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The map label for this gene is mdmB [H]

Identifier: 62390277

GI number: 62390277

Start: 1463601

End: 1464986

Strand: Direct

Name: mdmB [H]

Synonym: cg1578

Alternate gene names: 62390277

Gene position: 1463601-1464986 (Clockwise)

Preceding gene: 62390276

Following gene: 62390278

Centisome position: 44.59

GC content: 51.3

Gene sequence:

>1386_bases
ATGACGTCGAAAAGCATTAGCGGCAAGCGCCCGAATCTGCCGTCGCTCACTGGAGCGCGGTGGCTCGCGGCGCTCGCTGT
TTATTTTTTGCATGCGTTGGTGTTTTTGTCGGTGTATCCGTTCCAGCAGTCGGAACTGTTTGCCACAATCCATAAATTTG
TCCCCATGCAGCTGGGTTCAGCTGGTGTAACCTTCTTCTTTATCTTGTCCGGATTTTTGATCTATTGGTCAAATAGCCAG
CTCAAGGGCATGAAGAATGTGCTGTATTACTGCAAGCGCCGCATCACCAAGATTTATCCCATGCACTTGATTGCGTTGGC
GATGTTTATTGTGGCGTCGGCGAAGTTCACGACTACAGGCATTACCTGGGTGCTGGATTTTGCGCGAGTAGAGCTGTGGC
TGCCGAATGCGCTGCTCATCCACACGTGGAATCCTGATTGGGTGACGCTGGGTGGATTGAATGTACCATCGTGGTCGCTG
GGCGCGGAAATGCTGTTCTACCTGACGTTCCCGCTGTTTATTCCGTTAGTGCGCAAAGTGAAGGGCGTGGGCAACTGGTG
GGCATTTGGCATCACCTTTGCCGTGAGCCTGGCGCTGATTACAGTGATTCACTTTTATGCGGACGGACCAAAGGGGATTG
AGAACTTCTTTGTTCCTCGCCTGTGGGACACCAATGTGTCACCGGTCGCGGAAGTTCACGCCGATCCAGTGTGGTTTATG
CAGGAAGAAATTCCCGTGCTGGAATCTTACTGGCTGTCTTACTACTTCCCGCTGACCAGACTCATCGAGTTCTACCTCGG
TGTGTTTGGCGCGAAGCTGGTTGCTGAAGGCATGTTTAAAAACACCAACATCACCATCCCGCTGATCGCACTGGCTGTTT
CTTTTGTTGCTACTTGGTTTGTGCCACTGGCATTCAAGATGTCTGTCATCATGTCCCTGCCAATGGCTTTTGTTGTGGCA
ACGCTTGCGGTGAGAGACATTGAAGGCAAGAGTGGGGAAATCGCCTCGCCTCGCGCAGTTTTGTTGGGTAATATTTCCTT
TGCCTTCTACATGGTGCAATTCCCCGTCATGGTGTTTGTGCAGCGCTATTTCATTGCTGGCAAAGAATACGGCTTCCTTG
GCTGGGCATTCTATGCAGTGGTGTGTTTCATCGTGTCGGTCATTCTCGCGTGGGTGCTGTTTACCTTCGTTGATGATCCT
TTGATGAAGGCCACGGCGCGCAAGAAGGGGAGTAGGCGCTTGAAGCAGTCCAATATTTTGGTCCGTGACCTGAAAGTTCT
CTTCGGCAAAAGCCCCGAAAAGCCGTTAAAAGTTGAGACTCGCGCTGAGAATCTCACAGAAAACTCCGAAGCTCCCGCTA
AGGTAGCTACCGGAATCAAATCTTAG

Upstream 100 bases:

>100_bases
TTGATGCACGTGCAGAAATCGTCGGCGGTCCGTGGCACCCATCTGTTAAGGGAGACTCGGTTACTGCAGGGATCCTGCGA
GATCGAGTAAACGCCTAAAG

Downstream 100 bases:

>100_bases
GGAAGGAAAACATATGGCTATTTACCGTAAGCTTGCGGCTTCCGCTGCAGCACTGGCCCTGTCCGCATCACTGGTCGCTT
GTGGCGACTCTGAGGACACC

Product: acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MTSKSISGKRPNLPSLTGARWLAALAVYFLHALVFLSVYPFQQSELFATIHKFVPMQLGSAGVTFFFILSGFLIYWSNSQ
LKGMKNVLYYCKRRITKIYPMHLIALAMFIVASAKFTTTGITWVLDFARVELWLPNALLIHTWNPDWVTLGGLNVPSWSL
GAEMLFYLTFPLFIPLVRKVKGVGNWWAFGITFAVSLALITVIHFYADGPKGIENFFVPRLWDTNVSPVAEVHADPVWFM
QEEIPVLESYWLSYYFPLTRLIEFYLGVFGAKLVAEGMFKNTNITIPLIALAVSFVATWFVPLAFKMSVIMSLPMAFVVA
TLAVRDIEGKSGEIASPRAVLLGNISFAFYMVQFPVMVFVQRYFIAGKEYGFLGWAFYAVVCFIVSVILAWVLFTFVDDP
LMKATARKKGSRRLKQSNILVRDLKVLFGKSPEKPLKVETRAENLTENSEAPAKVATGIKS

Sequences:

>Translated_461_residues
MTSKSISGKRPNLPSLTGARWLAALAVYFLHALVFLSVYPFQQSELFATIHKFVPMQLGSAGVTFFFILSGFLIYWSNSQ
LKGMKNVLYYCKRRITKIYPMHLIALAMFIVASAKFTTTGITWVLDFARVELWLPNALLIHTWNPDWVTLGGLNVPSWSL
GAEMLFYLTFPLFIPLVRKVKGVGNWWAFGITFAVSLALITVIHFYADGPKGIENFFVPRLWDTNVSPVAEVHADPVWFM
QEEIPVLESYWLSYYFPLTRLIEFYLGVFGAKLVAEGMFKNTNITIPLIALAVSFVATWFVPLAFKMSVIMSLPMAFVVA
TLAVRDIEGKSGEIASPRAVLLGNISFAFYMVQFPVMVFVQRYFIAGKEYGFLGWAFYAVVCFIVSVILAWVLFTFVDDP
LMKATARKKGSRRLKQSNILVRDLKVLFGKSPEKPLKVETRAENLTENSEAPAKVATGIKS
>Mature_460_residues
TSKSISGKRPNLPSLTGARWLAALAVYFLHALVFLSVYPFQQSELFATIHKFVPMQLGSAGVTFFFILSGFLIYWSNSQL
KGMKNVLYYCKRRITKIYPMHLIALAMFIVASAKFTTTGITWVLDFARVELWLPNALLIHTWNPDWVTLGGLNVPSWSLG
AEMLFYLTFPLFIPLVRKVKGVGNWWAFGITFAVSLALITVIHFYADGPKGIENFFVPRLWDTNVSPVAEVHADPVWFMQ
EEIPVLESYWLSYYFPLTRLIEFYLGVFGAKLVAEGMFKNTNITIPLIALAVSFVATWFVPLAFKMSVIMSLPMAFVVAT
LAVRDIEGKSGEIASPRAVLLGNISFAFYMVQFPVMVFVQRYFIAGKEYGFLGWAFYAVVCFIVSVILAWVLFTFVDDPL
MKATARKKGSRRLKQSNILVRDLKVLFGKSPEKPLKVETRAENLTENSEAPAKVATGIKS

Specific function: Catalyzes the acylation of the mycaminose sugar during midecamycin biosynthesis [H]

COG id: COG1835

COG function: function code I; Predicted acyltransferases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002656 [H]

Pfam domain/function: PF01757 Acyl_transf_3 [H]

EC number: NA

Molecular weight: Translated: 51949; Mature: 51818

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKSISGKRPNLPSLTGARWLAALAVYFLHALVFLSVYPFQQSELFATIHKFVPMQLGS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
AGVTFFFILSGFLIYWSNSQLKGMKNVLYYCKRRITKIYPMHLIALAMFIVASAKFTTTG
CHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ITWVLDFARVELWLPNALLIHTWNPDWVTLGGLNVPSWSLGAEMLFYLTFPLFIPLVRKV
HHHHHHHHHHHEECCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KGVGNWWAFGITFAVSLALITVIHFYADGPKGIENFFVPRLWDTNVSPVAEVHADPVWFM
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHCCCCEEEH
QEEIPVLESYWLSYYFPLTRLIEFYLGVFGAKLVAEGMFKNTNITIPLIALAVSFVATWF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VPLAFKMSVIMSLPMAFVVATLAVRDIEGKSGEIASPRAVLLGNISFAFYMVQFPVMVFV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHH
QRYFIAGKEYGFLGWAFYAVVCFIVSVILAWVLFTFVDDPLMKATARKKGSRRLKQSNIL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VRDLKVLFGKSPEKPLKVETRAENLTENSEAPAKVATGIKS
HHHHHHHHCCCCCCCCEEEHHHHHCCCCCCCCHHHHCCCCC
>Mature Secondary Structure 
TSKSISGKRPNLPSLTGARWLAALAVYFLHALVFLSVYPFQQSELFATIHKFVPMQLGS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
AGVTFFFILSGFLIYWSNSQLKGMKNVLYYCKRRITKIYPMHLIALAMFIVASAKFTTTG
CHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ITWVLDFARVELWLPNALLIHTWNPDWVTLGGLNVPSWSLGAEMLFYLTFPLFIPLVRKV
HHHHHHHHHHHEECCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KGVGNWWAFGITFAVSLALITVIHFYADGPKGIENFFVPRLWDTNVSPVAEVHADPVWFM
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHCCCCEEEH
QEEIPVLESYWLSYYFPLTRLIEFYLGVFGAKLVAEGMFKNTNITIPLIALAVSFVATWF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VPLAFKMSVIMSLPMAFVVATLAVRDIEGKSGEIASPRAVLLGNISFAFYMVQFPVMVFV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHH
QRYFIAGKEYGFLGWAFYAVVCFIVSVILAWVLFTFVDDPLMKATARKKGSRRLKQSNIL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VRDLKVLFGKSPEKPLKVETRAENLTENSEAPAKVATGIKS
HHHHHHHHCCCCCCCCEEEHHHHHCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]