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The map label for this gene is pyrR [H]

Identifier: 62390496

GI number: 62390496

Start: 1712817

End: 1713452

Strand: Reverse

Name: pyrR [H]

Synonym: cg1817

Alternate gene names: 62390496

Gene position: 1713452-1712817 (Counterclockwise)

Preceding gene: 62390501

Following gene: 62390495

Centisome position: 52.2

GC content: 53.93

Gene sequence:

>636_bases
TTGCAAAATTGGACATCCTTTAACGGACCGCACAGAGAGGCGGGGAAGGAGGTCACGATGAGCGAACGTAATAGTGCTGT
ACTAGAACTCCTTAATGAGGACGACGTCAGCCGTACCATCGCACGCATCGCGCACCAGATTATTGAGAAAACCGCGCTTG
ATTCCAAAGACGCGGATCGGGTCATGTTGTTAGGTATTCCCTCAGGTGGAGTCCCATTGGCCCGTAGGCTCGCTGAAAAG
ATCGAAGAATTTTCCGGCGTTTCGGTAGATACCGGCGCTGTTGATATCACCTTGTACAGGGATGATCTTCGAAACAAACC
ACACCGCGCACTGCAGCCCACCTCTATTCCAGCAGGTGGTATCGATAACACCACCGTGATTTTGGTGGATGATGTGCTGT
TTTCCGGTCGTACCATCCGCGCTGCACTTGATGCTTTGCGCGACGTTGGACGCCCCAACTACATCCAGTTAGCTGTGTTG
GTTGACCGCGGTCATCGCCAGCTGCCCATTCGCGCTGACTATGTGGGCAAAAATCTCCCCACCGCACGCGCGGAAGACGT
TTCCGTCATGCTTACAGAAATCGACGGCCGCGATGCAGTCACGCTCACCCGAGAAGACTCTGAAGGGGATTCCTAG

Upstream 100 bases:

>100_bases
GGAGCACTACCTTAAGATCATAGTCAGCATCTTGGGGTGAATGTGACACGGTACGCTATAGTGTCAGACAACAACCAGGA
AACTGGTCGTTGCAGAGTTT

Downstream 100 bases:

>100_bases
ATGAAGCACCTCCTATCCATTAGCGATCTTTCCAAAGATGAGATTGTTGGATTGCTGGATGAAGCGGATCGCTTTAAGGA
GGTGCTCGAAGGACGTGAAG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MQNWTSFNGPHREAGKEVTMSERNSAVLELLNEDDVSRTIARIAHQIIEKTALDSKDADRVMLLGIPSGGVPLARRLAEK
IEEFSGVSVDTGAVDITLYRDDLRNKPHRALQPTSIPAGGIDNTTVILVDDVLFSGRTIRAALDALRDVGRPNYIQLAVL
VDRGHRQLPIRADYVGKNLPTARAEDVSVMLTEIDGRDAVTLTREDSEGDS

Sequences:

>Translated_211_residues
MQNWTSFNGPHREAGKEVTMSERNSAVLELLNEDDVSRTIARIAHQIIEKTALDSKDADRVMLLGIPSGGVPLARRLAEK
IEEFSGVSVDTGAVDITLYRDDLRNKPHRALQPTSIPAGGIDNTTVILVDDVLFSGRTIRAALDALRDVGRPNYIQLAVL
VDRGHRQLPIRADYVGKNLPTARAEDVSVMLTEIDGRDAVTLTREDSEGDS
>Mature_211_residues
MQNWTSFNGPHREAGKEVTMSERNSAVLELLNEDDVSRTIARIAHQIIEKTALDSKDADRVMLLGIPSGGVPLARRLAEK
IEEFSGVSVDTGAVDITLYRDDLRNKPHRALQPTSIPAGGIDNTTVILVDDVLFSGRTIRAALDALRDVGRPNYIQLAVL
VDRGHRQLPIRADYVGKNLPTARAEDVSVMLTEIDGRDAVTLTREDSEGDS

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 23123; Mature: 23123

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNWTSFNGPHREAGKEVTMSERNSAVLELLNEDDVSRTIARIAHQIIEKTALDSKDADR
CCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
VMLLGIPSGGVPLARRLAEKIEEFSGVSVDTGAVDITLYRDDLRNKPHRALQPTSIPAGG
EEEEEECCCCHHHHHHHHHHHHHHCCCCEECCEEEEEEEHHHHCCCCCCCCCCCCCCCCC
IDNTTVILVDDVLFSGRTIRAALDALRDVGRPNYIQLAVLVDRGHRQLPIRADYVGKNLP
CCCCEEEEEECHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCC
TARAEDVSVMLTEIDGRDAVTLTREDSEGDS
CCCCCCEEEEEEECCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MQNWTSFNGPHREAGKEVTMSERNSAVLELLNEDDVSRTIARIAHQIIEKTALDSKDADR
CCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
VMLLGIPSGGVPLARRLAEKIEEFSGVSVDTGAVDITLYRDDLRNKPHRALQPTSIPAGG
EEEEEECCCCHHHHHHHHHHHHHHCCCCEECCEEEEEEEHHHHCCCCCCCCCCCCCCCCC
IDNTTVILVDDVLFSGRTIRAALDALRDVGRPNYIQLAVLVDRGHRQLPIRADYVGKNLP
CCCCEEEEEECHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCC
TARAEDVSVMLTEIDGRDAVTLTREDSEGDS
CCCCCCEEEEEEECCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA