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The map label for this gene is ybdL [H]

Identifier: 62389704

GI number: 62389704

Start: 863063

End: 864226

Strand: Direct

Name: ybdL [H]

Synonym: cg0931

Alternate gene names: 62389704

Gene position: 863063-864226 (Clockwise)

Preceding gene: 62389703

Following gene: 62389708

Centisome position: 26.29

GC content: 53.35

Gene sequence:

>1164_bases
ATGAGTAATGACTTCGTCGTTTCTAGGCTTAGACCCTTTGGTGAAACGATTTTTGCAACCATGACCCAGCGAGCTGTTGA
GGCGGGTGCAATCAATCTTGGTCAGGGCTTTCCTGATGAGGATGGTCCTCGTCGGATGTTAGAGATCGCGTCGGAGCAGA
TTCTCGGGGGAAATAATCAGTATTCGGCGGGGCGTGGGGATGCTTCGTTGAGGGCAGCTGTGGCTCGTGATCATTTGGAG
AGGTTTGATCTGGAGTACAACCCTGATTCGGAGGTGTTGATCACGGTGGGGGCCACTGAGGCGATTACGGCGACTGTGTT
GGGTTTGGTGGAGCCTGGGGATGAAGTGATCGTTTTGGAACCGTATTACGATGCGTATGCGGCGGCTATTGCGTTGGCGG
GGGCGACGCGGGTGGCGGTTCCTTTGCAGGAGGTGGAGAACTCGTGGGATGTGGATGTCGATAAGTTGCATGCGGCGGTG
ACTAAGAAGACGCGGATGATTATCGTTAATTCGCCGCATAATCCGACGGGTTCGGTGTTTTCTAAGAAGGCGTTGAAGCA
GTTGGCGGGTGTTGCTCGTGCGTATGACTTGTTGGTGTTGTCAGATGAGGTGTATGAGCATCTTGTTTTTGATGATCAGA
AGCATGTGAGTGTCGCGAAGCTGCCCGGTATGTGGGATCGCACGGTGACGGTGTCGTCGGCGGCGAAAACGTTCAATGTG
ACTGGTTGGAAGACGGGGTGGGCGTTGGCACCGGAGCCGTTGTTGGAGGCGGTGTTGAAGGCGAAGCAGTTTATGTCTTA
TGTGGGGGCTACACCTTTTCAGCCGGCTGTGGCGCATGCGATTGAACATGAGCAGAAGTGGGTGTCAAAGATGTCTAAGG
GGCTTGAGCTCAAGCGGGATATTTTGCGTACTGCGTTAGATAAGGCGGGGCTGAAGACTCATGACAGTATGGGCACGTAT
TTCATCGTTGCGGATATTGGGGATCGTGATGGTGCGGAGTTCTGTTTTGAGTTGATTGAGAAGGTTGGGGTGGCGGCGAT
TCCGGTGCAGGCGTTTGTGGATCATCCGAAGAAGTGGTCGTCGAAGGTTCGTTTTGCGTTTTGCAAAAAAGAAGAGACGC
TCCGCGAAGCTGCGGAGCGTCTCAAGGGGATTAAGAAACTATAG

Upstream 100 bases:

>100_bases
CGCGGCACGCACGCTGGGGGCAAGCGTCGACAAGCACAAACTTTTTGCTTAATTGAATCCTTTGCGCACCAATCAATGGG
GGATCAAATATAGTAGCTGC

Downstream 100 bases:

>100_bases
TTTGAACAGGTTGTTGGGGGTCTTTTTAACGTCCTCCAACTTGCCGCGGTTCTTTTCTAGTTTGGCCCAGAGTTCGTGGG
GGATAGTTTTCTCGGCTTCA

Product: aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSNDFVVSRLRPFGETIFATMTQRAVEAGAINLGQGFPDEDGPRRMLEIASEQILGGNNQYSAGRGDASLRAAVARDHLE
RFDLEYNPDSEVLITVGATEAITATVLGLVEPGDEVIVLEPYYDAYAAAIALAGATRVAVPLQEVENSWDVDVDKLHAAV
TKKTRMIIVNSPHNPTGSVFSKKALKQLAGVARAYDLLVLSDEVYEHLVFDDQKHVSVAKLPGMWDRTVTVSSAAKTFNV
TGWKTGWALAPEPLLEAVLKAKQFMSYVGATPFQPAVAHAIEHEQKWVSKMSKGLELKRDILRTALDKAGLKTHDSMGTY
FIVADIGDRDGAEFCFELIEKVGVAAIPVQAFVDHPKKWSSKVRFAFCKKEETLREAAERLKGIKKL

Sequences:

>Translated_387_residues
MSNDFVVSRLRPFGETIFATMTQRAVEAGAINLGQGFPDEDGPRRMLEIASEQILGGNNQYSAGRGDASLRAAVARDHLE
RFDLEYNPDSEVLITVGATEAITATVLGLVEPGDEVIVLEPYYDAYAAAIALAGATRVAVPLQEVENSWDVDVDKLHAAV
TKKTRMIIVNSPHNPTGSVFSKKALKQLAGVARAYDLLVLSDEVYEHLVFDDQKHVSVAKLPGMWDRTVTVSSAAKTFNV
TGWKTGWALAPEPLLEAVLKAKQFMSYVGATPFQPAVAHAIEHEQKWVSKMSKGLELKRDILRTALDKAGLKTHDSMGTY
FIVADIGDRDGAEFCFELIEKVGVAAIPVQAFVDHPKKWSSKVRFAFCKKEETLREAAERLKGIKKL
>Mature_386_residues
SNDFVVSRLRPFGETIFATMTQRAVEAGAINLGQGFPDEDGPRRMLEIASEQILGGNNQYSAGRGDASLRAAVARDHLER
FDLEYNPDSEVLITVGATEAITATVLGLVEPGDEVIVLEPYYDAYAAAIALAGATRVAVPLQEVENSWDVDVDKLHAAVT
KKTRMIIVNSPHNPTGSVFSKKALKQLAGVARAYDLLVLSDEVYEHLVFDDQKHVSVAKLPGMWDRTVTVSSAAKTFNVT
GWKTGWALAPEPLLEAVLKAKQFMSYVGATPFQPAVAHAIEHEQKWVSKMSKGLELKRDILRTALDKAGLKTHDSMGTYF
IVADIGDRDGAEFCFELIEKVGVAAIPVQAFVDHPKKWSSKVRFAFCKKEETLREAAERLKGIKKL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=405, Percent_Identity=35.0617283950617, Blast_Score=254, Evalue=7e-68,
Organism=Homo sapiens, GI56713256, Length=405, Percent_Identity=35.0617283950617, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI95147551, Length=420, Percent_Identity=33.3333333333333, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI169881279, Length=420, Percent_Identity=33.3333333333333, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=34.1059602649007, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI4507369, Length=197, Percent_Identity=32.994923857868, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI149944424, Length=205, Percent_Identity=29.2682926829268, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4885351, Length=188, Percent_Identity=33.5106382978723, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI19263340, Length=187, Percent_Identity=32.620320855615, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI215599424, Length=187, Percent_Identity=32.620320855615, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI187936925, Length=205, Percent_Identity=27.8048780487805, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI14211921, Length=205, Percent_Identity=27.8048780487805, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1786816, Length=389, Percent_Identity=38.3033419023136, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI1788722, Length=388, Percent_Identity=27.8350515463918, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1788627, Length=194, Percent_Identity=31.4432989690722, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787909, Length=201, Percent_Identity=25.8706467661692, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787710, Length=197, Percent_Identity=32.994923857868, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=405, Percent_Identity=35.0617283950617, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI71994476, Length=405, Percent_Identity=35.0617283950617, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17567369, Length=403, Percent_Identity=33.0024813895782, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17567663, Length=363, Percent_Identity=23.6914600550964, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=34.1085271317829, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6320317, Length=359, Percent_Identity=23.3983286908078, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=209, Percent_Identity=29.1866028708134, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573069, Length=412, Percent_Identity=35.6796116504854, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24646114, Length=412, Percent_Identity=35.6796116504854, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI28573067, Length=412, Percent_Identity=35.6796116504854, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI28573065, Length=412, Percent_Identity=35.6796116504854, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI18859735, Length=201, Percent_Identity=28.8557213930348, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI45551451, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641770, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641760, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641768, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641766, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641764, Length=314, Percent_Identity=24.8407643312102, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 42444; Mature: 42313

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDFVVSRLRPFGETIFATMTQRAVEAGAINLGQGFPDEDGPRRMLEIASEQILGGNNQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCC
YSAGRGDASLRAAVARDHLERFDLEYNPDSEVLITVGATEAITATVLGLVEPGDEVIVLE
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEC
PYYDAYAAAIALAGATRVAVPLQEVENSWDVDVDKLHAAVTKKTRMIIVNSPHNPTGSVF
CCHHHHHHHHHHHCCHHEEEEHHHHCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCHHH
SKKALKQLAGVARAYDLLVLSDEVYEHLVFDDQKHVSVAKLPGMWDRTVTVSSAAKTFNV
HHHHHHHHHHHHHHHHHEEECHHHHHHHHCCCCCCEEHHHCCCCCCCEEEEECCCCEEEC
TGWKTGWALAPEPLLEAVLKAKQFMSYVGATPFQPAVAHAIEHEQKWVSKMSKGLELKRD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
ILRTALDKAGLKTHDSMGTYFIVADIGDRDGAEFCFELIEKVGVAAIPVQAFVDHPKKWS
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCHHHH
SKVRFAFCKKEETLREAAERLKGIKKL
CCHHEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNDFVVSRLRPFGETIFATMTQRAVEAGAINLGQGFPDEDGPRRMLEIASEQILGGNNQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCC
YSAGRGDASLRAAVARDHLERFDLEYNPDSEVLITVGATEAITATVLGLVEPGDEVIVLE
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEC
PYYDAYAAAIALAGATRVAVPLQEVENSWDVDVDKLHAAVTKKTRMIIVNSPHNPTGSVF
CCHHHHHHHHHHHCCHHEEEEHHHHCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCHHH
SKKALKQLAGVARAYDLLVLSDEVYEHLVFDDQKHVSVAKLPGMWDRTVTVSSAAKTFNV
HHHHHHHHHHHHHHHHHEEECHHHHHHHHCCCCCCEEHHHCCCCCCCEEEEECCCCEEEC
TGWKTGWALAPEPLLEAVLKAKQFMSYVGATPFQPAVAHAIEHEQKWVSKMSKGLELKRD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
ILRTALDKAGLKTHDSMGTYFIVADIGDRDGAEFCFELIEKVGVAAIPVQAFVDHPKKWS
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCHHHH
SKVRFAFCKKEETLREAAERLKGIKKL
CCHHEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]