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The map label for this gene is mtrA [H]

Identifier: 62389642

GI number: 62389642

Start: 792205

End: 792885

Strand: Direct

Name: mtrA [H]

Synonym: cg0862

Alternate gene names: 62389642

Gene position: 792205-792885 (Clockwise)

Preceding gene: 62389641

Following gene: 62389643

Centisome position: 24.13

GC content: 55.8

Gene sequence:

>681_bases
ATGTCACAGAAAATTCTCGTGGTTGATGATGATCCCGCCATCTCCGAGATGCTCACCATCGTGCTCAGCGCAGAAGGCTT
TGACACCGTAGCTGTCACCGACGGCGCACTCGCCGTGGAAACCGCCTCCCGGGAACAACCGGATCTGATTTTGCTCGACT
TGATGCTTCCAGGCATGAACGGCATCGACATTTGTCGCCTCATCCGCCAAGAATCCTCCGTACCCATCATCATGCTCACC
GCCAAAACCGACACCGTTGATGTGGTGCTCGGTTTGGAATCCGGTGCAGACGATTACGTGAACAAGCCTTTCAAAGCGAA
AGAACTTGTCGCCCGCATCCGTGCCCGCCTCCGCGCAACCGTGGACGAGCCCAGCGAAATCATCGAAGTCGGCGATCTGT
CCATCGACGTCCCAGCACACACCGTCAAACGAAACGGCGCTGAGATTTCCTTGACCCCACTCGAATTCGACCTCCTGCTG
GAACTCGCCCGCAAACCACAGCAAGTATTCACCCGTGAAGAATTGCTGGGCAAAGTGTGGGGCTACCGCCACGCATCCGA
CACTCGACTGGTCAACGTTCACGTTCAGCGTCTGCGCGCCAAGATTGAAAAAGATCCAGAAAATCCGCAGATCGTCCTCA
CCGTCCGCGGTGTTGGCTACAAAACTGGCCACAACGATTAA

Upstream 100 bases:

>100_bases
GATCGTGGTTGCCCCTGATGAAGACCCCGGCCACGTTGCGCAGAGAATCGTGGAATTCCTGGGTACTATAAACTAATCCC
AATTAGCAGGAAGGATTCTC

Downstream 100 bases:

>100_bases
GTTTTTCATTTAAAAAAGGGGCAGTTTCTCATTCTTGCCTGGCTCACGCGACTTCGACATCGCATTGTAGATAAATGGCG
AACCTCACTGCAGGTTCGCG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSQKILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMNGIDICRLIRQESSVPIIMLT
AKTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRATVDEPSEIIEVGDLSIDVPAHTVKRNGAEISLTPLEFDLLL
ELARKPQQVFTREELLGKVWGYRHASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGHND

Sequences:

>Translated_226_residues
MSQKILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMNGIDICRLIRQESSVPIIMLT
AKTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRATVDEPSEIIEVGDLSIDVPAHTVKRNGAEISLTPLEFDLLL
ELARKPQQVFTREELLGKVWGYRHASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGHND
>Mature_225_residues
SQKILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMNGIDICRLIRQESSVPIIMLTA
KTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRATVDEPSEIIEVGDLSIDVPAHTVKRNGAEISLTPLEFDLLLE
LARKPQQVFTREELLGKVWGYRHASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGHND

Specific function: Member of the two-component regulatory system mtrA/mtrB [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=42.6666666666667, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=38.7665198237885, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI87082012, Length=217, Percent_Identity=39.63133640553, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=37.219730941704, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=38.5650224215247, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=41.8181818181818, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=34.3891402714932, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=33.1858407079646, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=40, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=34.8623853211009, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=33.9366515837104, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=30.1369863013699, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=35.5140186915888, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=35.1851851851852, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787487, Length=150, Percent_Identity=27.3333333333333, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24943; Mature: 24812

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMN
CCCEEEEEECCHHHHHHHHHHEECCCCCEEEEECCEEEEEECCCCCCCEEEEEEECCCCC
GIDICRLIRQESSVPIIMLTAKTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRAT
HHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHCC
VDEPSEIIEVGDLSIDVPAHTVKRNGAEISLTPLEFDLLLELARKPQQVFTREELLGKVW
CCCHHHHEEECCEEEECCHHHHHCCCCEEEEECCHHHHHHHHHHCHHHHHHHHHHHHHHH
GYRHASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGHND
CCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SQKILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMN
CCEEEEEECCHHHHHHHHHHEECCCCCEEEEECCEEEEEECCCCCCCEEEEEEECCCCC
GIDICRLIRQESSVPIIMLTAKTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRAT
HHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHCC
VDEPSEIIEVGDLSIDVPAHTVKRNGAEISLTPLEFDLLLELARKPQQVFTREELLGKVW
CCCHHHHEEECCEEEECCHHHHHCCCCEEEEECCHHHHHHHHHHCHHHHHHHHHHHHHHH
GYRHASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGHND
CCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]