Click here to switch to the map view.

The map label for this gene is mraW [H]

Identifier: 62391005

GI number: 62391005

Start: 2265786

End: 2266799

Strand: Reverse

Name: mraW [H]

Synonym: cg2377

Alternate gene names: 62391005

Gene position: 2266799-2265786 (Counterclockwise)

Preceding gene: 62391006

Following gene: 62391004

Centisome position: 69.05

GC content: 55.13

Gene sequence:

>1014_bases
ATGGAAGATTTTTCCTTGGATGGCAACCACGGACACGTTCCCGTAATGCGTGATCGTATGGCGGCTTTGATCGCCGAACA
CGTGGAAGCATTGGGAGAAAACGCTGTCATTGTTGACGCAACCCTTGGCGCAGGCGGGCATGCGGAGTTCTTCCTGAACA
CGTTCCCCAAAGCGCGCCTGATTGGCCTTGATCGTGACCAAAATGCGTTGCGGGATGCTCGCGCGCGACTTGCTCCTTTC
GGGGAGCGGTTCATTGGCGTCCAGACGCGTTTCGACGGACTCCGCGAGGTGTTGGAATCTGTCGAGGGCGACATCATTGA
TTTAGCTCGCGAGCACGGTATCGCTGGCGCTCTGTTTGATCTGGGTGTCTCCTCGATGCAGCTTGATCAGGTGGAGCGTG
GCTTTGCCTACCGCACGGACGCGCCTCTGGACATGCGCATGGATGCAACTCAGGGTATTACGGCTGCAGATATCCTCAAC
ACTTATTCGCATGGTGACATCGCTCGAATCTTGAAGACTTACGGCGATGAACGCTTCGCCGGCAAGATTGCTTCTGCGGT
GCTGAAAGAACGTGAAAAAGAGCCGTTCACTACCTCTGCTCGTTTGGTGGAGCTTCTGTACGACGCCATCCCTGCAGCGA
CCCGCCGAACCGGTGGACACCCCGCGAAACGTACTTTCCAGGCGTTGCGCGTTGAGGTGAACAACGAGCTTGATTCCCTG
AAGAATGTGCTTCCTCAAATCACTGACGCCCTCAATGTTGGGGGACGTGCAGTGTTTATGAGCTACCAGTCTCATGAGGA
CAAGCTGGTGAAGAAGTTCTTCACGGATCTGACCACCTCTAAGACCCCTCCGGGCTTGCCTGTTGATCTTCCTGGAACTG
CACCACAGTTTAAGCAGGTTACTCGCGGTGCTGAAACGGCTTCGGAAGCTGAAATTGAAGAAAACCCACGTGCCGCACCT
GTGAAGGTGCGCGCAATCGAAAGAATCGGCAACAACTCAGGAGACCTCTCATGA

Upstream 100 bases:

>100_bases
TGATATGTGGCTATGACATTGTCGCGCAGTTTTTTTATCCACAAACATAAGTACAAGACATTGGACATCTAGGCCGGCAG
GAAAAGGGGGGAACACGCAC

Downstream 100 bases:

>100_bases
CCATGACAAATGGCTCCCGCACAGAGTCGGGAAAGATTCGCGATCGACGTGTCGCTGACGCTGATCCACGGTATGGCCGT
CGCGTCTCGGTGAGTAGGGA

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MEDFSLDGNHGHVPVMRDRMAALIAEHVEALGENAVIVDATLGAGGHAEFFLNTFPKARLIGLDRDQNALRDARARLAPF
GERFIGVQTRFDGLREVLESVEGDIIDLAREHGIAGALFDLGVSSMQLDQVERGFAYRTDAPLDMRMDATQGITAADILN
TYSHGDIARILKTYGDERFAGKIASAVLKEREKEPFTTSARLVELLYDAIPAATRRTGGHPAKRTFQALRVEVNNELDSL
KNVLPQITDALNVGGRAVFMSYQSHEDKLVKKFFTDLTTSKTPPGLPVDLPGTAPQFKQVTRGAETASEAEIEENPRAAP
VKVRAIERIGNNSGDLS

Sequences:

>Translated_337_residues
MEDFSLDGNHGHVPVMRDRMAALIAEHVEALGENAVIVDATLGAGGHAEFFLNTFPKARLIGLDRDQNALRDARARLAPF
GERFIGVQTRFDGLREVLESVEGDIIDLAREHGIAGALFDLGVSSMQLDQVERGFAYRTDAPLDMRMDATQGITAADILN
TYSHGDIARILKTYGDERFAGKIASAVLKEREKEPFTTSARLVELLYDAIPAATRRTGGHPAKRTFQALRVEVNNELDSL
KNVLPQITDALNVGGRAVFMSYQSHEDKLVKKFFTDLTTSKTPPGLPVDLPGTAPQFKQVTRGAETASEAEIEENPRAAP
VKVRAIERIGNNSGDLS
>Mature_337_residues
MEDFSLDGNHGHVPVMRDRMAALIAEHVEALGENAVIVDATLGAGGHAEFFLNTFPKARLIGLDRDQNALRDARARLAPF
GERFIGVQTRFDGLREVLESVEGDIIDLAREHGIAGALFDLGVSSMQLDQVERGFAYRTDAPLDMRMDATQGITAADILN
TYSHGDIARILKTYGDERFAGKIASAVLKEREKEPFTTSARLVELLYDAIPAATRRTGGHPAKRTFQALRVEVNNELDSL
KNVLPQITDALNVGGRAVFMSYQSHEDKLVKKFFTDLTTSKTPPGLPVDLPGTAPQFKQVTRGAETASEAEIEENPRAAP
VKVRAIERIGNNSGDLS

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=282, Percent_Identity=35.8156028368794, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI165377202, Length=200, Percent_Identity=35, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1786270, Length=329, Percent_Identity=37.6899696048632, Blast_Score=189, Evalue=3e-49,
Organism=Drosophila melanogaster, GI62472493, Length=341, Percent_Identity=33.1378299120235, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28571637, Length=341, Percent_Identity=33.1378299120235, Blast_Score=155, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 36809; Mature: 36809

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDFSLDGNHGHVPVMRDRMAALIAEHVEALGENAVIVDATLGAGGHAEFFLNTFPKARL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCEE
IGLDRDQNALRDARARLAPFGERFIGVQTRFDGLREVLESVEGDIIDLAREHGIAGALFD
EECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
LGVSSMQLDQVERGFAYRTDAPLDMRMDATQGITAADILNTYSHGDIARILKTYGDERFA
HCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHH
GKIASAVLKEREKEPFTTSARLVELLYDAIPAATRRTGGHPAKRTFQALRVEVNNELDSL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
KNVLPQITDALNVGGRAVFMSYQSHEDKLVKKFFTDLTTSKTPPGLPVDLPGTAPQFKQV
HHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHH
TRGAETASEAEIEENPRAAPVKVRAIERIGNNSGDLS
HHCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEDFSLDGNHGHVPVMRDRMAALIAEHVEALGENAVIVDATLGAGGHAEFFLNTFPKARL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCEE
IGLDRDQNALRDARARLAPFGERFIGVQTRFDGLREVLESVEGDIIDLAREHGIAGALFD
EECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
LGVSSMQLDQVERGFAYRTDAPLDMRMDATQGITAADILNTYSHGDIARILKTYGDERFA
HCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHH
GKIASAVLKEREKEPFTTSARLVELLYDAIPAATRRTGGHPAKRTFQALRVEVNNELDSL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
KNVLPQITDALNVGGRAVFMSYQSHEDKLVKKFFTDLTTSKTPPGLPVDLPGTAPQFKQV
HHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHH
TRGAETASEAEIEENPRAAPVKVRAIERIGNNSGDLS
HHCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA