAGIEVELSNPGFLTQPTVVEGDVPAALFNVLQEYPLTGI
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEECCCCHHHHHHHHHHCCHHHH
VSAFALVIIVIFFITSIDSAALVNDMFATGAENQTPTSYRVMWACTIGAVAGSLLIISPS
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHCCEEEECCC
SGIATLQEVVIIVAFPFFLVQFVMMFSLLKGMSEDAAAVRRVQTRQWEKTDTPEKLEEHS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCC
SQPAPGYDDEGNPLPMPALEHDEDGNIVIPGNVVIEGDLGVVGDVVDDPEEAQEMGSRFK
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHEE
IVEQTRPQSRDEYDI
HHHHCCCCCCCCCCC
>Mature Secondary Structure 
SSNIAITTEPEGKNKKGLKSDPFIFSISVGFIVVFVIATIALGEKARTTFSAIAGWLLE
CCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH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HHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8752321; 9387221; 9384377 [H]