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The map label for this gene is clpC [H]

Identifier: 62390668

GI number: 62390668

Start: 1898843

End: 1900630

Strand: Reverse

Name: clpC [H]

Synonym: cg2009

Alternate gene names: 62390668

Gene position: 1900630-1898843 (Counterclockwise)

Preceding gene: 62390669

Following gene: 62390667

Centisome position: 57.9

GC content: 49.44

Gene sequence:

>1788_bases
ATGACCCAGGTTGTGGCGGGTACGTTGGTGGGAGAGTCGATTAATCGTGAGATTGATGAAGACAAGTACCCTTATTTGAG
CTCGTATGCAGCGCCTGTTGCTGTACCGGTGCGTGAGATTATTGGGCGCGAAGAAGAAGTCAATAAGATTATGGCCGCGC
TGATGCGTCCAGAGATTTCTAATGTCATGCTTGTGGGTCCTGCTGGTTCGGGTAAAACTACGTTGGTACAGCAAGCACTG
GTGAAAGATCCAGAGCGTAACTACATCGAGGTCGATGTAGCGAAAATGGTTGCGGATTTGAGCACCCCGGCGCAAATGGC
TGCGCGTATTAAAGGTGTGTTTGAGGACGCCATTGCCTATCGCAAGCACGAAGGTCATGAATTGGTGCTGTTCGTTGATG
AGTTTCACCAAATTGTGCAGCTGTCTAATGCTGCGGTAGAGGCAATCAAGCCGATTTTGGCGATGTCTGGTGTCCTTGGT
GTGCGCGTTATCGCTGCGACAACTCTCGAAGAATTTCACGAACACATCAGGCCGAACCAAGCATTGACGGAGCGTTTGCA
GGAAATTCGACTAACGCCGACCGATCAGAAGACCACTGTGGCGATTTTGCGTGGTATGGCAGATCGTTATGGCGTAAGTG
ATCAGTTCTATGACGACCACGTTTTTGAGCAGATTTACTCCACCACTGAGCGTTTTATGCCGAGTTCTGTCCAGCCTCGT
AAATCCATTCGTGTCCTTGATGCGATGGTTGGTTGGCATCGACTTTCCGGCAAGCCGATGGATATGGATCTGCTCGGTGA
TGTGCTCCACGATGCTATTGGTGTCGATATTGCATTCAAGGTCGATGGTACGAGCATTAAAGACAAGCTTGATGAGAAGG
TAATGGCGCAAAGTCTTGCCACCACTGTGGTAGCACGTCGTTTGCAGCTGGTGGTGGCGGATCTTCATGATAAATCACGG
CCACTGTCGAACTTCTTGTTCACCGGGCCTACTGGTGTCGGTAAAACAGAGCTGGTCAAGCAACTAGCACGGGTGCTCTT
TGGTGATGACACTGGGCGATTGATTCGTTTTGACATGTCAGAGTTCGCCTTAGAATCAAGTCTTGACCTTTTCAGGTCTG
AGCTCACTCGTCGTGTCGCTGACCAGGGTAACGCTATTGTCCTGCTCGATGAGGTTGAGAAAGCTGATCGAGCTATTGCG
CGGTTGTTACTGCAGGTACTTGATGATGGCCGACTATCTGACGATTACAACCGTGAGGTGAGTTTTCTTAATACCTATAT
CGTCATGACAACTAACGCTGGTTCTGAGATTTTCGAGACAATTTCGAACTATGCCACTGATGACACGGGCGATGGTCGGG
CGATCAAAGACTTTGTGAAAAACATTCACACGTCGATCAAGAATAAGGGTTTTCCACCTGAGCTTCTTGGTCGTGTAGAT
GAAATTGTGCCTTTTCAACCGCTGTCGGAGACGACACAGGACAGGATTATTAGCAAGAAGCTGCAGGATGTGGCTACTGA
GGTCTATGAACGCCACGGCGTGAAACTGCACTGTTCACAAAAGGTTATGGAGTTTCTGCTTGTGGATCAGGTGGAGGAAA
GTGCTGAATCTGGTGGTGCCCGTGGTGCGGTGCGGTCTTTGCAGCGGGAAGTGGTCACTGAAGTGGCGACCTTTATTAAT
ACCTACCCAGAAGTGCGTGACATTTACGTTGATGTCGATGGTCAGATGCGTAATAAGACTAACCGTGTGTCTACGGCCCG
TGTGGTGATAAAGCGTGTCGAAGGTTAA

Upstream 100 bases:

>100_bases
ACAATATTTACGGGGATAATCTGCATTAACAAATTAGTTAATAAAGTGTAGTATTTAATTAATTATTAAATTCAATTAAC
TTTTTTGTAAAGGTGGGAAG

Downstream 100 bases:

>100_bases
TTACTCTGGGGTCGCTTAAATAAGTTTTAAACATAAAGAAACTCAATATTAAAGTCGCGTAATTAGTGTTATATTAATTA
CGCGACTTTAATAGTTTTCG

Product: Clp family ATP-binding protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MTQVVAGTLVGESINREIDEDKYPYLSSYAAPVAVPVREIIGREEEVNKIMAALMRPEISNVMLVGPAGSGKTTLVQQAL
VKDPERNYIEVDVAKMVADLSTPAQMAARIKGVFEDAIAYRKHEGHELVLFVDEFHQIVQLSNAAVEAIKPILAMSGVLG
VRVIAATTLEEFHEHIRPNQALTERLQEIRLTPTDQKTTVAILRGMADRYGVSDQFYDDHVFEQIYSTTERFMPSSVQPR
KSIRVLDAMVGWHRLSGKPMDMDLLGDVLHDAIGVDIAFKVDGTSIKDKLDEKVMAQSLATTVVARRLQLVVADLHDKSR
PLSNFLFTGPTGVGKTELVKQLARVLFGDDTGRLIRFDMSEFALESSLDLFRSELTRRVADQGNAIVLLDEVEKADRAIA
RLLLQVLDDGRLSDDYNREVSFLNTYIVMTTNAGSEIFETISNYATDDTGDGRAIKDFVKNIHTSIKNKGFPPELLGRVD
EIVPFQPLSETTQDRIISKKLQDVATEVYERHGVKLHCSQKVMEFLLVDQVEESAESGGARGAVRSLQREVVTEVATFIN
TYPEVRDIYVDVDGQMRNKTNRVSTARVVIKRVEG

Sequences:

>Translated_595_residues
MTQVVAGTLVGESINREIDEDKYPYLSSYAAPVAVPVREIIGREEEVNKIMAALMRPEISNVMLVGPAGSGKTTLVQQAL
VKDPERNYIEVDVAKMVADLSTPAQMAARIKGVFEDAIAYRKHEGHELVLFVDEFHQIVQLSNAAVEAIKPILAMSGVLG
VRVIAATTLEEFHEHIRPNQALTERLQEIRLTPTDQKTTVAILRGMADRYGVSDQFYDDHVFEQIYSTTERFMPSSVQPR
KSIRVLDAMVGWHRLSGKPMDMDLLGDVLHDAIGVDIAFKVDGTSIKDKLDEKVMAQSLATTVVARRLQLVVADLHDKSR
PLSNFLFTGPTGVGKTELVKQLARVLFGDDTGRLIRFDMSEFALESSLDLFRSELTRRVADQGNAIVLLDEVEKADRAIA
RLLLQVLDDGRLSDDYNREVSFLNTYIVMTTNAGSEIFETISNYATDDTGDGRAIKDFVKNIHTSIKNKGFPPELLGRVD
EIVPFQPLSETTQDRIISKKLQDVATEVYERHGVKLHCSQKVMEFLLVDQVEESAESGGARGAVRSLQREVVTEVATFIN
TYPEVRDIYVDVDGQMRNKTNRVSTARVVIKRVEG
>Mature_594_residues
TQVVAGTLVGESINREIDEDKYPYLSSYAAPVAVPVREIIGREEEVNKIMAALMRPEISNVMLVGPAGSGKTTLVQQALV
KDPERNYIEVDVAKMVADLSTPAQMAARIKGVFEDAIAYRKHEGHELVLFVDEFHQIVQLSNAAVEAIKPILAMSGVLGV
RVIAATTLEEFHEHIRPNQALTERLQEIRLTPTDQKTTVAILRGMADRYGVSDQFYDDHVFEQIYSTTERFMPSSVQPRK
SIRVLDAMVGWHRLSGKPMDMDLLGDVLHDAIGVDIAFKVDGTSIKDKLDEKVMAQSLATTVVARRLQLVVADLHDKSRP
LSNFLFTGPTGVGKTELVKQLARVLFGDDTGRLIRFDMSEFALESSLDLFRSELTRRVADQGNAIVLLDEVEKADRAIAR
LLLQVLDDGRLSDDYNREVSFLNTYIVMTTNAGSEIFETISNYATDDTGDGRAIKDFVKNIHTSIKNKGFPPELLGRVDE
IVPFQPLSETTQDRIISKKLQDVATEVYERHGVKLHCSQKVMEFLLVDQVEESAESGGARGAVRSLQREVVTEVATFINT
YPEVRDIYVDVDGQMRNKTNRVSTARVVIKRVEG

Specific function: Required for growth at high temperatures, probably by acting as a chaperone during heat shock and targeting heat- denatured proteins for degradation by ClpP [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=303, Percent_Identity=29.042904290429, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1787109, Length=549, Percent_Identity=28.9617486338798, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1788943, Length=291, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320464, Length=323, Percent_Identity=33.1269349845201, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323002, Length=289, Percent_Identity=29.0657439446367, Blast_Score=104, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 66337; Mature: 66205

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVVAGTLVGESINREIDEDKYPYLSSYAAPVAVPVREIIGREEEVNKIMAALMRPEIS
CCCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCC
NVMLVGPAGSGKTTLVQQALVKDPERNYIEVDVAKMVADLSTPAQMAARIKGVFEDAIAY
CEEEEECCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RKHEGHELVLFVDEFHQIVQLSNAAVEAIKPILAMSGVLGVRVIAATTLEEFHEHIRPNQ
HCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ALTERLQEIRLTPTDQKTTVAILRGMADRYGVSDQFYDDHVFEQIYSTTERFMPSSVQPR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
KSIRVLDAMVGWHRLSGKPMDMDLLGDVLHDAIGVDIAFKVDGTSIKDKLDEKVMAQSLA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHH
TTVVARRLQLVVADLHDKSRPLSNFLFTGPTGVGKTELVKQLARVLFGDDTGRLIRFDMS
HHHHHHHHHHHHHHHHCCCCCHHHCEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHH
EFALESSLDLFRSELTRRVADQGNAIVLLDEVEKADRAIARLLLQVLDDGRLSDDYNREV
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
SFLNTYIVMTTNAGSEIFETISNYATDDTGDGRAIKDFVKNIHTSIKNKGFPPELLGRVD
HEEEEEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
EIVPFQPLSETTQDRIISKKLQDVATEVYERHGVKLHCSQKVMEFLLVDQVEESAESGGA
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCC
RGAVRSLQREVVTEVATFINTYPEVRDIYVDVDGQMRNKTNRVSTARVVIKRVEG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQVVAGTLVGESINREIDEDKYPYLSSYAAPVAVPVREIIGREEEVNKIMAALMRPEIS
CCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCC
NVMLVGPAGSGKTTLVQQALVKDPERNYIEVDVAKMVADLSTPAQMAARIKGVFEDAIAY
CEEEEECCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RKHEGHELVLFVDEFHQIVQLSNAAVEAIKPILAMSGVLGVRVIAATTLEEFHEHIRPNQ
HCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ALTERLQEIRLTPTDQKTTVAILRGMADRYGVSDQFYDDHVFEQIYSTTERFMPSSVQPR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
KSIRVLDAMVGWHRLSGKPMDMDLLGDVLHDAIGVDIAFKVDGTSIKDKLDEKVMAQSLA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHH
TTVVARRLQLVVADLHDKSRPLSNFLFTGPTGVGKTELVKQLARVLFGDDTGRLIRFDMS
HHHHHHHHHHHHHHHHCCCCCHHHCEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHH
EFALESSLDLFRSELTRRVADQGNAIVLLDEVEKADRAIARLLLQVLDDGRLSDDYNREV
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
SFLNTYIVMTTNAGSEIFETISNYATDDTGDGRAIKDFVKNIHTSIKNKGFPPELLGRVD
HEEEEEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
EIVPFQPLSETTQDRIISKKLQDVATEVYERHGVKLHCSQKVMEFLLVDQVEESAESGGA
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCC
RGAVRSLQREVVTEVATFINTYPEVRDIYVDVDGQMRNKTNRVSTARVVIKRVEG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA