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The map label for this gene is ychM [C]

Identifier: 62389939

GI number: 62389939

Start: 1101429

End: 1103126

Strand: Direct

Name: ychM [C]

Synonym: cg1195

Alternate gene names: 62389939

Gene position: 1101429-1103126 (Clockwise)

Preceding gene: 62389937

Following gene: 62389940

Centisome position: 33.55

GC content: 52.65

Gene sequence:

>1698_bases
ATGCGGGGCTATCAACGATCCTGGTTGAAGGGTGATGTCATCGCGGGTATAACCGTGGCCGCGTACTTGGTTCCACAAGT
CATGGCTTATGCCGTCATTGCGGGGCTGCCAGCTGTCGTTGGTCTGTGGGGAGTTCTGGCTCCCATGGCGCTGTACTTTT
TCTTGGGCACGTCTCGAAATCTCTCGGTTGGTCCTGAATCAACCACCGCTCTGATGACGGCTGCAGGTGTGGGAGCTTTA
GTCGGGGCAGCTGGCGGGCCTGAACGATACGCAGAAGTAGCGGCACTATTGGCTATTGCAGTGGGCATTGTATGCGCTGT
TGGTTTTATTGGCCGATTGGGATTTCTTACCAGGCTGTTGTCTCGACCGGTGCTCGTTGGATATTTGATCGGTATTGCAG
TCTTGATGATCGTCAGTCAGCTGTCCAAAGTCACCCAGGTGAATGTGGAGAGCGGTCAGACGTGGCAGGAAATAATATCG
TTTATCAAAGTAGCTGGCCAGGCACATATTCCTACAGTGATTTTGGCAGTCGTGGTGTTGAGCTTGCTGTATCTGGCAAA
TTGGTTGACGCCTAAATTTCCCAGCACACTCATGGTTCTTCTGCTTTCGGCAGCCGCGGTGGGGTTTTTTCATCTGGATA
GGTTTGGTCTTGAGGTCATTGGTGAGGTGCCCCGTGGCCTGCCTCAACCAAGTATTCCCTCGATTGGCGATCTAGAGATC
TGGTCGTTGTTGCCCTATGCCGTGGGTATTGCCATCGTTGGTTTTTCAGACAATGTGTTGACTGCTCGTGCATTCGCGTC
GGGAAAAGATGAGGTGATTGATTCCAACCAGGAGCTGCTCGCACTGGGAACCGCAAACCTGGCGAATGGGTTCTTCCAGG
GATTTCCTGTGTCATCGAGTGGCTCCCGAACTGTTCTTGGAGACACGGCAGGTGCTCGCACTCAGGTGCATTCACTTGTC
GTGGTGGCGCTGGTGATCATGGTGCTGTTGTTTGCTGGTCCTGTGCTCGAGTCTTTCCCAGATGCGGCACTTGGCGCCTT
AGTTATTTATGCAGCAACGCAGTTGATTGATATCGCAGAGATCAAAAGGATCGCACGTTTCCGCAAGAGCGAGTTGGTCA
TCACAGCGGCTACTGCTGCATCCGTTGTGGCTTCTGGCGTGCTCGCGGGGATCGGCGTTGCGGTTACGTTGTCCATCTTG
GATCTCATCAGACGTATTACCCGACCTTATGCCGATGTCCTAGGATATACGCCGGGCATGGCTGGAATGCACAGCTTGGA
GGATTATCCTGAGTCGACAGCAGTCGAAGGGCTCGTGGTTTTTAGATACGATTCCCCACTGTTTTTCGCCAACGCTGATG
ATTTTTCCAAACGTGCCATCGAAGCCGTTGATGAAGCAACTCAACCCGTGCATTGGTTTTTACTGAATGCTGAAGCGAAT
ACGGAAGTTGATCTCACGGCCGTCGATGCCATGGAAGCACTTCGCAAAACCCTGGAGGAACGGGGTATCCGATTTGCGAT
GGCCCGGGTGAAGCAAGATCTACGCCGAAGCCTCGAGCCTGCAGGTTTCATTGAATCCGTGGGGGAGGAGTACATTTTCG
CCACACTCCCCACTGCAGTCAAGGGGTATTCCGTGGAGTTTCGCGATCGTTTTGGAAACTATCCAGAAGGCGTTCCGAAA
GAAATTTTGGAACTTTAA

Upstream 100 bases:

>100_bases
TATTAGCAAAACTTCTTAAAGAGCCTTTTTGTGCCTTTATCCGAGTATCTTTAAAAGCATGAGTATTAAGTGGGCGCGCT
TTGTACCGGGGATAACCGCG

Downstream 100 bases:

>100_bases
GCTGCCTGGTTGGCGGACTTAGTCATGAATCAACTTGTTGGATTTCATCTCTTTAATGAGGATTACAACGTCAATGATCA
TCTGCGAAATACGGCCTTCA

Product: MFS superfamily sulfate permease

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MRGYQRSWLKGDVIAGITVAAYLVPQVMAYAVIAGLPAVVGLWGVLAPMALYFFLGTSRNLSVGPESTTALMTAAGVGAL
VGAAGGPERYAEVAALLAIAVGIVCAVGFIGRLGFLTRLLSRPVLVGYLIGIAVLMIVSQLSKVTQVNVESGQTWQEIIS
FIKVAGQAHIPTVILAVVVLSLLYLANWLTPKFPSTLMVLLLSAAAVGFFHLDRFGLEVIGEVPRGLPQPSIPSIGDLEI
WSLLPYAVGIAIVGFSDNVLTARAFASGKDEVIDSNQELLALGTANLANGFFQGFPVSSSGSRTVLGDTAGARTQVHSLV
VVALVIMVLLFAGPVLESFPDAALGALVIYAATQLIDIAEIKRIARFRKSELVITAATAASVVASGVLAGIGVAVTLSIL
DLIRRITRPYADVLGYTPGMAGMHSLEDYPESTAVEGLVVFRYDSPLFFANADDFSKRAIEAVDEATQPVHWFLLNAEAN
TEVDLTAVDAMEALRKTLEERGIRFAMARVKQDLRRSLEPAGFIESVGEEYIFATLPTAVKGYSVEFRDRFGNYPEGVPK
EILEL

Sequences:

>Translated_565_residues
MRGYQRSWLKGDVIAGITVAAYLVPQVMAYAVIAGLPAVVGLWGVLAPMALYFFLGTSRNLSVGPESTTALMTAAGVGAL
VGAAGGPERYAEVAALLAIAVGIVCAVGFIGRLGFLTRLLSRPVLVGYLIGIAVLMIVSQLSKVTQVNVESGQTWQEIIS
FIKVAGQAHIPTVILAVVVLSLLYLANWLTPKFPSTLMVLLLSAAAVGFFHLDRFGLEVIGEVPRGLPQPSIPSIGDLEI
WSLLPYAVGIAIVGFSDNVLTARAFASGKDEVIDSNQELLALGTANLANGFFQGFPVSSSGSRTVLGDTAGARTQVHSLV
VVALVIMVLLFAGPVLESFPDAALGALVIYAATQLIDIAEIKRIARFRKSELVITAATAASVVASGVLAGIGVAVTLSIL
DLIRRITRPYADVLGYTPGMAGMHSLEDYPESTAVEGLVVFRYDSPLFFANADDFSKRAIEAVDEATQPVHWFLLNAEAN
TEVDLTAVDAMEALRKTLEERGIRFAMARVKQDLRRSLEPAGFIESVGEEYIFATLPTAVKGYSVEFRDRFGNYPEGVPK
EILEL
>Mature_565_residues
MRGYQRSWLKGDVIAGITVAAYLVPQVMAYAVIAGLPAVVGLWGVLAPMALYFFLGTSRNLSVGPESTTALMTAAGVGAL
VGAAGGPERYAEVAALLAIAVGIVCAVGFIGRLGFLTRLLSRPVLVGYLIGIAVLMIVSQLSKVTQVNVESGQTWQEIIS
FIKVAGQAHIPTVILAVVVLSLLYLANWLTPKFPSTLMVLLLSAAAVGFFHLDRFGLEVIGEVPRGLPQPSIPSIGDLEI
WSLLPYAVGIAIVGFSDNVLTARAFASGKDEVIDSNQELLALGTANLANGFFQGFPVSSSGSRTVLGDTAGARTQVHSLV
VVALVIMVLLFAGPVLESFPDAALGALVIYAATQLIDIAEIKRIARFRKSELVITAATAASVVASGVLAGIGVAVTLSIL
DLIRRITRPYADVLGYTPGMAGMHSLEDYPESTAVEGLVVFRYDSPLFFANADDFSKRAIEAVDEATQPVHWFLLNAEAN
TEVDLTAVDAMEALRKTLEERGIRFAMARVKQDLRRSLEPAGFIESVGEEYIFATLPTAVKGYSVEFRDRFGNYPEGVPK
EILEL

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=481, Percent_Identity=27.2349272349272, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI39752683, Length=481, Percent_Identity=27.2349272349272, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI94721259, Length=478, Percent_Identity=30.7531380753138, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI94721255, Length=478, Percent_Identity=30.7531380753138, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI94721253, Length=478, Percent_Identity=30.7531380753138, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI94721257, Length=478, Percent_Identity=30.7531380753138, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4557535, Length=494, Percent_Identity=27.3279352226721, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI47131207, Length=645, Percent_Identity=26.5116279069767, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI20336272, Length=645, Percent_Identity=26.5116279069767, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI4505697, Length=486, Percent_Identity=27.1604938271605, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI269784651, Length=480, Percent_Identity=25.4166666666667, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI45827802, Length=429, Percent_Identity=27.2727272727273, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI16418413, Length=549, Percent_Identity=24.408014571949, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI217272867, Length=549, Percent_Identity=24.408014571949, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI100913030, Length=621, Percent_Identity=23.5104669887279, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI262206105, Length=603, Percent_Identity=26.2023217247098, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI262206075, Length=603, Percent_Identity=26.2023217247098, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI262206069, Length=603, Percent_Identity=26.2023217247098, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI262206063, Length=603, Percent_Identity=26.2023217247098, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI20336282, Length=496, Percent_Identity=24.3951612903226, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI16306483, Length=496, Percent_Identity=24.3951612903226, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI65506789, Length=367, Percent_Identity=28.6103542234332, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI16418457, Length=503, Percent_Identity=20.8747514910537, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI301601599, Length=503, Percent_Identity=20.8747514910537, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI301601602, Length=213, Percent_Identity=22.5352112676056, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI45827804, Length=249, Percent_Identity=23.2931726907631, Blast_Score=73, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17551690, Length=606, Percent_Identity=27.2277227722772, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17566848, Length=556, Percent_Identity=27.3381294964029, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI86564196, Length=609, Percent_Identity=24.9589490968801, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17562578, Length=606, Percent_Identity=26.2376237623762, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI86565215, Length=550, Percent_Identity=26.5454545454545, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI86564876, Length=646, Percent_Identity=22.9102167182663, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI193203292, Length=493, Percent_Identity=26.369168356998, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI86565209, Length=244, Percent_Identity=27.8688524590164, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI86565211, Length=244, Percent_Identity=27.8688524590164, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI86565213, Length=246, Percent_Identity=28.8617886178862, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325260, Length=585, Percent_Identity=24.4444444444444, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6323121, Length=462, Percent_Identity=26.4069264069264, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319771, Length=463, Percent_Identity=25.0539956803456, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24649801, Length=444, Percent_Identity=27.7027027027027, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24666186, Length=392, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21358229, Length=440, Percent_Identity=27.0454545454545, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI85815873, Length=432, Percent_Identity=26.3888888888889, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24651449, Length=455, Percent_Identity=25.2747252747253, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24647160, Length=439, Percent_Identity=24.373576309795, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21355087, Length=441, Percent_Identity=24.2630385487528, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24663084, Length=542, Percent_Identity=25.4612546125461, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21357695, Length=542, Percent_Identity=25.4612546125461, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI19922482, Length=557, Percent_Identity=23.1597845601436, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21358633, Length=441, Percent_Identity=26.530612244898, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 60103; Mature: 60103

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCEEHHHHCCCCCCCCCHHHHCC
>Mature Secondary Structure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CCCCEEHHHHCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]