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The map label for this gene is bcpA [H]

Identifier: 62389948

GI number: 62389948

Start: 1110463

End: 1111158

Strand: Direct

Name: bcpA [H]

Synonym: cg1206

Alternate gene names: 62389948

Gene position: 1110463-1111158 (Clockwise)

Preceding gene: 62389947

Following gene: 62389949

Centisome position: 33.83

GC content: 57.9

Gene sequence:

>696_bases
ATGTCTGACCTGAAGTCACTTGCCACGAAATTTGCTAGCGATCATGAATCCGGAAAGCTGCTGGTCCTGCCTACCGTCTG
GGATACCTGGAGCGCGGGGCTCGTAGAAGAAGCAGGATTTAGTGGCCTGACCATTGGTAGCCACCCAGTCGCGGATGCGA
CAGGAAGCTCCGATGGTGAAAACATGAATTTTGCAGATTATATGGCGGTGGTCAAGAAGATCACCTCGGCGGTATCCATC
CCCGTAAGCGTTGATGTGGAATCCGGTTATGGTCTCTCGCCTGCGGATTTGATCGCACAGATTTTGGAAGCTGGCGCAGT
GGGCATCAATGTGGAAGATGTTGTGCACAGCGAGGGTAAGCGTGTTCGTGAGGCGCAGGAGCACGCTGATTACATCGCTG
CGGCACGTCAAGCTGCCGATGTGGCAGGTGTAGATGTGGTGATCAACGGTCGCACGGATGCCGTCAAACTTGGTGCAGAC
GTTTTTGAAGATCCGATGGTGGAGGCCATCAAGCGCATCAAGCTCATGGAACAGGCAGGCGCGCGTTCGGTGTACCCCGT
GGGTCTGAGCACCGCCGAGCAGGTTGAGCGCCTGGTGGACGCTGTGTCAGTGCCGGTCAACATCACCGCGCACCCGGTTG
ATGGGCACGGCGCAGGCGATCTGGCCACCCTCGCAGGCCTTGCGTGCGCCGCGTGA

Upstream 100 bases:

>100_bases
TTGGCCACTTGTTTGAGTAGGCTGGCGGGCAGGTGCTTGAAATACTCTGATTAGTTCCAAGCAAATTAGCACAACTTCAC
ACTTTATTTAGGAGCATGTT

Downstream 100 bases:

>100_bases
CCTTCGGTCCGCTCTGGCAAAAATGGCTGGCTGCCACCTCGGCGCAGCAGCTTAAGGGCTGGGCTTAAATTGCTTGTCGA
CGCCTAGTGCCACAATGGAG

Product: PEP phosphonomutase or related enzyme

Products: NA

Alternate protein names: Carboxyphosphonoenolpyruvate phosphonomutase; CPEP phosphonomutase [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSDLKSLATKFASDHESGKLLVLPTVWDTWSAGLVEEAGFSGLTIGSHPVADATGSSDGENMNFADYMAVVKKITSAVSI
PVSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSEGKRVREAQEHADYIAAARQAADVAGVDVVINGRTDAVKLGAD
VFEDPMVEAIKRIKLMEQAGARSVYPVGLSTAEQVERLVDAVSVPVNITAHPVDGHGAGDLATLAGLACAA

Sequences:

>Translated_231_residues
MSDLKSLATKFASDHESGKLLVLPTVWDTWSAGLVEEAGFSGLTIGSHPVADATGSSDGENMNFADYMAVVKKITSAVSI
PVSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSEGKRVREAQEHADYIAAARQAADVAGVDVVINGRTDAVKLGAD
VFEDPMVEAIKRIKLMEQAGARSVYPVGLSTAEQVERLVDAVSVPVNITAHPVDGHGAGDLATLAGLACAA
>Mature_230_residues
SDLKSLATKFASDHESGKLLVLPTVWDTWSAGLVEEAGFSGLTIGSHPVADATGSSDGENMNFADYMAVVKKITSAVSIP
VSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSEGKRVREAQEHADYIAAARQAADVAGVDVVINGRTDAVKLGADV
FEDPMVEAIKRIKLMEQAGARSVYPVGLSTAEQVERLVDAVSVPVNITAHPVDGHGAGDLATLAGLACAA

Specific function: Catalyzes the formation of an unusual C-P bond that is involved in the biosynthesis of the antibiotic bialaphos (BA). Catalyzes the rearrangement of the carboxyphosphono group of CPEP to form the C-P bond of phosphinopyruvate [H]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate lyase/PEP mutase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786525, Length=189, Percent_Identity=30.1587301587302, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012697
- InterPro:   IPR000918
- InterPro:   IPR018523
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00463 ICL [H]

EC number: =2.7.8.23 [H]

Molecular weight: Translated: 23864; Mature: 23733

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLKSLATKFASDHESGKLLVLPTVWDTWSAGLVEEAGFSGLTIGSHPVADATGSSDGE
CCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
NMNFADYMAVVKKITSAVSIPVSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSEGK
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCHH
RVREAQEHADYIAAARQAADVAGVDVVINGRTDAVKLGADVFEDPMVEAIKRIKLMEQAG
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHCHHHHHHHHHHHHHHHHHHHHCC
ARSVYPVGLSTAEQVERLVDAVSVPVNITAHPVDGHGAGDLATLAGLACAA
CCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SDLKSLATKFASDHESGKLLVLPTVWDTWSAGLVEEAGFSGLTIGSHPVADATGSSDGE
CHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
NMNFADYMAVVKKITSAVSIPVSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSEGK
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCHH
RVREAQEHADYIAAARQAADVAGVDVVINGRTDAVKLGADVFEDPMVEAIKRIKLMEQAG
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHCHHHHHHHHHHHHHHHHHHHHCC
ARSVYPVGLSTAEQVERLVDAVSVPVNITAHPVDGHGAGDLATLAGLACAA
CCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2160937; 1320191; 1330557; 3611020 [H]