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The map label for this gene is aroF

Identifier: 62389880

GI number: 62389880

Start: 1048080

End: 1049180

Strand: Direct

Name: aroF

Synonym: cg1129

Alternate gene names: 62389880

Gene position: 1048080-1049180 (Clockwise)

Preceding gene: 62389879

Following gene: 62389881

Centisome position: 31.93

GC content: 56.13

Gene sequence:

>1101_bases
ATGAGTTCTCCAGTCTCACTCGAAAACGCGGCGTCAACCAGCAACAAGCGCGTCGTGGCTTTCCACGAGCTGCCTAGCCC
TACAGATCTCATCGCCGCAAACCCACTGACACCAAAGCAGGCTTCCAAGGTGGAGCAGGATCGCCAGGACATCGCTGATA
TCTTCGCTGGCGACGATGACCGCCTCGTTGTCGTTGTGGGACCTTGCTCAGTTCACGATCCTGAAGCAGCCATCGATTAC
GCAAACCGCCTGGCTCCGCTGGCAAAGCGCCTTGATCAGGACCTCAAGATTGTCATGCGCGTGTACTTCGAGAAGCCTCG
CACCATCGTCGGATGGAAGGGATTGATCAATGATCCTCACCTCAACGAAACCTACGACATCCCAGAGGGCTTGCGCATTG
CGCGCAAAGTGCTTATCGACGTTGTGAACCTTGATCTCCCAGTCGGCTGCGAATTCCTCGAACCAAACAGCCCTCAGTAC
TACGCCGACACTGTCGCATGGGGAGCAATCGGCGCTCGTACCACCGAATCTCAGGTGCACCGCCAGCTGGCTTCTGGGAT
GTCTATGCCAATTGGTTTCAAGAACGGAACTGACGGAAACATCCAGGTTGCAGTCGACGCGGTACAGGCTGCCCAGAACC
CACACTTCTTCTTCGGAACCTCCGACGACGGCGCGCTGAGCGTCGTGGAGACCGCAGGCAACAGCAACTCCCACATCATT
TTGCGCGGCGGTACCTCCGGCCCGAATCATGATGCAGCTTCGGTGGAGGCCGTCGTCGAGAAGCTTGGTGAAAACGCTCG
TCTCATGATCGATGCTTCCCATGCTAACTCCGGCAAGGATCATATCCGACAGGTTGAGGTTGTTCGTGAAATCGCAGAGC
AGATTTCTGGCGGTTCTGAAGCTGTGGCTGGAATCATGATTGAGTCCTTCCTCGTTGGTGGCGCACAGAACCTTGATCCT
GCGAAATTGCGCATCAATGGCGGTGAAGGCCTGGTGTACGGACAGTCTGTGACCGATAAGTGCATCGATATTGACACCAC
CATCGATTTGCTCGCTGAGCTGGCCGCAGCAGTAAGGGAACGCCGAGCAGCAGCCAAGTAA

Upstream 100 bases:

>100_bases
AACCGGAGTCGAGCAGCACCTCCCCGCAAGGGTAGAGGGGCTGCTTTTTTGTTTCCTAAATTCACCCCATCCCATGCATA
GCCCTGAAAGGCAAGAAAAA

Downstream 100 bases:

>100_bases
TTAAGGGCGCTAGACTGTTAAATGTGTTAAACCTGCCCAGACTGCTGTACCCGGTGTATGAGCGCCGTCTTTTAAGAGAA
CTAGACGGCGCCAAACAGCC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSSPVSLENAASTSNKRVVAFHELPSPTDLIAANPLTPKQASKVEQDRQDIADIFAGDDDRLVVVVGPCSVHDPEAAIDY
ANRLAPLAKRLDQDLKIVMRVYFEKPRTIVGWKGLINDPHLNETYDIPEGLRIARKVLIDVVNLDLPVGCEFLEPNSPQY
YADTVAWGAIGARTTESQVHRQLASGMSMPIGFKNGTDGNIQVAVDAVQAAQNPHFFFGTSDDGALSVVETAGNSNSHII
LRGGTSGPNHDAASVEAVVEKLGENARLMIDASHANSGKDHIRQVEVVREIAEQISGGSEAVAGIMIESFLVGGAQNLDP
AKLRINGGEGLVYGQSVTDKCIDIDTTIDLLAELAAAVRERRAAAK

Sequences:

>Translated_366_residues
MSSPVSLENAASTSNKRVVAFHELPSPTDLIAANPLTPKQASKVEQDRQDIADIFAGDDDRLVVVVGPCSVHDPEAAIDY
ANRLAPLAKRLDQDLKIVMRVYFEKPRTIVGWKGLINDPHLNETYDIPEGLRIARKVLIDVVNLDLPVGCEFLEPNSPQY
YADTVAWGAIGARTTESQVHRQLASGMSMPIGFKNGTDGNIQVAVDAVQAAQNPHFFFGTSDDGALSVVETAGNSNSHII
LRGGTSGPNHDAASVEAVVEKLGENARLMIDASHANSGKDHIRQVEVVREIAEQISGGSEAVAGIMIESFLVGGAQNLDP
AKLRINGGEGLVYGQSVTDKCIDIDTTIDLLAELAAAVRERRAAAK
>Mature_365_residues
SSPVSLENAASTSNKRVVAFHELPSPTDLIAANPLTPKQASKVEQDRQDIADIFAGDDDRLVVVVGPCSVHDPEAAIDYA
NRLAPLAKRLDQDLKIVMRVYFEKPRTIVGWKGLINDPHLNETYDIPEGLRIARKVLIDVVNLDLPVGCEFLEPNSPQYY
ADTVAWGAIGARTTESQVHRQLASGMSMPIGFKNGTDGNIQVAVDAVQAAQNPHFFFGTSDDGALSVVETAGNSNSHIIL
RGGTSGPNHDAASVEAVVEKLGENARLMIDASHANSGKDHIRQVEVVREIAEQISGGSEAVAGIMIESFLVGGAQNLDPA
KLRINGGEGLVYGQSVTDKCIDIDTTIDLLAELAAAVRERRAAAK

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family

Homologues:

Organism=Escherichia coli, GI1786969, Length=349, Percent_Identity=52.1489971346705, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1788953, Length=334, Percent_Identity=48.8023952095808, Blast_Score=337, Evalue=8e-94,
Organism=Escherichia coli, GI1787996, Length=352, Percent_Identity=46.875, Blast_Score=331, Evalue=4e-92,
Organism=Saccharomyces cerevisiae, GI6319726, Length=360, Percent_Identity=49.7222222222222, Blast_Score=345, Evalue=5e-96,
Organism=Saccharomyces cerevisiae, GI6320240, Length=357, Percent_Identity=47.6190476190476, Blast_Score=332, Evalue=8e-92,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROG_CORGL (P35170)

Other databases:

- EMBL:   L07603
- EMBL:   BA000036
- EMBL:   BX927151
- PIR:   I40837
- RefSeq:   NP_600217.1
- RefSeq:   YP_225282.1
- ProteinModelPortal:   P35170
- SMR:   P35170
- GeneID:   1018979
- GeneID:   3343015
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg1129
- KEGG:   cgl:NCgl0950
- HOGENOM:   HBG670536
- OMA:   ADTVAWG
- PhylomeDB:   P35170
- ProtClustDB:   PRK09261
- BioCyc:   CGLU196627:CG1129-MONOMER
- BRENDA:   2.5.1.54
- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR21225
- PIRSF:   PIRSF001361
- TIGRFAMs:   TIGR00034

Pfam domain/function: PF00793 DAHP_synth_1

EC number: =2.5.1.54

Molecular weight: Translated: 39131; Mature: 39000

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPVSLENAASTSNKRVVAFHELPSPTDLIAANPLTPKQASKVEQDRQDIADIFAGDDD
CCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
RLVVVVGPCSVHDPEAAIDYANRLAPLAKRLDQDLKIVMRVYFEKPRTIVGWKGLINDPH
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
LNETYDIPEGLRIARKVLIDVVNLDLPVGCEFLEPNSPQYYADTVAWGAIGARTTESQVH
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEHHHHHHCCCCCCCHHHHH
RQLASGMSMPIGFKNGTDGNIQVAVDAVQAAQNPHFFFGTSDDGALSVVETAGNSNSHII
HHHHCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCEEEECCCCCCEEEEEECCCCCCEEE
LRGGTSGPNHDAASVEAVVEKLGENARLMIDASHANSGKDHIRQVEVVREIAEQISGGSE
EECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHH
AVAGIMIESFLVGGAQNLDPAKLRINGGEGLVYGQSVTDKCIDIDTTIDLLAELAAAVRE
HHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCCCCHHEECCHHHHHHHHHHHHHHH
RRAAAK
HHHCCC
>Mature Secondary Structure 
SSPVSLENAASTSNKRVVAFHELPSPTDLIAANPLTPKQASKVEQDRQDIADIFAGDDD
CCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
RLVVVVGPCSVHDPEAAIDYANRLAPLAKRLDQDLKIVMRVYFEKPRTIVGWKGLINDPH
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
LNETYDIPEGLRIARKVLIDVVNLDLPVGCEFLEPNSPQYYADTVAWGAIGARTTESQVH
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEHHHHHHCCCCCCCHHHHH
RQLASGMSMPIGFKNGTDGNIQVAVDAVQAAQNPHFFFGTSDDGALSVVETAGNSNSHII
HHHHCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCEEEECCCCCCEEEEEECCCCCCEEE
LRGGTSGPNHDAASVEAVVEKLGENARLMIDASHANSGKDHIRQVEVVREIAEQISGGSE
EECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHH
AVAGIMIESFLVGGAQNLDPAKLRINGGEGLVYGQSVTDKCIDIDTTIDLLAELAAAVRE
HHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCCCCHHEECCHHHHHHHHHHHHHHH
RRAAAK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8097175; 12948626