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The map label for this gene is lspA [H]

Identifier: 62390975

GI number: 62390975

Start: 2230964

End: 2231536

Strand: Reverse

Name: lspA [H]

Synonym: cg2347

Alternate gene names: 62390975

Gene position: 2231536-2230964 (Counterclockwise)

Preceding gene: 62390978

Following gene: 62390974

Centisome position: 67.98

GC content: 51.13

Gene sequence:

>573_bases
GTGACCTCAAAGGATGCAGGGGCAAACGTGACCCCCATGAGTAAGAAAGAAAAGAGGACAACCGTTAAACAGGTGGTTGC
CTTGATGGCCGCCATCGTTGTGGTGATTGCGTCCCTAGACCAAATAGTCAAGCAGATTATGCTTAGTTGGTTGGAACCTG
GCGTTCCCGTTCCCATCATTGGGGATTGGTTCCGCTTCTACCTCCTGTTTAACCCCGGAGCCGCATTTTCGATGGGTGGG
GAAAACAGCACCTGGATCTTTACAACCATCCAGTTGAGCTTCGTCATCGGTATCGCAATTTATGCCCCACGCATCAAACA
CAAGTGGATCGCGGCAGGACTTGCCCTTGTTGCCGGTGGAGCCTTGGGAAACGTGTTGGACCGGTTGTTCAGAGATCCTT
CCTTCTTCTTCGGACATGTTGTTGATTACATCTCCGTAGGAAACTTTGCAGTATTTAATATCGCCGATGCCTCGATTTCT
TGCGGCGTCGTGGTGTTCCTGATCGGAATGTTCCTTGAGGACCGTGAAAACGCCCAGCATGCCAAAGCAACTGACGAGAA
GGATGAGGCCTGA

Upstream 100 bases:

>100_bases
CTGCAACTGTGTAAAAACCAGCGCTGAATTAAAGATCACCTTTCACCCTTAATTGAGCCTGGGTGGAAGTTTCTACCGCT
CATGGGGAAAGATGGTCAAC

Downstream 100 bases:

>100_bases
TGAACAACCGACAAAGCAGAACCCTTCCCGTACCAGAAGGACTGGCAGGCATGCGTGTGGACGCAGCACTGTCCAAGTTG
CTGGGAATTTCACGCACCGT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MTSKDAGANVTPMSKKEKRTTVKQVVALMAAIVVVIASLDQIVKQIMLSWLEPGVPVPIIGDWFRFYLLFNPGAAFSMGG
ENSTWIFTTIQLSFVIGIAIYAPRIKHKWIAAGLALVAGGALGNVLDRLFRDPSFFFGHVVDYISVGNFAVFNIADASIS
CGVVVFLIGMFLEDRENAQHAKATDEKDEA

Sequences:

>Translated_190_residues
MTSKDAGANVTPMSKKEKRTTVKQVVALMAAIVVVIASLDQIVKQIMLSWLEPGVPVPIIGDWFRFYLLFNPGAAFSMGG
ENSTWIFTTIQLSFVIGIAIYAPRIKHKWIAAGLALVAGGALGNVLDRLFRDPSFFFGHVVDYISVGNFAVFNIADASIS
CGVVVFLIGMFLEDRENAQHAKATDEKDEA
>Mature_189_residues
TSKDAGANVTPMSKKEKRTTVKQVVALMAAIVVVIASLDQIVKQIMLSWLEPGVPVPIIGDWFRFYLLFNPGAAFSMGGE
NSTWIFTTIQLSFVIGIAIYAPRIKHKWIAAGLALVAGGALGNVLDRLFRDPSFFFGHVVDYISVGNFAVFNIADASISC
GVVVFLIGMFLEDRENAQHAKATDEKDEA

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 20684; Mature: 20553

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00855 SPASE_II ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKDAGANVTPMSKKEKRTTVKQVVALMAAIVVVIASLDQIVKQIMLSWLEPGVPVPII
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
GDWFRFYLLFNPGAAFSMGGENSTWIFTTIQLSFVIGIAIYAPRIKHKWIAAGLALVAGG
HHHHHHHHEECCCCEEECCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
ALGNVLDRLFRDPSFFFGHVVDYISVGNFAVFNIADASISCGVVVFLIGMFLEDRENAQH
HHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHH
AKATDEKDEA
HCCCCCCCCC
>Mature Secondary Structure 
TSKDAGANVTPMSKKEKRTTVKQVVALMAAIVVVIASLDQIVKQIMLSWLEPGVPVPII
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
GDWFRFYLLFNPGAAFSMGGENSTWIFTTIQLSFVIGIAIYAPRIKHKWIAAGLALVAGG
HHHHHHHHEECCCCEEECCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
ALGNVLDRLFRDPSFFFGHVVDYISVGNFAVFNIADASISCGVVVFLIGMFLEDRENAQH
HHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHH
AKATDEKDEA
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA