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The map label for this gene is gluD [H]

Identifier: 62390793

GI number: 62390793

Start: 2032364

End: 2033311

Strand: Direct

Name: gluD [H]

Synonym: cg2139

Alternate gene names: 62390793

Gene position: 2032364-2033311 (Clockwise)

Preceding gene: 62390792

Following gene: 62390798

Centisome position: 61.91

GC content: 53.16

Gene sequence:

>948_bases
ATGGCTAATACAGTTCGCGCAACAGTCCTCTACGATGCTCCTGGACCAAAGGGCCGTCGATTCAACCTCATAATCACCAT
TCTCACGGTGGTTCTGGGATTGGCGCTCCTCTTCTGGATTGGCTCCATGCTTTCAGGCAACGGCCAACTCGATGCCAACA
AATGGACTCCGTTCATCAATTCCCAAACCTGGACCACCTACATTCTTCCTGGTTTGTGGGGCACGCTGAAATCTGCCGTG
TTCTCGGTGATCTTGGCTCTGGTCATGGGTACCGCACTGGGTCTTGGCCGTATCTCTGAAATCAGGATTCTCCGCTGGTT
CTGCGCCGTCATCATCGAGACTTTCCGAGCCATTCCGGTTCTGATCCTCATGATTTTCGCCTACCAGATGTTCGCCCAGT
ACAACATCGTGCCGTCGAGCCAGCTCGCGTTCGCCGCCGTGGTATTCGGTCTGACCATGTACAACGGTTCTGTGATCGCA
GAGATTCTGCGTTCTGGTATCGCTTCCCTGCCTAAGGGGCAGAAGGAAGCAGCGATTGCGTTGGGTATGTCTTCTAGGCA
AACCACCTGGTCAATCTTGTTGCCTCAGGCCGTGGCTGCAATGCTCCCAGCGTTGATCTCTCAGATGGTTATTGCACTGA
AGGACTCCGCACTTGGTTACCAGATCGGCTACATTGAAGTGGTTCGTTCCGGTATTCAGTCCGCGTCTGTCAACCGCAAC
TACCTTGCAGCGCTGTTTGTTGTTGCGCTGATCATGATTGTTCTGAACTTCTCCCTCACCGCTCTGGCTTCTCGCATCGA
GCGCCAGTTGCGTGCAGGTAGGGCTCGTAAGAACATTGTTGCCAAGGTCCCTGAGCAGCCAGATCAAGGTCTGGAGACCA
AGGACAATGTCAATGTCGACTGGCAGGATCCTGATTATAAGGATCTGAAAACCCCTGGAGTTCAGTAA

Upstream 100 bases:

>100_bases
TTGTCGTGTTCGCGATCTTCGCCGTTGGCTTCATGATTCTGACCCTGCCTATGGGCCTTGGCTTGGGCAAACTCTCTGAG
CGTTTGGCGGTGAAGAAGTA

Downstream 100 bases:

>100_bases
CTCCCTTACCCCGGATGATTCCCATCCGGGGTTTAGTTTTTCAAATCCTCGATTCGCGCGTCTAGCGCTTCCCGCGCAAG
GTCCATGGACATTCCAGCCG

Product: glutamate permease

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MANTVRATVLYDAPGPKGRRFNLIITILTVVLGLALLFWIGSMLSGNGQLDANKWTPFINSQTWTTYILPGLWGTLKSAV
FSVILALVMGTALGLGRISEIRILRWFCAVIIETFRAIPVLILMIFAYQMFAQYNIVPSSQLAFAAVVFGLTMYNGSVIA
EILRSGIASLPKGQKEAAIALGMSSRQTTWSILLPQAVAAMLPALISQMVIALKDSALGYQIGYIEVVRSGIQSASVNRN
YLAALFVVALIMIVLNFSLTALASRIERQLRAGRARKNIVAKVPEQPDQGLETKDNVNVDWQDPDYKDLKTPGVQ

Sequences:

>Translated_315_residues
MANTVRATVLYDAPGPKGRRFNLIITILTVVLGLALLFWIGSMLSGNGQLDANKWTPFINSQTWTTYILPGLWGTLKSAV
FSVILALVMGTALGLGRISEIRILRWFCAVIIETFRAIPVLILMIFAYQMFAQYNIVPSSQLAFAAVVFGLTMYNGSVIA
EILRSGIASLPKGQKEAAIALGMSSRQTTWSILLPQAVAAMLPALISQMVIALKDSALGYQIGYIEVVRSGIQSASVNRN
YLAALFVVALIMIVLNFSLTALASRIERQLRAGRARKNIVAKVPEQPDQGLETKDNVNVDWQDPDYKDLKTPGVQ
>Mature_314_residues
ANTVRATVLYDAPGPKGRRFNLIITILTVVLGLALLFWIGSMLSGNGQLDANKWTPFINSQTWTTYILPGLWGTLKSAVF
SVILALVMGTALGLGRISEIRILRWFCAVIIETFRAIPVLILMIFAYQMFAQYNIVPSSQLAFAAVVFGLTMYNGSVIAE
ILRSGIASLPKGQKEAAIALGMSSRQTTWSILLPQAVAAMLPALISQMVIALKDSALGYQIGYIEVVRSGIQSASVNRNY
LAALFVVALIMIVLNFSLTALASRIERQLRAGRARKNIVAKVPEQPDQGLETKDNVNVDWQDPDYKDLKTPGVQ

Specific function: Part of the binding-protein-dependent transport system for glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=208, Percent_Identity=27.4038461538462, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082239, Length=193, Percent_Identity=28.4974093264249, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787030, Length=201, Percent_Identity=31.3432835820896, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788226, Length=216, Percent_Identity=29.6296296296296, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786874, Length=231, Percent_Identity=24.2424242424242, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI48994930, Length=84, Percent_Identity=40.4761904761905, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788645, Length=229, Percent_Identity=23.1441048034935, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34421; Mature: 34290

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTVRATVLYDAPGPKGRRFNLIITILTVVLGLALLFWIGSMLSGNGQLDANKWTPFIN
CCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
SQTWTTYILPGLWGTLKSAVFSVILALVMGTALGLGRISEIRILRWFCAVIIETFRAIPV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LILMIFAYQMFAQYNIVPSSQLAFAAVVFGLTMYNGSVIAEILRSGIASLPKGQKEAAIA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHE
LGMSSRQTTWSILLPQAVAAMLPALISQMVIALKDSALGYQIGYIEVVRSGIQSASVNRN
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCHH
YLAALFVVALIMIVLNFSLTALASRIERQLRAGRARKNIVAKVPEQPDQGLETKDNVNVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCC
WQDPDYKDLKTPGVQ
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
ANTVRATVLYDAPGPKGRRFNLIITILTVVLGLALLFWIGSMLSGNGQLDANKWTPFIN
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
SQTWTTYILPGLWGTLKSAVFSVILALVMGTALGLGRISEIRILRWFCAVIIETFRAIPV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LILMIFAYQMFAQYNIVPSSQLAFAAVVFGLTMYNGSVIAEILRSGIASLPKGQKEAAIA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHE
LGMSSRQTTWSILLPQAVAAMLPALISQMVIALKDSALGYQIGYIEVVRSGIQSASVNRN
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCHH
YLAALFVVALIMIVLNFSLTALASRIERQLRAGRARKNIVAKVPEQPDQGLETKDNVNVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCC
WQDPDYKDLKTPGVQ
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7868586; 12948626 [H]