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The map label for this gene is ycgM [C]

Identifier: 62390176

GI number: 62390176

Start: 1359726

End: 1360532

Strand: Direct

Name: ycgM [C]

Synonym: cg1458

Alternate gene names: 62390176

Gene position: 1359726-1360532 (Clockwise)

Preceding gene: 62390175

Following gene: 62390177

Centisome position: 41.42

GC content: 54.65

Gene sequence:

>807_bases
ATGCGTTTTGGACGAATTGCCACCCCAGATGGAATGTGTTTTTGCTCAATTGAAGGCGAAGGCGATGATGTAGCTAACCT
CACCGCCCGTGAGATCGAGGGTACCCCCTTCACTGAACCAAAGTTCACCGGTCGCGAATGGCCACTTAAAGATGTACGCC
TGCTGGCACCAATGCTGCCAAGCAAAGTCGTCGCGATTGGCCGTAACTACGCCGATCACGTTGCTGAGGTGTTTAAGAAG
TCCGCAGAATCACTGCCACCAACCCTGTTCCTGAAGCCACCAACAGCTGTCACCGGACCAGAGTCCCCAATCCGAATCCC
TTCCTTTGCCACCAAGGTGGAATTCGAAGGTGAGCTCGCAGTAGTTATCGGCAAGCCCTGCAAGAACGTCAAGGCTGATG
ACTGGAAGTCTGTCGTTTTGGGCTTCACCATCATCAACGACGTCTCCTCCCGTGACCTCCAGTTCGCTGACGGCCAGTGG
GCACGCGCTAAGGGCATTGACACCTTCGGCCCCATCGGACCATGGATTGAAACTGACATCAACTCCATCGACTTGGACAA
CCTGCCCATCAAGGCACGCCTCACCCACGACGGCGAAACCCAATTGAAGCAGGACTCCAACTCCAACCAGATGATCATGA
AGATGGGCGAAATTATCGAGTTCATCACCGCCTCCATGACCCTGCTCCCAGGCGACGTTATTGCAACCGGTTCTCCAGCA
GGCACCGAAGCAATGGTTGACGGCGACTACATCGAAATCGAAATTCCAGGCATCGGCAAGCTGGGCAACCCAGTTGTGGA
CGCCTAA

Upstream 100 bases:

>100_bases
TTTGGTGCAGATCACGCACCTTCGGGCGAACACCCTCAAAGATATTTGGGAATAGGGGTCATCGTGCAGGCCCCCACACC
CAACGCGTAACATAACGGTC

Downstream 100 bases:

>100_bases
AATGGATCACCACCATCACGATCATGGGGAGAAGCGTCCGTACGACCAGGTCACCCCAGAATCCATGGAGAATCAATACA
CCACCACGGAACAAGTCTGG

Product: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MRFGRIATPDGMCFCSIEGEGDDVANLTAREIEGTPFTEPKFTGREWPLKDVRLLAPMLPSKVVAIGRNYADHVAEVFKK
SAESLPPTLFLKPPTAVTGPESPIRIPSFATKVEFEGELAVVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFADGQW
ARAKGIDTFGPIGPWIETDINSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFITASMTLLPGDVIATGSPA
GTEAMVDGDYIEIEIPGIGKLGNPVVDA

Sequences:

>Translated_268_residues
MRFGRIATPDGMCFCSIEGEGDDVANLTAREIEGTPFTEPKFTGREWPLKDVRLLAPMLPSKVVAIGRNYADHVAEVFKK
SAESLPPTLFLKPPTAVTGPESPIRIPSFATKVEFEGELAVVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFADGQW
ARAKGIDTFGPIGPWIETDINSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFITASMTLLPGDVIATGSPA
GTEAMVDGDYIEIEIPGIGKLGNPVVDA
>Mature_268_residues
MRFGRIATPDGMCFCSIEGEGDDVANLTAREIEGTPFTEPKFTGREWPLKDVRLLAPMLPSKVVAIGRNYADHVAEVFKK
SAESLPPTLFLKPPTAVTGPESPIRIPSFATKVEFEGELAVVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFADGQW
ARAKGIDTFGPIGPWIETDINSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFITASMTLLPGDVIATGSPA
GTEAMVDGDYIEIEIPGIGKLGNPVVDA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=233, Percent_Identity=37.7682403433476, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI40786394, Length=233, Percent_Identity=38.6266094420601, Blast_Score=134, Evalue=6e-32,
Organism=Homo sapiens, GI215422413, Length=205, Percent_Identity=33.6585365853659, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=34, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI13654274, Length=200, Percent_Identity=34, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1787428, Length=201, Percent_Identity=32.3383084577114, Blast_Score=95, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17557057, Length=201, Percent_Identity=31.3432835820896, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324161, Length=226, Percent_Identity=29.646017699115, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28572127, Length=268, Percent_Identity=32.089552238806, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24663695, Length=228, Percent_Identity=35.5263157894737, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28571789, Length=208, Percent_Identity=35.5769230769231, Blast_Score=108, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 29001; Mature: 29001

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFGRIATPDGMCFCSIEGEGDDVANLTAREIEGTPFTEPKFTGREWPLKDVRLLAPMLP
CCCCCCCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
SKVVAIGRNYADHVAEVFKKSAESLPPTLFLKPPTAVTGPESPIRIPSFATKVEFEGELA
HHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEECCCCEEEEEECCCEE
VVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFADGQWARAKGIDTFGPIGPWIETDI
EEECCCCCCCCCCCHHHHEEEEHEECCCCCCCEEECCCCCHHHCCCCCCCCCCCCHHCCC
NSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFITASMTLLPGDVIATGSPA
CEEECCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
GTEAMVDGDYIEIEIPGIGKLGNPVVDA
CCCEEECCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MRFGRIATPDGMCFCSIEGEGDDVANLTAREIEGTPFTEPKFTGREWPLKDVRLLAPMLP
CCCCCCCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
SKVVAIGRNYADHVAEVFKKSAESLPPTLFLKPPTAVTGPESPIRIPSFATKVEFEGELA
HHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEECCCCEEEEEECCCEE
VVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFADGQWARAKGIDTFGPIGPWIETDI
EEECCCCCCCCCCCHHHHEEEEHEECCCCCCCEEECCCCCHHHCCCCCCCCCCCCHHCCC
NSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFITASMTLLPGDVIATGSPA
CEEECCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
GTEAMVDGDYIEIEIPGIGKLGNPVVDA
CCCEEECCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]