Click here to switch to the map view.

The map label for this gene is ftsZ

Identifier: 62390994

GI number: 62390994

Start: 2250559

End: 2251887

Strand: Reverse

Name: ftsZ

Synonym: cg2366

Alternate gene names: 62390994

Gene position: 2251887-2250559 (Counterclockwise)

Preceding gene: 62390995

Following gene: 62390993

Centisome position: 68.6

GC content: 59.52

Gene sequence:

>1329_bases
ATGACCTCACCGAACAACTACCTCGCCAAGATTAAGGTCGTCGGCGTGGGCGGCGGCGGAGTCAACGCCGTCAACCGCAT
GATTGAAGAAGGCCTCAAAGGCGTGGAGTTCATCGCGGTGAACACCGACTCGCAGGCTCTCATGTTCTCTGATGCCGACG
TAAAGCTCGATATCGGACGTGAAGCTACCCGTGGTCTTGGTGCCGGCGCGAACCCAGAAGTTGGACGTGCCTCGGCAGAG
GATCACAAGAACGAAATCGAAGAAACCATCAAGGGCGCCGACATGGTCTTCGTTACCGCCGGCGAAGGTGGTGGCACCGG
AACTGGTGCTGCACCAGTCGTGGCAGGGATCGCCAAGAAGATGGGCGCACTGACCATTGGTGTTGTGACCAAGCCTTTCG
AGTTCGAAGGCCGTCGCCGTACTCGCCAGGCAGAAGAAGGCATCGCAGCACTGAAGGAGGTCTGCGACACCCTCATCGTT
ATTCCAAACGACCGCCTGCTTGAGCTGGGCGATGCGAACCTGTCCATCATGGAAGCGTTCCGCGCAGCCGATGAAGTTCT
CCACAATGGTGTTCAGGGTATTACCAACCTGATCACCATCCCTGGTGTGATCAACGTGGACTTCGCGGACGTTCGCTCCG
TCATGTCCGAAGCTGGTTCCGCACTCATGGGTGTGGGCTCTGCACGTGGGGACAACCGCGTTGTCTCTGCAACCGAGCAG
GCCATCAACTCTCCACTTCTCGAAGCAACAATGGACGGCGCAACTGGCGTCCTGCTGTCCTTTGCTGGTGGATCCGACCT
GGGCCTCATGGAAGTCAACGCAGCTGCATCCATGGTCCGTGAGCGTTCCGATGAAGATGTCAACCTCATCTTCGGTACCA
TCATCGACGACAACCTGGGCGACGAAGTCCGCGTAACCGTCATCGCGACCGGTTTTGACGCAGCTCGCGCAAGCGCCGCT
GAGAACCGCCGCGCAGGCATCTCAGCTGCACCTGCAGCTGAGCCAGTCCAGCAGCAGGTCCCAACCACCAACGCAACCCT
TCCACCAGAGAAGGAAAGCATCTTCGGTGGTGCACGTGAGGAGAACGATCCTTACCTGTCCCGCTCTGCTGGTGCACGTC
ATCGCATTGAGGAGACCCGCTCCGGCGGTGGACTCTTCACCACCGGCAATGATCGCGATTACCGTCGTGATGAGCGCCGC
GAAGATCACCGTGACGAGCGCCGCGATGAGCGCCGCGATGACCGTTCCTACGACCGCCGTGATGATCGTCGTGACGATCG
CCGCGATGACCGCGGAGACGACCTGGATGTACCCAGCTTCCTCCAGTAA

Upstream 100 bases:

>100_bases
ACTTTTAGATAAGCTCTCACAGTGCTGACTGCTTATCTGAGATGAAAATAAAAGCAAAATTTTTTTTAGTATCAACTCTT
CGAAAGGCGAGACATCGACA

Downstream 100 bases:

>100_bases
TTAAGAAGGAGAATAGACTTATCCACTATGGATAGTCTTGACCCCCGCAACCGCCCCGTCCGCAAGGTCTTCACGACCCG
TGCCGGCGGGGTTTCGCAGT

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTSPNNYLAKIKVVGVGGGGVNAVNRMIEEGLKGVEFIAVNTDSQALMFSDADVKLDIGREATRGLGAGANPEVGRASAE
DHKNEIEETIKGADMVFVTAGEGGGTGTGAAPVVAGIAKKMGALTIGVVTKPFEFEGRRRTRQAEEGIAALKEVCDTLIV
IPNDRLLELGDANLSIMEAFRAADEVLHNGVQGITNLITIPGVINVDFADVRSVMSEAGSALMGVGSARGDNRVVSATEQ
AINSPLLEATMDGATGVLLSFAGGSDLGLMEVNAAASMVRERSDEDVNLIFGTIIDDNLGDEVRVTVIATGFDAARASAA
ENRRAGISAAPAAEPVQQQVPTTNATLPPEKESIFGGAREENDPYLSRSAGARHRIEETRSGGGLFTTGNDRDYRRDERR
EDHRDERRDERRDDRSYDRRDDRRDDRRDDRGDDLDVPSFLQ

Sequences:

>Translated_442_residues
MTSPNNYLAKIKVVGVGGGGVNAVNRMIEEGLKGVEFIAVNTDSQALMFSDADVKLDIGREATRGLGAGANPEVGRASAE
DHKNEIEETIKGADMVFVTAGEGGGTGTGAAPVVAGIAKKMGALTIGVVTKPFEFEGRRRTRQAEEGIAALKEVCDTLIV
IPNDRLLELGDANLSIMEAFRAADEVLHNGVQGITNLITIPGVINVDFADVRSVMSEAGSALMGVGSARGDNRVVSATEQ
AINSPLLEATMDGATGVLLSFAGGSDLGLMEVNAAASMVRERSDEDVNLIFGTIIDDNLGDEVRVTVIATGFDAARASAA
ENRRAGISAAPAAEPVQQQVPTTNATLPPEKESIFGGAREENDPYLSRSAGARHRIEETRSGGGLFTTGNDRDYRRDERR
EDHRDERRDERRDDRSYDRRDDRRDDRRDDRGDDLDVPSFLQ
>Mature_441_residues
TSPNNYLAKIKVVGVGGGGVNAVNRMIEEGLKGVEFIAVNTDSQALMFSDADVKLDIGREATRGLGAGANPEVGRASAED
HKNEIEETIKGADMVFVTAGEGGGTGTGAAPVVAGIAKKMGALTIGVVTKPFEFEGRRRTRQAEEGIAALKEVCDTLIVI
PNDRLLELGDANLSIMEAFRAADEVLHNGVQGITNLITIPGVINVDFADVRSVMSEAGSALMGVGSARGDNRVVSATEQA
INSPLLEATMDGATGVLLSFAGGSDLGLMEVNAAASMVRERSDEDVNLIFGTIIDDNLGDEVRVTVIATGFDAARASAAE
NRRAGISAAPAAEPVQQQVPTTNATLPPEKESIFGGAREENDPYLSRSAGARHRIEETRSGGGLFTTGNDRDYRRDERRE
DHRDERRDERRDDRSYDRRDDRRDDRRDDRGDDLDVPSFLQ

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family

Homologues:

Organism=Escherichia coli, GI1786284, Length=292, Percent_Identity=51.7123287671233, Blast_Score=261, Evalue=7e-71,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): FTSZ_CORGL (P94337)

Other databases:

- EMBL:   AB003132
- EMBL:   Y08964
- EMBL:   BA000036
- EMBL:   BX927154
- PIR:   JC5548
- RefSeq:   NP_601357.1
- RefSeq:   YP_226396.1
- ProteinModelPortal:   P94337
- SMR:   P94337
- World-2DPAGE:   0001:P94337
- PRIDE:   P94337
- GeneID:   1020107
- GeneID:   3343149
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg2366
- KEGG:   cgl:NCgl2075
- HOGENOM:   HBG478075
- OMA:   VNIVPEL
- PhylomeDB:   P94337
- ProtClustDB:   PRK09330
- BioCyc:   CGLU196627:CG2366-MONOMER
- GO:   GO:0005737
- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008
- Gene3D:   G3DSA:3.30.1330.20
- Gene3D:   G3DSA:3.40.50.1440
- PRINTS:   PR00423
- SMART:   SM00864
- SMART:   SM00865
- TIGRFAMs:   TIGR00065

Pfam domain/function: PF00091 Tubulin; SSF55307 Tub_FtsZ_C; SSF52490 Tubulin_FtsZ

EC number: NA

Molecular weight: Translated: 47215; Mature: 47084

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS01134 FTSZ_1; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPNNYLAKIKVVGVGGGGVNAVNRMIEEGLKGVEFIAVNTDSQALMFSDADVKLDIGR
CCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEEEECCC
EATRGLGAGANPEVGRASAEDHKNEIEETIKGADMVFVTAGEGGGTGTGAAPVVAGIAKK
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
MGALTIGVVTKPFEFEGRRRTRQAEEGIAALKEVCDTLIVIPNDRLLELGDANLSIMEAF
HCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCEEEECCCCHHHHHHH
RAADEVLHNGVQGITNLITIPGVINVDFADVRSVMSEAGSALMGVGSARGDNRVVSATEQ
HHHHHHHHHHHHHHHHHEECCCEEECCHHHHHHHHHHCCHHEEECCCCCCCCCEEHHHHH
AINSPLLEATMDGATGVLLSFAGGSDLGLMEVNAAASMVRERSDEDVNLIFGTIIDDNLG
HHCCCHHHHHCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCEEEEEEEEECCCCC
DEVRVTVIATGFDAARASAAENRRAGISAAPAAEPVQQQVPTTNATLPPEKESIFGGARE
CCEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCC
ENDPYLSRSAGARHRIEETRSGGGLFTTGNDRDYRRDERREDHRDERRDERRDDRSYDRR
CCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDRRDDRRDDRGDDLDVPSFLQ
HCCCHHCCCCCCCCCCCCHHCC
>Mature Secondary Structure 
TSPNNYLAKIKVVGVGGGGVNAVNRMIEEGLKGVEFIAVNTDSQALMFSDADVKLDIGR
CCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEEEECCC
EATRGLGAGANPEVGRASAEDHKNEIEETIKGADMVFVTAGEGGGTGTGAAPVVAGIAKK
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
MGALTIGVVTKPFEFEGRRRTRQAEEGIAALKEVCDTLIVIPNDRLLELGDANLSIMEAF
HCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCEEEECCCCHHHHHHH
RAADEVLHNGVQGITNLITIPGVINVDFADVRSVMSEAGSALMGVGSARGDNRVVSATEQ
HHHHHHHHHHHHHHHHHEECCCEEECCHHHHHHHHHHCCHHEEECCCCCCCCCEEHHHHH
AINSPLLEATMDGATGVLLSFAGGSDLGLMEVNAAASMVRERSDEDVNLIFGTIIDDNLG
HHCCCHHHHHCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCEEEEEEEEECCCCC
DEVRVTVIATGFDAARASAAENRRAGISAAPAAEPVQQQVPTTNATLPPEKESIFGGARE
CCEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCC
ENDPYLSRSAGARHRIEETRSGGGLFTTGNDRDYRRDERREDHRDERRDERRDDRSYDRR
CCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDRRDDRRDDRGDDLDVPSFLQ
HCCCHHCCCCCCCCCCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9240446; 9738885; 12948626