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The map label for this gene is oxyR [H]

Identifier: 62390765

GI number: 62390765

Start: 1999225

End: 2000208

Strand: Direct

Name: oxyR [H]

Synonym: cg2109

Alternate gene names: 62390765

Gene position: 1999225-2000208 (Clockwise)

Preceding gene: 62390764

Following gene: 62390767

Centisome position: 60.9

GC content: 57.11

Gene sequence:

>984_bases
ATGAGCAATAAAGAGTACCGGCCCACACTCGCCCAGCTTCGCACCTTTGTCACCATCGCAGAATGCAAGCACTTTGGTAC
TGCTGCCACCAAGCTGTCCATTTCGCAGCCATCCCTCTCCCAGGCACTTGTCGCATTAGAAACAGGCCTGGGAGTTCAGC
TGATTGAACGCTCCACCCGCAAGGTCATTGTCACCCCAGCGGGCGAGAAGTTGCTGCCATTCGCCAAATCCACCCTTGAC
GCGGCGGAGTCTTTCCTCTCCCACGCCAAGGGCGCCAACGGTTCGCTCACTGGACCGTTGACCGTAGGCATCATCCCCAC
GGCGGCTCCTTACATTTTGCCGTCAATGCTGTCCATCGTGGATGAAGAATATCCAGATCTGGAACCTCACATCGTCGAGG
ACCAAACCAAGCATCTTCTCGCGTTGCTGCGCGACGGCGCCATCGACGTCGCCATGATGGCCCTGCCTTCTGAGGCACCA
GGCATGAAGGAAATCCCCCTCTACGACGAAGACTTTATCGTCGTTACAGCTAGCGATCACCCCTTCGCCGGCCGCCAAGA
CTTAGAACTATCCGCCTTAGAAGACCTCGATCTGCTGCTTCTCGACGACGGACACTGCCTCCACGACCAAATTGTGGACC
TGTGCCGCCGCGGAGACATCAACCCCATTAGCTCCACTACTGCTGTCACCCGCGCATCCAGCCTTACCACCGTCATGCAG
CTCGTCGTCGCCGGCCTTGGATCCACCTTGGTCCCAATCAGCGCAATCCCATGGGAATGCACCCGACCAGGACTGGCAAC
AGCCAACTTCAACTCTGATGTCACCGCAAACCGCCGCATTGGATTGGTGTACCGTTCCTCTTCTTCTCGCGCCGAAGAGT
TCGAACAGTTTGCACTCATTTTGCAGCGCGCTTTCCAAGAAGCCGTCGCGCTTGCTGCCTCAACTGGCATCACCTTGAAG
CAAAATGTCGCGGTAGCGCAGTAA

Upstream 100 bases:

>100_bases
TGCCTGATTTGAGCGGTTTTACCTATGGCGCTTTGGCGCCGTCAAACTGTCCCAGCGATTTCATTATTATTTTCGTGCAT
TCACCGTTATAGTTATAGGC

Downstream 100 bases:

>100_bases
GTTTTTCTAGAGGTTTTCCAGAGTCAGCTACAAGCAAAAAGCCCTTTCCATTGATGCACACCAACGTGAGATTCAAGGGA
AAGGGCTTTATTGATTGCAG

Product: hydrogen peroxide sensing regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSNKEYRPTLAQLRTFVTIAECKHFGTAATKLSISQPSLSQALVALETGLGVQLIERSTRKVIVTPAGEKLLPFAKSTLD
AAESFLSHAKGANGSLTGPLTVGIIPTAAPYILPSMLSIVDEEYPDLEPHIVEDQTKHLLALLRDGAIDVAMMALPSEAP
GMKEIPLYDEDFIVVTASDHPFAGRQDLELSALEDLDLLLLDDGHCLHDQIVDLCRRGDINPISSTTAVTRASSLTTVMQ
LVVAGLGSTLVPISAIPWECTRPGLATANFNSDVTANRRIGLVYRSSSSRAEEFEQFALILQRAFQEAVALAASTGITLK
QNVAVAQ

Sequences:

>Translated_327_residues
MSNKEYRPTLAQLRTFVTIAECKHFGTAATKLSISQPSLSQALVALETGLGVQLIERSTRKVIVTPAGEKLLPFAKSTLD
AAESFLSHAKGANGSLTGPLTVGIIPTAAPYILPSMLSIVDEEYPDLEPHIVEDQTKHLLALLRDGAIDVAMMALPSEAP
GMKEIPLYDEDFIVVTASDHPFAGRQDLELSALEDLDLLLLDDGHCLHDQIVDLCRRGDINPISSTTAVTRASSLTTVMQ
LVVAGLGSTLVPISAIPWECTRPGLATANFNSDVTANRRIGLVYRSSSSRAEEFEQFALILQRAFQEAVALAASTGITLK
QNVAVAQ
>Mature_326_residues
SNKEYRPTLAQLRTFVTIAECKHFGTAATKLSISQPSLSQALVALETGLGVQLIERSTRKVIVTPAGEKLLPFAKSTLDA
AESFLSHAKGANGSLTGPLTVGIIPTAAPYILPSMLSIVDEEYPDLEPHIVEDQTKHLLALLRDGAIDVAMMALPSEAPG
MKEIPLYDEDFIVVTASDHPFAGRQDLELSALEDLDLLLLDDGHCLHDQIVDLCRRGDINPISSTTAVTRASSLTTVMQL
VVAGLGSTLVPISAIPWECTRPGLATANFNSDVTANRRIGLVYRSSSSRAEEFEQFALILQRAFQEAVALAASTGITLKQ
NVAVAQ

Specific function: Required for the induction the katG gene for catalase. Involved in the response to hydrogen peroxide [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=286, Percent_Identity=37.4125874125874, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787879, Length=249, Percent_Identity=31.7269076305221, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI145693105, Length=252, Percent_Identity=29.3650793650794, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788887, Length=252, Percent_Identity=32.1428571428571, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI157672245, Length=241, Percent_Identity=29.045643153527, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI2367136, Length=247, Percent_Identity=27.1255060728745, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=25.3012048192771, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788297, Length=253, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87081904, Length=181, Percent_Identity=32.5966850828729, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787601, Length=187, Percent_Identity=25.1336898395722, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789506, Length=248, Percent_Identity=22.5806451612903, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=26.4822134387352, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790208, Length=245, Percent_Identity=27.3469387755102, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788626, Length=244, Percent_Identity=27.8688524590164, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788481, Length=175, Percent_Identity=25.7142857142857, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786713, Length=178, Percent_Identity=29.2134831460674, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787806, Length=170, Percent_Identity=26.4705882352941, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787589, Length=129, Percent_Identity=31.7829457364341, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35060; Mature: 34928

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKEYRPTLAQLRTFVTIAECKHFGTAATKLSISQPSLSQALVALETGLGVQLIERSTR
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHCCCCHHHEECCCC
KVIVTPAGEKLLPFAKSTLDAAESFLSHAKGANGSLTGPLTVGIIPTAAPYILPSMLSIV
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
DEEYPDLEPHIVEDQTKHLLALLRDGAIDVAMMALPSEAPGMKEIPLYDEDFIVVTASDH
HHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCC
PFAGRQDLELSALEDLDLLLLDDGHCLHDQIVDLCRRGDINPISSTTAVTRASSLTTVMQ
CCCCCCCCCHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LVVAGLGSTLVPISAIPWECTRPGLATANFNSDVTANRRIGLVYRSSSSRAEEFEQFALI
HHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHH
LQRAFQEAVALAASTGITLKQNVAVAQ
HHHHHHHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure 
SNKEYRPTLAQLRTFVTIAECKHFGTAATKLSISQPSLSQALVALETGLGVQLIERSTR
CCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHCCCCHHHEECCCC
KVIVTPAGEKLLPFAKSTLDAAESFLSHAKGANGSLTGPLTVGIIPTAAPYILPSMLSIV
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
DEEYPDLEPHIVEDQTKHLLALLRDGAIDVAMMALPSEAPGMKEIPLYDEDFIVVTASDH
HHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCC
PFAGRQDLELSALEDLDLLLLDDGHCLHDQIVDLCRRGDINPISSTTAVTRASSLTTVMQ
CCCCCCCCCHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LVVAGLGSTLVPISAIPWECTRPGLATANFNSDVTANRRIGLVYRSSSSRAEEFEQFALI
HHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHH
LQRAFQEAVALAASTGITLKQNVAVAQ
HHHHHHHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8006590; 11234002 [H]