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The map label for this gene is tsf [H]

Identifier: 62390864

GI number: 62390864

Start: 2109050

End: 2109877

Strand: Reverse

Name: tsf [H]

Synonym: cg2221

Alternate gene names: 62390864

Gene position: 2109877-2109050 (Counterclockwise)

Preceding gene: 62390865

Following gene: 62390863

Centisome position: 64.27

GC content: 56.88

Gene sequence:

>828_bases
ATGGCGAACTACACCGCTGCGGATGTTAAGAAGCTCCGCGAACTCACCGGTTCCGGCATGCTCGATTGCAAGAAGGCTCT
GGAGGAGTCCGCTGGCGACTTCGACAAGGCTGTTGAGATCCTGCGCGTCAAGGGCGCAAAGGACGTCGGAAAGCGTGCAG
AGCGTAACGCTACCGAAGGTCTCGTTGCAGTTTCTGGCAACACCATGGTCGAGGTCAACTCTGAGACCGACTTCGTTGCA
AAGAACTCTGACTTCAAGGAATTCGCTGCAAAGGTTGCAGACGCAGCAGCAGCTGCAAAGGCTAACTCCCAGGAAGAGCT
CGCAGCAGTTGACGTGGACGGACAGACCGCAGACGCAGCTCTGCAGGAGTTCTCCGCAAAGATCGGCGAGAAGCTTGAGC
TTCGTCGCGCAGTAACCCTCGAGGGCGACAAGACCGCTGTTTACCTCCACCAGCGTTCCGCTGACCTGCCACCAGCAGTT
GGCGTTTTGGTTGCTTTCACCGGTGAAGGTGAAGCAGCTGAGGCAGCTGCACGTCAGGCTGCAATGCAGATTGCTGCTCT
GAAGGCTTCTTACCTCACCCGTGAGGACGTTCCTGCAGAGATCATCGAGAAGGAGCGCTCCATCGCTGAGCAGATCACTC
GCGAAGAGGGCAAGCCAGAGCAGGCTATCCCTAAGATCGTTGAGGGTCGTTTGAATGGCTTCTACAAGGAGAACGTACTT
CTTGAGCAGTCCTCGGTAGCTGACAGCAAGAAGACCGTTAAGGCTCTTCTGGACGAGGCTGGCGTTACCGTCACCTCCTT
CGCTCGCTTCGAGGTCGGCCAGGCTTAA

Upstream 100 bases:

>100_bases
ACCTGTACGATCACTTTTTAGACGGGCGGGTAGGGCTACTGTGCCCTAACCTAAGCTTGTAAAGCATTAATTATCCATAC
ATAAGGAGGATCGCCCCGTA

Downstream 100 bases:

>100_bases
GGCCACTTGAAGGTTGTGGGTGGGTGTCTGTTGATCCCCACCTCGCCTTTTTAAGTTTTGAAAAAGACTTAAACACTTTA
GAAGGTTGCCCCGCGCATCG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MANYTAADVKKLRELTGSGMLDCKKALEESAGDFDKAVEILRVKGAKDVGKRAERNATEGLVAVSGNTMVEVNSETDFVA
KNSDFKEFAAKVADAAAAAKANSQEELAAVDVDGQTADAALQEFSAKIGEKLELRRAVTLEGDKTAVYLHQRSADLPPAV
GVLVAFTGEGEAAEAAARQAAMQIAALKASYLTREDVPAEIIEKERSIAEQITREEGKPEQAIPKIVEGRLNGFYKENVL
LEQSSVADSKKTVKALLDEAGVTVTSFARFEVGQA

Sequences:

>Translated_275_residues
MANYTAADVKKLRELTGSGMLDCKKALEESAGDFDKAVEILRVKGAKDVGKRAERNATEGLVAVSGNTMVEVNSETDFVA
KNSDFKEFAAKVADAAAAAKANSQEELAAVDVDGQTADAALQEFSAKIGEKLELRRAVTLEGDKTAVYLHQRSADLPPAV
GVLVAFTGEGEAAEAAARQAAMQIAALKASYLTREDVPAEIIEKERSIAEQITREEGKPEQAIPKIVEGRLNGFYKENVL
LEQSSVADSKKTVKALLDEAGVTVTSFARFEVGQA
>Mature_274_residues
ANYTAADVKKLRELTGSGMLDCKKALEESAGDFDKAVEILRVKGAKDVGKRAERNATEGLVAVSGNTMVEVNSETDFVAK
NSDFKEFAAKVADAAAAAKANSQEELAAVDVDGQTADAALQEFSAKIGEKLELRRAVTLEGDKTAVYLHQRSADLPPAVG
VLVAFTGEGEAAEAAARQAAMQIAALKASYLTREDVPAEIIEKERSIAEQITREEGKPEQAIPKIVEGRLNGFYKENVLL
EQSSVADSKKTVKALLDEAGVTVTSFARFEVGQA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Escherichia coli, GI1786366, Length=278, Percent_Identity=42.4460431654676, Blast_Score=178, Evalue=3e-46,
Organism=Drosophila melanogaster, GI19921466, Length=291, Percent_Identity=29.2096219931272, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 29280; Mature: 29149

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYTAADVKKLRELTGSGMLDCKKALEESAGDFDKAVEILRVKGAKDVGKRAERNATEG
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCCHHCC
LVAVSGNTMVEVNSETDFVAKNSDFKEFAAKVADAAAAAKANSQEELAAVDVDGQTADAA
EEEECCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHH
LQEFSAKIGEKLELRRAVTLEGDKTAVYLHQRSADLPPAVGVLVAFTGEGEAAEAAARQA
HHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHH
AMQIAALKASYLTREDVPAEIIEKERSIAEQITREEGKPEQAIPKIVEGRLNGFYKENVL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCEE
LEQSSVADSKKTVKALLDEAGVTVTSFARFEVGQA
EEHHHHHHHHHHHHHHHHHCCCEEHHHHHHHCCCC
>Mature Secondary Structure 
ANYTAADVKKLRELTGSGMLDCKKALEESAGDFDKAVEILRVKGAKDVGKRAERNATEG
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCCHHCC
LVAVSGNTMVEVNSETDFVAKNSDFKEFAAKVADAAAAAKANSQEELAAVDVDGQTADAA
EEEECCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHH
LQEFSAKIGEKLELRRAVTLEGDKTAVYLHQRSADLPPAVGVLVAFTGEGEAAEAAARQA
HHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHH
AMQIAALKASYLTREDVPAEIIEKERSIAEQITREEGKPEQAIPKIVEGRLNGFYKENVL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCEE
LEQSSVADSKKTVKALLDEAGVTVTSFARFEVGQA
EEHHHHHHHHHHHHHHHHHCCCEEHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]