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The map label for this gene is recG [H]

Identifier: 62390208

GI number: 62390208

Start: 1392263

End: 1394386

Strand: Direct

Name: recG [H]

Synonym: cg1498

Alternate gene names: 62390208

Gene position: 1392263-1394386 (Clockwise)

Preceding gene: 62390207

Following gene: 62390209

Centisome position: 42.41

GC content: 57.44

Gene sequence:

>2124_bases
ATGTTGGGTTGGCATGACGAGCGTTTGCTCAAAGACATCCTTCCGGCAAAGGAAGCCACAGCGATTAAAAAGGCGCTGGG
CTACACCACTGCGGAAGAGTTGCTCCGCCACCATGTGCGCAAATACTCCCACCACGGCTCTGGCGTGGGAATTGGTGATG
CCACTGAGGGCGATCTTGTTACCATCGTGGGTCAGGTCGCCTTTGCCAAGCAGTCCTATACCCAGTCCGGCAAGATGCTG
TACAAGGTTACAGTCTTGACTGAGACGGAACGCATCGGCATTTCCTTCTTCGGAGCCAAGCACATTCCGCGTCTTCTCCC
AGAAGGCACTCGTGCGCTTTTTACCGGCAAGGTGAAGTTTTTTCGCAACGAACCTCAGCTATCTCATCCAGAGTTCATTG
TGATCCCAGATCCTGGATCAGGCCGCCGACTCACCGCCACTGGCGGTATGAAATCTCTGGCTGCCTACGGCGATGTGGAA
GAAGTGGCACTTCGTTTGGTGGATCGCGAATACATCCCGATCTATGCCGGCACCGCCACCATGACTACCTGGCGGATCAT
GGCTGCAGTGCAACGGGTACTGGAAACCATGCCGGTGATCAAAGAACCACTGAGCGTGGTGCCCGAAGGCATGCCCAGTT
TCGACGAGGCCATCCGCGGCATTCACGATCCAGGCCATGAATCTCCCAGCACGTTTATCAACCGTCTGAAATACAACGAA
GCACTATCGCTGGCCACGGTGATGGCGATCCGGCGTGCCGATACCAAGAACCGCAAAGCACCACCCATGCCGCGCGCACT
CAAAGGGCATCAGCACATGCTCATCGATGCACTCAACTTTCAGCTCACAGTGGGACAGAAGCAAGTGATCCGTGAGATCA
GCGCGGACATTGAACAACGCGTTCCCATGTCTCGTCTGCTCCAAGGTGAGGTTGGTTCGGGTAAAACCATCGTGTCGTTG
ATCGCGATGCTGCAGGCAATTGATTCCGGTAGGCAGTGCGCCATGCTCGCCCCGACGGAAGTGTTGGCCACCCAGCATGC
CCGCAGCCTGAGCAAAACTCTCGACGACGCAGGCCTTGATATCAATGTTGTGCTCTTGACTGGCTCGATGCCCACGGGAG
CCAAGAAGGAGGCTCTGCTGGAAATCATCTCCGGTGACGCAGACATTGTGGTCGGCACGCATGCGCTGATCCAGGACACC
GTGGAGTTCTTCGACCTTGGCCTCGTGGTGGTGGATGAGCAGCACCGTTTCGGCGTGGAGCAACGCGATCAACTGCGGAC
CAAGGGCAGGGAAGGCCTGACCCCGCACCTATTGGTTATGACTGCGACCCCAATTCCGCGCACCATCGCCATGACGGTGT
TCGGCGACTTGGCGGTGTCCACGTTGCGTGAACTTCCAGGCGGGCGCCGGCCGATTCAAACCTCGGTGATACCCGATCAC
AAACCTGGCTGGGTTAAACGCGGTTGGGAACGCATCGGTGAGGAAGTCCTCGCCGGACGCCAAGCCTATGTGGTGTGTCC
GCGCATTGAAGGCGAAGGCGGCGTGCTGGAAATCCACGCCTATCTTTCCGAACAGGTATATCCAGGATTGAATGTTGGAA
TGCTGCACGGTCGCATGGACACGGATCTCAAAGATTCGGTCATGCAGGAATTCGCCCAAGGTGAGATCGATATTTTGGTC
GCCACCACGGTCATTGAGGTCGGTATTGACGTTGCCAACGCCACCGTCATGCTCATCCGCGAGGCGGAACGCTTCGGCGT
TTCCCAGATCCACCAGCTGCGCGGCCGTGTTGGCCGTGGGCAGCACGATTCCCTCTGCCTGCTGCACACCACCTTCGACG
AGGACTCCCCACAAGGCCAACGCCTCGCCGCAATTTCCACCACAACCGACGGTTTTCAACTCTCTGAACTTGATTTGCAG
GTACGCCAAGAAGGCGACGTGTTGGGCACCCGCCAGTCCGGCAGCGACACCAAACTCCGTCACCTCTCGTTTATCAGCGA
CCAAAAAATCATCGAGCGTGCGCTTATCGACGCCACCGAGCTGGTTGCCGCCAGCCGTTCCAGGGCGCTTGAGCTGGTCA
GCGACATCGCAATGATCAACCAGGAATACCTGGAAAAGAGCTGA

Upstream 100 bases:

>100_bases
GTTTTCCGCCGTGGCCTGGGAACTCACACGGATGTGGAGATCACGGTCTATCCTGCTACTGGAATGGAGAATCTGGTAGA
GATCGGAGTGGAGTAGCCAC

Downstream 100 bases:

>100_bases
TATTGATAGGGTTTAAGTCATGAAGATCTACGCACCTTTTGCTGGAATCGTCCACTATTTTGTCGATGAAGGCGATCCCG
TGGAAACCGGCATGCAACTG

Product: RecG-like helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 707

Protein sequence:

>707_residues
MLGWHDERLLKDILPAKEATAIKKALGYTTAEELLRHHVRKYSHHGSGVGIGDATEGDLVTIVGQVAFAKQSYTQSGKML
YKVTVLTETERIGISFFGAKHIPRLLPEGTRALFTGKVKFFRNEPQLSHPEFIVIPDPGSGRRLTATGGMKSLAAYGDVE
EVALRLVDREYIPIYAGTATMTTWRIMAAVQRVLETMPVIKEPLSVVPEGMPSFDEAIRGIHDPGHESPSTFINRLKYNE
ALSLATVMAIRRADTKNRKAPPMPRALKGHQHMLIDALNFQLTVGQKQVIREISADIEQRVPMSRLLQGEVGSGKTIVSL
IAMLQAIDSGRQCAMLAPTEVLATQHARSLSKTLDDAGLDINVVLLTGSMPTGAKKEALLEIISGDADIVVGTHALIQDT
VEFFDLGLVVVDEQHRFGVEQRDQLRTKGREGLTPHLLVMTATPIPRTIAMTVFGDLAVSTLRELPGGRRPIQTSVIPDH
KPGWVKRGWERIGEEVLAGRQAYVVCPRIEGEGGVLEIHAYLSEQVYPGLNVGMLHGRMDTDLKDSVMQEFAQGEIDILV
ATTVIEVGIDVANATVMLIREAERFGVSQIHQLRGRVGRGQHDSLCLLHTTFDEDSPQGQRLAAISTTTDGFQLSELDLQ
VRQEGDVLGTRQSGSDTKLRHLSFISDQKIIERALIDATELVAASRSRALELVSDIAMINQEYLEKS

Sequences:

>Translated_707_residues
MLGWHDERLLKDILPAKEATAIKKALGYTTAEELLRHHVRKYSHHGSGVGIGDATEGDLVTIVGQVAFAKQSYTQSGKML
YKVTVLTETERIGISFFGAKHIPRLLPEGTRALFTGKVKFFRNEPQLSHPEFIVIPDPGSGRRLTATGGMKSLAAYGDVE
EVALRLVDREYIPIYAGTATMTTWRIMAAVQRVLETMPVIKEPLSVVPEGMPSFDEAIRGIHDPGHESPSTFINRLKYNE
ALSLATVMAIRRADTKNRKAPPMPRALKGHQHMLIDALNFQLTVGQKQVIREISADIEQRVPMSRLLQGEVGSGKTIVSL
IAMLQAIDSGRQCAMLAPTEVLATQHARSLSKTLDDAGLDINVVLLTGSMPTGAKKEALLEIISGDADIVVGTHALIQDT
VEFFDLGLVVVDEQHRFGVEQRDQLRTKGREGLTPHLLVMTATPIPRTIAMTVFGDLAVSTLRELPGGRRPIQTSVIPDH
KPGWVKRGWERIGEEVLAGRQAYVVCPRIEGEGGVLEIHAYLSEQVYPGLNVGMLHGRMDTDLKDSVMQEFAQGEIDILV
ATTVIEVGIDVANATVMLIREAERFGVSQIHQLRGRVGRGQHDSLCLLHTTFDEDSPQGQRLAAISTTTDGFQLSELDLQ
VRQEGDVLGTRQSGSDTKLRHLSFISDQKIIERALIDATELVAASRSRALELVSDIAMINQEYLEKS
>Mature_707_residues
MLGWHDERLLKDILPAKEATAIKKALGYTTAEELLRHHVRKYSHHGSGVGIGDATEGDLVTIVGQVAFAKQSYTQSGKML
YKVTVLTETERIGISFFGAKHIPRLLPEGTRALFTGKVKFFRNEPQLSHPEFIVIPDPGSGRRLTATGGMKSLAAYGDVE
EVALRLVDREYIPIYAGTATMTTWRIMAAVQRVLETMPVIKEPLSVVPEGMPSFDEAIRGIHDPGHESPSTFINRLKYNE
ALSLATVMAIRRADTKNRKAPPMPRALKGHQHMLIDALNFQLTVGQKQVIREISADIEQRVPMSRLLQGEVGSGKTIVSL
IAMLQAIDSGRQCAMLAPTEVLATQHARSLSKTLDDAGLDINVVLLTGSMPTGAKKEALLEIISGDADIVVGTHALIQDT
VEFFDLGLVVVDEQHRFGVEQRDQLRTKGREGLTPHLLVMTATPIPRTIAMTVFGDLAVSTLRELPGGRRPIQTSVIPDH
KPGWVKRGWERIGEEVLAGRQAYVVCPRIEGEGGVLEIHAYLSEQVYPGLNVGMLHGRMDTDLKDSVMQEFAQGEIDILV
ATTVIEVGIDVANATVMLIREAERFGVSQIHQLRGRVGRGQHDSLCLLHTTFDEDSPQGQRLAAISTTTDGFQLSELDLQ
VRQEGDVLGTRQSGSDTKLRHLSFISDQKIIERALIDATELVAASRSRALELVSDIAMINQEYLEKS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=693, Percent_Identity=35.3535353535354, Blast_Score=323, Evalue=2e-89,
Organism=Escherichia coli, GI1787357, Length=425, Percent_Identity=33.6470588235294, Blast_Score=215, Evalue=8e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77665; Mature: 77665

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGWHDERLLKDILPAKEATAIKKALGYTTAEELLRHHVRKYSHHGSGVGIGDATEGDLV
CCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
TIVGQVAFAKQSYTQSGKMLYKVTVLTETERIGISFFGAKHIPRLLPEGTRALFTGKVKF
EHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEECHHHHHHHCCCCCCEEEEEEEEE
FRNEPQLSHPEFIVIPDPGSGRRLTATGGMKSLAAYGDVEEVALRLVDREYIPIYAGTAT
EECCCCCCCCCEEEEECCCCCCEEEECCCHHHHHHCCCHHHHHHHHHCCCCEEEEECCHH
MTTWRIMAAVQRVLETMPVIKEPLSVVPEGMPSFDEAIRGIHDPGHESPSTFINRLKYNE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHH
ALSLATVMAIRRADTKNRKAPPMPRALKGHQHMLIDALNFQLTVGQKQVIREISADIEQR
HHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEEEECEEEECCHHHHHHHHHHHHHHC
VPMSRLLQGEVGSGKTIVSLIAMLQAIDSGRQCAMLAPTEVLATQHARSLSKTLDDAGLD
CCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCE
INVVLLTGSMPTGAKKEALLEIISGDADIVVGTHALIQDTVEFFDLGLVVVDEQHRFGVE
EEEEEEECCCCCCCHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCEEEECCHHHCCCC
QRDQLRTKGREGLTPHLLVMTATPIPRTIAMTVFGDLAVSTLRELPGGRRPIQTSVIPDH
HHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCC
KPGWVKRGWERIGEEVLAGRQAYVVCPRIEGEGGVLEIHAYLSEQVYPGLNVGMLHGRMD
CCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEHHHHHCCCCCCEEEECCCCC
TDLKDSVMQEFAQGEIDILVATTVIEVGIDVANATVMLIREAERFGVSQIHQLRGRVGRG
CCHHHHHHHHHHCCCEEEEEEHHHHHHCCCCCCEEEEEEHHHHHCCHHHHHHHHHHCCCC
QHDSLCLLHTTFDEDSPQGQRLAAISTTTDGFQLSELDLQVRQEGDVLGTRQSGSDTKLR
CCCCEEEEEEECCCCCCCCCEEEEEEECCCCEEEEHHHHHHHCCCCEEECCCCCCCCHHH
HLSFISDQKIIERALIDATELVAASRSRALELVSDIAMINQEYLEKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLGWHDERLLKDILPAKEATAIKKALGYTTAEELLRHHVRKYSHHGSGVGIGDATEGDLV
CCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
TIVGQVAFAKQSYTQSGKMLYKVTVLTETERIGISFFGAKHIPRLLPEGTRALFTGKVKF
EHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEECHHHHHHHCCCCCCEEEEEEEEE
FRNEPQLSHPEFIVIPDPGSGRRLTATGGMKSLAAYGDVEEVALRLVDREYIPIYAGTAT
EECCCCCCCCCEEEEECCCCCCEEEECCCHHHHHHCCCHHHHHHHHHCCCCEEEEECCHH
MTTWRIMAAVQRVLETMPVIKEPLSVVPEGMPSFDEAIRGIHDPGHESPSTFINRLKYNE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHH
ALSLATVMAIRRADTKNRKAPPMPRALKGHQHMLIDALNFQLTVGQKQVIREISADIEQR
HHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEEEECEEEECCHHHHHHHHHHHHHHC
VPMSRLLQGEVGSGKTIVSLIAMLQAIDSGRQCAMLAPTEVLATQHARSLSKTLDDAGLD
CCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCE
INVVLLTGSMPTGAKKEALLEIISGDADIVVGTHALIQDTVEFFDLGLVVVDEQHRFGVE
EEEEEEECCCCCCCHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCEEEECCHHHCCCC
QRDQLRTKGREGLTPHLLVMTATPIPRTIAMTVFGDLAVSTLRELPGGRRPIQTSVIPDH
HHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCC
KPGWVKRGWERIGEEVLAGRQAYVVCPRIEGEGGVLEIHAYLSEQVYPGLNVGMLHGRMD
CCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEHHHHHCCCCCCEEEECCCCC
TDLKDSVMQEFAQGEIDILVATTVIEVGIDVANATVMLIREAERFGVSQIHQLRGRVGRG
CCHHHHHHHHHHCCCEEEEEEHHHHHHCCCCCCEEEEEEHHHHHCCHHHHHHHHHHCCCC
QHDSLCLLHTTFDEDSPQGQRLAAISTTTDGFQLSELDLQVRQEGDVLGTRQSGSDTKLR
CCCCEEEEEEECCCCCCCCCEEEEEEECCCCEEEEHHHHHHHCCCCEEECCCCCCCCHHH
HLSFISDQKIIERALIDATELVAASRSRALELVSDIAMINQEYLEKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]