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The map label for this gene is frr [H]

Identifier: 62390862

GI number: 62390862

Start: 2107333

End: 2107890

Strand: Reverse

Name: frr [H]

Synonym: cg2217

Alternate gene names: 62390862

Gene position: 2107890-2107333 (Counterclockwise)

Preceding gene: 62390863

Following gene: 62390861

Centisome position: 64.21

GC content: 51.79

Gene sequence:

>558_bases
ATGATTGATGAAATTCTGTTCGAAGCGGAAGAGCGCATGACCGCAACGGTCGAGCACACCCGCGAAGACTTGACCACCAT
TCGTACCGGTCGCGCAAACCCGGCTATGTTCAACGGTGTCATGGCTGAATACTACGGCGTGCCTACTCCTATTACTCAGA
TGTCAGGCATCACTGTTCCAGAGCCTCGCATGCTGCTGATCAAGCCTTATGAGATGTCTTCCATGCAGGTCATTGAGAAT
GCTATCCGTAACTCTGACCTTGGTGTTAACCCCACCAACGATGGCCAGGTGCTGCGTGTGACCATCCCACAGCTTACTGA
AGAGCGTCGTAAGGACATGGTCAAGCTTGCTAAGGGTAAGGGCGAAGACGGCAAGATTGCCATTCGTAACATCCGCCGCA
AGGGCATGGACCAGCTAAAGAAGCTGCAAAAAGATGGCGACGCTGGCGAAGATGAAGTACAGGCAGCAGAAAAAGAACTA
GATAAAGTCACCGCTGGTTTTGTTGCGCAGGTCGATGAAGTCGTTGCTCGCAAGGAAAAGGAACTGATGGAGGTCTAG

Upstream 100 bases:

>100_bases
AGTCCTGATACATTTAGTCTTATAAACAGCGTGGCTTATCTAGGTTCGATTCTAGGATCCATCAGAATCCACGCTGTTAG
AAAAACACAGGAGTGAATAA

Downstream 100 bases:

>100_bases
AAGACCTTTATCGCAATGGCTTAAGAATTACGTCGTTTCAACGTCGATTGGGCGGGGAAACGACGCTTTCTTTTGCTTGC
AAGAGTGTTTGGAAGAATTT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIDEILFEAEERMTATVEHTREDLTTIRTGRANPAMFNGVMAEYYGVPTPITQMSGITVPEPRMLLIKPYEMSSMQVIEN
AIRNSDLGVNPTNDGQVLRVTIPQLTEERRKDMVKLAKGKGEDGKIAIRNIRRKGMDQLKKLQKDGDAGEDEVQAAEKEL
DKVTAGFVAQVDEVVARKEKELMEV

Sequences:

>Translated_185_residues
MIDEILFEAEERMTATVEHTREDLTTIRTGRANPAMFNGVMAEYYGVPTPITQMSGITVPEPRMLLIKPYEMSSMQVIEN
AIRNSDLGVNPTNDGQVLRVTIPQLTEERRKDMVKLAKGKGEDGKIAIRNIRRKGMDQLKKLQKDGDAGEDEVQAAEKEL
DKVTAGFVAQVDEVVARKEKELMEV
>Mature_185_residues
MIDEILFEAEERMTATVEHTREDLTTIRTGRANPAMFNGVMAEYYGVPTPITQMSGITVPEPRMLLIKPYEMSSMQVIEN
AIRNSDLGVNPTNDGQVLRVTIPQLTEERRKDMVKLAKGKGEDGKIAIRNIRRKGMDQLKKLQKDGDAGEDEVQAAEKEL
DKVTAGFVAQVDEVVARKEKELMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=30, Blast_Score=80, Evalue=7e-16,
Organism=Homo sapiens, GI291042689, Length=135, Percent_Identity=34.8148148148148, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=40.7608695652174, Blast_Score=159, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=23.6994219653179, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20749; Mature: 20749

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDEILFEAEERMTATVEHTREDLTTIRTGRANPAMFNGVMAEYYGVPTPITQMSGITVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCC
EPRMLLIKPYEMSSMQVIENAIRNSDLGVNPTNDGQVLRVTIPQLTEERRKDMVKLAKGK
CCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCC
GEDGKIAIRNIRRKGMDQLKKLQKDGDAGEDEVQAAEKELDKVTAGFVAQVDEVVARKEK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC
>Mature Secondary Structure
MIDEILFEAEERMTATVEHTREDLTTIRTGRANPAMFNGVMAEYYGVPTPITQMSGITVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCC
EPRMLLIKPYEMSSMQVIENAIRNSDLGVNPTNDGQVLRVTIPQLTEERRKDMVKLAKGK
CCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCC
GEDGKIAIRNIRRKGMDQLKKLQKDGDAGEDEVQAAEKELDKVTAGFVAQVDEVVARKEK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA