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The map label for this gene is 62390836

Identifier: 62390836

GI number: 62390836

Start: 2078436

End: 2079197

Strand: Reverse

Name: 62390836

Synonym: cg2187

Alternate gene names: NA

Gene position: 2079197-2078436 (Counterclockwise)

Preceding gene: 62390837

Following gene: 62390834

Centisome position: 63.34

GC content: 60.24

Gene sequence:

>762_bases
TTGCGCCTGGCGTCCATGGGGGAGGAGGACTCCACCCCAGGTAGGCGTTCCAAGGCGTATTCGCGCCAGGGCGCTGATGT
CCGCCCCATGAAGGGTGGACACGGCATCAACTTAGTGGGCACGCTCATGGCGGCTACGGAACGCGGCGCCAACATTGTTG
AAGGCGTGGTCGATTTCCGGCCCACGGACCTGCGGGGTTCGCTGCGCCGTGGGCGCGAAGCCAACCTCATCGTGTTCGTC
GTCGACACATCGGGGTCGATGGCTGCGCGTTCCAGGGTGCGTGCGGTCACCGGGACTATTACCTCTATGCTTAACGACGC
CTACCAGCGCCGCGACAAGGTTGCGGTTATCGCGGTCAACGGCAACAAGCCGACACTGGTGTTGAATCCAACAAATTCTG
TGGAGCAAGCTCAGCAGAAATTAAAGGATATGCCGATGGGTGGTCGCACTCCACTGGCAGAGGGGCTGCTCATGGCCAAG
GATCTCATGGCAAGGGAACTCCGAAAGGAACCCGGCCGACGCGCGATCCTCATGGTGATGACCGATGGCCAAGACACCTC
CGATGCCGGCGAAGCAGGCATTGCCACCGCGGCGGAAACAGTGGTGAAATCACGACTGTCCGGCAACGTGGTCATCGACT
GCGAAGGCCGACTCAAAGTGCGCAAAGAGCGCGCCGGGGTGTTGGCTGAAATGCTCGGTGGTGTGTGCGTGAGATTGCGT
GATCTTAACTCCGAGCACATCAAAATGGTGATTAACGCCTAG

Upstream 100 bases:

>100_bases
ACCGAGGAAGACGGTCTGCAAGGAACTGCGCAGGCGAAGGCGCAGACTACTGGAAAGGTAGGTACTGCCGGATCCGGCGA
CCCCTTTCGCTCCTAGGCAT

Downstream 100 bases:

>100_bases
ACAACCAGAGTGAGGGTTTCCTTGTGGTTGGGGTTTTCCTCCACCACAAGGCCCGCAGCCTGCGCAATGCTCATTACGTC
CTCTGCGTTGTGTGCTTCTT

Product: Mg-chelatase subunit D

Products: ADP; phosphate; Mg-protoporphyrin IX; H+

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRLASMGEEDSTPGRRSKAYSRQGADVRPMKGGHGINLVGTLMAATERGANIVEGVVDFRPTDLRGSLRRGREANLIVFV
VDTSGSMAARSRVRAVTGTITSMLNDAYQRRDKVAVIAVNGNKPTLVLNPTNSVEQAQQKLKDMPMGGRTPLAEGLLMAK
DLMARELRKEPGRRAILMVMTDGQDTSDAGEAGIATAAETVVKSRLSGNVVIDCEGRLKVRKERAGVLAEMLGGVCVRLR
DLNSEHIKMVINA

Sequences:

>Translated_253_residues
MRLASMGEEDSTPGRRSKAYSRQGADVRPMKGGHGINLVGTLMAATERGANIVEGVVDFRPTDLRGSLRRGREANLIVFV
VDTSGSMAARSRVRAVTGTITSMLNDAYQRRDKVAVIAVNGNKPTLVLNPTNSVEQAQQKLKDMPMGGRTPLAEGLLMAK
DLMARELRKEPGRRAILMVMTDGQDTSDAGEAGIATAAETVVKSRLSGNVVIDCEGRLKVRKERAGVLAEMLGGVCVRLR
DLNSEHIKMVINA
>Mature_253_residues
MRLASMGEEDSTPGRRSKAYSRQGADVRPMKGGHGINLVGTLMAATERGANIVEGVVDFRPTDLRGSLRRGREANLIVFV
VDTSGSMAARSRVRAVTGTITSMLNDAYQRRDKVAVIAVNGNKPTLVLNPTNSVEQAQQKLKDMPMGGRTPLAEGLLMAK
DLMARELRKEPGRRAILMVMTDGQDTSDAGEAGIATAAETVVKSRLSGNVVIDCEGRLKVRKERAGVLAEMLGGVCVRLR
DLNSEHIKMVINA

Specific function: Unknown

COG id: COG1240

COG function: function code H; Mg-chelatase subunit ChlD

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011704
- InterPro:   IPR012804
- InterPro:   IPR002035 [H]

Pfam domain/function: PF07728 AAA_5; PF00092 VWA [H]

EC number: 6.6.1.1

Molecular weight: Translated: 27227; Mature: 27227

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLASMGEEDSTPGRRSKAYSRQGADVRPMKGGHGINLVGTLMAATERGANIVEGVVDFR
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCC
PTDLRGSLRRGREANLIVFVVDTSGSMAARSRVRAVTGTITSMLNDAYQRRDKVAVIAVN
CCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
GNKPTLVLNPTNSVEQAQQKLKDMPMGGRTPLAEGLLMAKDLMARELRKEPGRRAILMVM
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
TDGQDTSDAGEAGIATAAETVVKSRLSGNVVIDCEGRLKVRKERAGVLAEMLGGVCVRLR
ECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHHHHHHEEEHC
DLNSEHIKMVINA
CCCCCEEEEEEEC
>Mature Secondary Structure
MRLASMGEEDSTPGRRSKAYSRQGADVRPMKGGHGINLVGTLMAATERGANIVEGVVDFR
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCC
PTDLRGSLRRGREANLIVFVVDTSGSMAARSRVRAVTGTITSMLNDAYQRRDKVAVIAVN
CCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
GNKPTLVLNPTNSVEQAQQKLKDMPMGGRTPLAEGLLMAKDLMARELRKEPGRRAILMVM
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
TDGQDTSDAGEAGIATAAETVVKSRLSGNVVIDCEGRLKVRKERAGVLAEMLGGVCVRLR
ECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHHHHHHEEEHC
DLNSEHIKMVINA
CCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; protoporphyrin IX; Mg2+; H2O

Specific reaction: ATP + protoporphyrin IX + Mg2+ + H2O = ADP + phosphate + Mg-protoporphyrin IX + 2 H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]