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The map label for this gene is dinP [H]

Identifier: 62390983

GI number: 62390983

Start: 2238566

End: 2239969

Strand: Reverse

Name: dinP [H]

Synonym: cg2355

Alternate gene names: 62390983

Gene position: 2239969-2238566 (Counterclockwise)

Preceding gene: 62390984

Following gene: 62390982

Centisome position: 68.24

GC content: 54.34

Gene sequence:

>1404_bases
ATGCAACGCTGGGTGCTTCACATCGATATGGATGCCTTCTTCGCATCCTGCGAACAACTGACCCGGCCCACTTTAAGAGG
CCGCCCCGTCTTGGTCGGTGGAGTCTCCGGTAGGGGAGTTGTCGCCGGAGCATCCTATGAAGCCAGAAAATTTGGCGCCC
GCTCAGCGATGCCCATGCACCAAGCCAAAGCCCGAGTAGGTTTTGGGGCAGTGGTGGTGACACCCCGTCATATCGTTTAC
TCCGCAGCCTCGCGCCGGGTGTTCCAAATCGTGGAAAAACGCGCCGGAATTGTCGAACGCCTCAGCATCGATGAAGGCTT
CATGGAACCAGAGGCTCTCGTTGGAGCCACCCCAGAAGAGGTGAAACAGTGGGCGGAAGAATTACGCGCGGAAATTAAAG
AAGTTACTGGCTTACCCTCCTCGGTTGGTGCTGGCTCCGGTAAGCAGATCGCCAAAATTGGTTCAGGCGAAGCAAAGCCA
GATGGTGTGTTTGTCGTGCCAGTAGACAAGCAACATGACTTGCTTGATCCACTTCCTGTGGGCGCACTTTGGGGAGTGGG
TCCTGTGACAGGCTCCAAGCTTGCCTCAATGGGGGTGGAAACAATTGGTGATCTAGCAGCGCTAACCCAAAAAGAAGTAG
AAATCAGCCTCGGTGCAACCATCGGAATATCACTGTGGAACCTTGCCCGAGGAATCGACGACCGCCCTGTGGAACCCCGC
GCCGAAGCAAAACAGATCTCCCAAGAGCACACCTATGAAAAAGACCTCCTCACCAGGCAACAAGTAGATGCTGCCATCAT
TCGATCAGCCGAAGGCGCACACCGACGGCTCCTCAAAGACGGACGCGGTGCCAGAACTGTCAGCGTGAAACTGCGGATGG
CCGACTTTCGTATTGAGTCTCGTTCCTACACCTTGTCCTATGCCACCGATGATTACGCAACTCTTGAGGCAACAGCATTC
CGACTTGCCCGCTACCCCGGAGAAGTAGGCCCCATCCGCCTTGTCGGAGTAAGTTTTTCTGGTTTGGAAGAATCCCGCCA
AGACATCCTCTTCCCGGAACTTGACCAACAAATCATCGTACCACCAGCACCCGACACCGATTATGAGGTAGGCGTGCAAT
CCTCTTCTAGTTCCGAAAGTACTCAAGTTGAAGCGCCGCAAGATGTCGCGTTGAGTATGTGGTGCGCAACGCAAGATGTC
TACCACCCAGAATATGGCCACGGTTGGGTACAAGGTGCCGGTCACGGTGTTGTATCAGTACGTTTTGAAACCCGCAGCAC
CACAAAAGGGCGAACTAAAAGTTTTTCCATGGATGACCCGGACCTCACCCCGGCAGACCCTCTAGATAGTTTGGATTGGG
CTGACTGGTTTGCTGAAAATGGTGAAACGGGGGATGACGAATAG

Upstream 100 bases:

>100_bases
ACGCCCCTCCTAGCGGTTTCCCACACCGCCAGTCTTCTCAAACTAATCGTTGACCTGTTCGATTAACCTAATTTTCGGCT
GGTCAACTACCATAAAAAGC

Downstream 100 bases:

>100_bases
GGTTTCATCGGGTTTCGGGGTGCTTTTGGGCGGTGGTTGCCCATGAATAGACGCAAAGGGAAAGAATGTTCTAATATTCA
CCACAAATTGCTGCCGAAAG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MQRWVLHIDMDAFFASCEQLTRPTLRGRPVLVGGVSGRGVVAGASYEARKFGARSAMPMHQAKARVGFGAVVVTPRHIVY
SAASRRVFQIVEKRAGIVERLSIDEGFMEPEALVGATPEEVKQWAEELRAEIKEVTGLPSSVGAGSGKQIAKIGSGEAKP
DGVFVVPVDKQHDLLDPLPVGALWGVGPVTGSKLASMGVETIGDLAALTQKEVEISLGATIGISLWNLARGIDDRPVEPR
AEAKQISQEHTYEKDLLTRQQVDAAIIRSAEGAHRRLLKDGRGARTVSVKLRMADFRIESRSYTLSYATDDYATLEATAF
RLARYPGEVGPIRLVGVSFSGLEESRQDILFPELDQQIIVPPAPDTDYEVGVQSSSSSESTQVEAPQDVALSMWCATQDV
YHPEYGHGWVQGAGHGVVSVRFETRSTTKGRTKSFSMDDPDLTPADPLDSLDWADWFAENGETGDDE

Sequences:

>Translated_467_residues
MQRWVLHIDMDAFFASCEQLTRPTLRGRPVLVGGVSGRGVVAGASYEARKFGARSAMPMHQAKARVGFGAVVVTPRHIVY
SAASRRVFQIVEKRAGIVERLSIDEGFMEPEALVGATPEEVKQWAEELRAEIKEVTGLPSSVGAGSGKQIAKIGSGEAKP
DGVFVVPVDKQHDLLDPLPVGALWGVGPVTGSKLASMGVETIGDLAALTQKEVEISLGATIGISLWNLARGIDDRPVEPR
AEAKQISQEHTYEKDLLTRQQVDAAIIRSAEGAHRRLLKDGRGARTVSVKLRMADFRIESRSYTLSYATDDYATLEATAF
RLARYPGEVGPIRLVGVSFSGLEESRQDILFPELDQQIIVPPAPDTDYEVGVQSSSSSESTQVEAPQDVALSMWCATQDV
YHPEYGHGWVQGAGHGVVSVRFETRSTTKGRTKSFSMDDPDLTPADPLDSLDWADWFAENGETGDDE
>Mature_467_residues
MQRWVLHIDMDAFFASCEQLTRPTLRGRPVLVGGVSGRGVVAGASYEARKFGARSAMPMHQAKARVGFGAVVVTPRHIVY
SAASRRVFQIVEKRAGIVERLSIDEGFMEPEALVGATPEEVKQWAEELRAEIKEVTGLPSSVGAGSGKQIAKIGSGEAKP
DGVFVVPVDKQHDLLDPLPVGALWGVGPVTGSKLASMGVETIGDLAALTQKEVEISLGATIGISLWNLARGIDDRPVEPR
AEAKQISQEHTYEKDLLTRQQVDAAIIRSAEGAHRRLLKDGRGARTVSVKLRMADFRIESRSYTLSYATDDYATLEATAF
RLARYPGEVGPIRLVGVSFSGLEESRQDILFPELDQQIIVPPAPDTDYEVGVQSSSSSESTQVEAPQDVALSMWCATQDV
YHPEYGHGWVQGAGHGVVSVRFETRSTTKGRTKSFSMDDPDLTPADPLDSLDWADWFAENGETGDDE

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=377, Percent_Identity=26.790450928382, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI7706681, Length=378, Percent_Identity=26.7195767195767, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI7705344, Length=158, Percent_Identity=31.0126582278481, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI5729982, Length=213, Percent_Identity=27.6995305164319, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1786425, Length=364, Percent_Identity=31.5934065934066, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787432, Length=305, Percent_Identity=27.5409836065574, Blast_Score=98, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17537959, Length=368, Percent_Identity=25.2717391304348, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115534089, Length=336, Percent_Identity=27.0833333333333, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193205700, Length=223, Percent_Identity=31.8385650224215, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193205702, Length=223, Percent_Identity=31.8385650224215, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19923006, Length=415, Percent_Identity=26.2650602409639, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24668444, Length=135, Percent_Identity=31.1111111111111, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 50689; Mature: 50689

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRWVLHIDMDAFFASCEQLTRPTLRGRPVLVGGVSGRGVVAGASYEARKFGARSAMPMH
CCEEEEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCCHHHHHCCCCCCCHH
QAKARVGFGAVVVTPRHIVYSAASRRVFQIVEKRAGIVERLSIDEGFMEPEALVGATPEE
HHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHCCCHHH
VKQWAEELRAEIKEVTGLPSSVGAGSGKQIAKIGSGEAKPDGVFVVPVDKQHDLLDPLPV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCC
GALWGVGPVTGSKLASMGVETIGDLAALTQKEVEISLGATIGISLWNLARGIDDRPVEPR
CHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEHHHHHHHHCCCCCCCCCCC
AEAKQISQEHTYEKDLLTRQQVDAAIIRSAEGAHRRLLKDGRGARTVSVKLRMADFRIES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEEEEEEEEEC
RSYTLSYATDDYATLEATAFRLARYPGEVGPIRLVGVSFSGLEESRQDILFPELDQQIIV
CEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCEEEE
PPAPDTDYEVGVQSSSSSESTQVEAPQDVALSMWCATQDVYHPEYGHGWVQGAGHGVVSV
CCCCCCCCEECCCCCCCCCCCCCCCCHHHEEEEEEHHCCCCCCCCCCCEEECCCCCEEEE
RFETRSTTKGRTKSFSMDDPDLTPADPLDSLDWADWFAENGETGDDE
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQRWVLHIDMDAFFASCEQLTRPTLRGRPVLVGGVSGRGVVAGASYEARKFGARSAMPMH
CCEEEEEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCCHHHHHCCCCCCCHH
QAKARVGFGAVVVTPRHIVYSAASRRVFQIVEKRAGIVERLSIDEGFMEPEALVGATPEE
HHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHCCCHHH
VKQWAEELRAEIKEVTGLPSSVGAGSGKQIAKIGSGEAKPDGVFVVPVDKQHDLLDPLPV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCC
GALWGVGPVTGSKLASMGVETIGDLAALTQKEVEISLGATIGISLWNLARGIDDRPVEPR
CHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEHHHHHHHHCCCCCCCCCCC
AEAKQISQEHTYEKDLLTRQQVDAAIIRSAEGAHRRLLKDGRGARTVSVKLRMADFRIES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEEEEEEEEEC
RSYTLSYATDDYATLEATAFRLARYPGEVGPIRLVGVSFSGLEESRQDILFPELDQQIIV
CEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCEEEE
PPAPDTDYEVGVQSSSSSESTQVEAPQDVALSMWCATQDVYHPEYGHGWVQGAGHGVVSV
CCCCCCCCEECCCCCCCCCCCCCCCCHHHEEEEEEHHCCCCCCCCCCCEEECCCCCEEEE
RFETRSTTKGRTKSFSMDDPDLTPADPLDSLDWADWFAENGETGDDE
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA