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The map label for this gene is ileS

Identifier: 62390987

GI number: 62390987

Start: 2242657

End: 2245821

Strand: Reverse

Name: ileS

Synonym: cg2359

Alternate gene names: 62390987

Gene position: 2245821-2242657 (Counterclockwise)

Preceding gene: 62390988

Following gene: 62390986

Centisome position: 68.41

GC content: 56.18

Gene sequence:

>3165_bases
ATGTCTGAAGCCGTTGGCGGAGTTTACCCACAGGTTGATTTATCTGGTGGGTCATCCAGATTTCCAGAGATGGAAGAGAA
TGTACTGAGCTACTGGAAGAAGGATGACACCTTCCAGGCCAGCATCGATCAGCGCGATGGTGCTGAAGACTACGTCTTTT
ACGATGGCCCTCCTTTTGCAAACGGTCTGCCACACTACGGCCACCTACTGACTGGTTACGTCAAGGACATTGTTCCTCGC
TACCAGACCATGCGTGGCTACCGCGTTCCTCGTGTCTTCGGTTGGGATACCCACGGTCTGCCAGCTGAACTTGAGGCTGA
AAAGCAGCTCGGCATCAAGGACAAGGGCGAGATCGAGGCCATGGGTCTTGCCAAGTTCAACGAGTACTGTGCAACCTCCG
TGTTGCAGTACACCAAGGAATGGGAAGAGTACGTCACCCGCCAGGCTCGTTGGGTGGACTTTGAAAACGGCTACAAGACC
ATGGACCTTTCTTTCATGGAGTCCGTGATCTGGGCGTTCAAGGAACTCTACGACAAGGGCCTGATCTACCAGGGTTTCCG
CGTTCTTCCTTACTCCTGGGCAGAGCACACCCCACTGTCCAACCAGGAAACCCGACTGGATGACTCCTACAAGCTGCGCC
AGGATCCAACCCTGACCGTCACGTTCCCAGTCACCGGTGTCGTCGAAGGTTCTTCTGCAAACGCTGGCCTGGTGGGAGCG
TTGGCTCTTGCGTGGACGACTACCCCGTGGACCCTTCCATCCAACCTTGCGTTGGCTGTGAACCCAGCGGTGACCTACGC
ATTGGTTGAGGTTGCTGAAGACGGTGAGGCAGAATTCGTCGGCAAGCGTGTGCTTTTGGCTAAGGACCTCGTTGGTTCCT
ACGCCAAGGAACTCGGTGCTGAGGCTGTTATCGTTTCTGAGCACCCAGGCTCTGAACTGGTCGGACTGACCTACGAGCCA
ATCTTTGGATATTTCCGCGATCACGCGAACGGATTCCAGATCCTCGGTGCAGAGTACGTCACCACCGAAGACGGCACCGG
TATCGTCCACCAGGCACCAGCTTTCGGTGAAGACGATATGAACACCTGTAACGCTGCCGGCATTGAGCCAGTCATCCCAG
TGGACATCGACGGCAAGTTCACCGGTTTGGTTCCTGAATACCAAGGTCAGCTTGTTTTCGATGCCAACAAGGACATCATC
AAGGACTTGAAGGCTGCAGGTCGCGTGGTTCGCCACCAGACCATCGAACACTCCTACCCACACTCTTGGCGTTCCGGTGA
GCCACTGATCTACATGGCTCTGCCATCTTGGTTTGTGAATGTCACCGAAATCCGCGACCGCATGGTTGAGGTCAACCAGG
ACATCGAGTGGATGCCAGCGCACATCCGCGACGGCCAGTTCGGCAAGTGGCTAGAAGGTGCCCGCGACTGGAACATCTCC
CGTTCCCGTTACTGGGGTTCACCAATTCCAGCATGGGTCTCCGACAACGACGAATACCCACGCGTTGATGTTTATGGTTC
CCTCGATGAGCTTGAGGCTGACTTTGGCGTGCGTCCAAAGTCCCTGCACCGTCCAGACATCGATGAACTAACTCGTCCAA
ACCCAGACGATCCAACCGGCAAGTCCACCATGCGACGCGTCACCGATGTTTTGGACGTGTGGTTCGACTCCGGTTCCATG
CCGTTTGCCCAGGTGCACTACCCATTCGAGAACAAAGAATGGTTTGATACCCACGCACCAGCAGACTTCATCGTGGAGTA
CATCGGTCAGACCCGCGGTTGGTTCTACCTGCTGCACGTGCTGTCCACCGCACTGTTTGACCGCCCAGCTTTCAAGAAGG
TTGTCGCACACGGCATCGTCTTGGGTGATGACGGACTGAAGATGTCCAAGTCCAAGGGCAACTACCCGAACGTCAACGAG
GTCTTCGACCGCGACGGTTCCGACGCCATGCGTTGGTTCCTCATGAGTTCCCCAATCCTGCGCGGCGGCAACTTGATTGT
CACCGAAAAGGGCATCCGCGAAGGTGTGCGCCAAGCACAGCTTCCAATGTGGAACGCATACTCCTTCCTGCAGCTGTACA
CCTCCAAGAACGCAACCTGGTCAGTCGACTCCACTGACGTGCTGGACCGCTACATCCTGGCGAAGCTGCACGATTTGGTG
GCAGAGACCCAGGCGGCACTCGACGGCACTGACATTGCAAAGGCTTGCGACTTGGTTCGTAACTTCTGTGATGCGTTGAC
CAACTGGTACGTGCGTCGTTCCCGCGACCGTTTCTGGGCTGGTGATGAAGCACACCCAGAGGCTTTCAACACCTTGTACA
CCGTGCTGGAAACCCTCACCCGCGTGGCAGCTCCACTGCTGCCAATGACCACCGAAGTGATCTGGCGTGGACTGACCGGC
GAGCGTTCTGTGCACCTGACTGATTTCCCATCCGCTGAGTCTTTCCCAGCAGATGCTGATTTGGTTCGCACCATGGATGA
GATCCGTGGCGTGTGCTCTGCGGCTTCCTCTGTTCGTAAGGCTCACAAGCTGCGTAACCGTCTGCCACTTCCAGGCCTGA
CTGTTGCTCTTCCAGACTCTGCTCGCCTGGCAGACTTCGCTTCGATCATCCGCGATGAGGTCAACGTGAAGAACGTGGAT
CTGACCTCTGACGTGGATTCCGTGGGAACCTTCGAGGTTGTTGTTAACGCTAAGGTTGCAGGTCCTCGCTTGGGCAAGGA
CGTCCAGCGCGTGATCAAGGCTGTGAAGGCTGGCAACTACACCCGCGAAGGCGACGTCGTTGTTGCCGATGGCATCGAGC
TCAACGAGGGTGAATTCACCGAGCGTCTCGTAGCAGCAAACCCTGATTCCACCGCGCAGATCGACGGCGTGGATGGACTC
GTGGTTCTGGACATGGAAGTCACGGAAGAACTTGAAGCAGAAGGCTGGGCAGCGGACGCGATCCGTGGCCTGCAGGATGC
TCGAAAGAACTCCGGCTTTGAGGTTTCTGACCGCATTTCTGTTGTCGTCAGCGTTCCTGAGGACAAGAAGGAATGGATCA
CCACTCACGCTGATCACATCGCAGCGGAAGTTTTGGCAACCTCCTTTGAGATCGTCACTGATGCCCTCGACGGCGAAACC
CACGACATTGTCGCTGGTGTGACCGCGAAGGTTACTAAGAACTAA

Upstream 100 bases:

>100_bases
TTTAGCTCAAGCTGGGTGGTACCGCGTCCGTTTTTTAGGGCGTCCCCGCAGGTAGAACGATAATTATTGTTACTTGCGTG
AAGGATGGGACCGAACACAC

Downstream 100 bases:

>100_bases
GAGTTGTTTTGTTGAGAAAGCCCGCTGCACATCGGTGTGGCGGGTTTTCTCATGCCCAGATATTGACCTTGTCACTGTGT
CAAGGCATTGAATAAGTGCC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1054; Mature: 1053

Protein sequence:

>1054_residues
MSEAVGGVYPQVDLSGGSSRFPEMEENVLSYWKKDDTFQASIDQRDGAEDYVFYDGPPFANGLPHYGHLLTGYVKDIVPR
YQTMRGYRVPRVFGWDTHGLPAELEAEKQLGIKDKGEIEAMGLAKFNEYCATSVLQYTKEWEEYVTRQARWVDFENGYKT
MDLSFMESVIWAFKELYDKGLIYQGFRVLPYSWAEHTPLSNQETRLDDSYKLRQDPTLTVTFPVTGVVEGSSANAGLVGA
LALAWTTTPWTLPSNLALAVNPAVTYALVEVAEDGEAEFVGKRVLLAKDLVGSYAKELGAEAVIVSEHPGSELVGLTYEP
IFGYFRDHANGFQILGAEYVTTEDGTGIVHQAPAFGEDDMNTCNAAGIEPVIPVDIDGKFTGLVPEYQGQLVFDANKDII
KDLKAAGRVVRHQTIEHSYPHSWRSGEPLIYMALPSWFVNVTEIRDRMVEVNQDIEWMPAHIRDGQFGKWLEGARDWNIS
RSRYWGSPIPAWVSDNDEYPRVDVYGSLDELEADFGVRPKSLHRPDIDELTRPNPDDPTGKSTMRRVTDVLDVWFDSGSM
PFAQVHYPFENKEWFDTHAPADFIVEYIGQTRGWFYLLHVLSTALFDRPAFKKVVAHGIVLGDDGLKMSKSKGNYPNVNE
VFDRDGSDAMRWFLMSSPILRGGNLIVTEKGIREGVRQAQLPMWNAYSFLQLYTSKNATWSVDSTDVLDRYILAKLHDLV
AETQAALDGTDIAKACDLVRNFCDALTNWYVRRSRDRFWAGDEAHPEAFNTLYTVLETLTRVAAPLLPMTTEVIWRGLTG
ERSVHLTDFPSAESFPADADLVRTMDEIRGVCSAASSVRKAHKLRNRLPLPGLTVALPDSARLADFASIIRDEVNVKNVD
LTSDVDSVGTFEVVVNAKVAGPRLGKDVQRVIKAVKAGNYTREGDVVVADGIELNEGEFTERLVAANPDSTAQIDGVDGL
VVLDMEVTEELEAEGWAADAIRGLQDARKNSGFEVSDRISVVVSVPEDKKEWITTHADHIAAEVLATSFEIVTDALDGET
HDIVAGVTAKVTKN

Sequences:

>Translated_1054_residues
MSEAVGGVYPQVDLSGGSSRFPEMEENVLSYWKKDDTFQASIDQRDGAEDYVFYDGPPFANGLPHYGHLLTGYVKDIVPR
YQTMRGYRVPRVFGWDTHGLPAELEAEKQLGIKDKGEIEAMGLAKFNEYCATSVLQYTKEWEEYVTRQARWVDFENGYKT
MDLSFMESVIWAFKELYDKGLIYQGFRVLPYSWAEHTPLSNQETRLDDSYKLRQDPTLTVTFPVTGVVEGSSANAGLVGA
LALAWTTTPWTLPSNLALAVNPAVTYALVEVAEDGEAEFVGKRVLLAKDLVGSYAKELGAEAVIVSEHPGSELVGLTYEP
IFGYFRDHANGFQILGAEYVTTEDGTGIVHQAPAFGEDDMNTCNAAGIEPVIPVDIDGKFTGLVPEYQGQLVFDANKDII
KDLKAAGRVVRHQTIEHSYPHSWRSGEPLIYMALPSWFVNVTEIRDRMVEVNQDIEWMPAHIRDGQFGKWLEGARDWNIS
RSRYWGSPIPAWVSDNDEYPRVDVYGSLDELEADFGVRPKSLHRPDIDELTRPNPDDPTGKSTMRRVTDVLDVWFDSGSM
PFAQVHYPFENKEWFDTHAPADFIVEYIGQTRGWFYLLHVLSTALFDRPAFKKVVAHGIVLGDDGLKMSKSKGNYPNVNE
VFDRDGSDAMRWFLMSSPILRGGNLIVTEKGIREGVRQAQLPMWNAYSFLQLYTSKNATWSVDSTDVLDRYILAKLHDLV
AETQAALDGTDIAKACDLVRNFCDALTNWYVRRSRDRFWAGDEAHPEAFNTLYTVLETLTRVAAPLLPMTTEVIWRGLTG
ERSVHLTDFPSAESFPADADLVRTMDEIRGVCSAASSVRKAHKLRNRLPLPGLTVALPDSARLADFASIIRDEVNVKNVD
LTSDVDSVGTFEVVVNAKVAGPRLGKDVQRVIKAVKAGNYTREGDVVVADGIELNEGEFTERLVAANPDSTAQIDGVDGL
VVLDMEVTEELEAEGWAADAIRGLQDARKNSGFEVSDRISVVVSVPEDKKEWITTHADHIAAEVLATSFEIVTDALDGET
HDIVAGVTAKVTKN
>Mature_1053_residues
SEAVGGVYPQVDLSGGSSRFPEMEENVLSYWKKDDTFQASIDQRDGAEDYVFYDGPPFANGLPHYGHLLTGYVKDIVPRY
QTMRGYRVPRVFGWDTHGLPAELEAEKQLGIKDKGEIEAMGLAKFNEYCATSVLQYTKEWEEYVTRQARWVDFENGYKTM
DLSFMESVIWAFKELYDKGLIYQGFRVLPYSWAEHTPLSNQETRLDDSYKLRQDPTLTVTFPVTGVVEGSSANAGLVGAL
ALAWTTTPWTLPSNLALAVNPAVTYALVEVAEDGEAEFVGKRVLLAKDLVGSYAKELGAEAVIVSEHPGSELVGLTYEPI
FGYFRDHANGFQILGAEYVTTEDGTGIVHQAPAFGEDDMNTCNAAGIEPVIPVDIDGKFTGLVPEYQGQLVFDANKDIIK
DLKAAGRVVRHQTIEHSYPHSWRSGEPLIYMALPSWFVNVTEIRDRMVEVNQDIEWMPAHIRDGQFGKWLEGARDWNISR
SRYWGSPIPAWVSDNDEYPRVDVYGSLDELEADFGVRPKSLHRPDIDELTRPNPDDPTGKSTMRRVTDVLDVWFDSGSMP
FAQVHYPFENKEWFDTHAPADFIVEYIGQTRGWFYLLHVLSTALFDRPAFKKVVAHGIVLGDDGLKMSKSKGNYPNVNEV
FDRDGSDAMRWFLMSSPILRGGNLIVTEKGIREGVRQAQLPMWNAYSFLQLYTSKNATWSVDSTDVLDRYILAKLHDLVA
ETQAALDGTDIAKACDLVRNFCDALTNWYVRRSRDRFWAGDEAHPEAFNTLYTVLETLTRVAAPLLPMTTEVIWRGLTGE
RSVHLTDFPSAESFPADADLVRTMDEIRGVCSAASSVRKAHKLRNRLPLPGLTVALPDSARLADFASIIRDEVNVKNVDL
TSDVDSVGTFEVVVNAKVAGPRLGKDVQRVIKAVKAGNYTREGDVVVADGIELNEGEFTERLVAANPDSTAQIDGVDGLV
VLDMEVTEELEAEGWAADAIRGLQDARKNSGFEVSDRISVVVSVPEDKKEWITTHADHIAAEVLATSFEIVTDALDGETH
DIVAGVTAKVTKN

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1028, Percent_Identity=39.2996108949416, Blast_Score=717, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1028, Percent_Identity=39.2996108949416, Blast_Score=717, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=791, Percent_Identity=28.8242730720607, Blast_Score=292, Evalue=1e-78,
Organism=Homo sapiens, GI268370297, Length=885, Percent_Identity=23.8418079096045, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI268370293, Length=885, Percent_Identity=23.8418079096045, Blast_Score=140, Evalue=6e-33,
Organism=Homo sapiens, GI268370295, Length=866, Percent_Identity=23.7875288683603, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI5454158, Length=821, Percent_Identity=23.020706455542, Blast_Score=125, Evalue=2e-28,
Organism=Escherichia coli, GI2367096, Length=805, Percent_Identity=29.4409937888199, Blast_Score=301, Evalue=2e-82,
Organism=Escherichia coli, GI1790708, Length=909, Percent_Identity=23.4323432343234, Blast_Score=153, Evalue=5e-38,
Organism=Escherichia coli, GI1786861, Length=190, Percent_Identity=27.3684210526316, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17541896, Length=1029, Percent_Identity=38.9698736637512, Blast_Score=687, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=808, Percent_Identity=27.1039603960396, Blast_Score=235, Evalue=9e-62,
Organism=Caenorhabditis elegans, GI72001587, Length=886, Percent_Identity=24.3792325056433, Blast_Score=146, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17510661, Length=526, Percent_Identity=24.1444866920152, Blast_Score=108, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1053, Percent_Identity=38.9363722697056, Blast_Score=701, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=795, Percent_Identity=26.6666666666667, Blast_Score=239, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6321531, Length=708, Percent_Identity=25.1412429378531, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28574730, Length=1075, Percent_Identity=37.8604651162791, Blast_Score=676, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1075, Percent_Identity=37.8604651162791, Blast_Score=676, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1075, Percent_Identity=37.8604651162791, Blast_Score=676, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=764, Percent_Identity=27.4869109947644, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI21355675, Length=647, Percent_Identity=25.0386398763524, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17864482, Length=607, Percent_Identity=23.3937397034596, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24653289, Length=607, Percent_Identity=23.3937397034596, Blast_Score=114, Evalue=3e-25,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_CORGL (Q8NNP0)

Other databases:

- EMBL:   BA000036
- EMBL:   BX927154
- RefSeq:   NP_601350.1
- RefSeq:   YP_226389.1
- ProteinModelPortal:   Q8NNP0
- SMR:   Q8NNP0
- GeneID:   1020100
- GeneID:   3345452
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg2359
- KEGG:   cgl:NCgl2068
- HOGENOM:   HBG577712
- OMA:   DCHGLPA
- PhylomeDB:   Q8NNP0
- ProtClustDB:   PRK06039
- BioCyc:   CGLU196627:CG2359-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 117405; Mature: 117274

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 630-630

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAVGGVYPQVDLSGGSSRFPEMEENVLSYWKKDDTFQASIDQRDGAEDYVFYDGPPFA
CCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECCCCCC
NGLPHYGHLLTGYVKDIVPRYQTMRGYRVPRVFGWDTHGLPAELEAEKQLGIKDKGEIEA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHCCCCCCCCEEE
MGLAKFNEYCATSVLQYTKEWEEYVTRQARWVDFENGYKTMDLSFMESVIWAFKELYDKG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEECHHHHHHHHHHHHHHHHCC
LIYQGFRVLPYSWAEHTPLSNQETRLDDSYKLRQDPTLTVTFPVTGVVEGSSANAGLVGA
CEECCCEECCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEEEEEEECCCCCCCHHHH
LALAWTTTPWTLPSNLALAVNPAVTYALVEVAEDGEAEFVGKRVLLAKDLVGSYAKELGA
HHHHEECCCCCCCCCCEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
EAVIVSEHPGSELVGLTYEPIFGYFRDHANGFQILGAEYVTTEDGTGIVHQAPAFGEDDM
CEEEEECCCCCCEEEEEHHHHHHHHHHCCCCEEEECCEEEECCCCCCEEECCCCCCCCCC
NTCNAAGIEPVIPVDIDGKFTGLVPEYQGQLVFDANKDIIKDLKAAGRVVRHQTIEHSYP
CCCCCCCCCCEEEEECCCCEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
HSWRSGEPLIYMALPSWFVNVTEIRDRMVEVNQDIEWMPAHIRDGQFGKWLEGARDWNIS
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
RSRYWGSPIPAWVSDNDEYPRVDVYGSLDELEADFGVRPKSLHRPDIDELTRPNPDDPTG
HHHCCCCCCCCCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCC
KSTMRRVTDVLDVWFDSGSMPFAQVHYPFENKEWFDTHAPADFIVEYIGQTRGWFYLLHV
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
LSTALFDRPAFKKVVAHGIVLGDDGLKMSKSKGNYPNVNEVFDRDGSDAMRWFLMSSPIL
HHHHHHCCHHHHHHHHCCEEECCCCCEECCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCC
RGGNLIVTEKGIREGVRQAQLPMWNAYSFLQLYTSKNATWSVDSTDVLDRYILAKLHDLV
CCCCEEEECHHHHHHHHHHCCCCCCHHHHHHHEECCCCEEECCCHHHHHHHHHHHHHHHH
AETQAALDGTDIAKACDLVRNFCDALTNWYVRRSRDRFWAGDEAHPEAFNTLYTVLETLT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVAAPLLPMTTEVIWRGLTGERSVHLTDFPSAESFPADADLVRTMDEIRGVCSAASSVRK
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AHKLRNRLPLPGLTVALPDSARLADFASIIRDEVNVKNVDLTSDVDSVGTFEVVVNAKVA
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEEEEEECC
GPRLGKDVQRVIKAVKAGNYTREGDVVVADGIELNEGEFTERLVAANPDSTAQIDGVDGL
CCCCCHHHHHHHHHHHCCCCCCCCCEEEECCEECCCCHHHHHHHCCCCCCCCEECCCCCE
VVLDMEVTEELEAEGWAADAIRGLQDARKNSGFEVSDRISVVVSVPEDKKEWITTHADHI
EEEEHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCHHHHHHHHHHHH
AAEVLATSFEIVTDALDGETHDIVAGVTAKVTKN
HHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECC
>Mature Secondary Structure 
SEAVGGVYPQVDLSGGSSRFPEMEENVLSYWKKDDTFQASIDQRDGAEDYVFYDGPPFA
CCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECCCCCC
NGLPHYGHLLTGYVKDIVPRYQTMRGYRVPRVFGWDTHGLPAELEAEKQLGIKDKGEIEA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHCCCCCCCCEEE
MGLAKFNEYCATSVLQYTKEWEEYVTRQARWVDFENGYKTMDLSFMESVIWAFKELYDKG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEECHHHHHHHHHHHHHHHHCC
LIYQGFRVLPYSWAEHTPLSNQETRLDDSYKLRQDPTLTVTFPVTGVVEGSSANAGLVGA
CEECCCEECCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEEEEEEECCCCCCCHHHH
LALAWTTTPWTLPSNLALAVNPAVTYALVEVAEDGEAEFVGKRVLLAKDLVGSYAKELGA
HHHHEECCCCCCCCCCEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
EAVIVSEHPGSELVGLTYEPIFGYFRDHANGFQILGAEYVTTEDGTGIVHQAPAFGEDDM
CEEEEECCCCCCEEEEEHHHHHHHHHHCCCCEEEECCEEEECCCCCCEEECCCCCCCCCC
NTCNAAGIEPVIPVDIDGKFTGLVPEYQGQLVFDANKDIIKDLKAAGRVVRHQTIEHSYP
CCCCCCCCCCEEEEECCCCEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
HSWRSGEPLIYMALPSWFVNVTEIRDRMVEVNQDIEWMPAHIRDGQFGKWLEGARDWNIS
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
RSRYWGSPIPAWVSDNDEYPRVDVYGSLDELEADFGVRPKSLHRPDIDELTRPNPDDPTG
HHHCCCCCCCCCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCC
KSTMRRVTDVLDVWFDSGSMPFAQVHYPFENKEWFDTHAPADFIVEYIGQTRGWFYLLHV
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
LSTALFDRPAFKKVVAHGIVLGDDGLKMSKSKGNYPNVNEVFDRDGSDAMRWFLMSSPIL
HHHHHHCCHHHHHHHHCCEEECCCCCEECCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCC
RGGNLIVTEKGIREGVRQAQLPMWNAYSFLQLYTSKNATWSVDSTDVLDRYILAKLHDLV
CCCCEEEECHHHHHHHHHHCCCCCCHHHHHHHEECCCCEEECCCHHHHHHHHHHHHHHHH
AETQAALDGTDIAKACDLVRNFCDALTNWYVRRSRDRFWAGDEAHPEAFNTLYTVLETLT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVAAPLLPMTTEVIWRGLTGERSVHLTDFPSAESFPADADLVRTMDEIRGVCSAASSVRK
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AHKLRNRLPLPGLTVALPDSARLADFASIIRDEVNVKNVDLTSDVDSVGTFEVVVNAKVA
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEEEEEECC
GPRLGKDVQRVIKAVKAGNYTREGDVVVADGIELNEGEFTERLVAANPDSTAQIDGVDGL
CCCCCHHHHHHHHHHHCCCCCCCCCEEEECCEECCCCHHHHHHHCCCCCCCCEECCCCCE
VVLDMEVTEELEAEGWAADAIRGLQDARKNSGFEVSDRISVVVSVPEDKKEWITTHADHI
EEEEHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCHHHHHHHHHHHH
AAEVLATSFEIVTDALDGETHDIVAGVTAKVTKN
HHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626