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The map label for this gene is dgoR [H]

Identifier: 62390600

GI number: 62390600

Start: 1815252

End: 1815992

Strand: Direct

Name: dgoR [H]

Synonym: cg1935

Alternate gene names: 62390600

Gene position: 1815252-1815992 (Clockwise)

Preceding gene: 62390599

Following gene: 62390601

Centisome position: 55.3

GC content: 51.69

Gene sequence:

>741_bases
ATGTCCGCAGCTTTACCTCACACAGCAGCAGATCCCGTACACACCACCCCAGCGAAACCGCTGCTCGATCATGTCTTAGA
TTCACTAGGACGCAGCATCATCAGTGGTGAAATGGAAGCCGGTAGCACATTCAAACTGCAAGACATCGGTGAAAAATTCG
GTATCTCCCGCACCGTCGCCAGAGAAGCCATGCGTGCCTTAGAGCAACTTGGGTTGGTGGCCTCATCGAGACGAATTGGT
ATTACAGTGCTCTCGCACGAGCACTGGGCTGTCTTTGACAAAGCCATTATTCGCTGGCGCCTCGAAGATGAGCGTCAACG
TGAACAGCAACTGCAGTCACTCACCGAACTTCGTATTGCCATTGAACCAATTGCTGCACGCAGTGTTGCCCTTCATGCAT
CGAGCGCAGAGATTGCTATCATCGGTGATCTTGCTGCACGAATGCGTAACCTCGGTGAAGCTGGTCGTGGCGCATCACAA
GAATTCCTAGACGCAGATGTGAAATTTCATGAGCTTATTTTGCAGTATTGCCATAATGAGATGTTCGCTGCCATGGCACC
ACCCATAAAAGCTGTACTAGTCGGGCGCACCACACTTGGCCTTCAACCCGATCGACCTGCCGAAGAAGTCTTGGACAATC
ATGATGCTCTCGCACACGCACTAAGTGTTCGTAATGCAGACCTCGCCGAAAAAGCATCCAGGAGCATTCTGAATGAGGTG
CGCGACGCACTGACCTCGTAA

Upstream 100 bases:

>100_bases
TTCGCCACACTCCCAATATCTACCAAAAATGGTGATCTATTATACATAATGGAATTACCAAAGCTTCATATCACTTTTCC
ACAGCCTGAAAGAACATACT

Downstream 100 bases:

>100_bases
TTGCCACTAAACGAGTCACTACACAATTACATCGCTCATTGTTACTTAATTACCCTTTAATAGTCTTTTACAAGGCTGTT
AAAGGGTAATTTTTTATTAG

Product: GntR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSAALPHTAADPVHTTPAKPLLDHVLDSLGRSIISGEMEAGSTFKLQDIGEKFGISRTVAREAMRALEQLGLVASSRRIG
ITVLSHEHWAVFDKAIIRWRLEDERQREQQLQSLTELRIAIEPIAARSVALHASSAEIAIIGDLAARMRNLGEAGRGASQ
EFLDADVKFHELILQYCHNEMFAAMAPPIKAVLVGRTTLGLQPDRPAEEVLDNHDALAHALSVRNADLAEKASRSILNEV
RDALTS

Sequences:

>Translated_246_residues
MSAALPHTAADPVHTTPAKPLLDHVLDSLGRSIISGEMEAGSTFKLQDIGEKFGISRTVAREAMRALEQLGLVASSRRIG
ITVLSHEHWAVFDKAIIRWRLEDERQREQQLQSLTELRIAIEPIAARSVALHASSAEIAIIGDLAARMRNLGEAGRGASQ
EFLDADVKFHELILQYCHNEMFAAMAPPIKAVLVGRTTLGLQPDRPAEEVLDNHDALAHALSVRNADLAEKASRSILNEV
RDALTS
>Mature_245_residues
SAALPHTAADPVHTTPAKPLLDHVLDSLGRSIISGEMEAGSTFKLQDIGEKFGISRTVAREAMRALEQLGLVASSRRIGI
TVLSHEHWAVFDKAIIRWRLEDERQREQQLQSLTELRIAIEPIAARSVALHASSAEIAIIGDLAARMRNLGEAGRGASQE
FLDADVKFHELILQYCHNEMFAAMAPPIKAVLVGRTTLGLQPDRPAEEVLDNHDALAHALSVRNADLAEKASRSILNEVR
DALTS

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=219, Percent_Identity=27.3972602739726, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI48994961, Length=222, Percent_Identity=28.8288288288288, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26884; Mature: 26753

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAALPHTAADPVHTTPAKPLLDHVLDSLGRSIISGEMEAGSTFKLQDIGEKFGISRTVA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCCHHHHH
REAMRALEQLGLVASSRRIGITVLSHEHWAVFDKAIIRWRLEDERQREQQLQSLTELRIA
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
IEPIAARSVALHASSAEIAIIGDLAARMRNLGEAGRGASQEFLDADVKFHELILQYCHNE
HHHHHHHHHEEECCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
MFAAMAPPIKAVLVGRTTLGLQPDRPAEEVLDNHDALAHALSVRNADLAEKASRSILNEV
HHHHHCCCHHHHEECCHHCCCCCCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
RDALTS
HHHHCC
>Mature Secondary Structure 
SAALPHTAADPVHTTPAKPLLDHVLDSLGRSIISGEMEAGSTFKLQDIGEKFGISRTVA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCCHHHHH
REAMRALEQLGLVASSRRIGITVLSHEHWAVFDKAIIRWRLEDERQREQQLQSLTELRIA
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
IEPIAARSVALHASSAEIAIIGDLAARMRNLGEAGRGASQEFLDADVKFHELILQYCHNE
HHHHHHHHHEEECCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
MFAAMAPPIKAVLVGRTTLGLQPDRPAEEVLDNHDALAHALSVRNADLAEKASRSILNEV
HHHHHCCCHHHHEECCHHCCCCCCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
RDALTS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]