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The map label for this gene is sseA2 [H]

Identifier: 62390308

GI number: 62390308

Start: 1503177

End: 1504046

Strand: Direct

Name: sseA2 [H]

Synonym: cg1613

Alternate gene names: 62390308

Gene position: 1503177-1504046 (Clockwise)

Preceding gene: 62390306

Following gene: 62390309

Centisome position: 45.79

GC content: 53.22

Gene sequence:

>870_bases
ATGACTTCTCTTAAAGTAACTTCGTCCGCAGATGCAACCAATAACAATGATGCCCATTTTCCTGAAGGTCCAGTGGTAAC
CGTTGACTGGTTGTCACACAACCTTGACCGGGATGATGTCATCGTGTTGTGTGCCACAATGGAGGATGATGAAATTGCAC
GTCAAGCGGGAATTCCGGGGGCATTTCTCGCTGACTTGGAAGGAGATTTCTCAGATCCACATTCCGAGCTTCCACACACC
GCGCCACCAAATTTGGTGGGTTTGCTAGAAAGCTACGGCATTAGCACCGATTCCACGGTGGTTGTTTATGATCTGCACGG
CCTCATGGTTGCACCGCGGGTGTGGTGGCTTCTCCGTGTTGCTGGATTAAGCAGCATTGGCGTGCTTGATGGCGGATTGC
CAGCCTGGGTTGATGCTGGCCTTCCAACGGAACCGCTGTCGCTACCTACAAGTGGTGGAAGGATCAGCGCAGAACCACAG
CCAGATTTACTCGTTGGTGCCTCCGGCGTTGAACGGGCGATCGCGCGCTCAAGCAAGGCAGTGATTGATGCTCGTAATGC
GAGCCGATTCGCTGGCGTTGAAGAAGAGCCCCGTCCAGGCCTTCGAAAAGGGTCGATCCCTGGAAGCGTCAACATTCCCT
TCACTGACATTTCTGATGAGCATGGTTTTGTCCGGCCAGCAGAAGAACTGAAGGAATTGATCTTCAGCCGCACAAATGGA
GCGCAGTCGTTGGTCTTTAGCTGTGGCTCCGGAGTCACGGCATGTGTTGATGCCTACGCTGCAGTTATCGCAGGTTATGA
CGACGTTGTAGTGTATGAAGGCTCTTGGGCGGAGTGGGGCAACCCGGCAAACCAAAAGCCGATTGCTTAA

Upstream 100 bases:

>100_bases
GGTGGGAGAGTGCTACTATCTGCGGTTTTGTGAATTAAATGCTGTGAACTACCGCGAACTCCTCCCATTCAAGTGGTGTT
AAGCACTAAGATGGCAGGTT

Downstream 100 bases:

>100_bases
CGCCCGCTATGATAACCACTCATGAATGATTTCGATCCAGCATTGATTTCCGCGATGAGCCTTATCCCTCAGACGAGGTC
TCGGATGGAATCAATCTTGT

Product: rhodanese-related sulfurtransferase

Products: NA

Alternate protein names: MST; Rhodanese-like protein [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTSLKVTSSADATNNNDAHFPEGPVVTVDWLSHNLDRDDVIVLCATMEDDEIARQAGIPGAFLADLEGDFSDPHSELPHT
APPNLVGLLESYGISTDSTVVVYDLHGLMVAPRVWWLLRVAGLSSIGVLDGGLPAWVDAGLPTEPLSLPTSGGRISAEPQ
PDLLVGASGVERAIARSSKAVIDARNASRFAGVEEEPRPGLRKGSIPGSVNIPFTDISDEHGFVRPAEELKELIFSRTNG
AQSLVFSCGSGVTACVDAYAAVIAGYDDVVVYEGSWAEWGNPANQKPIA

Sequences:

>Translated_289_residues
MTSLKVTSSADATNNNDAHFPEGPVVTVDWLSHNLDRDDVIVLCATMEDDEIARQAGIPGAFLADLEGDFSDPHSELPHT
APPNLVGLLESYGISTDSTVVVYDLHGLMVAPRVWWLLRVAGLSSIGVLDGGLPAWVDAGLPTEPLSLPTSGGRISAEPQ
PDLLVGASGVERAIARSSKAVIDARNASRFAGVEEEPRPGLRKGSIPGSVNIPFTDISDEHGFVRPAEELKELIFSRTNG
AQSLVFSCGSGVTACVDAYAAVIAGYDDVVVYEGSWAEWGNPANQKPIA
>Mature_288_residues
TSLKVTSSADATNNNDAHFPEGPVVTVDWLSHNLDRDDVIVLCATMEDDEIARQAGIPGAFLADLEGDFSDPHSELPHTA
PPNLVGLLESYGISTDSTVVVYDLHGLMVAPRVWWLLRVAGLSSIGVLDGGLPAWVDAGLPTEPLSLPTSGGRISAEPQP
DLLVGASGVERAIARSSKAVIDARNASRFAGVEEEPRPGLRKGSIPGSVNIPFTDISDEHGFVRPAEELKELIFSRTNGA
QSLVFSCGSGVTACVDAYAAVIAGYDDVVVYEGSWAEWGNPANQKPIA

Specific function: Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity [H]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI194473668, Length=227, Percent_Identity=36.1233480176211, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI61835204, Length=227, Percent_Identity=36.1233480176211, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI194473681, Length=227, Percent_Identity=36.1233480176211, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI17402865, Length=259, Percent_Identity=34.7490347490347, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI87082121, Length=270, Percent_Identity=35.5555555555556, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI87081967, Length=250, Percent_Identity=28.4, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561888, Length=289, Percent_Identity=23.8754325259516, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71997283, Length=294, Percent_Identity=23.1292517006803, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.2 [H]

Molecular weight: Translated: 30499; Mature: 30368

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS00683 RHODANESE_2 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLKVTSSADATNNNDAHFPEGPVVTVDWLSHNLDRDDVIVLCATMEDDEIARQAGIPG
CCCEEECCCCCCCCCCCCCCCCCCEEEEEHHCCCCCCCCEEEEEEECCHHHHHHHHCCCC
AFLADLEGDFSDPHSELPHTAPPNLVGLLESYGISTDSTVVVYDLHGLMVAPRVWWLLRV
EEEECCCCCCCCCHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHH
AGLSSIGVLDGGLPAWVDAGLPTEPLSLPTSGGRISAEPQPDLLVGASGVERAIARSSKA
HCCCCCCEECCCCHHHCCCCCCCCCCCCCCCCCEECCCCCCCEEEECHHHHHHHHHCCHH
VIDARNASRFAGVEEEPRPGLRKGSIPGSVNIPFTDISDEHGFVRPAEELKELIFSRTNG
EEECCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
AQSLVFSCGSGVTACVDAYAAVIAGYDDVVVYEGSWAEWGNPANQKPIA
HHHHEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCHHCCCCCCCCCCC
>Mature Secondary Structure 
TSLKVTSSADATNNNDAHFPEGPVVTVDWLSHNLDRDDVIVLCATMEDDEIARQAGIPG
CCEEECCCCCCCCCCCCCCCCCCEEEEEHHCCCCCCCCEEEEEEECCHHHHHHHHCCCC
AFLADLEGDFSDPHSELPHTAPPNLVGLLESYGISTDSTVVVYDLHGLMVAPRVWWLLRV
EEEECCCCCCCCCHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHH
AGLSSIGVLDGGLPAWVDAGLPTEPLSLPTSGGRISAEPQPDLLVGASGVERAIARSSKA
HCCCCCCEECCCCHHHCCCCCCCCCCCCCCCCCEECCCCCCCEEEECHHHHHHHHHCCHH
VIDARNASRFAGVEEEPRPGLRKGSIPGSVNIPFTDISDEHGFVRPAEELKELIFSRTNG
EEECCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
AQSLVFSCGSGVTACVDAYAAVIAGYDDVVVYEGSWAEWGNPANQKPIA
HHHHEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]